Isopropyl myristate or Isopropyl tetradecanoate or Myristic acid isopropyl ester Manufacturers, with SDS GHS MSDS Sheet

Supplier, Manufacturer, Exporter of Isopropyl myristate or Isopropyl tetradecanoat, Muby Chemicals of Mubychem Group, established in 1976, is the original manufacturers of Specialty Chemicals, Pharmaceutical Excipient, Fragrance Food & Flavor chemicals, Reagent Grade Chemicals, Shale Gas Fracturing Chemicals in India. Mubychem Group has several manufacturing facilities spread across Western India and world wide contacts and toll manufacturers. We are exporting globally to countries like USA, Canada, Europe, UAE, South Africa, Tanzania, Kenya, Egypt, Nigeria, Cameroon, Uganda, Turkey, Mexico, Brazil, Chile, Argentina, Dubai, Korea, Vietnam, Thailand, Malaysia, Indonesia, Australia, China, Germany, France, Italy, Portugal, Bangladesh, etc.

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Isopropyl myristate or Isopropyl tetradecanoate or Myristic acid isopropyl ester: CAS Number: 110-27-0, EINECS EC Number: 203-751-4, Molecular Formula: C17H34O2 or CH3(CH2)12COOCH(CH3)2, Molecular Weight: 270.45, FEMA Number: 3556, HS Code ---**

Specifications, Safety Data Sheet, Manufacturing process details, Wholesale retail buy sell prices, Uses etc available on line in these pages for Isopropyl myristate or Isopropyl tetradecanoate or Myristic acid isopropyl ester.

Isopropyl myristate is a polar emollient and is used in cosmetic and topical medicinal preparations where good absorption into the skin is desired. Isopropyl myristate is being studied as a skin enhancer. Isopropyl myristate was used as oil phase in the preparation of formulations. It was also used as oil/water-type tacrolimus solvent. Isopropyl myristate is also used as a solvent in perfume materials.

General Properties and Specifications of Isopropyl myristate or Isopropyl tetradecanoate or Myristic acid isopropyl ester:
Appearance: Colorless liquid of low viscosity.
Assay: 98.5% minimum.
Melting point: about 3C literature.
Boiling point: about 167C at 9 mmHg literature.
Flash point: >150C.
Relative density: 0.85
Solubility: Soluble in castor oil, cottonseed oil, acetone, chloroform, ethyl acetate, ethanol, toluene, and mineral oil.

Specifications of Isopropyl Myristate USP NF Grade:
C17H34O2 --- 270.46
Tetradecanoic acid, 1-methylethyl ester.
Isopropyl myristate --- 110-27-0.

Isopropyl Myristate consists of esters of isopropyl alcohol and saturated high molecular weight fatty acids, principally myristic acid. It contains not less than 90.0 percent of C17H34O2.

Packaging and storage: Preserve in tight, light-resistant containers.
Identification: To pass the chromatic graphic test.
Specific gravity: between 0.846 and 0.854.
Acid value: not more than 1.
Iodine value: not more than 1.
Saponification value: between 202 and 212.
Refractive index: between 1.432 and 1.436 at 20 .
Residue on ignition: not more than 0.1%.

Specifications of Isopropyl Myristate BP Ph Eur Grade:
C17H34O2 --- 270.5
Action and use: Excipient.

DEFINITION
1-Methylethyl tetradecanoate together with variable amounts of other fatty acid isopropyl esters.
Content: Minimum 90.0 per cent of C17H34O2.

CHARACTERS
Appearance: Clear, colourless, oily liquid.
Solubility: Immiscible with water, miscible with ethanol (96 per cent), with methylene chloride, with fatty oils and with liquid paraffin.
Relative density: About 0.853.

IDENTIFICATION
First identification: B.
Second identification: A, C.
A. Saponification value.
B. Examine the chromatograms obtained in the assay.
Results The principal peak in the chromatogram obtained with the test solution is similar in retention time to the principal peak in the chromatogram obtained with the reference solution.
C. Superpose 2 mL of a 1 g/L solution in ethanol (96 per cent) on a freshly prepared solution of 20 mg of dimethylaminobenzaldehyde in 2 mL of sulfuric acid. After 2 min, a yellowish-red colour appears at the junction of the 2 liquids and gradually becomes red.

TESTS
Appearance of solution: The solution is clear and not more intensely coloured than reference solution.
Dissolve 2.0 g in methanol and dilute to 20 mL with the same solvent.
Refractive index: 1.434 to 1.437.
Viscosity: 5 mPa⋅s to 6 mPa⋅s.
Acid value: Maximum 1.0.
Iodine value: Maximum 1.0.
Saponification value: 202 to 212.
Water: Maximum 0.1 per cent, determined on 5.0 g.
Total ash: Maximum 0.1 per cent, determined on 1.0 g.

For Original Monographs of IP Indian Pharmacopoeia BP British Pharmacopoeia USP US Pharmacopoeia FCC Food Grade product, please check with the respective web-pages or books.

MUBY CHEMICALS
Ambernath Mumbai, Ankleshwar Gujarat, India
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Isopropyl myristate or Isopropyl tetradecanoate SDS Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet 24-Oct-20

Product Name & Other Names: Isopropyl myristate or Isopropyl tetradecanoate or Myristic acid isopropyl ester.
CAS Number: 110-27-0
EINECS EC Code: 203-751-4
Molecular Formula: C17H34O2 or CH3(CH2)12COOCH(CH3)2
Molecular Weight: 270.45
Relevant uses and uses advised against (if any): Industrial Manufacturing.
Suppliers: As per letterhead.

GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Hazard Class and Category Code(s), Regulation (EC) No 1272/2008 (CLP)

Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
This substance is not classified as dangerous according to Directive 67/548/EEC.

Hazards not otherwise classified (HNOC):
May causes mild skin irritation.
May causes mild eye irritation.

Precautionary statements:
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P262: Do not get in eyes, on skin, or on clothing.
P281: Use personal protective equipment as required.
P302+P352: IF ON SKIN: Wash with plenty of soap and water.
P303+P361+P353: IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+313: If eye irritation persists get medical advice/attention.

Product Name & Other Names: Isopropyl myristate or Isopropyl tetradecanoate or Myristic acid isopropyl ester.
CAS Number: 110-27-0
EINECS EC Code: 203-751-4

Skin: Rinse with water. Soap may be used. Seek Medical Aid.
Eyes: Wash eyes with plenty of water for at least 15 minutes, lifting lids occasionally. Seek Medical Aid.
Inhalation: Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Ingestion: If swallowed, induce vomiting immediately after giving two glasses of water. Never give anything by mouth to an unconscious person.

Flammability of the Product: May be combustible at high temperature. May be ignited by heat, sparks or flames. Container explosion may occur under fire conditions or when heated.
Products of Combustion: Oxides of Carbon and Fumes.
Fire Fighting Media and Instructions: Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. Wear self-contained breathing apparatus for firefighting if necessary.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes. Fire-extinguishing work is done from the windward and the suitable fire-extinguishing method according to the surrounding situation is used. Uninvolved persons should evacuate to a safe place.

Personal precautions, protective equipment and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil or water sources.
Methods and materials used for containment Cleanup procedures and Storage:
Small Spill: Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to legal requirements.
Large Spill: Contain spilled material. Do not inhale dust, mist, or gas. Avoid dust/mist formation. Absorb with inert liquid-absorbent material. Use a shovel to put the material into a convenient waste disposal container.

Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. Wash thoroughly after handling. Do not drink, eat or smoke while handling. Avoid contact with skin, eyes and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cool, dry and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Do not leave the material container open. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like oxidizing agents.

Engineering Controls: Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to airborne contaminants below the exposure limit.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Dust deposits on floors and other surfaces may pick up moisture and cause the surfaces to become slippery and present safety hazards. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.

Physical state and appearance: Colorless liquid of low viscosity.
Odor: Not available.
Odor threshold: Not available.
pH: Not available.
Relative density: 0.85
Melting point: about 3C literature.
Boiling Point: 167C at 9 mmHg literature.
Flash point: >150C.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility: Soluble in castor oil, cottonseed oil, acetone, chloroform, ethyl acetate, ethanol, toluene, and mineral oil.
Viscosity: Not available.
Molecular Formula: C17H34O2 or CH3(CH2)12COOCH(CH3)2
Molecular Weight: 270.45

Stability: It is stable in room temperature in closed containers under normal storage & handling.
Conditions of instability: Incompatible materials, Excess heat, light.
Incompatibility with various substances: Avoid high temperatures, sparks, open flames and moisture. Avoid contact with strong oxidizing agents.
Polymerization: Will not occur.
Hazardous decomposition products: Carbon dioxide and carbon monoxide and other hazardous decomposition products formed under fire conditions.

LD50 Oral - Rat - > 5000 mg/kg.
LD50 Dermal - Rabbit - > 5000 mg/kg.
Carcinogenic Effects: Not a reported carcinogen by IARC, NTP, ACGIH, OSHA.
Reproductive toxicity: No data available.
Mutagenic Effects: Not available.
Developmental Toxicity: Not available.

Toxicity to fish: static test LC50 - (Brachydanio rerio): 8400 mg/l - 96 h.
Toxicity to daphnia and other aquatic invertebrates: static test EC50 - Daphnia magna (Water flea) - > 100 mg/l - 48 h.
Do not allow to enter into ground-water, surface water or drains.
Persistence and Degradability: No information available. May not persist as per available information.
Mobility: No information available.
Results of PBT and vPvB assessment: No data available for assessment.

Waste Disposal: Waste must be disposed of in accordance with federal, state and local environmental control regulations.

DOT USA, TDG Canada & ADR/RID Europe: Not dangerous goods.
IATA & IMDG/IMO: Not dangerous goods.

USA Regulations:
SARA 302: No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302.
SARA 313: This material does not contain any chemical components with known CAS numbers that exceed the threshold (De Minimis) reporting levels established by SARA Title III, Section 313.
SARA 311/312 Hazards: No SARA Hazards
California Prop 65: California No Significant Risk Level: None of the chemicals in this product are listed.

Disclaimer:
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Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
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