Dimeticone BP Ph Eur EP Dimethicone USP NF Grade Manufacturers, with SDS GHS MSDS Sheet
Supplier, Manufacturer, Exporter of Dimeticone or Dimethicone, Muby Chemicals of Mubychem Group, established in 1976, is the original manufacturers of Specialty Chemicals, Pharmaceutical Excipient, Fragrance Food & Flavor chemicals, Reagent Grade Chemicals, Shale Gas Fracturing Chemicals in India. Mubychem Group has several manufacturing facilities spread across Western India and world wide contacts and toll manufacturers. We are exporting globally to countries like USA, Canada, Europe, UAE, South Africa, Tanzania, Kenya, Egypt, Nigeria, Cameroon, Uganda, Turkey, Mexico, Brazil, Chile, Peru, Argentina, Dubai, Korea, Vietnam, Thailand, Malaysia, Indonesia, Australia, China, Germany, France, Italy, Portugal etc.
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Dimeticone or Dimethicone: CAS Number: 9006-65-9 or 9006-75-9 or 9016-00-6 or 63148-62-9, EINECS EC Number: yyyyy, Molecular Formula: yyyyy, Molecular Weight: yyyyy, HS Code ---**
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SDS MSDS Sheet of Dimeticone or Dimethicone Manufacturers
Spanish Fabricantes de dimeticona
Portugal Dimeticona fabricantes
Dimeticone BP Ph Eur EP Dimethicone USP NF Suppliers
Dimeticone BP Ph Eur Grade
Ph Eur --- CAS 9006-75-9
Action and use: Antifoaming agent; water repellent. When dimethicone is demanded, Dimeticone shall be supplied.
Poly(dimethylsiloxane) obtained by hydrolysis and polycondensation of dichlorodimethylsilane and chlorotrimethylsilane. Different grades of dimeticone exist which are distinguished by a number indicating the nominal kinematic viscosity placed after the name.
Their degree of polymerisation (n = 20 to 400) is such that their kinematic viscosities are nominally between 20 mm2·s-1 and 1300 mm2·s-1.
Dimeticones with a nominal viscosity of 50 mm2·s-1 or lower are intended for external use only.
Appearance: Clear, colourless liquid of various viscosities.
Solubility: Practically insoluble in water, very slightly soluble or practically insoluble in anhydrous ethanol, miscible with ethyl acetate, with methyl ethyl ketone and with toluene.
A. It is identified by its kinematic viscosity at 25C (see Tests).
B. Infrared absorption spectrophotometry.
C. Heat 0.5 g in a test-tube over a small flame until white fumes begin to appear. Invert the tube over a 2nd tube containing 1 ml of a 1 g/l solution of chromotropic acid sodium salt in sulphuric acid so that the fumes reach the solution. Shake the 2nd tube for about 10 s and heat on a water-bath for 5 min. The solution is violet.
D. In a platinum crucible, prepare the sulphated ash using 50 mg. The residue is a white powder that gives the reaction of silicates.
Acidity: To 2.0 g add 25 ml of a mixture of equal volumes of anhydrous ethanol and ether, previously neutralised to 0.2 ml of bromothymol blue solution and shake. Not more than 0.15 ml of 0.01 M sodium hydroxide is required to change the colour of the solution to blue.
Viscosity: 90 per cent to 110 per cent of the nominal kinematic viscosity stated on the label, determined at 25C.
Mineral oils: Place 2 g in a test-tube and examine in ultraviolet light at 365 nm. The fluorescence is not more intense than that of a solution containing 0.1 ppm of quinine sulphate in 0.005 M sulphuric acid examined in the same conditions.
Phenylated compounds: Dissolve 5.0 g with shaking in 10 ml of cyclohexane. At wavelengths from 250 nm to 270 nm, the absorbance of the solution is not greater than 0.2.
Heavy metals: Maximum 5 ppm.
Volatile matter: Maximum 0.3 per cent, for dimeticones with a nominal viscosity greater than 50 mm2·s-1, determined on 1.00 g by heating in an oven at 150 °C for 2 h. Carry out the test using a dish 60 mm in diameter and 10 mm deep.
Dimeticone EP is also supplied.
Dimethicone USP Grade
-(Trimethylsilyl)- -methylpoly[oxy(dimethylsilylene)] [CAS 9006-65-9].
Dimethicone is a mixture of fully methylated linear siloxane polymers containing repeating units of the formula: [–(CH3)2SiO–]n stabilized with trimethylsiloxy end-blocking units of the formula: [(CH3)3SiO–] wherein n has an average value such that the corresponding nominal viscosity is in a discrete range between 20 and 30,000 centistokes. It contains not less than 97.0 percent and not more than 103.0 percent of polydimethylsiloxane ([–(CH3)2SiO–]n). The requirements for viscosity, specific gravity, refractive index, and loss on heating differ for the several types of Dimethicone, as set forth in the accompanying table.
Labeling: Label it to indicate its nominal viscosity value. Dimethicone intended for use in coating containers that come in contact with articles for parenteral use is so labeled.
Identification: Its IR absorption spectrum, obtained as directed in the Assay, exhibits maxima only at the same wavelengths as that of USP Polydimethylsiloxane RS, obtained as directed in the Assay.
Specific gravity: within the limits specified in the accompanying table.
Viscosity: Determine the viscosity of Dimethicone having a nominal viscosity of less than 1000 centistokes at 25 ± 0.1 , using a capillary viscosimeter. Determine the viscosity of Dimethicone having a nominal viscosity of 1000 centistokes or greater at 25 ± 0.1 , using a rotational viscosimeter. The viscosity is within the limits specified in the accompanying table.
Refractive index: within the limits specified in the accompanying table.
Acidity: Dissolve 15.0 g in a mixture of 15 mL of toluene and 15 mL of butyl alcohol, previously neutralized to bromophenol blue and titrate with 0.050 N alcoholic potassium hydroxide to a bromophenol blue endpoint: not more than 0.10 mL is required.
Loss on heating: Preheat an open aluminum vessel (60 mm in diameter and 10 mm high) at 150C for 30 minutes, and allow to cool to room temperature. Tare the vessel, transfer to it about 1 g of Dimethicone, accurately weighed, heat at 150C in a circulating air oven for 2 hours, and allow to come to room temperature in a desiccator before weighing: it loses not more than the maximum percentage of its weight specified in the accompanying table.
Heavy metals: To pass the test (5 microgm per g).
Bacterial endotoxins: To pass the test: equivalent to not more than 10 Endotoxin Units per mL of the Dimethicone taken.
Nominal Viscosity &
Loss on heating
viscosity(centistokes) Specific gravity Refractive index (centistokes) Min. to Max. Min. to Max. Min. to Max. 020 ------ Max. 20.0 18 to 22 0.946 to 0.954 1.3980 to 1.4020 050 ------ Max. 2.0 47.5 to 52.5 0.955 to 0.965 1.4005 to 1.4045 100 ------ Max. 0.3 95 to 105 0.962 to 0.970 1.4005 to 1.4045 200 ------ Max. 0.3 190 to 220 0.964 to 0.972 1.4013 to 1.4053 350 ------ Max. 0.3 332.5 to 367.5 0.965 to 0.973 1.4013 to 1.4053 500 ------ Max. 0.3 475 to 525 0.967 to 0.975 1.4013 to 1.4053 1000 ------ Max. 0.3 950 to 1050 0.967 to 0.975 1.4013 to 1.4053 12,500 ------ Max. 2.0 11,875 to 13,125 -- -- 1.4015 to 1.4055 30,000 ------ Max. 2.0 27,000 to 33,000 0.969 to 0.977 1.4010 to 1.4100
For Original Monographs of IP Indian Pharmacopoeia BP British Pharmacopoeia USP US Pharmacopoeia FCC Food Grade product, please check with the respective web-pages or books.
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Last : 19 February, 2023
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Dimeticone or Dimethicone SDS, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet 16-Oct-20
Section 1: Chemical Product and Company Identification
Product Name & Other Names: Dimeticone or Dimethicone or Poly(dimethylsiloxane)
CAS Number: 9006-75-9 or 9016-00-6 or 63148-62-9
EINECS EC Code: Not available.
Recommended usage: Industrial Manufacturing.
Suppliers: As per letterhead.
Section 2: Hazards Identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Hazard Class and Category Code(s), Regulation (EC) No 1272/2008 (CLP)
Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
This substance is not classified as dangerous according to Directive 67/548/EEC.
Labeling Regulation as per GHS & EC 1272/2008 (CLP) & GHS
GHS Label Elements
Signal Word: None
Hazards not otherwise classified (HNOC):
May causes mild skin irritation.
May causes mild eye irritation.
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P262: Do not get in eyes, on skin, or on clothing.
P281: Use personal protective equipment as required.
P302+P352 - IF ON SKIN: Wash with plenty of soap and water.
P303+P361+P353 - IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
P304 + P340 - IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+313: If eye irritation persists get medical advice/attention.
Section 3: Composition and Information on Ingredients
Product Name & Other Names: Dimeticone or Dimethicone or Poly(dimethylsiloxane)
CAS Number: 9006-75-9
Section 4: First Aid Measures
Always seek medical advice after the first aid treatment.
Skin: Rinse with water. Soap may be used. Seek Medical Aid.
Eyes: Wash eyes with plenty of water for at least 15 minutes, lifting lids occasionally. Seek Medical Aid.
Inhalation: Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Ingestion: If swallowed, induce vomiting immediately after giving two glasses of water. Never give anything by mouth to an unconscious person.
Section 5: Fire and Explosion Data
Flammability of the Product: It is flammable on heating.
Products of Combustion: Oxides of Carbon, Silicone, and fumes.
Fire Fighting Media and Instructions: Use water spray, alcohol-resistant foam, dry chemical, or carbon dioxide. Wear self-contained breathing apparatus for firefighting if necessary.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes.
Section 6: Accidental Release Measures
Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Ensure adequate ventilation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil or water sources.
Methods and materials used for containment Cleanup procedures and Storage:
Small Spill: Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to legal requirements.
Large Spill: Do not inhale vapors, mist, or gas. Avoid dust formation. Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g. sand, earth, diatomaceous earth, vermiculite). Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and allow to evacuate as per law.
Section 7: Handling and Storage
Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Do not leave the material container open. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like oxidizing agents, acids.
Section 8: Exposure Controls/Personal Protection
Engineering Controls: Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits. If user operations generate dust, fume, or mist, use ventilation to keep exposure to airborne contaminants below the exposure limit.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Dust deposits on floors and other surfaces may pick up moisture and cause the surfaces to become slippery and present safety hazards. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.
Section 9: Physical and Chemical Properties
Physical state and appearance: Clear liquid.
Odor threshold: Not available.
pH: Not available.
Relative density: 0.94 to 0.97
Melting point/freezing point: Not available.
Initial boiling point and boiling range: Not available.
Flash point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility: Soluble in water.
Viscosity: Not available.
Section 10: Stability and Reactivity Data
Stability: It is stable in room temperature in closed containers under normal storage & handling.
Conditions of instability: Incompatible materials, Heat.
Incompatibility with various substances: Avoid high temperatures, sparks, open flames, and moisture. Avoid contact with strong oxidizing agents, acids, and bases.
Polymerization: Will not occur.
Section 11: Toxicological Information
LD50 Oral - Rat - >1000 mg/kg
Carcinogenic Effects: Not a reported carcinogen by IARC, NTP, ACGIH, OSHA.
Mutagenic Effects: Not available.
Developmental Toxicity: Not available.
Reproductive Effects: No information available.
Section 12: Ecological Information
Toxicity to fish: LC50 - Oncorhynchus mykiss (rainbow trout) - > 10,000 mg/l - 96 h.
BOD5 and COD: Not available.
Products of Biodegradation: The product itself and its products of degradation are not toxic.
Persistence and Degradability: No information available.
Mobility: No information available.
Bioaccumulation/ Accumulation: No information available.
Results of PBT and vPvB assessment: No data available for assessment.
Section 13: Disposal Considerations
Waste Disposal: Waste must be disposed of in accordance with federal, state, and local environmental control regulations.
Section 14: Transport Information
DOT USA: Not dangerous goods
IMDG: Not dangerous goods
IATA: Not dangerous goods
ADR/RID Europe: Not dangerous goods.
Section 15: Other Regulatory Information
USA Regulations:Section 16 - Additional Information
OSHA: None of the chemicals in this product are considered highly hazardous by OSHA.
California Prop 65: California No Significant Risk Level: None of the chemicals in this product are listed.
SARA 311/312 Hazards: See section 2.
Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.