Trifluoroacetic Acid or TFA Manufacturers, with SDS GHS MSDS Sheet |
Supplier, Manufacturer, Exporter of Trifluoroacetic Acid or TFA, Muby Chemicals of Mubychem Group, established in 1976, is the original manufacturers of Specialty Chemicals, Pharmaceutical Excipient, Fragrance Food & Flavor chemicals, Reagent Grade Chemicals, Shale Gas Fracturing Chemicals in India. Mubychem Group has several manufacturing facilities spread across Western India and world wide contacts and toll manufacturers. We are exporting globally to countries like USA, Canada, Europe, UAE, South Africa, Tanzania, Kenya, Egypt, Nigeria, Cameroon, Uganda, Turkey, Mexico, Brazil, Chile, Argentina, Dubai, Korea, Vietnam, Thailand, Malaysia, Indonesia, Australia, China, Germany, France, Italy, Portugal, Bangladesh, etc. The products are offered as per required specifications and in correct shape and size in mm or meshs or microns as specified by the buyer. The participating units have one or more accreditations like FDA - cGMP and GLP approval, ISO-9001 Certified, "REACH" Registered, ISO-14001, ISO/IEC 17025, ISO-22000, FSSC 22000, ISO 45001, Kosher Certified, Halal Certified, HACCP, FSSAI. We offer Commercial Pure & IP BP EP Ph Eur USP NF JP FCC Food Grade Analytical Reagent Grades of Chemicals |
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Trifluoroacetic Acid or TFA CAS Number 76-05-1, EINECS EC Number: 200-929-3, Molecular Formula: C2HF3O2, Molecular Weight: 114.02, HS Code 29159093 or 2915 90 70
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SDS MSDS Sheet of Trifluoroacetic Acid or TFA Manufacturers
Trifluoroacetic Acid
TFA Suppliers
Trifluoroacetic acid TFA is a colorless liquid with a vinegar-like odor. TFA is a stronger acid than acetic acid. TFA is the precursor to many other fluorinated compounds. It is a reagent used in organic synthesis because of a combination of convenient properties: volatility, solubility in organic solvents, and its strength as an acid.
General Properties and Specifications of Trifluoroacetic Acid or TFA:
Appearance: Clear colorless fuming liquid.
Odor: Pungent vinegar like.
Assay: 99.9% minimum.
pH: 1 (10 g/L).
Water (KF): 0.05% maximum.
Relative density: 1.49
Melting point: -15.4C.
Boiling point: 72.4C.
Flash point: >100C.
Solubility: Miscible with water.
Storage: Below 30C.
We also manufacture and supply as under:
2,5-Bis-(2,2,2-Trifluoroethoxy) Benzoic Acid
N,O-Bis-(Trimethylsilyl) Trifluoro Acetamide
Manufacturers:
MUBY CHEMICALS
Ambernath Mumbai, Ankleshwar Gujarat, India
TEL: (OFFICE) +912223770100, +912223726950
Current Date Time in India GMT+5:30
e-mail: info@mubychem.com
USA, Canada, Mexico and other American
neighbouring buyers may
e-mail: us@mubychem.com
Call toll-free 1-877-682-9243 (1-877-MUBYCHEM)
Copyright and Usual Disclaimer is Applicable.
Last
18 May, 2024
Exporters to USA Canada UAE Europe South Africa Tanzania Kenya Uganda Egypt Nigeria Turkey Mexico Brazil Argentina Chile Dubai etc.
Global or International Suppliers, Exporters, Importers, Manufacturers
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Trifluoroacetic Acid or TFA SDS, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet 31-Aug-23
1. Product Identification
Product Name & Other Names: Trifluoroacetic Acid or TFA.
CAS No.: 76-05-1
EINECS EC Number: 200-929-3
Molecular Formula: C2HF3O2
Molecular Weight: 114.02
Relevant uses and uses advised against (if any): Laboratory and Industrial Use.
Supplier: As per letterhead.
2. Hazards Identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008
Skin corrosion (Category 1B) H314
Acute toxicity, Inhalation (Category 4) H332
Long-term (chronic) aquatic hazard (Category 3) H412
Labeling according to GHS USA & Regulation (EC) No 1272/2008
GHS Label Elements  Corrosive |
Signal Words: Danger
Hazard Statements:
H332: Harmful if inhaled.
H314: Causes severe skin burns and eye damage.
H412 Harmful to aquatic life with long lasting effects.
Precautionary Statements:
P260: Do not breathe dust/fume/gas/mist/vapors/spray.
P264: Wash contaminated parts thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P302+352: IF ON SKIN: Wash with plenty of soap and water.
P304+P340+P312: IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/doctor if you feel unwell.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P333+313: If skin irritation or a rash occurs: Get medical advice/attention.
P403+233+235: Store in a well-ventilated place. Keep container tightly closed. Keep cool.
P405: Store locked up.
P501: Dispose of contents/container in accordance with local/national regulation.
Classification according to EU Directives 67/548/EEC or 1999/45/EC:
Hazard Symbols:
Xn Harmful.
C Corrosive.
Risk Phrases:
R20 Harmful by inhalation.
R35 Causes severe burns.
R41 Risk of serious damage to eyes.
R53 May cause long-term adverse effects in the aquatic environment.
3. Composition/Information on Ingredients
Product Name & Other Names: Trifluoroacetic Acid or TFA.
CAS No.: 76-05-1
EINECS EC Number: 200-929-3
4. First Aid Measures
Always seek medical attention after first aid measures are provided.
Inhalation: Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Do not use mouth-to-mouth method if victim inhaled the substance. Induce artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device. Get medical attention.
Ingestion: Rinse mouth. Do not induce vomiting without medical advice. If vomiting occurs naturally, have victim lean forward to reduce the risk of aspiration. Never give anything by mouth to a victim who is unconscious or is having convulsions. Get medical attention.
Skin Contact: Wipe off excess material from skin then immediately flush skin with plenty of water for at least 15 minutes. Use a mild soap if available. Remove contaminated clothing and shoes. Get medical attention. Wash clothing before reuse. Thoroughly clean shoes before reuse. For minor skin contact, avoid spreading material on unaffected skin.
Eye Contact: Immediately flush eyes with plenty of water for at least 15 minutes, lifting lower and upper eyelids occasionally. Get medical attention immediately.
5. Fire Fighting Measures
Flash Point: >100C
Products of Combustion: Carbon oxides, Fluorine compounds and fumes.
Fire Extinguishing Media: Water spray. Alcohol foam. Polymer foam. Dry chemical powder. Carbon dioxide (CO2). Avoid a solid water stream as it may scatter and spread fire. Fire residues and contaminated fire extinguishing water must be disposed of in accordance with local regulations. In the event of fire and/or explosion do not breathe fumes.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes.
6. Accidental Release Measures
Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment cleanup procedures and Storage:
Small Spill: Avoid dust/mist formation. Avoid breathing dust/mist/gas. Ensure adequate ventilation. Wipe up with absorbent material (e.g., cloth, fleece). Clean contaminated surface thoroughly.
Large Spill: Do not inhale dust, vapors, mist, or gas. Avoid dust formation. Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g., sand, earth, diatomaceous earth, vermiculite). Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and allow to evacuate as per law.
7. Handling and Storage
Precautions for safe handling: Keep away from sources of ignition. Do not handle or store near an open flame, heat, or other sources of ignition. Use only under a chemical fume hood. Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces. Avoid prolonged exposure. Do not empty into drains. Avoid release to the environment.
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Do not leave the material container open. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like Oxidizing Agents, Reducing Agent, Strong bases, Metals, Amines. Hygroscopic. Storage: Below 30C.
8. Exposure Controls/Personal Protection
Airborne Exposure Limits: Contains no substances with occupational exposure limit values.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full-face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.
9. Physical and Chemical Properties
Appearance: Clear colorless fuming liquid.
Odor: Pungent vinegar like.
Odor threshold: Not available.
pH: 1 (10 g/L).
Relative density: 1.49
Boiling point: 72.4C.
Melting point/Freezing point: -15.4C.
Flash Point: >100C
Auto-ignition Temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility (water): Miscible with water.
Viscosity: Not available.
Molecular Formula: C2HF3O2
Molecular Weight: 114.02
10. Stability and Reactivity
Stability: It is stable under ordinary conditions of use and storage.
Hazardous Decomposition Products: It emits carbon oxides and fumes when heated to decomposition.
Hazardous Polymerization: Will not occur.
Incompatibilities: Oxidizing agents, Reducing Agent, Strong bases, Metals, Amines.
Conditions to Avoid: Avoid light, heat, sparks, open flames, and other ignition sources. Contact with incompatible materials.
11. Toxicological Information
Toxicity data:
LD50 Oral - Rat - 200-400 mg/kg.
LD50 Inhalation - Rat - 10 mg/L/2h.
Carcinogenicity: Not expected to be hazardous by IARC, NTP, ACGIH and OSHA criteria.
Mutagenic Effects: No information available
Reproductive Effects: No information available.
Developmental Effects: No information available.
Teratogenicity: No information available.
Causes severe burns by all exposure.
12. Ecological Information
Toxicity to fish: static test LC50 - Danio rerio (zebra fish) - > 999 mg/l - 96 h.
Toxicity to daphnia and other aquatic invertebrates: static test EC50 - Daphnia magna (Water flea) - > 999 mg/l - 48 h.
Persistence and degradability: Persistence is unlikely based on available information.
Mobility in soil: Likely to be mobile.
Results of PBT and vPvB assessment: Not available.
13. Disposal Considerations
Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. Processing use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose of container and unused contents in accordance with law.
14. Transport Information
Department of Transportation DOT USA, TDG Canada & ADR/RID Europe:
UN-No UN 2699
Proper Shipping Name: Trifluoroacetic acid.
Hazard Class 8; Packing Group I.
IMDG/IMO:
UN-No UN 2699
Proper Shipping Name: Trifluoroacetic acid.
Hazard Class 8; Packing Group I.
IATA:
UN-No UN 2699
Proper Shipping Name: Trifluoroacetic acid.
Hazard Class 8; Packing Group I.
15. Regulatory Information
USA:
SARA 311/312 Hazards: Acute Health Hazard; Chronic Health Hazard. See section 2.
California Prop. 65 Components: This product does not contain any chemicals known to the State of California to cause cancer, birth defects, or any other reproductive harm.
Section 16 - Additional Information
European Labeling in Accordance with EC Directives:
H332: Harmful if inhaled.
H314: Causes severe skin burns and eye damage.
H412 Harmful to aquatic life with long lasting effects.
Hazard Symbols:
Xn Harmful.
C Corrosive.
Risk Phrases:
R20 Harmful by inhalation.
R35 Causes severe burns.
R41 Risk of serious damage to eyes.
R53 May cause long-term adverse effects in the aquatic environment.
Disclaimer:
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Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
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