Magnesium Gluconate EP BP Ph Eur USP & Commercial Pure Analytical Reagent FCC Food Grade Manufacturers, with SDS MSDS Sheet

Supplier, Manufacturer, Exporter of Magnesium Gluconate EP BP Ph Eur USP Commercial Pure Analytical Reagent FCC Food Grade, Muby Chemicals of Mubychem Group, established in 1976, is the original manufacturers of Specialty Chemicals, Pharmaceutical Excipient, Fragrance Food & Flavor chemicals, Reagent Grade Chemicals, Shale Gas Fracturing Chemicals in India. Mubychem Group has several manufacturing facilities spread across Western India and world wide contacts and toll manufacturers. We are exporting globally to countries like USA, Canada, Europe, UAE, South Africa, Tanzania, Kenya, Egypt, Nigeria, Cameroon, Uganda, Turkey, Mexico, Brazil, Chile, Argentina, Dubai, Korea, Vietnam, Thailand, Malaysia, Indonesia, Australia, China, Germany, France, Italy, Portugal, Bangladesh, etc.

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Magnesium Gluconate CAS Number 3632-91-5 for Anhydrous and 59625-89-7 for hydrate, EINECS EC Number 222-848-2, HS Code ---**; Molecular Weight C12H22MgO14, Molecular Formula: 414.6

Specifications, Safety Data Sheet, Manufacturing process details, Wholesale retail buy sell prices, Uses etc available on line in these pages for Magnesium Gluconate.

Magnesium gluconate is a is the magnesium salt of gluconic acid. Magnesium gluconate shows the highest level of bioavailability of any magnesium salt and is recommended as the optimal salt for human supplementation. It has E number "E580".

Magnesium Gluconate BP Ph Eur Grade Specifications
C12H22MgO14,xH2O -- 414.6 -- CAS 3632-91-5 (anhydrous)

CHARACTERS
Appearance: White or almost white, amorphous, hygroscopic, crystalline or granular powder.
Solubility: Freely soluble in water, slightly soluble in ethanol (96 per cent), very slightly soluble in methylene chloride.

IDENTIFICATION
A. Thin-layer chromatography.
B. To 10 ml of solution S (see Tests) add 3 ml of ammonium chloride solution. A slight opalescence may be observed. Add 10 ml of disodium hydrogen phosphate solution. A white precipitate is formed that does not dissolve upon the addition of 2 ml of dilute ammonia.

TESTS
Solution S: Dissolve 1.0 g in water R and dilute to 50 ml with the same solvent.
Appearance of solution: Solution S is clear (2.2.1) and not more intensely coloured than reference solution Y7 (2.2.2, Method II).
Sucrose and reducing sugars: Dissolve 0.5 g in a mixture of 2 ml of hydrochloric acid R1 and 10 ml of water R. Boil for 5 min, allow to cool, add 10 ml of sodium carbonate solution R and allow to stand for 10 min. Dilute to 25 ml with water and filter. To 5 ml of the filtrate add 2 ml of cupri-tartaric solution and boil for 1 min. Allow to stand for 2 min. No red precipitate is formed.
Chlorides: Maximum 500 ppm.
Sulphates: Maximum 500 ppm.
Heavy metals: Maximum 10 ppm.
Water: Maximum 12.0 per cent, determined on 80 mg.
Microbial contamination: Total viable aerobic count (2.6.12) not more than 103 micro-organisms per gram, determined by plate count.

Magnesium Gluconate USP Grade Specifications
C12H22MgO14xH2O -- (anhydrous) 414.60
D-Gluconic acid, magnesium salt (2:1), hydrate.
Magnesium D-gluconate (1:2) hydrate.
Magnesium D-gluconate (1:2) dihydrate 450.64 [CAS 59625-89-7].
Anhydrous [CAS 3632-91-5].

Magnesium Gluconate contains not less than 98.0 percent and not more than 102.0 percent of C12H22MgO14, calculated on the anhydrous basis.

Identification—
A: A solution (1 in 10) responds to the tests for Magnesium.
B: Chromatographic plate test.
pH: between 6.0 and 7.8, in a solution (1 in 20).
Water: between 3.0% and 12.0%.
Chloride: A 1.0-g portion shows no more chloride than corresponds to 0.70 mL of 0.020 N hydrochloric acid (0.05%).
Sulfate: A 2.0-g portion shows no more sulfate than corresponds to 1.0 mL of 0.020 N sulfuric acid (0.05%).
Heavy metals: the limit is 0.002%.
Reducing substances: the limit is 1.0%.

Magnesium Gluconate FCC Food Grade
[CH2OH(CHOH)4COO]2Mg
C12H22MgO14 Formula Weight, anhydrous 414.60
C12H22MgO14·2H2O Formula Weight, dihydrate 450.63
INS: 580 CAS: anhydrous [CAS 3632-91-5]
CAS: dihydrate [CAS 59625-89-7]

DESCRIPTION
Magnesium Gluconate occurs as a white to off white powder or granulate. It is anhydrous, the dihydrate, or a mixture of both. It is very soluble in water and is sparingly soluble in alcohol. It is insoluble in ether.

REQUIREMENTS
Identification
A. A 1:20 aqueous solution gives positive tests for Magnesium.
B. Chromatography Test.
Assay: Not less than 98.0% and not more than 102.0% of C12H22MgO14, calculated on the anhydrous basis.
Chloride: Not more than 0.05%.
Lead: Not more than 2 mg/kg.
Reducing Substances: Not more than 1.0%.
Sulfate: Not more than 0.05%.
Water: Between 3.0% and 12.0%.

For Original Monographs of IP Indian Pharmacopoeia BP British Pharmacopoeia USP US Pharmacopoeia FCC Food Grade product, please check with the respective web-pages or books.

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Magnesium Gluconate SDS, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet 26-Oct-20

Product Name & Other Names: Magnesium gluconate or D-Gluconic acid, magnesium salt (2:1) or Glucomag or Glucosium or Menesia.
Chemical Formula: C12H22MgO14 · xH2O
Molecular Weight: 414.6
CAS Number: 3632-91-5
EINECS EC Code: 222-848-2
Relevant uses and uses advised against (if any): Industrial Manufacturing.
Suppliers: As per letterhead.

GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008

Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
This substance is not classified as dangerous according to Directive 67/548/EEC.

Hazards not otherwise classified (HNOC):
May causes mild skin irritation.
May causes mild eye irritation.

Precautionary statements:
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P262: Do not get in eyes, on skin, or on clothing.
P281: Use personal protective equipment as required.
P302+P352: IF ON SKIN: Wash with plenty of soap and water.
P303+P361+P353: IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Product Name & Other Names: Magnesium gluconate or D-Gluconic acid, magnesium salt (2:1) or Glucomag or Glucosium or Menesia.
CAS Number: 3632-91-5
EINECS EC Code: 222-848-2

Skin: Rinse with water. Soap may be used. Seek Medical Aid.
Eyes: Wash eyes with plenty of water for at least 15 minutes, lifting lids occasionally. Seek Medical Aid.
Inhalation: Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Ingestion: If swallowed, induce vomiting immediately after giving two glasses of water. Never give anything by mouth to an unconscious person.
Notes to Physician: Treat symptomatically.

Flammability of the Product: Non-flammable.
Auto-Ignition Temperature: Not applicable.
Flash Points: Not applicable.
Flammable Limits: Not applicable.
Products of Combustion: Magnesium oxide, Fumes and Oxides of carbon.
Fire Fighting Media and Instructions: Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes. Fire-extinguishing work is done from the windward and the suitable fire-extinguishing method according to the surrounding situation is used. Uninvolved persons should evacuate to a safe place.

Personal precautions, protective equipment, and emergency procedures: Ventilate area of leak or spill. Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment Cleanup procedures and Storage:
Small Spill: Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to legal requirements.
Large Spill: Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g. sand, earth, diatomaceous earth, vermiculite). Vacuum or sweep-up and remove to an approved disposal container. Finish cleaning by spreading water on the contaminated surface and allow to evacuate as per law.

Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. In case of insufficient ventilation, wear suitable respiratory equipment. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like strong oxidizing agents, bases, amines, reducing agents, acids, acid anhydrides.

Engineering Controls: Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits. If user operations generate dust, fume, or mist, use ventilation to keep exposure to airborne contaminants below the exposure limit.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Dust deposits on floors and other surfaces may pick up moisture and cause the surfaces to become slippery and present safety hazards. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.

Physical state and appearance: Solid white to off-white powder or granules.
Odor: Odorless.
Odor threshold: Not available.
pH: Not available.
Relative density: Not available.
Melting point/freezing point: Not available.
Initial boiling point and boiling range: Not available.
Flash point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility: Soluble in water.
Viscosity: Not available.
Chemical Formula: C12H22MgO14 · xH2O
Molecular Weight: 414.6

Stability: It is stable.
Conditions of instability: Incompatible materials
Incompatibility with various substances: Heat, light, strong oxidizing agents, bases, amines, reducing agents, acids, acid anhydrides.
Polymerization: Will not occur.

Toxicity to Animals: LD50 Intravenous - mouse - 321 mg/kg
Carcinogenicity: No component of this product present at levels greater than or equal to 0.1% is identified as possible or confirmed human carcinogen by IARC, ACGIH, OSHA and NTP.
Mutagenic Effects: Not available.
Teratogenic Effects: Not available.
Developmental Toxicity: Not available.
Reproductive Effects: No information available.

Toxicity Data: No information available.
Persistence and Degradability: No information available.
Mobility: No information available.
Bioaccumulation/ Accumulation: No information available.
Results of PBT and vPvB assessment: No data available for assessment.

Waste Disposal: Waste must be disposed of in accordance with federal, state, and local environmental control regulations.

DOT USA, TDG Canada & ADR/RID Europe: Not dangerous goods
IMDG/IMO: Not dangerous goods
IATA: Not dangerous goods.

USA Federal and State Regulations:
SARA 302: No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302.
SARA 313: This material does not contain any chemical components with known CAS numbers that exceed the threshold (De Minimis) reporting levels established by SARA Title III, Section 313.
SARA 311/312 Hazards: No SARA Hazards
California Prop. 65 Components: This product does not contain any chemicals known to State of California to cause cancer, birth defects, or any other reproductive harm.

DISCLAIMER: The information and recommendations set forth herein (hereinafter "Information") are presented in good faith and believed correct as of the date hereof. It is compiled from various sources and it is not necessarily all inclusive nor fully adequate in every circumstance. In addition, these suggestions should not be confused with nor followed in violation of applicable laws, regulations, rules or insurance requirements applicable. This MSDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. Individuals receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose.

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