Butylparaben or Butyl Hydroxybenzoate, Butyl Paraben BP USP NF Manufacturers, with SDS GHS MSDS Sheet

Supplier, Manufacturer, Exporter of Butyl Paraben or Butylparaben, Muby Chemicals of Mubychem Group, established in 1976, is the original manufacturers of Specialty Chemicals, Pharmaceutical Excipient, Fragrance Food & Flavor chemicals, Reagent Grade Chemicals, Shale Gas Fracturing Chemicals in India. Mubychem Group has several manufacturing facilities spread across Western India and world wide contacts and toll manufacturers. We are exporting globally to countries like USA, Canada, Europe, UAE, South Africa, Tanzania, Kenya, Egypt, Nigeria, Cameroon, Uganda, Turkey, Mexico, Brazil, Chile, Argentina, Dubai, Korea, Vietnam, Thailand, Malaysia, Indonesia, Australia, China, Germany, France, Italy, Portugal etc.

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Butylparaben, Butyl Hydroxybenzoate, Butyl Paraben: CAS Number: 94-26-8, EINECS EC Number: 202-318-7, Molecular Formula: C11H14O3, Molecular Weight: 194.23, HS Code ---**

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For SDS MSDS Sheet Click
SDS MSDS Sheet of Butyl Paraben Manufacturers

Butyl Paraben
Butylparaben, Butyl Hydroxybenzoate Pure BP USP NF Suppliers
Butyl paraben

We supply several preservatives like 4-Hydroxybenzoic Acid, Sodium Benzoate, Methyl Paraben, Ethyl Paraben, Propyl Paraben, Butyl Paraben, Heptyl Paraben, Sodium Methyl Paraben, Sodium Ethyl Paraben, Sodium Propyl Paraben, Sodium Butyl Paraben, Potassium Sorbate, Sodium diacetate, etc.

Parabens are a class of widely used preservatives in cosmetic and pharmaceutical products. Chemically, they are a series of parahydroxybenzoates or esters of parahydroxybenzoic acid (also known as 4-hydroxybenzoic acid). Parabens are effective preservatives in many types of formulas. These compounds, and their salts, are used primarily for their bactericidal and fungicidal properties. They are found in shampoos, commercial moisturizers, shaving gels, personal lubricants, topical/parenteral pharmaceuticals, suntan products, makeup, and toothpaste. They are also used as food additives. Parabens are active against a broad spectrum of microorganisms.

Parabens are esters of para-hydroxybenzoic acid, from which the name is derived. Common parabens include methylparaben (E number E218), ethylparaben (E214), propylparaben (E216), butylparaben and heptylparaben (E209). Less common parabens include isobutylparaben, isopropylparaben, benzylparaben and their sodium salts. All commercially used parabens are synthetically produced, although some are identical to those found in nature. They are produced by the esterification of para-hydroxybenzoic acid with the appropriate alcohol, such as methanol, ethanol, or n-propanol.

Butylparaben, or butyl p-hydroxybenzoate, is an organic compound with the formula C4H9O2CC6H4OH. It is a white solid that is soluble in organic solvents. It has proven to be a highly successful antimicrobial preservative in cosmetics. It is also used in medication suspensions, and as a flavoring additive in food. Members of the paraben family are found in fruit and vegetable products, such as barley, flax seed, and grapes. Butylparaben is one of the most common bactericidal/fungicidal additives in cosmetics. The popularity of butylparaben in these products is due to its low toxicity in humans and its effective antimicrobial properties, in particular those against mold and yeast.

Butylparaben USP NF Grade
C11H14O3 194.23
Benzoic acid, 4-hydroxy-, butyl ester.
Butyl p-hydroxybenzoate [94-26-8].

Butylparaben contains not less than 98.0 percent and not more than 102.0 percent of C11H14O3.

Identification:
A: Infrared Absorption 197M .
B: Melting range: between 68C and 71C.

Color of solution: Dissolve 1 g in alcohol, dilute with alcohol to 10 mL, and mix (Butylparaben solution). This solution is clear and not more intensely colored than alcohol or a solution prepared immediately before use by mixing 2.4 mL of ferric chloride CS, 1.0 mL of cobaltous chloride, and 0.4 mL of cupric sulfate CS with 0.3 N hydrochloric acid to make 10 mL, and diluting 5 mL of this solution with 0.3 N hydrochloric acid to make 100 mL. Make the comparison by viewing the solutions downward in matched color-comparison tubes against a white surface.
Acidity: To 2 mL of Butylparaben solution prepared in the Color of solution test, add 3 mL of alcohol, 5 mL of carbon dioxide-free water, and 0.1 mL of bromocresol green, and titrate with 0.10 N sodium hydroxide: not more than 0.1 mL is required to produce a blue color.
Residue on ignition: not more than 0.1%, determined on 1.0 g.
Related substances: To pass the test
Assay: To about 1.000 g of Butylparaben, accurately weighed, add 20.0 mL of 1 N sodium hydroxide, and heat at about 70C for 1 hour. Cool rapidly in an ice bath. Carry out the titration on the solutions at room temperature. Titrate the excess sodium hydroxide with 1 N sulfuric acid, continuing the titration until the second point of inflection and determining the endpoint. Perform a blank determination. Each mL of 1 N sodium hydroxide is equivalent to 194.2 mg of C11H14O3.


Butyl Hydroxybenzoate BP Grade
Butylparaben
Butyl Parahydroxybenzoate, Ph Eur

C11H14O3 --- 194.2 --- 94-26-8
Action and use: Excipient.

DEFINITION
Butyl 4-hydroxybenzoate.
Content: 98.0 per cent to 102.0 per cent.

CHARACTERS
Appearance: White or almost white, crystalline powder or colourless crystals.
Solubility: Very slightly soluble in water, freely soluble in alcohol and in methanol.

IDENTIFICATION
First identificationı A, B.
Second identificationı A, C, D.
A. Melting point 68C to 71C.
B. Infrared absorption spectrophotometry. Comparisonı butyl parahydroxybenzoate CRS.
C. Examine the chromatograms obtained in the test for related substances.
Results: The principal spot in the chromatogram obtained with test solution (b) is similar in position and size to the principal spot in the chromatogram obtained with reference solution (b).
D. To about 10 mg in a test-tube add 1 ml of sodium carbonate solution, boil for 30 s and cool (solution A). To a further 10 mg in a similar test-tube add 1 ml of sodium carbonate solution; the substance partly dissolves (solution B). Add at the same time to solution A and solution B 5 ml of aminopyrazolone solution and 1 ml of potassium ferricyanide solution and mix. Solution B is yellow to orange-brown. Solution A is orange to red, the colour being clearly more intense than any similar colour which may be obtained with solution B.

TESTS
Solution S: Dissolve 1.0 g in alcohol and dilute to 10 ml with the same solvent.
Appearance of solution: Solution S is clear and not more intensely coloured than reference solution.
Acidity: To 2 ml of solution S add 3 ml of alcohol, 5 ml of carbon dioxide-free water and 0.1 ml of bromocresol green solution. Not more than 0.1 ml of 0.1 M sodium hydroxide is required to change the colour of the indicator to blue.
Related substances: Thin-layer chromatography to pass the test (0.5 per cent).
Sulphated ash: Maximum 0.1 per cent, determined on 1.0 g.

ASSAY
To 1.000 g add 20.0 ml of 1 M sodium hydroxide. Heat at about 70C for 1 h. Cool rapidly in an ice bath. Prepare a blank in the same manner. Carry out the titration on the solutions at room temperature. Titrate the excess sodium hydroxide with 0.5 M sulphuric acid , continuing the titration until the second point of inflexion and determining the end-point potentiometrically. 1 ml of 1 M sodium hydroxide is equivalent to 194.2 mg of C11H14O3.

IMPURITIES
A. R = H: 4-hydroxybenzoic acid,
B. R = CH3: methyl 4-hydroxybenzoate,
C. R = CH2-CH3: ethyl 4-hydroxybenzoate,
D. R = CH2-CH2-CH3: propyl 4-hydroxybenzoate.

For Original Monographs of IP Indian Pharmacopoeia BP British Pharmacopoeia USP US Pharmacopoeia FCC Food Grade product, please check with the respective web-pages or books.

Manufacturers:

MUBY CHEMICALS
Ambernath Mumbai, Ankleshwar Gujarat, India
TEL: (OFFICE) +912223770100, +912223726950
Current Date Time in India GMT+5:30

e-mail: info@mubychem.com

USA, Canada, Mexico and other American
neighbouring buyers may
e-mail: us@mubychem.com
Call toll-free 1-844-682-9243 (1-844-MUBYCHEM)

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Last 25 August, 2022

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Butyl Paraben or Butyl 4-Hydroxybenzoate SDS GHS, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet
04-Oct-20

Section 1: Chemical Product and Company Identification

Product Name & Other Names: Butyl Paraben or Butyl 4-Hydroxybenzoate.
CAS Number
: 94-26-8
EINECS EC Code: 202-318-7
Molecular Formula: C11H14O3
Molecular Weight: 194.23
Relevant uses and uses advised against (if any): Industrial Manufacturing.
Suppliers: As per letterhead.

Section 2: Hazards Identification

GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Hazard Class and Category Code(s), Regulation (EC) No 1272/2008 (CLP)

Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
This substance is not classified as dangerous according to Directive 67/548/EEC.

Labeling Regulation as per GHS & EC 1272/2008 (CLP) & GHS

GHS Label Elements
NONE

Signal Word: None

Hazards not otherwise classified (HNOC):
May causes mild skin irritation.
May causes mild eye irritation.

Precautionary statements:
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P262: Do not get in eyes, on skin, or on clothing.
P281: Use personal protective equipment as required.
P302+P352 - IF ON SKIN: Wash with plenty of soap and water.
P303+P361+P353 - IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
P304 + P340 - IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+313: If eye irritation persists get medical advice/attention.

Section 3: Composition and Information on Ingredients

Product Name & Other Names: Butyl Paraben or Butyl 4-Hydroxybenzoate.
CAS Number
: 94-26-8
EINECS EC Code: 202-318-7

Section 4: First Aid Measures

Always seek medical advice after the first aid treatment.

Skin: Rinse with water. Soap may be used. Seek Medical Aid.
Eyes: Wash eyes with plenty of water for at least 15 minutes, lifting lids occasionally. Seek Medical Aid.
Inhalation: Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Ingestion: If swallowed, induce vomiting immediately after giving two glasses of water. Never give anything by mouth to an unconscious person.

Section 5: Fire and Explosion Data

Flammability of the Product: May be combustible at high temperature. It may form combustible dust concentrations in air. Slightly flammable to flammable in presence of heat.
Products of Combustion: Oxides of Carbon.
Fire Fighting Media and Instructions: Use alcohol-resistant foam, dry chemical, or carbon dioxide. Use extinguishing measures that are appropriate to local circumstances and the surrounding environment. Wear self-contained breathing apparatus for firefighting if necessary. Avoid water spray. Use of heavy stream of water may spread fire.

Section 6: Accidental Release Measures

Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil or water sources.
Methods and materials used for containment Cleanup procedures and Storage: Cover with an inert, non-combustible absorbent material, (e.g. sand, earth, diatomaceous earth, vermiculite). Vacuum or sweep-up and remove to an approved disposal container.
Small Spill: Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to legal requirements.
Large Spill: Contain spilled material. Do not inhale vapors, mist, or gas. Avoid dust formation. Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and allow to evacuate through the sanitary system. Be careful that the product is not present at a concentration level above TLV.

Section 7: Handling and Storage

Precautions for safe handling: Avoid formation of dust and aerosols. Do not breathe dust. Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Do not leave the material container open. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like oxidizing agents, acids, and bases. Keep away from heat/sparks/open flames/hot surfaces. – No smoking. Protect from moisture. Protect from sunlight.

Section 8: Exposure Controls/Personal Protection

Exposure Guidelines: This product does not contain any hazardous materials with occupational exposure limits established by the region-specific regulatory bodies.
Engineering Controls: Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits. If user operations generate dust, fume, or mist, use ventilation to keep exposure to airborne contaminants below the exposure limit.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Dust deposits on floors and other surfaces may pick up moisture and cause the surfaces to become slippery and present safety hazards. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.

Section 9: Physical and Chemical Properties

Physical state and appearance: Solid off-white to white crystals powder or granules.
Odor: Characteristic.
Odor threshold: Not available.
pH: Not available.
Relative density: 1.28
Melting point/freezing point: 68C - 72C
Initial boiling point and boiling range: 156C - 157C
Auto-ignition Temperature: 495C
Flash point: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility: Very slightly soluble in water.
Viscosity: Not available.
Molecular Formula: C11H14O3
Molecular Weight: 194.23

Section 10: Stability and Reactivity Data

Stability: It is stable at in closed containers under normal storage & handling.
Conditions of instability: Incompatible materials.
Incompatibility with various substances: Avoid high temperatures, sparks, open flames, and direct sunlight. Avoid contact with strong oxidizing agents, acid, and bases.
Polymerization: Will not occur.

Section 11: Toxicological Information

LD50 Oral - Mouse: > 5000 mg/kg
LD50 Dermal - Rabbit: > 2.000 mg/kg
Carcinogenic Effects: Not a reported carcinogen by IARC, NTP, ACGIH, OSHA.
Reproductive toxicity: No data available.
Teratogenicity: No data available.

Section 12: Ecological Information

Toxicity to fish: Not available.
Toxicity to daphnia and other aquatic invertebrates: Not available.
Products of Biodegradation: This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
Mobility: Will likely be mobile in the environment.

Section 13: Disposal Considerations

Waste Disposal: Waste must be disposed of in accordance with federal, state, and local environmental control regulations.

Section 14: Transport Information

DOT USA & ADR/RID Europe: Not dangerous goods.
IMDG & IATA: Not dangerous goods.

Section 15: Other Regulatory Information

USA Regulations:
SARA 313: Not applicable
SARA 311/312 Hazard Categories: Not applicable
California Prop 65: California No Significant Risk Level: None of the chemicals in this product are listed.

Section 16 - Additional Information

Disclaimer:
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Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
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