Sodium Propyl Paraben, Sodium Propylparaben or Sodium Propyl Hydroxybenzoate BP USP NF Manufacturers, with SDS GHS MSDS Sheet

Supplier, Manufacturer, Exporter of Sodium Propyl Paraben, Sodium Propylparaben or Sodium Propyl Hydroxybenzoate, Muby Chemicals of Mubychem Group, established in 1976, is the original manufacturers of Specialty Chemicals, Pharmaceutical Excipient, Fragrance Food & Flavor chemicals, Reagent Grade Chemicals, Shale Gas Fracturing Chemicals in India. Mubychem Group has several manufacturing facilities spread across Western India and world wide contacts and toll manufacturers. We are exporting globally to countries like USA, Canada, Europe, UAE, South Africa, Tanzania, Kenya, Egypt, Nigeria, Cameroon, Uganda, Turkey, Mexico, Brazil, Chile, Argentina, Dubai, Korea, Vietnam, Thailand, Malaysia, Indonesia, Australia, China, Germany, France, Italy, Portugal etc.

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Sodium Propylparaben or Sodium Propyl Hydroxybenzoate: CAS Number: 35285-69-9, EINECS EC Number: 252-488-1, Molecular Formula: C10H11NaO3, Molecular Weight: 202.18, HS Code ---**

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SDS MSDS Sheet of Sodium Propyl Paraben, Sodium Propylparaben or Sodium Propyl Hydroxybenzoate Manufacturers

Sodium Propyl Paraben
Sodium Propylparaben or Sodium Propyl Hydroxybenzoate BP USP NF Pure Suppliers
Sodium Propyl Paraben, Sodium Propylparaben or Sodium Propyl Hydroxybenzoate

We supply several preservatives like Sodium Benzoate, Methyl Paraben, Ethyl Paraben, Propyl Paraben, Butyl Paraben, Heptyl Paraben, Sodium Methyl Paraben, Sodium Ethyl Paraben, Sodium Propyl Paraben, Sodium Butyl Paraben, Potassium Sorbate, Sodium diacetate, etc.

Sodium propyl p-hydroxybenzoate, the sodium salt of propylparaben, a compound with formula Na(C3H7(C6H4COO)O), is also used as a food additive and as an anti-fungal preservation agent. Its E number is E217.

Sodium Propyl Hydroxybenzoate BP Grade
Sodium Propylparaben
Sodium Propyl Parahydroxybenzoate, Ph Eur

C10H11NaO3 --- 202.2 --- CAS 35285-69-9
Action and use: Antimicrobial preservative.

DEFINITION
Sodium propyl parahydroxybenzoate contains not less than 99.0 per cent and not more than the equivalent of 104.0 per cent of sodium 4-(propoxycarbonyl)phenolate, calculated with reference to the anhydrous substance.

CHARACTERS
A white or almost white, crystalline powder, freely soluble in water, sparingly soluble in alcohol, practically insoluble in methylene chloride.

IDENTIFICATION
First identificationıA, B, E.
Second identificationıA, C, D, E.
A. Dissolve 0.5 g in 50 ml of water. Immediately add 5 ml of hydrochloric acid. Filter, and wash the precipitate with water. Dry at 80C in vacuo for 2 h. The melting point of the precipitate is 96C to 99C.
B. Examine the precipitate obtained in identification test A by infrared absorption spectrophotometry, comparing with the spectrum obtained with propyl parahydroxybenzoate CRS.
C. Examine the chromatograms obtained in the test for related substances. The principal spot in the chromatogram obtained with test solution (b) is similar in position and size to the principal spot in the chromatogram obtained with reference solution (c).
D. To about 10 mg in a test-tube add 1 ml of sodium carbonate solution, boil for 30 s and cool. Add 5 ml of aminopyrazolone solution and 1 ml of potassium ferricyanide solution and mix. An orange to red colour develops.
E. To 1 ml of solution S (see Tests) add 1 ml of water. The solution gives reaction (a) of sodium.

TESTS
Solution S: Dissolve 5.0 g in carbon dioxide-free water prepared from distilled water, and dilute to 50 ml with the same solvent.
Appearance of solution: Solution S, examined immediately after preparation, is clear and not more intensely coloured than reference solution.
pH: Dilute 1 ml of solution S to 100 ml with carbon dioxide-free water. The pH of the solution is 9.5 to 10.5.
Related substances: To pass the test.
Chlorides: To 10 ml of solution S add 30 ml of water and 1 ml of nitric acid and dilute to 50 ml with water. Shake and filter. Dilute 10 ml of the filtrate to 15 ml with water. The solution complies with the limit test for chlorides (350 ppm). Prepare the standard using 14 ml of chloride standard solution (5 ppm Cl) to which 1 ml of water has been added.
Sulphates: To 25 ml of solution S add 5 ml of distilled water and 10 ml of hydrochloric acid and dilute to 50 ml with distilled water. Shake and filter. Dilute 10 ml of the filtrate to 15 ml with distilled water. The solution complies with the limit test for sulphates (300 ppm).
Heavy metals: 2.0 g complies with limit test C for heavy metals (10 ppm). Prepare the standard using 2 ml of lead standard solution (10 ppm Pb).
Water: Not more than 5.0 per cent, determined on 0.500 g by the semi-micro determination of water.

ASSAY
Dissolve 0.150 g in 50 ml of anhydrous acetic acid. Titrate with 0.1 M perchloric acid, determining the end-point potentiometrically. 1 ml of 0.1 M perchloric acid is equivalent to 20.22 mg of C10H11NaO3.

IMPURITIES
A. R = H: 4-hydroxybenzoic acid,
B. R = CH3 : methyl 4-hydroxybenzoate,
C. R = CH2-CH3: ethyl 4-hydroxybenzoate,
D. R = CH2-CH2-CH2-CH3: butyl 4-hydroxybenzoate.


Propylparaben Sodium USP NF Grade

Propylparaben Sodium contains not less than 98.5 percent and not more than 101.5 percent of C10H11NaO3, calculated on the anhydrous basis.

Completeness of solution: One g of it, dissolved in water, meets the requirement.
Identification:
A: Dissolve 0.5 g in 5 mL of water, acidify with hydrochloric acid, and filter the resulting precipitate. Wash the precipitate with water, and dry it over silica gel for 5 hours: the IR absorption spectrum of a mineral oil dispersion of it exhibits maxima only at the same wavelengths as that of a similar preparation of USP Propylparaben.
B: Ignite about 0.3 g, cool, and dissolve the residue in about 3 mL of 3 N hydrochloric acid. A platinum wire dipped in this solution imparts an intense, persistent yellow color to a nonluminous flame.
pH: between 9.5 and 10.5, in a solution (1 in 1000).
Water: not more than 5.0%.
Chloride: A 0.2-g portion shows no more chloride than corresponds to 0.10 mL of 0.020 N hydrochloric acid (0.035%).
Sulfate: A 0.25-g portion shows no more sulfate than corresponds to 0.30 mL of 0.020 N sulfuric acid (0.12%).
Assay: Gently reflux about 100 mg of Propylparaben Sodium, accurately weighed, with 30 mL of 1 N sodium hydroxide for 30 minutes. Cool, add 25.0 mL of potassium bromate solution (2.78 in 500), 5 mL of potassium bromide solution (1 in 8), and 10 mL of hydrochloric acid, and immediately insert the stopper into the flask. Cool, shake for 15 minutes, and allow to stand for 15 minutes. Quickly add 15 mL of potassium iodide, taking care to avoid the escape of bromine vapor, at once replace the stopper in the flask, and shake vigorously. Rinse the stopper and the neck of the flask with a small quantity of water, and titrate the liberated iodine with 0.1 N sodium thiosulfate, adding 3 mL of starch as the endpoint is approached. [NOTE—About 15 mL is needed.] Perform a blank determination, and note the difference in volumes required. Each mL of the difference in volume of 0.1 N sodium thiosulfate is equivalent to 3.37 mg of C10H11NaO3.

For Original Monographs of IP Indian Pharmacopoeia BP British Pharmacopoeia USP US Pharmacopoeia FCC Food Grade product, please check with the respective web-pages or books.

Manufacturers Suppliers:

MUBY CHEMICALS
Ambernath Mumbai, Ankleshwar Gujarat, India
TEL: (OFFICE) 91-22-23770100, 23726950
Current Date Time in India GMT+5:30

e-mail: info@mubychem.com

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neighbouring buyers may
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Call toll-free 1-844-682-9243 (1-844-MUBYCHEM)

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Last 27 August, 2022

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Sodium Propylparaben, Sodium Propyl Paraben, Sodium Propyl hydroxybenzoate SDS, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet

1. PRODUCT DESCRIPTION

Product Name & Other Names: Sodium Propylparaben or Sodium Propyl Paraben or Sodium Propyl hydroxybenzoate.
CAS Number: 35285-69-9
EINECS EC Number
: 252-488-1
Molecular Weight: 202.18
Molecular Formula: C10H11NaO3
Relevant uses and uses advised against (if any): Industrial Manufacturing.
Suppliers: As per letterhead.

2. HAZARD IDENTIFICATION

GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008

Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
This substance is not classified as dangerous according to Directive 67/548/EEC.

Labeling according to GHS & Regulation (EC) No 1272/2008

GHS Label Elements
None

Signal Words: None

Hazards not otherwise classified (HNOC):
May causes mild skin irritation.
May causes eye mild irritation.

Precautionary statements:
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P262: Do not get in eyes, on skin, or on clothing.
P281: Use personal protective equipment as required.
P302+P352 - IF ON SKIN: Wash with plenty of soap and water.
P304 + P340 - IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+313: If eye irritation persists get medical advice/attention.

3. COMPOSITION/INFORMATION ON INGREDIENTS

Product Name & Other Names: Sodium Propylparaben or Sodium Propyl Paraben or Sodium Propyl hydroxybenzoate.
CAS Number: 35285-69-9
EINECS EC Number
: 252-488-1

4. FIRST AID MEASURES

Always get medical attention after the first aid is over.

Emergency and First Aid Procedures:
Eyes - Flush with water for at least 15 minutes, raising and lowering eyelids occasionally. Get medical attention if irritation persists.
Skin - Thoroughly wash exposed area for at least 15 minutes. Remove contaminated clothing. Launder contaminated clothing before reuse. Get medical attention if irritation persists.
Ingestion - If swallowed, if conscious, give plenty of water. Immediately call a physician. Never give anything by mouth to an unconscious person.
Inhalation - Remove to fresh air. Give oxygen if breathing is difficult; give artificial respiration if breathing has stopped. Get medical attention.

5. FIREFIGHTING PROCEDURES

Extinguisher Media: Use media suitable to extinguish surrounding fire. Use water spray, alcohol-resistant foam, dry chemical, or carbon dioxide.
Flammable Limits in Air % by Volume: N/A
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes. Fire-extinguishing work is done from the windward and the suitable fire-extinguishing method according to the surrounding situation is used. Uninvolved persons should evacuate to a safe place.

6. SPILL OR LEAK PROCEDURES

Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment Cleanup procedures and Storage: Do not inhale dust, vapors, mist, or gas. Avoid dust formation. Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g. sand, earth, diatomaceous earth, vermiculite). Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and allow to evacuate as per law.

7. SPECIAL PRECAUTIONS

Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. In case of insufficient ventilation, wear suitable respiratory equipment. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like strong oxidizing agents.

8. SPECIAL PROTECTION INFORMATION

Exposure Guidelines: This product, as supplied, does not contain any hazardous materials with occupational exposure limits established by the region specific regulatory bodies.
Respiratory Protection (Specify Type): None needed under normal conditions of use with adequate ventilation. NIOSH approved equipment should be worn if PELs are exceeded.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Dust deposits on floors and other surfaces may pick up moisture and cause the surfaces to become slippery and present safety hazards. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.

9. PHYSICAL DATA

Appearance: White to off-white powder.
Odor: odorless.
Odor threshold: Not available.
pH: 9-10
Relative density: Not available.
Melting point/freezing point: Not available.
Initial boiling point and boiling range: Not available.
Flash point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility in Water: Soluble.
Viscosity: Not available.
Molecular Weight: 202.18
Molecular Formula: C10H11NaO3

10. REACTIVITY DATA

Stability: It is stable
Conditions to Avoid: Heat, humidity, Dust generation.
Incompatibility (Materials to Avoid): Strong oxidizing agents, Extremes of temperature and direct sunlight.
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide
Hazardous Polymerization: Will not occur.

11. TOXICITY DATA

Toxicity Data: LD50 Rat: LD50 Oral - Mouse - 3,700 mg/kg.
Carcinogenicity: No component of this product present at levels greater than or equal to 0.1% is identified as possible or confirmed human carcinogen by IARC, ACGIH, OSHA and NTP.
Teratogenic Effects: Not available.
Mutagenic Effects: Not available.
Developmental Toxicity: Not available.
Reproductive Effects: No information available.

12. ECOLOGICAL DATA

Toxicity to fish: Not available. May cause long lasting harmful effects to aquatic life.
Toxicity to fish: No information available.
Persistence and Degradability: Unlikely to persist due to water solubility.
Mobility: Likely to be mobile due to water solubility.
Bioaccumulation/ Accumulation: Not likely to bioaccumulate.
Results of PBT and vPvB assessment: No data available for assessment.

13. DISPOSAL INFORMATION

Waste Disposal Methods: Dispose in accordance with all applicable Federal, State and Local regulations.

14. TRANSPORT INFORMATION

DOT USA, TDG Canada & ADR/RID Europe
Not regulated.
IMDG/IMO
Not regulated.
IATA
Not regulated.

15. REGULATORY INFORMATION

USA:
California Proposition 65
: Not listed.
SARA 311/312 Hazards: See section 2.

16. ADDITIONAL INFORMATION

Disclaimer:
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Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
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