Calcium lactobionate USP FCC Food Grade & Pure Grade Manufacturers, with SDS GHS MSDS Sheet
Supplier, Manufacturer, Exporter of Calcium lactobionate, Muby Chemicals of Mubychem Group, established in 1976, is the original manufacturers of Specialty Chemicals, Pharmaceutical Excipient, Fragrance Food & Flavor chemicals, Reagent Grade Chemicals, Shale Gas Fracturing Chemicals in India. Mubychem Group has several manufacturing facilities spread across Western India and world wide contacts and toll manufacturers. We are exporting globally to countries like USA, Canada, Europe, UAE, South Africa, Tanzania, Kenya, Egypt, Nigeria, Cameroon, Uganda, Turkey, Mexico, Brazil, Chile, Argentina, Dubai, Korea, Vietnam, Thailand, Malaysia, Indonesia, Australia, China, Germany, France, Italy, Portugal etc.
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Calcium lactobionate: CAS Number: 110638-68-1, EINECS EC Number: 225-668-2, Molecular Formula: C24-H42-Ca-O24-2H2O, Molecular Weight: 790.68 HS Code ---**
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SDS MSDS Sheet of Calcium lactobionate Manufacturers
Spanish Lactobionato de calcio Fabricantes
Pure & USP Grade Suppliers
Calcium lactobionate is a food additive used as a stabilizer.
Calcium Lactobionate USP Grade
C24H42CaO24.2H2O -- 790.68
D-Gluconic acid, 4-O- -D-galactopyranosyl-, calcium salt (2:1), dihydrate.
Lactobionic acid, calcium salt (2:1), dihydrate.
Calcium lactobionate (1:2), dihydrate [CAS 110638-68-1].
Calcium Lactobionate contains not less than 96.0 percent and not more than 102.0 percent of C24H42CaO24.2H2O.
Packaging and storage— Preserve in well-closed containers.
A: A solution (1 in 50) responds to the tests for Calcium.
B: Infrared Absorption 197K.
C: Dissolve a quantity of it in water to obtain a test solution containing 10 mg per mL. Similarly prepare a Standard solution of USP Calcium Lactobionate RS in water containing 10 mg per mL. Apply separately 5 :L of the test solution and 5 :L of the Standard solution to a suitable thin-layer chromatographic plate coated with a 0.25-mm layer of chromatographic silica gel. Dry the plate in a current of cool air. Place the plate in a suitable chromatographic chamber lined with filter paper and previously equilibrated with a solvent system consisting of a mixture of alcohol, water, ethyl acetate, and ammonium hydroxide (50:30:10:10). Develop the chromatogram until the solvent front has moved about three-fourths of the length of the plate. Remove the plate from the chamber, and dry at 100 for 20 minutes. Allow to cool, and spray with a spray reagent prepared as follows. Dissolve 2.5 g of ammonium molybdate in about 50 mL of 2 N sulfuric acid in a 100-mL volumetric flask, add 1.0 g of ceric sulfate, swirl to dissolve, dilute with 2 N sulfuric acid to volume, and mix. Heat the plate at 110 for about 10 minutes: the principal spot obtained from the test solution corresponds in color, size, and RF value to that obtained from the Standard solution.
Specific rotation: between +22.0 and +26.5 .
pH: between 5.4 and 7.4, in a solution (1 in 20).
Halides: A 1.2-g portion tested as directed under Chloride shows no more turbidity than corresponds to 0.7 mL of 0.020 N hydrochloric acid (0.04%).
Sulfate: A 2.0-g portion dissolved in boiling water shows no more sulfate than corresponds to 1 mL of 0.020 N sulfuric acid (0.05%).
Heavy metals: Mix 1 g with 4 mL of 1.2 N hydrochloric acid, add water to make 25 mL, warm gently until dissolved, and cool to room temperature: the limit is 0.002%.
Reducing substances: Transfer 1.0 g to a 250-mL conical flask, dissolve in 20 mL of water, and add 25 mL of alkaline cupric citrate. Cover the flask, boil gently for 5 minutes, accurately timed, and cool rapidly to room temperature. Add 25 mL of 0.6 N acetic acid, 10.0 mL of 0.1 N iodine VS, and 10 mL of 3 N hydrochloric acid, and titrate with 0.1 N sodium thiosulfate VS, adding 3 mL of starch as the endpoint is approached. Perform a blank determination, omitting the specimen, and note the difference in volumes required. Each mL of the difference in volume of 0.1 N sodium thiosulfate consumed is equivalent to 2.7 mg of reducing substances (as dextrose): the limit is 1.0%.
Dissolve about 0.8 g of Calcium Lactobionate, accurately weighed, in a mixture of water and 3 N hydrochloric acid (150:2). While stirring with a magnetic stirrer, add about 15 mL of 0.05 M edetate disodium VS from a 50-mL buret. Add 15 mL of 1 N sodium hydroxide and 300 mg of hydroxy naphthol blue, and continue the titration to a blue endpoint. Each mL of 0.05 M edetate disodium is equivalent to 39.53 mg of C24H42CaO24.2H2O.
Calcium Lactobionate FCC Food Grade
C24H42CaO24 Formula wt, anhydrous 754.66
Calcium Lactobionate occurs as a white to cream-colored, free-flowing powder. It readily forms double salts, such as the chloride, bromide, and gluconate. It is anhydrous when obtained by spray-drying, or the dihydrate when obtained by crystallization. It is freely soluble in water, but insoluble in alcohol and in ether. It decomposes at about 120°. The pH of a 1:10 aqueous solution is between 6.5 and 7.5.
Function: Firming agent in dry pudding mixes; nutrient.
Labeling: Indicate whether the product has been obtained through spray-drying or from crystallization.
A. The infrared absorption spectrum of a potassium bromide dispersion of the sample, previously dried at 105C for 8 h, exhibits relative maxima at the same wavelengths as those of a similar preparation of USP Calcium Lactobionate Reference Standard.
B. A sample gives positive tests for Calcium.
Calcium Content: Not less than 5.05% and not more than 5.55% of calcium (Ca), calculated on the dried basis.
Halides: Not more than 0.04%.
Lead: Not more than 2 mg/kg.
Loss on Drying: Not more than 8.0%.
Optical (Specific) Rotation [α]D20C: Between +23° and +25°.
Reducing Substances: Not more than 1.0%.
Sulfate: Not more than 0.7%.
For Original Monographs of IP Indian Pharmacopoeia BP British Pharmacopoeia USP US Pharmacopoeia FCC Food Grade product, please check with the respective web-pages or books.
We manufacture and supply as under:
Calcium Alpha Ketoglutarate
Calcium Polystyrene Sulfonate
Calcium Sucrose Phosphate
We also manufacture and supply as under:
Calcium Bromo Lactobionate.
Ambernath Mumbai, Ankleshwar Gujarat, India
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Last : 25 August, 2022
List of All the IP, BP, EP, Ph Eur, USP NF, JP, FCC Food, Analytical Reagent Grades of Chemicals Best Seller Fast Moving IP, BP, EP, Ph Eur, USP NF, JP, FCC Food, Analytical Reagent Grades of Chemicals Ex-stock Items Aluminum Chloride Hexahydrate Aluminium Potassium Sulphate Ammonium Bicarbonate Ammonium Carbonate Ammonium Chloride Ammonium Persulfate Borax; Sodium Borate Boric Acid Calcium Chloride Calcium Saccharate Calcium Sulfate Carbamide Peroxide Chromic Chloride Cupric or Copper Chloride Ferric Chloride Hexahydrate Fumaric Acid Glacial Acetic Acid Lactobionic Acid Magnesium Chloride Magnesium Sulfate Manganese Chloride Manganese Sulfate Potassium Bromide Potassium Chloride Potassium Hydroxide Pellets Potassium Nitrate Propylene Carbonate Potassium Monopersulfate Selenious acid Sodium Acetate Sodium Bromate Sodium Diacetate Sodium Formaldehyde Bisulfite Sodium Lactobionate Sodium Thiosulfate Zinc Chloride
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Calcium Lactobionate SDS, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet
Section 1: Chemical Product and Identification
Product Name & Other Names: Calcium Lactobionate or Lactobionic acid calcium salt
EINECS EC-No.: 225-668-2
Chemical Formula: C24H42CaO24-2H2O
Molecular Weight: 790.68
Relevant uses and uses advised against (if any): Laboratory and Industrial Manufacturing.
SUPPLIER: As per letterhead.
Section 2: Hazards Identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008
Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
This substance is not classified as dangerous according to Directive 67/548/EEC.
Labeling according to GHS & Regulation (EC) No 1272/2008
GHS Label Elements
Signal Word: None
Not considered hazardous by the OSHA Hazard Communication Standard (29 CFR 1910.1200)
Hazards not otherwise classified (HNOC):
May causes mild skin irritation.
May Causes mild eye irritation.
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P302+P352 - IF ON SKIN: Wash with plenty of soap and water.
P303+P361+P353 - IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
P304 + P340 - IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+313: If eye irritation persists get medical advice/attention.
Section 3: Composition and Information on Ingredients
Product Name & Other Names: Calcium Lactobionate or Lactobionic acid calcium salt
EINECS EC-No.: 225-668-2
Section 4: First Aid Measures
Always seek medical attention after first aid measures are provided.
Eye Contact: In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Get medical attention.
Skin Contact: In case of contact, immediately flush skin with plenty of water. Cover the irritated skin with an emollient. Thoroughly clean shoes and clothes before reuse. Get medical attention.
Inhalation: If Calcium Lactobionate is inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.
Ingestion: Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. If large quantities of this material are swallowed, call a physician immediately.
Section 5: Fire and Explosion Data
Flammability of the Product: It may be combustible at high temperature.
Auto-Ignition Temperature: Not available.
Products of Combustion: Some metallic oxides CO CO2 and fumes.
Fire Hazards in Presence of Various Substances: Slightly flammable in presence of heat. Non-flammable in presence of shocks.
Explosion Hazards in Presence of Various Substances: Slightly explosive in presence of open flames and sparks. Non-explosive in presence of shocks.
Fire Fighting Media and Instructions:
Small Fire: Use DRY chemical powder.
Large Fire: Use water spray, fog, or foam. Avoid water jet.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes.
Section 6: Accidental Release Measures
Personal precautions, protective equipment, and emergency procedures: Ventilate area of leak or spill. Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment Cleanup procedures and Storage:
Small Spill: Avoid dust formation. Avoid breathing vapors, mist, or gas. Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to legal authority requirements.
Large Spill: Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g. sand, earth, diatomaceous earth, vermiculite). Vacuum or sweep-up and remove to an approved disposal container. Finish cleaning by spreading water on the contaminated surface and allow to drain as per law.
Section 7: Handling and Storage
Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like strong oxidizing agents.
Section 8: Exposure Controls/Personal Protection
Exposure Limits: Not established.
Engineering Controls: Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits. If user operations generate dust, fume, or mist, use ventilation to keep exposure to airborne contaminants below the exposure limit.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Dust deposits on floors and other surfaces may pick up moisture and cause the surfaces to become slippery and present safety hazards. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.
Section 9: Physical and Chemical Properties
Physical state and appearance: White solid. (Powdered solid. Crystalline powder.)
Odor threshold: Not available.
pH: Not available.
Relative density: Not available.
Melting Point: 190C
Initial boiling point and boiling range: Not available.
Flash point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility: Insoluble in cold water, hot water. Almost insoluble in ethanol.
Viscosity: Not available.
Chemical Formula: C24H42CaO24-2H2O
Molecular Weight: 790.68
Section 10: Stability and Reactivity Data
Stability: It is stable.
Conditions of Instability: Excessive heat, dust generation
Incompatibility with various substances: Oxidizing Agents, heat and sunlight.
Special Remarks on Reactivity: Releases water of crystallization when heated and decomposes.
Hazardous decomposition products formed under fire conditions: Carbon oxides, Calcium oxide.
Polymerization: Will not occur.
Section 11: Toxicological Information
Toxicity to Animals: Not available.
Carcinogenicity: No component of this product present at levels greater than or equal to 0.1% is identified as probable or confirmed human carcinogen by IARC, ACGIH, OSHA and NTP.
Mutagenic Effects: Not available.
Teratogenic Effects: Not available.
Environmental Toxicity: Not available.
Section 12: Ecological Information
Ecotoxicity: Not available.
Products of Biodegradation: Possibly hazardous short-term degradation products are not likely. However, long term degradation products may arise.
Toxicity of the Products of Biodegradation: The product itself and its products of degradation are not toxic.
Results of PBT and vPvB assessment: This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bio accumulative (vPvB) at levels of 0.1% or higher.
Section 13: Disposal Considerations
Waste Disposal: Waste must be disposed of in accordance legal regulations.
Section 14: Transport Information
DOT USA: Not dangerous goods
ADR/RID Europe: Not dangerous goods
TDG/IMDG: Not dangerous goods
IATA: Not dangerous goods
Section 15: Other Regulatory Information
USA:Section 16 - Additional Information
Section 313 of Title III of the Superfund Amendments and Reauthorization Act of 1986 (SARA): This product does not contain any chemicals which are subject to the reporting requirements of the Act and Title 40 of the Code of Federal Regulations, Part 372.
SARA 311/312 Hazard Categories: Not applicable.
CWA (Clean Water Act): This product does not contain any substances regulated as pollutants pursuant to the Clean Water Act (40 CFR 122.21 and 40 CFR 122.42).
California Proposition 65: This product does not contain any Proposition 65 chemicals.
DISCLAIMER: The information and recommendations set forth herein (hereinafter "Information") are presented in good faith and believed correct as of the date hereof. It is compiled from various sources and it is not necessarily all inclusive nor fully adequate in every circumstance. In addition, these suggestions should not be confused with nor followed in violation of applicable laws, regulations, rules or insurance requirements applicable. This MSDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. Individuals receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose.