Cholesterol USP NF BP Ph Eur Grade Manufacturers, with SDS GHS MSDS Sheet |
Supplier, Manufacturer, Exporter of Cholesterol, Muby Chemicals of Mubychem Group, established in 1976, is the original manufacturers of Specialty Chemicals, Pharmaceutical Excipient, Fragrance Food & Flavor chemicals, Reagent Grade Chemicals, Shale Gas Fracturing Chemicals in India. Mubychem Group has several manufacturing facilities spread across Western India and world wide contacts and toll manufacturers. We are exporting globally to countries like USA, Canada, Europe, UAE, South Africa, Tanzania, Kenya, Egypt, Nigeria, Cameroon, Uganda, Turkey, Mexico, Brazil, Chile, Argentina, Dubai, Korea, Vietnam, Thailand, Malaysia, Indonesia, Australia, China, Germany, France, Italy, Portugal, Bangladesh, etc. The products are offered as per required specifications and in correct shape and size in mm or meshs or microns as specified by the buyer. The participating units have one or more accreditations like FDA - cGMP and GLP approval, ISO-9001 Certified, "REACH" Registered, ISO-14001, ISO/IEC 17025, ISO-22000, FSSC 22000, ISO 45001, Kosher Certified, Halal Certified, HACCP, FSSAI. We offer Commercial Pure & IP BP EP Ph Eur USP NF JP FCC Food Grade Analytical Reagent Grades of Chemicals |
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Cholesterol CAS Number 57-88-5, EINECS EC Number: 200-353-2, Molecular Formula: C27H46O, Molecular Weight: 386.65, HS Code 29061310
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SDS MSDS Sheet of Cholesterol Manufacturers
Cholesterol
USP NF BP Ph Eur Grade Suppliers
Cholesterol is a waxy, fat-like substance that your body needs for good health, but in the right amounts. Unhealthy levels of cholesterol can lead to a condition called high blood cholesterol.
General Properties and Specifications of Cholesterol:
Appearance: White crystalline compound.
Odor: Odorless.
Solubility of 10% solution in Diethylether: Almost clear colorless.
Solubility of 10% solution in Chloroform: Clear colorless.
Assay (GC): 99% minimum as total steroid.
Loss on drying: 0.1% maximum.
Sulphated Ash: 0.1% maximum.
Homogeneity by TLC: Passes test.
Suitability for Cell Culture: Passes.
Bacterial Endotoxin Test (BET) (EU/mg = IU/mg): <0.05 EU/mg.
Relative Density: about 1.07
Melting Point: 147C to 150C.
Boiling Point: 360C decomposes.
Solubility: Negligible solubility in water. Moderately soluble in hot alcohol. Soluble in benzene, oils, fats.
Storage: 0C to 4C (Refrigerate).
Cholesterol USP NF Grade Specifications:
C27H46O --- 386.65
Cholest-5-en-3-ol, (3β)-;
Cholest-5-en-3β-ol CAS 57-88-5
UNII: 97C5T2UQ7J
DEFINITION
Cholesterol is a steroid alcohol containing NLT 95.0% and NMT 102.0% of cholest-5-en-3β-ol (C27H46O), calculated on the dried basis. It may contain suitable stabilizers.
IDENTIFICATION
A. Infrared Absorption.
B. It meets the requirements of the test for Optical Rotation, Specific Rotation.
C. It meets the requirements of the test for Melting Range or Temperature.
Residue on Ignition: NMT 0.1%
Limit of Related Sterols and Other Organic Impurities: To pass the test.
Total impurities including related sterols NMT 5%.
Melting Range or Temperature: 147C to 150C.
Optical Rotation Specific Rotation:
Sample solution: 20 mg/mL, undried, in dioxane.
Acceptance criteria: −34° to −38°
Acidity: To pass the test.
Loss on Drying: Dry under vacuum at 60C for 4 h. Acceptance criteria: NMT 0.3%
Solubility in Alcohol: Dissolve the 500 mg Sample in 50 mL of warm alcohol in a stoppered flask or cylinder, and allow to stand at room temperature for 2 h. No deposit or turbidity is formed.
Cholesterol BP Ph Eur Grade Specifications:
C27H46O --- 386.7 CAS 57-88-5
Action and use: Excipient.
DEFINITION
Cholest-5-en-3β-ol.
Content:
- cholesterol: minimum 95.0 per cent (dried substance);
- total sterols: 97.0 per cent to 103.0 per cent (dried substance).
CHARACTERS
Appearance: White or almost white, crystalline powder.
Solubility: Practically insoluble in water, sparingly soluble in acetone and in ethanol (96 per cent).
It is sensitive to light.
IDENTIFICATION
A. Melting point: 147C to 150C.
B. Thin-layer chromatography.
C. Dissolve about 5 mg in 2 mL of methylene chloride. Add 1 mL of acetic anhydride, 0.01 mL of sulfuric acid and shake. A pink colour is produced which rapidly changes to red, then to blue and finally to brilliant green.
Solubility in ethanol (96 per cent): In a stoppered flask, dissolve 0.5 g in 50 mL of ethanol (96 per cent) at 50C. Allow to stand for 2 h. No deposit or turbidity is formed.
Acidity: To pass the test.
Loss on drying: Maximum 0.3 per cent, determined on 1.000 g by drying in vacuo at 60C for 4 h.
Sulfated ash: Maximum 0.1 per cent, determined on 1.0 g.
For Original Monographs of IP Indian Pharmacopoeia BP British Pharmacopoeia USP US Pharmacopoeia FCC Food Grade product, please check with the respective web-pages or books.
We also manufacture and supply as under:
Medium-chain Triglycerides MCT Oil
Manufacturers:
MUBY CHEMICALS
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Last
19 April, 2024
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Cholesterol SDS, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet 16-Dec-23
Section 1: Chemical Product and Company Identification
Product Name & Other Names: Cholesterol.
CAS Number: 57-88-5
EINECS EC Code: 200-353-2
Molecular Formula: C27H46O
Molecular Weight: 386.65
Relevant uses and uses advised against (if any): Industrial Manufacturing.
Suppliers: As per letterhead.
Section 2: Hazards Identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Hazard Class and Category Code(s), Regulation (EC) No 1272/2008 (CLP)
Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
This substance is not classified as dangerous according to Directive 67/548/EEC.
Labeling as per GHS and Regulation EC 1272/2008 (CLP) & GHS
GHS Label Elements NONE |
Signal Word: None
Hazards not otherwise classified (HNOC):
May causes mild skin irritation.
May causes mild eye irritation.
Precautionary statements:
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P262: Do not get in eyes, on skin, or on clothing.
P281: Use personal protective equipment as required.
P302+P352 - IF ON SKIN: Wash with plenty of soap and water.
P304 + P340 - IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+313: If eye irritation persists get medical advice/attention.
Section 3: Composition and Information on Ingredients
Product Name & Other Names: Cholesterol.
CAS Number: 57-88-5
EINECS EC Code: 200-353-2
Section 4: First Aid Measures
Always seek medical advice after the first aid treatment.
Skin: Rinse with water. Soap may be used. Seek Medical Aid.
Eyes: Wash eyes with plenty of water for at least 15 minutes, lifting lids occasionally. Seek Medical Aid.
Inhalation: Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Ingestion: If swallowed, induce vomiting immediately after giving two glasses of water. Never give anything by mouth to an unconscious person.
Section 5: Fire and Explosion Data
Flammability of the Product: Non-flammable.
Products of Combustion: Oxides of Carbon and fumes.
Fire Fighting Media and Instructions: Use water spray, alcohol-resistant foam, dry chemical, or carbon dioxide. Wear self-contained breathing apparatus for firefighting if necessary.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes. Fire-extinguishing work is done from the windward and a suitable fire-extinguishing method according to the surrounding situation is used. Uninvolved persons should evacuate to a safe place.
Section 6: Accidental Release Measures
Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment cleanup procedures and Storage:
Small Spill: Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to legal requirements.
Large Spill: Contain spilled material. Do not let the product enter drains. Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and allow evacuating as per law.
Section 7: Handling and Storage
Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. In case of insufficient ventilation, wear suitable respiratory equipment. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like strong oxidizing agents.
Section 8: Exposure Controls/Personal Protection
Engineering Controls: Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits. If user operations generate dust, fume, or mist, use ventilation to keep exposure to airborne contaminants low.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full-face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.
Section 9: Physical and Chemical Properties
Physical state and appearance: White crystalline compound.
Odor: Odorless.
Odor threshold: Not applicable.
pH: Not available.
Relative density: about 1.07
Melting point: 147C to 150C.
Initial boiling point and boiling range: 360C decomposes.
Flash point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility: Practically insoluble in water.
Viscosity: Not available.
Molecular Formula: C27H46O
Molecular Weight: 386.65
Section 10: Stability and Reactivity Data
Stability: It is stable under recommended temperature in closed containers under normal storage & handling.
Conditions of instability: Incompatible materials.
Incompatibility with various substances: Avoid high temperatures, sparks, open flames, and moisture. Avoid contact with strong oxidizing agents.
Polymerization: Will not occur.
Section 11: Toxicological Information
LD50 Oral, Rat: > 2000 mg/kg.
LD50 Dermal, Rat: > 2000 mg/kg.
Carcinogenicity: No component of this product present at levels greater than or equal to 0.1% is identified as possible or confirmed human carcinogen by IARC, ACGIH, OSHA and NTP.
Teratogenic Effects: Not available.
Mutagenic Effects: Not available.
Developmental Toxicity: Not available.
Reproductive Effects: No information available.
Section 12: Ecological Information
Toxicity: No information available.
Persistence and Degradability: No information available.
Mobility: No information available.
Bioaccumulation/ Accumulation: Readily biodegradable. Expected to be unlikely to bioaccumulate.
Results of PBT and vPvB assessment: No data available for assessment.
The product is not classified as environmentally hazardous. However, this does not exclude the possibility that large or frequent spills can have a harmful or damaging effect on the environment.
Section 13: Disposal Considerations
Waste Disposal: Waste must be disposed of in accordance with federal, state, and local environmental control regulations.
Section 14: Transport Information
DOT USA, TDG Canada & ADR/RID Europe: Not dangerous goods
IMDG/IMO: Not dangerous goods
IATA: Not dangerous goods.
Section 15: Other Regulatory Information
USA Regulations:
OSHA: None of the chemicals in this product are considered highly hazardous by OSHA.
California Prop 65: California No Significant Risk Level: None of the chemicals in this product are listed.
Disclaimer:
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Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
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