Calcium Glycerophosphate BP Ph Eur USP FCC Food Grade Manufacturers, with SDS GHS MSDS Sheet

Supplier, Manufacturer, Exporter of Calcium Glycerophosphate, Muby Chemicals of Mubychem Group, established in 1976, is the original manufacturers of Specialty Chemicals, Pharmaceutical Excipient, Fragrance Food & Flavor chemicals, Reagent Grade Chemicals, Shale Gas Fracturing Chemicals in India. Mubychem Group has several manufacturing facilities spread across Western India and world wide contacts and toll manufacturers. We are exporting globally to countries like USA, Canada, Europe, UAE, South Africa, Tanzania, Kenya, Egypt, Nigeria, Cameroon, Uganda, Turkey, Mexico, Brazil, Chile, Argentina, Dubai, Korea, Vietnam, Thailand, Malaysia, Indonesia, Australia, China, Germany, France, Italy, Portugal etc.

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Calcium Glycerophosphate: CAS Number: 27214-00-2, EINECS EC Number: 248-328-5, Molecular Formula: C3H7CaO6P, Molecular Weight: 210.13 HS Code ---**

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SDS MSDS Sheet of Calcium Glycerophosphate Manufacturers

Spanish Fabricantes de glicerofosfato de calcio

Calcium Glycerophosphate
Pure BP Ph Eur USP Grade Suppliers
Calcium Glycerophosphate

Calcium glycerophosphate is a mineral composed of calcium and phosphorous. Bone and teeth are largely comprised of calcium phosphate and its derivatives. However, the bioavailability of calcium salts and other calcium-based compounds has presented a challenge in the past. Calcium glycerophosphate is a relatively new dietary supplement that appears to offer health benefits, as it is more readily absorbed.

Calcium glycerophosphate is available as  a supplement. Studies have found that calcium glycerophosphate can significantly reduce the urge to urinate, as well as minimize discomfort experienced after consuming highly acidic foods and beverages.

Calcium Glycerophosphate USP Dietary Supplement Grade:
C3H7CaO6P --- 210.14
1,2,3-Propanetriol, mono(dihydrogen phosphate) calcium salt (1:1);    
Calcium glycerophosphate CAS 27214-00-2.

DEFINITION
Calcium Glycerophosphate is a mixture, in variable proportions, of calcium (RS)-2,3-dihydroxypropyl phosphate and calcium 2-hydroxy-1-(hydroxymethyl)ethyl phosphate, which may be hydrated. Calcium Glycerophosphate contains NLT 18.6% and NMT 19.4% of calcium (Ca), calculated on the dried basis.

IDENTIFICATION
A.
Analysis: Ignite 0.1 g in a crucible. Take up the residue with 5 mL of nitric acid, heat on a water bath for 1 min, and filter. Mix 1 mL of the filtrate with 2 mL of ammonium molybdate.
Acceptance criteria: A yellow color develops.
B.
Analysis: Dissolve 20 mg of the substance being examined in 5 mL of 5 M acetic acid and add 0.5 mL of potassium ferrocyanide solution (53 mg/mL). The resulting solution remains clear. To the clear solution, add 50 mg of ammonium chloride.
Acceptance criteria: A white crystalline precipitate is produced.

Lead: NMT 4 ppm.
Iron: To pass the test.
Acceptance criteria: NMT 20 ppm.
Limit of Chloride: To pass the test.
Acceptance criteria: NMT 0.04%
Limit of Sulfate: To pass the test.
Acceptance criteria: NMT 0.2%
Limit of Arsenic: To pass the test.
Acceptance criteria: NMT 3 ppm.
Limit of Phosphates:
Acceptance criteria: NMT 0.04%
Citric Acid: To pass the test.
Glycerol and Alcohol-soluble Substances: To pass the test.
Appearance of Solution: To pass the test.
Acidity or Alkalinity: To pass the test.
Loss on Drying : Dry a sample at 150C for 4 h: it loses NMT 12.0% of its weight.

Calcium Glycerophosphate BP (also Ph Eur)
Ph Eur
C3H7CaO6P -- 210.1 -- CAS 27214-00-2
Action and use: Excipient.

DEFINITION
Mixture in variable proportions of the calcium salt of 2,3-dihydroxypropyl phosphate and of 2-hydroxy-1-(hydroxymethyl)ethyl phosphate which may be hydrated.
Content: 18.6 per cent to 19.4 per cent of Ca (dried substance).

CHARACTERS
Appearance: White or almost white powder, hygroscopic.
Solubility: Sparingly soluble in water, practically insoluble in ethanol (96 per cent).

IDENTIFICATION
A. Mix 1 g with 1 g of potassium hydrogen sulphate in a test tube fitted with a glass tube. Heat strongly and direct the white vapour towards a piece of filter paper impregnated with a freshly prepared 10 g/l solution of sodium nitroprusside. The filter paper develops a blue colour in contact with piperidine.
B. Ignite 0.1 g in a crucible. Take up the residue with 5 ml of nitric acid and heat on a water-bath for 1 min. Filter. The filtrate gives reaction of phosphates.
C. It gives reaction of calcium.

TESTS
Solution S: Dissolve 1.5 g at room temperature in carbon dioxide-free water prepared from distilled water and dilute to 150 ml with the same solvent.
Appearance of solution: Solution S is not more opalescent than reference suspension.
Acidity or alkalinity: To 100 ml of solution S add 0.1 ml of phenolphthalein solution. Not more than 1.5 ml of 0.1 M hydrochloric acid or 0.5 ml of 0.1 M sodium hydroxide is required to change the colour of the indicator.
Citric acid: Shake 5.0 g with 20 ml of carbon dioxide-free water and filter. To the filtrate add 0.15 ml of sulphuric acid and filter again. To the filtrate add 5 ml of mercuric sulphate solution and heat to boiling. Add 0.5 ml of a 3.2 g/l solution of potassium permanganate and again heat to boiling. No precipitate is formed.
Glycerol and ethanol (96 per cent)-soluble substances: Maximum 0.5 per cent. Shake 1.000 g with 25 ml of ethanol (96 per cent) for 1 min. Filter. Evaporate the filtrate on a water-bath and dry the residue at 70 °C for 1 h. The residue weighs a maximum of 5 mg.
Chlorides: Maximum 500 ppm.
Phosphates: Maximum 400 ppm.
Sulphates: Maximum 0.1 per cent, determined on solution S.
Arsenic: Maximum 3 ppm.
Iron: Maximum 50 ppm, determined on 0.20 g.
Heavy metals: Maximum 20 ppm.
Loss on drying: Maximum 12.0 per cent, determined on 1.000 g by drying in an oven at 150 °C for 4 h.

ASSAY
Dissolve 0.200 g in water. Carry out the complexometric titration of calcium. 1 ml of 0.1 M sodium edetate is equivalent to 4.008 mg of Ca.


Calcium Glycerophosphate FCC Food Grade
C3H7CaO6P Formula weight 210.14
CAS 27214-00-2

DESCRIPTION
Calcium Glycerophosphate occurs as a fine, white powder. It is somewhat hygroscopic. One gram dissolves in about 50 mL of water at 25C. It is more soluble in water at a lower temperature, and citric acid increases its solubility in water. It is insoluble in alcohol.
Function: Nutrient.

REQUIREMENTS
Identification: A saturated sample solution gives positive tests for Calcium.
Assay: Not less than 98.0% and not more than 100.5% of C3H7CaO6P, after drying.
Alkalinity: Passes test.
Lead: Not more than 4 mg/kg.
Loss on Drying: Not more than 12.0%.

For Original Monographs of IP Indian Pharmacopoeia BP British Pharmacopoeia USP US Pharmacopoeia FCC Food Grade product, please check with the respective web-pages or books.

We manufacture and supply as under:

Calcium Alpha Ketoglutarate

Calcium Arginate

Calcium Caprylate

Calcium Gluconate

Calcium Glycerophosphate

Calcium Lactobionate

Calcium Levulinate

Calcium Polystyrene Sulfonate

Calcium L-threonate.

We also manufacture and supply as under:

Calcium Glycerophosphate

Copper Glycerophosphate

Ferric Glycerophosphate

Magnesium Glycerophosphate

Manganese Glycerophosphate

Potassium Glycerophosphate

Sodium Glycerophosphate

Zinc Glycerophosphate

Glycerophosphoric Acid.

Manufacturers:

MUBY CHEMICALS
Ambernath Mumbai, Ankleshwar Gujarat, India
TEL: (OFFICE) +912223770100, +912223726950
Current Date Time in India GMT+5:30

e-mail: info@mubychem.com

USA, Canada, Mexico and other American
neighbouring buyers may
e-mail: us@mubychem.com
Call toll-free 1-844-682-9243 (1-844-MUBYCHEM)

Manufacturers india
Copyright and Usual Disclaimer is Applicable.
Last : 25 August, 2022

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Calcium Glycerophosphate SDS, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet
05-Oct-20

1. Product Identification

Product Name & Other Names: Calcium Glycerophosphate or Glycerol phosphate calcium salt.
CAS No.: 27214-00-2
EINECS EC Number: 248-328-5
Molecular Weight: 210.13
Chemical Formula: C3H7CaO6P
Relevant uses and uses advised against (if any): Laboratory and Industrial Manufacturing Use.
SUPPLIER: As per letterhead.

2. Hazards Identification

GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008

Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
This substance is not classified as dangerous according to Directive 67/548/EEC.

Labeling according to GHS & Regulation (EC) No 1272/2008

GHS Label Elements
NONE

Signal Words: None

Hazards not otherwise classified (HNOC):
May cause mild eye irritation.
May cause mild skin irritation.

Precautionary statements:
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P262: Do not get in eyes, on skin, or on clothing.
P281: Use personal protective equipment as required.
P302+P352 - IF ON SKIN: Wash with plenty of soap and water.
P303+P361+P353 - IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
P304 + P340 - IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+313: If eye irritation persists get medical advice/attention.

3. Composition/Information on Ingredients

Product Name & Other Names: Calcium Glycerophosphate or Glycerol phosphate calcium salt.
CAS No.: 27214-00-2
EINECS EC Number: 248-328-5

4. First Aid Measures

Always seek medical advice after the first aid treatment.

Inhalation: If  inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.
Ingestion:
Not expected to require first aid measures. If large amounts were swallowed, give water to drink and get medical advice.
Skin Contact: Not expected to require first aid measures. Wash exposed area with soap and water. Get medical advice if irritation develops.
Eye Contact: Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Get medical attention if irritation occurs.

5. Fire Fighting Measures

Fire: It is not considered to be a fire hazard.
Explosion: Not considered to be an explosion hazard.
Fire Extinguishing Media: Use any means suitable for extinguishing surrounding fire.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes.

6. Accidental Release Measures

Personal precautions, protective equipment, and emergency procedures: Ventilate area of leak or spill. Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment Cleanup procedures and Storage:
Small Spill: Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to local and regional authority requirements.
Large Spill: Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g. sand, earth, diatomaceous earth, vermiculite). Vacuum or sweep-up and remove to an approved disposal container. Finish cleaning by spreading water on the contaminated surface and allow to drain as per law.

7. Handling and Storage

Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. In case of insufficient ventilation, wear suitable respiratory equipment. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like strong oxidizing agents.

8. Exposure Controls/Personal Protection

Airborne Exposure Limits: None established.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator (NIOSH type N95 or better filters) may be worn. If oil particles (e.g. lubricants, cutting fluids, glycerin, etc.) are present, use a NIOSH type R or P filter. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator. WARNING: Air-purifying respirators do not protect workers in oxygen-deficient atmospheres.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Dust deposits on floors and other surfaces may pick up moisture and cause the surfaces to become slippery and present safety hazards. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.

9. Physical and Chemical Properties

Appearance: White solid or crystals or powder.
Odor: Odorless.
Odor threshold: Not available.
pH: about 8.
Relative density: Not available.
Boiling Point: Decomposes.
Melting Point: Decomposes at red heat.
Flash point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility: Soluble in water.
Viscosity: Not available.
Molecular Weight: 210.13
Chemical Formula: C3H7CaO6P

10. Stability and Reactivity

Stability:  It is stable under ordinary conditions of use and storage.
Hazardous Decomposition Products: Carbon oxides, Oxides of phosphorus, Calcium oxide.
Hazardous Polymerization: Will not occur.
Incompatibilities: Oxidizing agents and Heat.
Conditions to Avoid: Excessive dust generation.

11. Toxicological Information

Acute toxicity: LD50 (oral, Rat): >5000 mg/kg.
Carcinogenicity: No component of this product present at levels greater than or equal to 0.1% is identified as possible or confirmed human carcinogen by IARC, ACGIH, OSHA and NTP.
Mutagenic Effects: Not available.
Teratogenic Effects: Not available.
Developmental Toxicity: Not available.

12. Ecological Information

Environmental Toxicity: Not much found.
Persistence and Degradability: Unlikely to persist due to water solubility.
Mobility: Likely to be mobile due to water solubility.
Bioaccumulation/ Accumulation: No information available.
Results of PBT and vPvB assessment: No data available for assessment.

13. Disposal Considerations

Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. Processing use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose of container and unused material in accordance with federal, state, and local requirements.

14. Transport Information

DOT USA & ADR/RID Europe: Not dangerous goods.
TDG/IMDG: Not dangerous goods
IATA: Not dangerous goods.

15. Regulatory Information

USA:
SARA 311/312 Hazards
: None.
California Proposition 65: Not listed.

Section 16 - Additional Information

DISCLAIMER: The information and recommendations set forth herein (hereinafter "Information") are presented in good faith and believed correct as of the date hereof. It is compiled from various sources and it is not necessarily all inclusive nor fully adequate in every circumstance. In addition, these suggestions should not be confused with nor followed in violation of applicable laws, regulations, rules or insurance requirements applicable. This MSDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. Individuals receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose.