Methyl Folate Calcium or Calcium levomefolate or Vitamin B9 or L-Methylfolate Calcium USP Manufacturers, with SDS GHS MSDS Sheet

Supplier, Manufacturer, Exporter of Methyl Folate Calcium or Calcium levomefolate or Vitamin B9 or L-Methylfolate Calcium or Calcium l-5-Methyltetrahydrofolate USP, Muby Chemicals of Mubychem Group, established in 1976, is the original manufacturers of Specialty Chemicals, Pharmaceutical Excipient, Fragrance Food & Flavor chemicals, Reagent Grade Chemicals, Shale Gas Fracturing Chemicals in India. Mubychem Group has several manufacturing facilities spread across Western India and world wide contacts and toll manufacturers. We are exporting globally to countries like USA, Canada, Europe, UAE, South Africa, Tanzania, Kenya, Egypt, Nigeria, Cameroon, Uganda, Turkey, Mexico, Brazil, Chile, Argentina, Dubai, Korea, Vietnam, Thailand, Malaysia, Indonesia, Australia, China, Germany, France, Italy Portugal, Bangladesh, etc.

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Methyl Folate Calcium or Calcium levomefolate or Vitamin B9 or L-Methylfolate Calcium or Calcium l-5-Methyltetrahydrofolate USP CAS Number 151533-22-1, EINECS EC Number: 691-636-3, Molecular Formula: C20H23CaN7O6, Molecular Weight: 497.52, HS Code 29420090 or 29252900 or 29362910

Specifications, Safety Data Sheet, Manufacturing process details, Wholesale retail buy sell prices, Uses etc available on line in these pages for Methyl Folate Calcium or Calcium levomefolate or Vitamin B9 or L-Methylfolate Calcium or Calcium l-5-Methyltetrahydrofolate USP .

Folic acid supplements may come in different forms such as L-methylfolate. They are used to treat or prevent low folate levels.

General Properties and Specifications of Methyl Folate Calcium or Vitamin B9 or L-Methylfolate Calcium:
Appearance: Off white to yellow color powder.
Assay: 95.0% to 102%
Solubility: Sparingly soluble in hot water (at 95) sparingly soluble in hot alkaline solution (0.1 n NaOH at 95) very slightly soluble or insoluble in most organic solvent.
Identification: The retention time of the major peak of the sample solution correspond to that of the standard solution as obtained in assay.
Heavy metal (as lead): NMT 10ppm.
Calcium on dry basis: 7.00% to 8.50%
Melting Point: Decomposes at 300C.
Storage: Refrigerated. Short term shipping may be ambient.

Calcium l-5-Methyltetrahydrofolate USP Grade Specifications:
C20H23CaN7O6-x H2O
C20H23CaN7O6 (anhydrous) 497.52
N-[4-[[(2-Amino-1,4,5,6,7,8-hexahydro-5-methyl-4-oxo-(6S)-pteridinyl)methyl]amino]benzoyl]-l-glutamic acid, calcium salt (1:1);
N-{4-[[((6S)-2-Amino-1,4,5,6,7,8-hexahydro-5-methyl-4-oxo-6-pteridinyl)methyl]amino]-benzoyl}-l-glutamic acid, calcium salt (1:1) CAS 151533-22-1
UNII: A9R10K3F2F
UNII: 8S95DH25XC

DEFINITION
Calcium l-5-Methyltetrahydrofolate contains NLT 95.0% and NMT 102.0% of calcium 5-methyltetrahydrofolate (C20H23CaN7O), the sum of the l- and d-diastereoisomers, calculated on the anhydrous and solvent-free basis, of which NMT 1.0% corresponds to calcium d-5-methyltetrahydrofolate.

IDENTIFICATION
A. Infrared Absorption
B. Identification Tests—General, Calcium: A 5-mg/mL solution meets the requirements.
C. HPLC

Chloride: To pass the test. --- not more than 0.5%
Boron: NMT 50 µg/g.
Platinum: NMT 10 µg/g.
Arsenic: NMT 1.5 µg/g.
Cadmium: NMT 0.5 µg/g.
Lead: NMT 1.0 µg/g.
Mercury: NMT 1.5 µg/g.
Residual Solvents:
Ethanol: NMT 0.5%
2-Propanol: NMT 0.5%
Related Compounds: To pass the test.
Calcium: To pass the test. --- 7.0%–8.5% on the anhydrous and solvent-free basis.
Packaging and Storage: Store in a tight container, in a cool and dry place.

For Original Monographs of IP Indian Pharmacopoeia EP Ph Eur European Pharmacopoeia BP British Pharmacopoeia USP US Pharmacopoeia FCC Food Grade product, please check with the respective web-pages or books.

MUBY CHEMICALS
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Methyl Folate Calcium or Calcium levomefolate or Vitamin B9 or L-Methylfolate Calcium or Calcium l-5-Methyltetrahydrofolate
SDS, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet 05-Aug-24

Product Name & Other Names: Methyl Folate Calcium or Calcium levomefolate or Vitamin B9 or L-Methylfolate Calcium or Calcium l-5-Methyltetrahydrofolate
CAS No.: 151533-22-1
EINECS EC Code number: 691-636-3
Molecular Weight: 497.52
Chemical Formula: C20H23CaN7O6
Relevant uses and uses advised against (if any): Laboratory Chemicals and Industrial Manufacturing Use.
Supplier: As per letterhead.

GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008

Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
This substance is not classified as dangerous according to Directive 67/548/EEC.

Hazards not otherwise classified (HNOC):
May causes mild skin irritation.
May causes mild eye irritation.

Precautionary statements:
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P262: Do not get in eyes, on skin, or on clothing.
P281: Use personal protective equipment as required.
P302+P352: IF ON SKIN: Wash with plenty of soap and water.
P303+P361+P353: IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+313: If eye irritation persists get medical advice/attention.

Inhalation: Remove to fresh air. If breathing is difficult, give oxygen. Get medical attention.
Ingestion: Never give anything by mouth to an unconscious person. Get medical attention.
Skin Contact: After contact with skin, wash immediately with plenty of water. Gently and thoroughly wash the contaminated skin with running water and non-abrasive soap. Be particularly careful to clean folds, crevices, creases, and groin. Cold water may be used. Cover the irritated skin with an emollient. If irritation persists, seek medical attention. Wash contaminated clothing & Shoes before reusing.
Eye Contact: Check for and remove any contact lenses. Immediately flush your eyes with running water for at least 15 minutes, keeping eyelids open. Cold water may be used. Do not use eye ointment. Seek medical attention.

Fire: Not considered to be a fire hazard.
Explosion: Not considered to be an explosion hazard.
Fire Extinguishing Media: In case of fire, use carbon dioxide, water spray, dry chemical powder or appropriate foam. Avoid Solid water jet.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes. Fire-extinguishing work is done from the windward and a suitable fire-extinguishing method according to the surrounding situation is used. Uninvolved persons should evacuate to a safe place.

Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil or water sources.
Methods and materials used for containment cleanup procedures and Storage:
Small Spill: Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to legal requirements.
Large Spill: Contain spilled material. Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and disposing of it according to legal requirements.

Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Do not leave the material container open. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like oxidizing agents. Storage: Refrigerated. Short term shipping may be ambient.

Airborne Exposure Limits: None established.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full-face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.

Appearance: Off white to yellow color powder.
Odor: Not available.
Odor threshold: Not available.
pH: Not available.
Relative density: Not available.
Melting point/freezing point: Decomposes at 300C.
Initial boiling point and boiling range: Not available.
Flash point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility(ies): Sparingly soluble in hot water (at 95) sparingly soluble in hot alkaline solution (0.1 n NaOH at 95) very slightly soluble or insoluble in most organic solvent.
Viscosity: Not available.
Molecular Weight: 497.52
Chemical Formula: C20H23CaN7O6

Stability: Stable under recommended storage conditions.
Hazardous Decomposition Products: At higher temperatures, substance decomposes into Calcium oxide and Nitrogen oxides, Carbon dioxide and Carbon monoxide and fumes.
Hazardous Polymerization: This substance does not polymerize.
Incompatibilities: Oxidizing agents.
Conditions to Avoid: Oxidizing agents and heat.

Oral LD50 Mouse: Not determined
Oral LD50 Rat: Not determined
Carcinogenicity: No component of this product present at levels greater than or equal to 0.1% is identified as possible or confirmed human carcinogen by IARC, ACGIH, OSHA and NTP.
Mutagenic Effects: Not available.
Developmental Toxicity: Not available.
Reproductive Effects: No information available.

Environmental Fate: No information found.
Environmental Toxicity: No information found.
Persistence and Degradability: No information available.
Mobility: No information available.
Bioaccumulation/ Accumulation: No information available.
Results of PBT and vPvB assessment: No data available for assessment.

13. Disposal Considerations
Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. Processing use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose of containers and unused material in accordance with federal, state, and local requirements.

DOT USA, TDG Canada & ADR/RID Europe: Not dangerous goods.
IMDG/IMO: Not dangerous goods.
IATA/ICAO: Not dangerous goods.

USA:
California Proposition 65: Not listed.
SARA 311/312 Hazards: See section 2.

Disclaimer:
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Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
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