Sucrose low endotoxin USP NF, BP EP Ph Eur Manufacturers, with SDS GHS MSDS Sheet

Supplier, Manufacturer, Exporter of Sucrose low endotoxin, Muby Chemicals of Mubychem Group, established in 1976, is the original manufacturers of Specialty Chemicals, Pharmaceutical Excipient, Fragrance Food & Flavor chemicals, Reagent Grade Chemicals, Shale Gas Fracturing Chemicals in India. Mubychem Group has several manufacturing facilities spread across Western India and world wide contacts and toll manufacturers. We are exporting globally to countries like USA, Canada, Europe, UAE, South Africa, Tanzania, Kenya, Egypt, Nigeria, Cameroon, Uganda, Turkey, Mexico, Brazil, Chile, Argentina, Dubai, Korea, Vietnam, Thailand, Malaysia, Indonesia, Australia, China, Germany, France, Italy, Portugal, Bangladesh, etc.

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Sucrose: CAS Number: 57-50-1, EINECS EC Number: 200-334-9, Molecular Formula: C12H22O11, Molecular Weight: 342.30, HS Code ---**

Specifications, Safety Data Sheet, Manufacturing process details, Wholesale retail buy sell prices, Uses etc available on line in these pages for Sucrose.

Sucrose is common sugar. It is a disaccharide, a molecule composed of two monosaccharides: glucose and fructose. Sucrose is produced naturally in plants, from which table sugar is refined. For human consumption, sucrose is extracted and refined from either sugarcane or sugar beet or Caster.

General Properties and Specifications of Sucrose or Sugar low endotoxin Beet and Cane Derived:
Appearance: White crystals or powder or granules.
Assay: 99.5% minimum.
Loss on drying at105C: 0.2% maximum.
Relative density: around 1.6
Melting point: Decomposes at 186C.
Solubility: Soluble in water.

Specifications of Sucrose USP NF Grade:
C12H22O11 342.30
α -D-Glucopyranoside, β -D-fructofuranosyl-.Sucrose [CAS 57-50-1].

Sucrose is a sugar obtained from Saccharum officinarum Linné (Fam. Gramineae), Beta vulgaris Linné (Fam. Chenopodiaceae), and other sources. It contains no added substances.

Packaging and storage: Preserve in well-closed containers.
Specific rotation: not less than +65.9 .
Residue on ignition: not more than 0.05%, a 5-g specimen being used.
Chloride: A 2.0-g portion shows no more chloride than corresponds to 0.10 mL of 0.020 N hydrochloric acid (0.0035%).
Sulfate: A 5.0-g portion shows no more sulfate than corresponds to 0.30 mL of 0.020 N sulfuric acid (0.006%).
Calcium: To 10 mL of a solution (1 in 10) add 1 mL of ammonium oxalate TS: the solution remains clear for at least 1 minute.
Heavy metals: the limit is 5 ppm.
Invert sugar: Dissolve 20 g in water to make 100 mL, and filter if necessary. Place 50 mL of the clear liquid in a 250-mL beaker, add 50 mL of alkaline cupric tartrate, cover the beaker with a watch glass, and heat the mixture at such a rate that it comes to a boil in approximately 4 minutes, and boil for 2 minutes, accurately timed. Add at once 100 mL of cold, recently boiled water, and immediately collect the precipitated cuprous oxide on a tared filtering crucible containing a sintered-glass disk of medium pore size, or suitable equivalent. Thoroughly wash the residue on the filter with hot water, then with 10 mL of alcohol, and finally with 10 mL of ether, and dry at 105C for 1 hour: the weight of the cuprous oxide does not exceed 112 mg.

Specifications of Sucrose BP Ph Eur Grade:
Refined Sugar
C12H22O11 --- 342.3 --- CAS 57-50-1
Action and use: Sweetening agent.
Preparation: Syrup

DEFINITION
β-D-Fructofuranosyl α-D-glucopyranoside.
It contains no additives.

CHARACTERS
Appearance: White or almost white, crystalline powder, or lustrous, colourless or white or almost white crystals.
Solubility: Very soluble in water, slightly soluble in ethanol (96 per cent), practically insoluble in anhydrous ethanol.

IDENTIFICATION
First identification: A
Second identification: B, C
A. Infrared absorption spectrophotometry: Comparison sucrose CRS.
B. Thin-layer chromatography: To pass the test.
C. Dilute 1 mL of solution S (see Tests) to 100 mL with water. To 5 mL of the solution add 0.15 mL of freshly prepared copper sulfate solution and 2 mL of freshly prepared dilute sodium hydroxide solution. The solution is blue and clear and remains so after boiling. To the hot solution add 4 mL of dilute hydrochloric acid and boil for 1 min. Add 4 mL of dilute sodium hydroxide solution. An orange precipitate is formed immediately.

TESTS
Solution S: Dissolve 50.0 g in water R and dilute to 100 mL with the same solvent.
Appearance of solution: Solution S is clear.
Conductivity: Maximum 35 microS/cm at 20C.
Specific optical rotation: + 66.3 to + 67.0.
Colour value: Maximum 45.
Dextrins: If intended for use in the manufacture of large-volume parenteral preparations, it complies with the test for dextrins. To 2 mL of solution S add 8 mL of water, 0.05 mL of dilute hydrochloric acid and 0.05 mL of 0.05 M iodine. The solution remains yellow.
Reducing sugars: To 5 mL of solution S in a test-tube about 150 mm long and 16 mm in diameter add 5 mL of water, 1.0 mL of 1 M sodium hydroxide and 1.0 mL of a 1 g/L solution of methylene blue. Mix and place in a water-bath. After exactly 2 min, take the tube out of the bath and examine the solution immediately. The blue colour does not disappear completely. Ignore any blue colour at the air/solution interface.
Sulfites: Maximum 10 ppm, calculated as SO2.
Loss on drying: Maximum 0.1 per cent, determined on 2.000 g by drying in an oven at 105C for 3 h.
Bacterial endotoxins: Less than 0.25 IU/mg, if intended for use in the manufacture of large-volume parenteral preparations.

LABELLING
The label states, where applicable, that the substance is suitable for use in the manufacture of large-volume parenteral preparations.

Specifications of Sucrose FCC Food Grade:
Sugar; Granulated Sugar; Cane Sugar; Beet Sugar; β-D-Fructofuranosyl-α-D-glucopyranoside
C12H22O11 Formula weight 342.30
CAS [57-50-1

DESCRIPTION
Sucrose, in its processed form, occurs as a white, crystalline solid. It is obtained for commercial use from sugar cane and sugar beets. It is very soluble in water, in formamide, and in dimethyl sulfoxide and is slightly soluble in ethanol.
Function: Nutritive sweetener; formulation and texturizing aid.

REQUIREMENTS
Identification: A sample meets the requirements under Optical (Specific) Rotation.
Assay: Not less than 99.8 and not more than 100.2 International Sugar Degrees.
Arsenic: Not more than 1 mg/kg.
Color: Not more than 75 IU.
Invert Sugar: Not more than 0.1%.
Lead: Not more than 0.1 mg/kg.
Loss on Drying: Not more than 0.1%.
Optical (Specific) Rotation [α]D20°: Between +65.9° and +66.7°.
Residue on Ignition: Not more than 0.15%.

Specifications of Sucrose Analytical Reagent Grade:
C12H22O11 --- Formula Weight 342.30
CAS Number 57-50-1

For Original Monographs of IP Indian Pharmacopoeia BP British Pharmacopoeia USP US Pharmacopoeia FCC Food Grade product, please check with the respective web-pages or books.

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Sucrose SDS GHS, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet 20-Nov-20

Product Name & Other Names: Sucrose, α -D-Glucopyranoside, β -D-fructofuranosyl-.Sucrose.
CAS Number: 57-50-1
EINECS EC Code: 200-334-9
Relevant uses and uses advised against (if any): Industrial Manufacturing.
Suppliers: As per letterhead.

GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Hazard Class and Category Code(s), Regulation (EC) No 1272/2008 (CLP)

Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
This substance is not classified as dangerous according to Directive 67/548/EEC.

Hazards not otherwise classified (HNOC):
May causes mild skin irritation.
May causes mild eye irritation.

Precautionary statements:
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P262: Do not get in eyes, on skin, or on clothing.
P281: Use personal protective equipment as required.
P302+P352: IF ON SKIN: Wash with plenty of soap and water.
P303+P361+P353: IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+313: If eye irritation persists get medical advice/attention.

Product Name & Other Names: Sucrose, α -D-Glucopyranoside, β -D-fructofuranosyl- Sucrose.
CAS Number: 57-50-1
EINECS EC Code: 200-334-9

Skin: Rinse with water. Soap may be used. Seek Medical Aid.
Eyes: Wash eyes with plenty of water for at least 15 minutes, lifting lids occasionally. Seek Medical Aid.
Inhalation: Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Ingestion: If swallowed, induce vomiting immediately after giving two glasses of water. Never give anything by mouth to an unconscious person.

Flammability of the Product: Non-flammable.
Products of Combustion: Fumes and oxides of Carbon.
Fire Fighting Media and Instructions: Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. Wear self-contained breathing apparatus for firefighting if necessary.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes. Fire-extinguishing work is done from the windward and the suitable fire-extinguishing method according to the surrounding situation is used. Uninvolved persons should evacuate to a safe place.

Personal precautions, protective equipment and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Ensure adequate ventilation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil or water sources.
Methods and materials used for containment Cleanup procedures and Storage:
Small Spill: Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to legal requirements.
Large Spill: Contain spilled material. Do not inhale vapors, mist, or gas. Avoid dust formation. Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and allow to evacuate as per law.

Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. Wash thoroughly after handling. Do not drink, eat or smoke while handling. Avoid contact with skin, eyes and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cool, dry and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Do not leave the material container open. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like oxidizing agents.

Exposure Guidelines: This product does not contain any hazardous materials with occupational exposure limits established by the region-specific regulatory bodies.
Engineering Controls: Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to airborne contaminants below the exposure limit.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Dust deposits on floors and other surfaces may pick up moisture and cause the surfaces to become slippery and present safety hazards. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.

Physical state and appearance: Solid white crystals powder or granules.
Odor: Not available.
Odor threshold: Not available.
pH: 5.5 - 7 at 342 g/l at 25C.
Relative density: around 1.6
Melting point/freezing point: Decomposes at 186C.
Initial boiling point and boiling range: Not available.
Flash point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility: Soluble in water.
Viscosity: Not available.
Molecular Formula: C12H22O11
Molecular Weight: 342.30

Stability: It is stable in room temperature in closed containers under normal storage & handling.
Conditions of instability: Incompatible materials, Moisture
Incompatibility with various substances: Avoid high temperatures, sparks, open flames and moisture. Avoid contact with strong oxidizing agents and acids.
Polymerization: Will not occur.

LD50 Oral - Rat: 29700 mg/kg
Carcinogenic Effects: Not a reported carcinogen by IARC, NTP, ACGIH, OSHA.
Reproductive toxicity: No data available.
Teratogenicity: No data available.
Developmental Effects: No data available.

Toxicity to fish: No data available.
BOD5 and COD: Not available.
Mobility: Will likely be mobile in the environment due to its water solubility.
Persistence and Degradability: No information available. However unlikely to persist.
Bioaccumulation/ Accumulation: No information available. However unlikely to accumulate.

Waste Disposal: Waste must be disposed of in accordance with federal, state and local environmental control regulations.

DOT USA, TDG Canada & ADR/RID Europe: Not dangerous goods.
IMDG/IMO: Not dangerous goods.
IATA: Not dangerous goods.

USA Regulations:
SARA 313: Not applicable
SARA 311/312 Hazard Categories: Not applicable
California Prop 65: California No Significant Risk Level: None of the chemicals in this product are listed.

Disclaimer:
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Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
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