Trichloroacetic Acid or TCA or TCAA or Trichloroethanoic Acid BP Ph Eur Analytical Reagent Grade Manufacturers, with SDS GHS MSDS Sheet

Supplier, Manufacturer, Exporter of Trichloroacetic Acid or TCA or TCAA or Trichloroethanoic Acid, Muby Chemicals of Mubychem Group, established in 1976, is the original manufacturers of Specialty Chemicals, Pharmaceutical Excipient, Fragrance Food & Flavor chemicals, Reagent Grade Chemicals, Shale Gas Fracturing Chemicals in India. Mubychem Group has several manufacturing facilities spread across Western India and world wide contacts and toll manufacturers. We are exporting globally to countries like USA, Canada, Europe, UAE, South Africa, Tanzania, Kenya, Egypt, Nigeria, Cameroon, Uganda, Turkey, Mexico, Brazil, Chile, Argentina, Dubai, Korea, Vietnam, Thailand, Malaysia, Indonesia, Australia, China, Germany, France, Italy, Portugal, Bangladesh, etc.

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Trichloroacetic Acid or TCA or TCAA or Trichloroethanoic Acid CAS Number 76-03-9, EINECS EC Number: 200-927-2, Molecular Formula: C2HCl3O2, Molecular Weight: 163.38, HS Code 29154030 or 29154000

Specifications, Safety Data Sheet, Manufacturing process details, Wholesale retail buy sell prices, Uses etc available on line in these pages for Trichloroacetic Acid or TCA or TCAA or Trichloroethanoic Acid.

Trichloroacetic Acid or TCA or TCAA or Trichloroethanoic Acid is an analogue of acetic acid. It is widely used in biochemistry for the precipitation of macromolecules, such as proteins and used in cosmetic treatments.

General Properties and Specifications of Trichloroacetic Acid or TCA or TCAA or Trichloroethanoic Acid:
Appearance: Colorless to white, crystalline solid. Hygroscopic.
Assay: 99%
Odor: Sharp, pungent.
Relative density: about 1.63
Melting point: 55C to 58C literature.
Boiling point: 196C to 197C.
Flash point: >113C.
Solubility: Soluble in water.
Storage: At less than 30C.

Trichloroacetic Acid BP Ph Eur Grade Specifications:
C2HCl3O2 --- 163.4 --- CAS 76-03-9
Preparation: Trichloroacetic Acid Solution

DEFINITION
2,2,2-Trichloroacetic acid.
Content: 98.0 per cent to 100.5 per cent.

CHARACTERS
Appearance: White or almost white, crystalline mass or colourless crystals, very deliquescent.
Solubility: Very soluble in water, in ethanol (96 per cent) and in methylene chloride.

IDENTIFICATION
First identification: A.
Second identification: B, C
A. Infrared absorption spectrophotometry.
B. To 0.5 mL of solution S (see Tests) add 2 mL of pyridine and 5 mL of strong sodium hydroxide solution. Shake vigorously and heat in a water-bath at 60-70C for 5 minutes. The upper layer shows an intense red colour.
C. Solution S is strongly acidic.

TESTS
Solution S: Dissolve 2.5 g in water and dilute to 25 mL with the same solvent.
Appearance of solution: Solution S is clear and not more intensely coloured than reference solution.
Chlorides: Maximum 100 ppm.
Sulfated ash: Maximum 0.1 per cent, determined on 1.0 g.

Trichloroacetic Acid Analytical Reagent Grade:
CCl3COOH Formula Weight 163.39
CAS Number 76-03-9

For Original Monographs of IP Indian Pharmacopoeia BP British Pharmacopoeia USP US Pharmacopoeia FCC Food Grade product, please check with the respective web-pages or books.

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Trichloroacetic Acid or TCA or TCAA or Trichloroethanoic Acid
SDS Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet 27-July-23

Product Name & Other Names: Trichloroacetic Acid or TCA or TCAA or Trichloroethanoic Acid.
CAS No.: 76-03-9
EINECS EC Code: 200-927-2
Molecular Weight: 163.38
Chemical Formula: C2HCl3O2
Relevant uses and uses advised against (if any): Industrial Manufacturing.
Suppliers: As per letterhead.

GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008

Hazard Statements:
H314 Causes severe skin burns and eye damage.
H410 Very toxic to aquatic life with long lasting effects.

Precautionary Statements
P260: Do not breathe dust/fume/gas/mist/vapors/spray.
P264: Wash ... thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P273 Avoid release to the environment.
P280-Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352: IF ON SKIN: Wash with soap and water.
P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P332+P313: If skin irritation occurs: Get medical advice/attention.
P337+P313: If eye irritation persists: Get medical advice/ attention.
P390: Absorb spillage to prevent material damage.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container in accordance with local/regional/national/international regulations.

Classification according to EU Directives 67/548/EEC or 1999/45/EC:
Hazard Symbols:
C Corrosive
N Dangerous for the environment
Risk Phrase:
R34 Causes burns
R41 Risk of serious damage to eyes
R51/53 Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.

Product Name & Other Names: Trichloroacetic Acid or TCA or TCAA or Trichloroethanoic Acid.
CAS No.: 76-03-9
EINECS EC Code: 200-927-2

Always seek medical attention after first aid measures are provided.
Inhalation: If is inhaled, it will cause irritation and damage to the nose and throat. It can cause headaches, bleeding from nose coughing and chest discomfort. Remove the victim to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.
Ingestion: It will cause irritation and burns to mouth, digestive tract and stomach. It may lead to pain, nausea, vomiting, and even collapse. Contact the medical center quickly. Never give anything by mouth to an unconscious person. Get medical attention.
Skin Contact: On contact, it can cause itching, pain, swelling and redness. Immediately flush skin with plenty of water for at least 15 minutes. Remove contaminated clothing and shoes. Get medical attention. Wash clothing before reuse. Thoroughly clean shoes before reuse.
Eye Contact: It can cause severe damage to eyes. Check for and remove any contact lenses. Immediately flush your eyes with running water for at least 15 minutes, keeping eyelids open. Cold water may be used. Get medical attention.

Fire: Flash point: >113C. The material is combustible.
Toxic fumes, carbon dioxide, carbon monoxide, hydrogen chloride may be formed in fire.
Fire Extinguishing Media: Dry chemical, foam or carbon dioxide and water spray jet. No limitation of suitable extinguishing media is specified, however, avoid solid water jet.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes.

Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment cleanup procedures and Storage:
Small Spill: Mop and pick up the material and place in an appropriate waste disposal container. Soak up with inert absorbent material and dispose of it as hazardous waste. Finish cleaning by spreading water on the contaminated surface and dispose of according to local and regional authority requirements.
Large Spill: Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g., sand, earth, diatomaceous earth, vermiculite). Avoid mist formation. Wear full protective equipment and ensure proper ventilation. Keep away from heat. Keep away from sources of ignition. Provide ventilation. Vacuum or sweep up and remove to disposal container.

Precautions for safe handling: Keep away from heat and source of fire, preferably in a ventilated area. Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Keep locked up in tightly closed container. Do not leave the material container open. Store protected from heat, sparks and ignition sources and incompatible materials. Do not ingest. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like oxidizing agents, acids, bases and reducing agents. Containers may be hazardous when empty since they retain product residues. Do not store near food items. Light sensitive. Store under inert gas. Moisture sensitive.

Airborne Exposure Limits: This product does not contain any hazardous materials with occupational exposure limits established by the region-specific regulatory bodies.
Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area. Please refer to the ACGIH document, Industrial Ventilation, A Manual of Recommended Practices, most recent edition, for details.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to the substance is apparent and engineering controls are not feasible, consult an industrial hygienist. For emergencies, or instances where the exposure levels are not known, use a full-face piece positive-pressure, air-supplied respirator. WARNING: Air purifying respirators do not protect workers in oxygen-deficient atmospheres.
Skin Protection: Wear impervious protective clothing, including boots, gloves, lab coat, apron, or coveralls, as appropriate, to prevent skin contact.
Eye Protection: Use chemical safety goggles and/or a full-face shield where splashing is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Dust deposits on floors and other surfaces may pick up moisture and cause the surfaces to become slippery and present safety hazards. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.

Appearance: Colorless to white, crystalline solid. Hygroscopic.
Odor: Sharp, pungent.
Odor threshold: Not available.
pH: Acidic.
Relative density: about 1.63
Melting point/freezing point: 55C to 58C literature.
Initial boiling point and boiling range: 196C to 197C.
Flash point: >113C.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility: Soluble in water.
Viscosity: Not available.
Molecular Weight: 163.38
Chemical Formula: C2HCl3O2

Stability: Stable under ordinary conditions of use and storage.
Hazardous Decomposition Products: Carbon dioxide, carbon monoxide, hydrogen chloride and toxic fumes may form when heated to decomposition.
Hazardous Polymerization: Not reported.
Incompatibilities: Oxidizing agents, acids, bases and reducing agents.
Conditions to Avoid: Heat, flames, ignition sources and incompatibles.

LD50 Oral Rat: 3320 mg/kg.
Carcinogenicity: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible, or confirmed human carcinogen by IARC, ACGIH, OSGHA or NTP.
Mutagenic Effects: Not available.
Teratogenic Effects: Not available.
Developmental Toxicity: Not available.
Reproductive Effects: No information available.

Toxicity to fish: Not available.
Biodegradability: The product is biodegradable. Unlikely to persist due to water solubility.
Mobility: Likely to be mobile due to water solubility.
Bioaccumulation/ Accumulation: No information available.
Results of PBT and vPvB assessment: No data available for assessment.

Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. Processing use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose of containers and unused contents in accordance with federal, state, and local requirements.

DOT USA & ADR/RID Europe
UN Number: 1839
Proper shipping name: Trichloroacetic acid
Class: 8, Packing group: II.
IMDG & IATA
UN Number: 1839
Proper shipping name: Trichloroacetic acid
Class: 8, Packing group: II.

European Labeling in Accordance with EC Directives:
H314 Causes severe skin burns and eye damage.
H410 Very toxic to aquatic life with long lasting effects.

Disclaimer:
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Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
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