2,2,2-Trifluoroethanol or TFE or Trifluoroethyl alcohol Manufacturers, with SDS GHS MSDS Sheet |
Supplier, Manufacturer, Exporter of 2,2,2-Trifluoroethanol or TFE, Muby Chemicals of Mubychem Group, established in 1976, is the original manufacturers of Specialty Chemicals, Pharmaceutical Excipient, Fragrance Food & Flavor chemicals, Reagent Grade Chemicals, Shale Gas Fracturing Chemicals in India. Mubychem Group has several manufacturing facilities spread across Western India and world wide contacts and toll manufacturers. We are exporting globally to countries like USA, Canada, Europe, UAE, South Africa, Tanzania, Kenya, Egypt, Nigeria, Cameroon, Uganda, Turkey, Mexico, Brazil, Chile, Argentina, Dubai, Korea, Vietnam, Thailand, Malaysia, Indonesia, Australia, China, Germany, France, Italy, Portugal, Bangladesh, etc. The products are offered as per required specifications and in correct shape and size in mm or meshs or microns as specified by the buyer. The participating units have one or more accreditations like FDA - cGMP and GLP approval, ISO-9001 Certified, "REACH" Registered, ISO-14001, ISO/IEC 17025, ISO-22000, FSSC 22000, ISO 45001, Kosher Certified, Halal Certified, HACCP, FSSAI. We offer Commercial Pure & IP BP EP Ph Eur USP NF JP FCC Food Grade Analytical Reagent Grades of Chemicals |
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2,2,2-Trifluoroethanol or TFE or Trifluoroethyl alcohol: CAS Number: 75-89-8, EINECS EC Number: 200-913-6, Molecular Formula: C2H3F3O or CF3CH2OH, Molecular Weight: 100.04, HS Code ---**
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SDS MSDS Sheet of 2,2,2-Trifluoroethanol or TFE or Trifluoroethyl alcohol Manufacturers
2,2,2-Trifluoroethanol
TFE or Trifluoroethyl alcohol Pure Suppliers
2,2,2-Trifluoroethanol or TFE or Trifluoroethyl alcohol is the organic compound with the formula CF3CH2OH. It is colorless, water-miscible liquid has a smell reminiscent of ethanol. 2,2,2-Trifluoroethanol is used as a solvent in organic chemistry, nylon, and pharmaceutical industry. Oxidations of sulfur compounds using hydrogen peroxide are effectively conducted in TFE. In biology 2,2,2-Trifluoroethanol is used as a co-solvent in protein folding studies with NMR spectroscopy: this solvent can effectively solubilize both peptides and proteins.
General Properties and Specifications of 2,2,2-Trifluoroethanol or TFE:
CAS Number: 75-89-8.
Appearance: Colorless and transparent liquid.
Odor: Ethanol like.
Assay: 99.8%
pH: 5.83
Water: 0.0600% maximum.
Fluoride: 0.0007% maximum.
Chloride: 0.0007% maximum.
Relative density: around 1.4
Melting point: -43.5C.
Boiling point: 74C.
Flash point: 30C.
Autoignition Temperature: 188C.
Solubility: Miscible with water and ethanol.
N,O-Bis-(Trimethylsilyl) Trifluoro Acetamide
Manufacturers:
MUBY CHEMICALS
Ambernath Mumbai, Ankleshwar Gujarat, India
TEL: (OFFICE) +912223770100, +912223726950
Current Date Time in India GMT+5:30
e-mail: info@mubychem.com
USA, Canada, Mexico and other American
neighbouring buyers may
e-mail: us@mubychem.com
Call toll-free 1-877-682-9243 (1-877-MUBYCHEM)
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Last
18 May, 2024
Exporters to USA Canada UAE Europe South Africa Tanzania Kenya Uganda Egypt Nigeria Turkey Mexico Brazil Argentina Chile Dubai etc.
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2,2,2-Trifluoroethanol or TFE or Trifluoroethyl alcohol SDS GHS, Safety Data Sheet
MSDS GHS, Material Safety Data Sheet
1. Product Identification
Product Name & Other Names: 2,2,2-Trifluoroethanol or TFE or Trifluoroethyl alcohol.
CAS No.: 75-89-8
EINECS EC No.: 200-913-6
Molecular Formula: C2H3F3O or CF3CH2OH
Molecular Weight: 100.04
Relevant uses and uses advised against (if any): Industrial Manufacturing.
Suppliers: As per letterhead.
2. Hazards Identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Hazard Class and Category Code(s), Regulation (EC) No 1272/2008 (CLP):
Flammable liquids (Category 3) H226
Acute toxicity, Oral (Category 3) H301
Serious eye damage (Category 1) H318
Acute toxicity, Inhalation (Category 3) H331
Reproductive toxicity (Category 1B) H360F
Specific target organ toxicity - repeated exposure (Category 2) Blood, H373
Labeling according Regulation (EC) No 1272/2008
GHS Label Elements  Toxic |
GHS Label Elements |
GHS Label Elements |
GHS Label Elements |
Signal Words: Danger
Hazard statements:
H226: Flammable liquid and vapor.
H301: Toxic if swallowed.
H331: Toxic if inhaled.
H318 Causes serious eye damage
H360F May damage fertility.
H373 May cause damage to organs through prolonged or repeated exposure.
Precautionary statements:
P210: Keep away from heat/sparks/open flames/hot surfaces – No smoking.
P233: Keep container tightly closed.
P240: Ground/bond container and receiving equipment.
P241: Use explosion-proof electrical/ventilating/light/…/equipment.
P242: Use only non-sparking tools.
P243: Take precautionary measures against static discharge.
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P264: Wash … thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P273: Avoid release to the environment.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P330: Rinse mouth.
P362: Take off contaminated clothing and wash before reuse.
P391: Collect spillage.
P301+310: IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P302+352: IF ON SKIN: Wash with soap and water.
P303+361+353: IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
P304+340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305+351+338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do – continue rinsing.
P370+378: In case of fire: Use water spray or fog for extinction.
P403+233+235: Store in a well-ventilated place. Keep container tightly closed. Keep cool.
P405: Store locked up.
P501: Dispose of contents/container to authorized agents only.
Classification according to EU Directives 67/548/EEC or 1999/45/EC:
Hazard symbols:
F = Flammable.
T = Toxic
C = Corrosive.
R-phrases:
R10 Flammable.
R23/25 Toxic by inhalation and if swallowed.
R34 Causes burns
R41 Risk of serious damage to eyes.
R46 May cause inheritable genetic damage.
R48 Danger of serious damage to health by prolonged exposure.
3. Composition/Information on Ingredients
Product Name & Other Names: 2,2,2-Trifluoroethanol or TFE or Trifluoroethyl alcohol.
CAS No.: 75-89-8
EINECS EC No.: 200-913-6
4. First Aid Measures
Always seek medical attention after first aid measures are provided.
Inhalation: Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.
Ingestion: Never give anything by mouth to an unconscious person. Get medical attention.
Skin Contact: Wipe off excess material from skin then immediately flush skin with plenty of water for at least 15 minutes. Remove contaminated clothing and shoes. Get medical attention. Wash clothing before reuse. Thoroughly clean shoes before reuse. Get medical attention.
Eye Contact: Immediately flush eyes with plenty of water for at least 15 minutes, lifting lower and upper eyelids occasionally. Get medical attention immediately.
5. Fire Fighting Measures
Flammability of the Product: Flammable. Vapors may form explosive mixtures with air.
Flash Points: 30C.
Products of Combustion: Carbon dioxide, Carbon monoxide, fumes & Hydrofluoric Acid.
Fire: Inflammable.
Explosion: Explosive in presence of heat.
Fire Extinguishing Media: Use water spray or fog, dry chemical, alcohol-resistant foam. Water mist may be used to cool closed containers. Flammable liquid and vapor. Vapors are heavier than air and may travel to a source of ignition and flash back. Vapors can spread along the ground and collect in low or confined areas. Never direct a water jet in the container to prevent any splashing of the product which could cause spreading of the fire. Cool containing vessels with water jet in order to prevent pressure build-up, auto-ignition or explosion.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes. Fire-extinguishing work is done from the windward and the suitable fire-extinguishing method according to the surrounding situation is used. Uninvolved persons should evacuate to a safe place.
6. Accidental Release Measures
Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment Cleanup procedures and Storage: Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g. sand, earth, diatomaceous earth, vermiculite). Vacuum or sweep up and remove to an approved disposal container.
Small Spill: Avoid mist formation. Avoid breathing mist. Ensure adequate ventilation. Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to local and regional authority requirements.
Large Spill: Remove all sources of ignition. Provide proper ventilation. Absorb the material on a porous, inert material such as earth, sand, or vermiculite. Carefully sweep up the material without causing dust. Dispose of in accordance with local regulations.
7. Handling and Storage
Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. In case of insufficient ventilation, wear suitable respiratory equipment. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Do not leave the material container open. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like strong oxidizing agents, strong bases, metals. Keep the product in its original container well sealed, in a dry and ventilated area, away from potential sources of ignition and protected from light. Protect against physical damage.
8. Exposure Controls/Personal Protection
Airborne Exposure Limits: Contains no substances with occupational exposure limit values. Work under hood. Do not inhale substance/mixture. Avoid generation of vapors/aerosols.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.
9. Physical and Chemical Properties
Appearance: Colorless and transparent liquid..
Odor: Ethanol like odor.
Odor threshold: Not available.
pH: Not available.
Relative Density: around 1.4
Boiling Point: 74C
Melting Point: -43.5C.
Flash point: 30C.
Auto-ignition temperature: 188C.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor Pressure (mm Hg): 4.87mmHg @ 25C.
Vapor Density (Air=1): 4.3.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility: Miscible with water and ethanol.
Viscosity: Not available.
Molecular Formula: C2H3F3O or CF3CH2OH
Molecular Weight: 100.04
10. Stability and Reactivity
Stability: Stable under ordinary conditions of use and storage. Vapor/air-mixtures are explosive at intense warming.
Hazardous Decomposition Products: It emits Carbon dioxide, Carbon monoxide Hydrofluoric acid & Fumes.
Hazardous Polymerization: Will not occur.
Incompatibilities: Strong oxidizing agents, strong bases, metals.
Conditions to Avoid: Incompatibles, moisture, heat & light, sparks, flame.
11. Toxicological Information
Toxicity data
Oral-Rat LD50: 153 mg/kg
Dermal Rat LD50: >2000 mg/kg>
Inhalation LC50 Rat: 3.25 mg/l784 ppm; 4 h ; vapor
Carcinogenicity: May cause cancer.
No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.
Epidemiology: No information found
Teratogenicity: No information found
Reproductive Effects: May damage fertility.
Mutagenicity: No information found
Neurotoxicity: No information found
12. Ecological Information
Toxicity to fish: LC50: 105 - 135 mg/L, 96h flow-through (Pimephales promelas).
Toxicity to daphnia and other aquatic invertebrates: semi-static test EC50 - Daphnia magna (Water flea) - > 1.000 mg/l - 48 h.
Persistence and Degradability: No data available for assessment.
Mobility: Will likely be mobile in the environment due to its volatility.
Bioaccumulation/ Accumulation: Bioaccumulation is not expected.
Results of PBT and vPvB assessment: No data available for assessment.
13. Disposal Considerations
Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. Processing use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose of container and unused contents in accordance with law.
14. Transport Information
DOT USA, TDG Canada & ADR/RID Europe:
UN Number: UN 1992
Shipping Name: FLAMMABLE LIQUID, TOXIC, N.O.S. (2,2,2- TRIFLUOROETHANOL)
Hazard Class: 3 (6.1); Packing Group: III
IMDG/IMO:
UN Number: UN 1992
Shipping Name: FLAMMABLE LIQUID, TOXIC, N.O.S. (2,2,2- TRIFLUOROETHANOL)
Hazard Class: 3 (6.1); Packing Group: III
IATA/ICAO
UN Number: UN 1992
Shipping Name: FLAMMABLE LIQUID, TOXIC, N.O.S. (2,2,2- TRIFLUOROETHANOL)
Hazard Class: 3 (6.1); Packing Group: III
15. Regulatory Information
USA:
SARA 302 Components: Not are subject to the reporting of SARA Title III, Section 302.
SARA 313 Components: No chemicals are reportable under Section 313.
SARA 311/312 Hazards: Fire Hazard: Immediate Health Hazard: Acute. See section 2.
16. Other Information
European Labeling in Accordance with EC Directives:
H226 Flammable liquid and vapor.
H301 Toxic if swallowed.
H331 Toxic if inhaled.
H318 Causes serious eye damage
H360F May damage fertility.
H373 May cause damage to organs through prolonged or repeated exposure.
Hazard symbols:
F = Flammable.
T = Toxic
C= Corrosive.
R-phrases:
R 10 Flammable.
R23/25 Toxic by inhalation and if swallowed.
R34 Causes burns
R41 Risk of serious damage to eyes.
R46 May cause inheritable genetic damage.
R48 Danger of serious damage to health by prolonged exposure.
Disclaimer:
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Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
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