CAP, Cellulose Acetate Phthalate or Cellacefate Manufacturers, with SDS GHS MSDS Sheet
Supplier, Manufacturer, Exporter of AP, Cellulose Acetate Phthalate or Cellacefate, Muby Chemicals of Mubychem Group, established in 1976, is the original manufacturers of Specialty Chemicals, Pharmaceutical Excipient, Fragrance Food & Flavor chemicals, Reagent Grade Chemicals, Shale Gas Fracturing Chemicals in India. Mubychem Group has several manufacturing facilities spread across Western India and world wide contacts and toll manufacturers. We are exporting globally to countries like USA, Canada, Europe, UAE, South Africa, Tanzania, Kenya, Egypt, Nigeria, Cameroon, Uganda, Turkey, Mexico, Brazil, Chile, Argentina, Dubai, Korea, Vietnam, Thailand, Malaysia, Indonesia, Australia, China, Germany, France, Italy, Portugal etc.
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CAP, Cellulose Acetate Phthalate or Cellacefate: CAS Number: 9004-38-0, EINECS EC Number: yyyyy, Molecular Formula: Variable, Molecular Weight: Variable, HS Code ---**
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SDS MSDS Sheet of CAP, Cellulose Acetate Phthalate or Cellacefate Manufacturers
Cellulose Acetate Phthalate
Cellacefate CAP Pure Suppliers
Cellulose acetate phthalate (CAP), also known as cellacefate and cellulosi acetas phthalas, is a commonly used polymer phthalate in the formulation of pharmaceuticals, such as the enteric coating of tablets or capsules and for controlled release formulations. It is a hygroscopic white to off-white free-flowing powder, granules, or flakes. It is tasteless and odorless, though may have a weak odor of acetic acid. Cellulose acetate phthalate has been used for several decades as a pharmaceutical excipient due to its solubility dependent on the pH of the aqueous media. Enteric coatings based on CAP are resistant to acidic gastric fluids, but easily soluble in mildly basic medium of the intestine.
Cellacefate Bp Grade Cellulose Acetate Phthalate Ph Eur
Action and use: Enteric coating in pharmaceutical products.
Partly O-acetylated and O-phthalylated cellulose.
phthaloyl groups (C8H5O3; Mr 149.1): 30.0 per cent to 36.0 per cent (anhydrous and acid-free substance);
acetyl groups (C2H3O; Mr 43.04): 21.5 per cent to 26.0 per cent (anhydrous and acid-free substance).
Appearance: White or almost white, free-flowing powder or colourless flakes, hygroscopic.
Solubility: Practically insoluble in water, freely soluble in acetone, soluble in diethylene glycol, practically insoluble in ethanol (96 per cent) and in methylene chloride. It dissolves in dilute solutions of alkali hydroxides.
Infrared absorption spectrophotometry.
Viscosity: 45 mPas to 90 mPas, determined at 25 ± 0.2C.
Dissolve 15 g, calculated with reference to the anhydrous substance, in 85 g of a mixture of 1 part by mass of water and 249 parts by mass of acetone.
Free acid: Maximum 3.0 per cent, calculated as phthalic acid (anhydrous substance).
Water: Maximum 5.0 per cent, determined on 0.500 g.
Sulfated ash: Maximum 0.1 per cent, determined on 1.0 g.
Cellacefate USP NF Grade
Cellulose, acetate, 1,2-benzenedicarboxylate.
Cellulose acetate phthalate [9004-38-0].
Cellacefate is a reaction product of phthalic anhydride and a partial acetate ester of cellulose. It contains not less than 21.5 percent and not more than 26.0 percent of acetyl (C2H3O) groups and not less than 30.0 percent and not more than 36.0 percent of phthalyl(o-carboxybenzoyl) (C8H5O3) groups, calculated on the anhydrous, acid-free basis.
Packaging and storage: Preserve in tight containers.
Identification: Infrared Absorption.
Viscosity: Dissolve 15 g, calculated on the anhydrous basis, in 85 g of a mixture of 249 parts of anhydrous acetone and 1 part of water, by weight: the apparent viscosity is between 45 and 90 centipoises, determined at 25 ± 0.2C.
Water: not more than 5.0%.
Residue on ignition: not more than 0.1%.
Heavy metals: 0.001%.
Limit of free acid: To pass the test. Not more than 3.0%, calculated as phthalic acid, is found.
Phthalyl content: To meet the assay.
Content of acetyl: To meet the assay.
For Original Monographs of IP Indian Pharmacopoeia BP British Pharmacopoeia USP US Pharmacopoeia FCC Food Grade product, please check with the respective web-pages or books.
We manufacture and supply as under:
Cellulose acetate butyrate or Cellaburate
Cellulose Acetate Phthalate
Ethyl cellulose & it's Dispersion
Hydroxypropyl Methylcellulose HPMC
Hydroxypropyl Methycellulose Phthalate.
We also manufacture and supply as under:
Diethyl phthalate or DEP
Potassium Hydrogen Phthalate
Ambernath Mumbai, Ankleshwar Gujarat, India
TEL: (OFFICE) +912223770100, +912223726950
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Last 25 August, 2022
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Cellulose Acetate Phthalate SDS GHS, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet 07-Oct-20
Section 1: Chemical Product and Company Identification
Product Name & Other Names: CAP, Cellulose Acetate Phthalate or Cellacefate.
CAS Number: 9004-38-0
EINECS EC Code: -
Relevant uses and uses advised against (if any): Industrial Manufacturing.
Suppliers: As per letterhead.
Section 2: Hazards Identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Hazard Class and Category Code(s), Regulation (EC) No 1272/2008 (CLP)
Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
This substance is not classified as dangerous according to Directive 67/548/EEC.
Labeling Regulation as per GHS & EC 1272/2008 (CLP) & GHS
GHS Label Elements
Signal Word: None
Hazards not otherwise classified (HNOC):
May causes mild skin irritation.
May causes mild eye irritation.
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P262: Do not get in eyes, on skin, or on clothing.
P281: Use personal protective equipment as required.
P302+P352 - IF ON SKIN: Wash with plenty of soap and water.
P303+P361+P353 - IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
P304 + P340 - IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+313: If eye irritation persists get medical advice/attention.
Section 3: Composition and Information on Ingredients
Product Name/Synonyms: CAP, Cellulose Acetate Phthalate or Cellacefate.
CAS Number: 9004-38-0
Section 4: First Aid Measures
Always seek medical advice after the first aid treatment.
Skin: Rinse with water. Soap may be used. Seek Medical Aid.
Eyes: Wash eyes with plenty of water for at least 15 minutes, lifting lids occasionally. Seek Medical Aid.
Inhalation: Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Ingestion: If swallowed, induce vomiting immediately after giving two glasses of water. Never give anything by mouth to an unconscious person.
Treatment: Treat symptomatically.
Section 5: Fire and Explosion Data
Products of Combustion: Oxides of Carbon.
Fire Fighting Media and Instructions: Use water spray, alcohol-resistant foam, dry chemical, or carbon dioxide. Wear self-contained breathing apparatus for firefighting if necessary.
General: Powdered material may form explosive dust-air mixtures.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes.
Section 6: Accidental Release Measures
Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil or water sources.
Methods and materials used for containment Cleanup procedures and Storage:
Small Spill: Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to legal requirements.
Large Spill: Contain spilled material. Do not inhale dust, vapors, mist, or gas. Avoid dust formation. Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and allow to evacuate as per law.
Section 7: Handling and Storage
Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Do not leave the material container open. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like oxidizing agents, acids.
Section 8: Exposure Controls/Personal Protection
Exposure Guidelines: This product does not contain any hazardous materials with occupational exposure limits established by the region-specific regulatory bodies.
Engineering Controls: Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits. If user operations generate dust, fume, or mist, use ventilation to keep exposure to airborne contaminants below the exposure limit.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Dust deposits on floors and other surfaces may pick up moisture and cause the surfaces to become slippery and present safety hazards. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.
Section 9: Physical and Chemical Properties
Physical state and appearance: Solid off-white to white crystals powder or granules.
Odor: Not available.
Odor threshold: Not available.
pH: Not available.
Relative density: Not available.
Melting point/freezing point: Not available.
Initial boiling point and boiling range: Not available.
Flash point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility: Sparingly soluble in water.
Viscosity: Not available.
Section 10: Stability and Reactivity Data
Stability: It is stable in room temperature in closed containers under normal storage & handling.
Conditions of instability: Incompatible materials, Strong oxidizers.
Incompatibility with various substances: Avoid high temperatures, sparks, open flames, and moisture. Avoid contact with strong oxidizing agents. Avoid dust formation.
Polymerization: Will not occur.
Section 11: Toxicological Information
LD50 Oral - Rat: No data available.
Carcinogenic Effects: Not a reported carcinogen by IARC, NTP, ACGIH, OSHA.
Reproductive toxicity: No data available.
Teratogenicity: No data available.
Developmental Effects: No data available.
Section 12: Ecological Information
Toxicity to fish: No data available.
BOD5 and COD: Not available.
Persistence and degradability: Not available.
Mobility in soil: Not available.
Results of PBT and vPvB assessment: Not available.
Section 13: Disposal Considerations
Waste Disposal: Waste must be disposed of in accordance with federal, state, and local environmental control regulations.
Section 14: Transport Information
DOT (USA) & ADR/RID Europe: Not dangerous goods
IMDG: Not dangerous goods
IATA: Not dangerous goods.
Section 15: Other Regulatory Information
USA Regulations:Section 16 - Additional Information
SARA 202: Not applicable
SARA 313: Not applicable
SARA 311/312 Hazard Categories: Not applicable
California Prop 65: California No Significant Risk Level: None of the chemicals in this product are listed.
Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.