Carmellose Sodium BP Manufacturers, with SDS GHS MSDS Sheet
Supplier, Manufacturer, Exporter of Carmellose Sodium, Muby Chemicals of Mubychem Group, established in 1976, is the original manufacturers of Specialty Chemicals, Pharmaceutical Excipient, Fragrance Food & Flavor chemicals, Reagent Grade Chemicals, Shale Gas Fracturing Chemicals in India. Mubychem Group has several manufacturing facilities spread across Western India and world wide contacts and toll manufacturers. We are exporting globally to countries like USA, Canada, Europe, UAE, South Africa, Tanzania, Kenya, Egypt, Nigeria, Cameroon, Uganda, Turkey, Mexico, Brazil, Chile, Argentina, Dubai, Korea, Vietnam, Thailand, Malaysia, Indonesia, Australia, China, Germany, France, Italy, Portugal etc.
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Carmellose Sodium BP USP NF FCC Food Grade Manufacturers, with SDS GHS MSDS Sheet
Carmellose Sodium: CAS Number: 9004-32-4, EINECS EC Number: yyyyy, Molecular Formula: yyyyy, Molecular Weight: yyyyy, HS Code ---**
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SDS MSDS Sheet of Carmellose Sodium Manufacturers
Pure BP USP FCC Food Grade Suppliers
Carmellose Sodium BP Grade
Carmellose sodium (carboxymethylcellulose sodium) is the sodium salt of a partly Ocarboxymethylated cellulose. It contains not less than 6.5 per cent and not more than 10.8 per cent of sodium (Na), calculated with reference to the dried substance.
A white or almost white, granular powder, hygroscopic after drying, practically insoluble in acetone, in ethanol and in toluene. It is easily dispersed in water giving colloidal solutions.
A. To 10 ml of solution S (see Tests) add 1 ml of copper sulphate solution. A blue, cotton-like precipitate is formed.
B. Boil 5 ml of solution S for a few minutes. No precipitate is formed.
C. The solution prepared from the sulphated ash in the test for heavy metals gives the reactions of sodium.
Solution S: Sprinkle a quantity of the substance to be examined equivalent to 1.0 g of the dried substance onto 90 ml of carbon dioxide-free water at 40C to 50C stirring vigorously. Continue stirring until a colloidal solution is obtained, cool and dilute to 100 ml with carbon dioxide-free water.
Appearance of solution: Solution S is not more opalescent than reference suspension and not more intensely coloured than reference solution.
pH: The pH of solution S is 6.0 to 8.0.
Apparent viscosity: While stirring, introduce a quantity of the substance to be examined equivalent to 2.00 g of the dried substance into 50 ml of water heated to 90C. For a product of low viscosity, use if necessary, the quantity required to give the concentration indicated on the label. Allow to cool, dilute to 100.0 ml with water and stir until dissolution is complete. Determine the viscosity using a rotating viscometer at 20C and a shear rate of 10s- 1. If it is impossible to obtain a shear rate of exactly 10s- 1, use a shear rate slightly higher and a rate slightly lower and interpolate. The apparent viscosity is not less than 75 per cent and not more than 140 per cent of the value stated on the label.
Sodium glycollate: To pass the test: (0.4 per cent)
Chlorides: Dilute 2 ml of solution S to 15 ml with water R . The solution complies with the limit test for chlorides (0.25 per cent).
Heavy metals: To the residue obtained in the determination of the sulphated ash, add 1 ml of hydrochloric acid and evaporate on a water-bath. Take up the residue in 20 ml of water. 12 ml of the solution complies with limit test A for heavy metals (20 ppm).
Loss on drying: Not more than 10.0 per cent, determined on 1.000 g by drying in an oven at 105C.
Sulphated ash: 20.0 per cent to 33.3 per cent, determined on 1.0 g using a mixture of equal volumes of sulphuric acid and water and calculated with reference to the dried substance. These limits correspond to a content of 6.5 per cent to 10.8 per cent of sodium (Na).
For Original Monographs of IP Indian Pharmacopoeia BP British Pharmacopoeia USP US Pharmacopoeia FCC Food Grade product, please check with the respective web-pages or books.
We manufacture and supply as under:
Cellulose Acetate Phthalate
Ethyl cellulose & it's Dispersion
Hydroxypropyl Methylcellulose HPMC
Hydroxypropyl Methycellulose Phthalate.
Ambernath Mumbai, Ankleshwar Gujarat, India
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Last : 25 August, 2022
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Carmellose Sodium SDS, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet 07-Oct-20
Section 1: Chemical Product and Company Identification
Product Name & Other Names: Carmellose Sodium; Sodium salt of a partly O-carboxymethylated cellulose.
CAS Number: 9004-32-4
EINECS EC Code: -
Relevant uses and uses advised against (if any): Industrial use.
Suppliers: As per letterhead.
Section 2: Hazards Identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Hazard Class and Category Code(s), Regulation (EC) No 1272/2008 (CLP)
Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
This substance is not classified as dangerous according to Directive 67/548/EEC.
Labeling Regulation EC 1272/2008 (CLP) & GHS
GHS Label Elements
Signal Word: None
Hazards not otherwise classified (HNOC):
May causes mild skin irritation.
May causes mild eye irritation.
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P262: Do not get in eyes, on skin, or on clothing.
P281: Use personal protective equipment as required.
P302+P352 - IF ON SKIN: Wash with plenty of soap and water.
P304 + P340 - IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+313: If eye irritation persists get medical advice/attention.
Section 3: Composition and Information on Ingredients
Product Name & Other Names: Carmellose Sodium; Sodium salt of a partly O-carboxymethylated cellulose.
CAS Number: 9004-32-4
Section 4: First Aid Measures
Always seek medical advice after the first aid treatment.
Skin: Rinse with water. Soap may be used. Seek Medical Aid.
Eyes: Wash eyes with plenty of water for at least 15 minutes, lifting lids occasionally. Seek Medical Aid.
Inhalation: Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Ingestion: If swallowed, induce vomiting immediately after giving two glasses of water. Never give anything by mouth to an unconscious person.
Section 5: Fire and Explosion Data
Flammability of the Product: Non-flammable.
Products of Combustion: Oxides of Carbon and Sodium.
Fire Fighting Media and Instructions: Use water spray, alcohol-resistant foam, dry chemical, or carbon dioxide. Wear self-contained breathing apparatus for firefighting if necessary.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes.
Section 6: Accidental Release Measures
Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Ensure adequate ventilation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil or water sources.
Methods and materials used for containment Cleanup procedures and Storage:
Small Spill: Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to legal requirements.
Large Spill: Do not inhale vapors, mist, or gas. Avoid dust formation. Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and allow to evacuate as per law.
Section 7: Handling and Storage
Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Do not leave the material container open. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like oxidizing agents, acids.
Section 8: Exposure Controls/Personal Protection
Engineering Controls: Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits. If user operations generate dust, fume, or mist, use ventilation to keep exposure to airborne contaminants below the exposure limit.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Dust deposits on floors and other surfaces may pick up moisture and cause the surfaces to become slippery and present safety hazards. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.
Section 9: Physical and Chemical Properties
Physical state and appearance: Solid off-white powder.
Odor threshold: Not available.
pH: Not available.
Relative density: Not available.
Melting point/freezing point: Not available.
Initial boiling point and boiling range: Not available.
Flash point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility: Slightly soluble in water.
Viscosity: Not available.
Section 10: Stability and Reactivity Data
Stability: It is stable in room temperature in closed containers under normal storage & handling.
Conditions of instability: Incompatible materials, Moisture
Incompatibility with various substances: Avoid high temperatures, sparks, open flames, and moisture. Avoid contact with strong oxidizing agents and acids.
Polymerization: Will not occur.
Section 11: Toxicological Information
LD50 Oral - Rat - 27000 mg/kg
LD50 Dermal - Rabbit - > 2,000 mg/kg
Carcinogenic Effects: Not a reported carcinogen by IARC, NTP, ACGIH, OSHA.
Mutagenic Effects: Not available.
Developmental Toxicity: Not available.
Reproductive Effects: No information available.
Section 12: Ecological Information
Toxicity to fish: LC50 - Oncorhynchus mykiss (rainbow trout) - 100 - 1,000 mg/l - 96h.
Toxicity to daphnia and other aquatic invertebrates: EC50 - Daphnia (water flea) - 87.26 mg/l - 48 h.
BOD5 and COD: Not available.
Products of Biodegradation: The product itself and its products of degradation are not toxic.
Results of PBT and vPvB assessment: This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
Section 13: Disposal Considerations
Waste Disposal: Waste must be disposed of in accordance with federal, state, and local environmental control regulations.
Section 14: Transport Information
DOT USA: Not dangerous goods
IMDG: Not dangerous goods
IATA: Not dangerous goods
ADR/RID Europe: Not dangerous goods.
Section 15: Other Regulatory Information
OSHA: None of the chemicals in this product are considered highly hazardous by OSHA.
SARA 313: Not applicable.
SARA 311/312 Hazardous Categorization: Not applicable.
California Proposition 65: This product does not contain any Proposition 65 chemicals.
Section 16 - Additional Information
Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.