Sucralose or Trichlorosucrose BP Ph Eur USP NF FCC Food Grade Manufacturers, with SDS GHS MSDS Sheet
Supplier, Manufacturer, Exporter of Sucralose or Trichlorosucrose, Muby Chemicals of Mubychem Group, established in 1976, is the original manufacturers of Specialty Chemicals, Pharmaceutical Excipient, Fragrance Food & Flavor chemicals, Reagent Grade Chemicals, Shale Gas Fracturing Chemicals in India. Mubychem Group has several manufacturing facilities spread across Western India and world wide contacts and toll manufacturers. We are exporting globally to countries like USA, Canada, Europe, UAE, South Africa, Tanzania, Kenya, Egypt, Nigeria, Cameroon, Uganda, Turkey, Mexico, Brazil, Chile, Argentina, Dubai, Korea, Vietnam, Thailand, Malaysia, Indonesia, Australia, China, Germany, France, Italy, Portugal etc.
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Sucralose or Trichlorosucrose: CAS Number: 56038-13-2, EINECS EC Number: 259-952-2, Molecular Formula: C12H19Cl3O8, Molecular Weight: 397.64, HS Code ---**
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SDS MSDS Sheet of Sucralose or Trichlorosucrose Manufacturers
Trichlorosucrose BP Ph Eur USP NF FCC Food Grade Pure Suppliers
Sucralose or Trichlorosucrose is an artificial sweetener and sugar substitute. The majority of ingested sucralose is not broken down by the body, so it is non-caloric. In the European Union, it is also known under the E number E955. Sucralose is about 320 to 1,000 times sweeter than sucrose, three times as sweet as aspartame and twice as sweet as sodium saccharin. Sucralose is used in many food and beverage products because it is a no-calorie sweetener, does not promote dental cavities, is safe for consumption by diabetics and nondiabetics and does not affect insulin levels. Sucralose is used in products such as candy, breakfast bars and soft drinks. It is also used in canned fruits wherein water and sucralose take the place of much higher calorie corn syrup-based additives.
Sucralose FCC Food Grade Specifications:
C12H19Cl3O8 Formula wt 397.64
INS: 955 CAS 56038-13-2]
Sucralose occurs as a white to off white, crystalline powder. It is freely soluble in water, in methanol, and in alcohol, and is slightly soluble in ethyl acetate.
Function: Nonnutritive sweetener; flavor enhancer.
A. The infrared absorption spectrum of a potassium bromide dispersion of the sample exhibits relative maxima at the same wavelengths as those of a similar preparation of Sucralose Standard for analytical use.
B. The retention time of the major peak (excluding the solvent peak) in the liquid chromatogram of the Sample Preparation is the same as that of the Standard Preparation obtained in the Assay.
C. The Rf value of the major spot in the thin-layer chromatogram of the Test Preparation is the same as that of the Standard Preparation obtained in the test for Related Substance.
Assay: Not less than 98.0% and not more than 102.0% of C12H19Cl3O8, calculated on the anhydrous basis.
Hydrolysis Products: Passes test.
Lead: Not more than 1 mg/kg.
Methanol: Not more than 0.1%.
Optical (Specific) Rotation: Between +84.0° and +87.5°, calculated on the anhydrous basis.
Related Substances: Passes test.
Residue on Ignition: Not more than 0.7%.
Water: Not more than 2.0%.
Sucralose USP NF Grade Specifications:
C12H19Cl3O8 --- 397.64
1,6-Dichloro-1,6-dideoxy- -D-fructofuranosyl-4-chloro-4-deoxy- -D-galactopyranoside.
1',4,6'-Trichlorogalactosucrose --- [CAS 56038-13-2].
Sucralose contains not less than 98.0 percent and not more than 102.0 percent of C12H19Cl3O8, calculated on the anhydrous basis.
Packaging and storage: Preserve in well-closed containers, in a cool, dry place, at a temperature not exceeding 21C.
A: Infrared Absorption 197K.
B: The retention time of the principal peak in the chromatogram of the Assay preparation corresponds to that in the chromatogram of the Standard preparation, as obtained in the Assay.
C: The RF value of the principal spot in the chromatogram to pass the test.
Specific rotation: between +84.0 and +87.5 , determined at 20C.
Test solution: 10 mg per mL, in water.
Water: not more than 2.0%.
Residue on ignition: not more than 0.7%.
Heavy metals: 0.001%.
Limit of hydrolysis products: To pass the test.
Limit of methanol: To pass the test.
: not more than 0.1% of methanol is found.
Related compounds: To pass the test.
Sucralose BP Ph Eur Grade Specificatoions:
C12H19Cl3O8 --- 397.6 --- CAS 56038-13-2
Action and use: Sweetening agent.
Content: 98.0 per cent to 102.0 per cent (anhydrous substance).
Appearance: White or almost white, crystalline powder.
Solubility: Freely soluble in water, soluble in anhydrous ethanol, slightly soluble in ethyl acetate.
A. Specific optical rotation (see Tests).
B. Infrared absorption spectrophotometry: Comparisonsucralose CRS.
Specific optical rotation: + 84.0 to + 87.5 (anhydrous substance).
Dissolve 2.50 g in water and dilute to 25.0 mL with the same solvent.
Impurities H and I: To pass the test (0.1 per cent).
Related substances: To pass the test.
impurities A, B, D, E, F, G: any spot, apart from the principal spot, is not more intense than the spot in the chromatogram obtained with reference solution (a) (0.5 per cent).
Water: Maximum 2.0 per cent, determined on 0.500 g.
Sulfated ash: Maximum 0.7 per cent, determined on 1.0 g.
Specified impurities A, B, D, E, F, G, H, I
A. 1,6-dichloro-1,6-dideoxy-β-D-fructofuranosyl 6-O-acetyl-4-chloro-4-deoxy-α-D-galactopyranoside (6-O-acetylsucralose),
B. 1,6-dichloro-1,6-dideoxy-β-D-fructofuranosyl 6-chloro-6-deoxy-α-D-glucopyranoside (1′,6,6′-trichloro-1′,6,6′-trideoxysucrose),
D. 1-chloro-1-deoxy-β-D-fructofuranosyl 4-chloro-4-deoxy-α-D-galactopyranoside (1′,4-dichloro-1′,4-dideoxygalactosucrose),
E. 6-chloro-6-deoxy-β-D-fructofuranosyl 4-chloro-4-deoxy-α-D-galactopyranoside (4,6′-dichloro-4,6′-dideoxygalactosucrose),
F. 1,6-dichloro-1,6-dideoxy-β-D-fructofuranosyl α-D-glucopyranoside (1′,6′-dichloro-1′,6′-dideoxysucrose),
G. 3,6-anhydro-1-chloro-1-deoxy-β-D-fructofuranosyl 4-chloro-4-deoxy-α-D-galactopyranoside (3′,6′-anhydro-1′,4-dichloro-1′,4-dideoxygalactosucrose),
For Original Monographs of IP Indian Pharmacopoeia BP British Pharmacopoeia USP US Pharmacopoeia FCC Food Grade product, please check with the respective web-pages or books.
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Last 27 August, 2022
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Sucralose or Trichlorosucrose SDS, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet 20-Nov-20
Section 1: Chemical Product Identification
Product Name & Other Names: Sucralose or Trichlorosucrose.
EINECS EC Number: 259-952-2
Molecular Weight: 397.64
Chemical Formula: C12H19Cl3O8
Relevant uses and uses advised against (if any): Industrial Manufacturing.
Suppliers: As per letterhead.
Section 2: Hazards Identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008
Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
This substance is not classified as dangerous according to Directive 67/548/EEC.
Labeling according to GHS & Regulation (EC) No 1272/2008
GHS Label Elements
Signal Words: None
Hazards not otherwise classified (HNOC):
May causes mild skin irritation.
May causes mild eye irritation.
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P262: Do not get in eyes, on skin, or on clothing.
P281: Use personal protective equipment as required.
P302+P352 - IF ON SKIN: Wash with plenty of soap and water.
P304 + P340 - IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+313: If eye irritation persists get medical advice/attention.
Section 3: Composition and Information on Ingredients
Product Name & Other Names: Sucralose or Trichlorosucrose.
EINECS EC Number: 259-952-2.
Section 4: First Aid Measures
Always get medical attention after the first aid is over.
Eye Contact: Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Get medical attention if irritation occurs.
Skin Contact: Wash with soap and water. Cover the irritated skin with an emollient. Get medical attention if irritation develops.
Inhalation: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.
Ingestion: Do Not induce vomiting unless directed to do so by medical personnel. If large quantities of this material are swallowed, call a physician immediately. Loosen tight clothing.
Notes to Physician: Provide general supportive measures and treat symptomatically.
Section 5: Fire and Explosion Data
Flammability of the Product: Not classed as fire hazard but it may be combustible at high temperature.
Auto-Ignition Temperature: Not available.
Products of Combustion: Oxides of carbon, hydrogen chloride along with fumes .
Fire Fighting Media and Instructions: Use DRY chemical powder, water spray, carbon dioxide, fog or foam. Do not use water jet. Fire-extinguishing work is done from the windward and the suitable fire-extinguishing method according to the surrounding situation is used. In case of fire in the surroundings: Remove movable containers if safe to do so.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes. Fire-extinguishing work is done from the windward and the suitable fire-extinguishing method according to the surrounding situation is used. Uninvolved persons should evacuate to a safe place.
Section 6: Accidental Release Measures
Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil or water sources.
Methods and materials used for containment Cleanup procedures and Storage:
Small Spill: Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to legal requirements.
Large Spill: Contain spilled material. Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and allow to drain or as required by law. Use personal protective equipment. Keep people away from and upwind of spill/leak. Entry to non-involved personnel should be controlled by roping off, etc.
Section 7: Handling and Storage
Precautions for safe handling: Handling is performed in a well-ventilated place. Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Keep away from sources of ignition. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like oxidizing material, acids.
Section 8: Exposure Controls/Personal Protection
Engineering Controls: Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits.
OSHA PEL: 15 mg/ mg/m3 Total dust; 5 mg/m3 Respirable dust
ACGIH TLV: 10 mg/m3 Inhalable dust; 5 mg/m3 Respirable dust; 15 mg/m3 Total dust.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Dust deposits on floors and other surfaces may pick up moisture and cause the surfaces to become slippery and present safety hazards. Handle in accordance with good industrial hygiene and safety practice.
Section 9: Physical and Chemical Properties
Physical state and appearance: White to off-white powder.
Odor: Practically odorless.
Odor threshold: Not available.
pH: Neutral in aqueous solution.
Relative density: 1.28
Melting Point: Not available.
Initial boiling point and boiling range: 130C with decomposition.
Flash point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility: Soluble in water.
Viscosity: Not available.
Molecular Weight: 397.64
Chemical Formula: C12H19Cl3O8
Section 10: Stability and Reactivity Data
Stability: Stable under normal conditions. When heated at elevated temperatures it may break down with the release of carbon dioxide, carbon monoxide and minor amounts of hydrogen chloride.
Incompatibility with various substances: Oxidizing agents, acids, light and heat.
Hazardous Decomposition Products: May form carbon dioxide and carbon monoxide, hydrogen chloride and various hydrocarbon fume.
Polymerization: Will not occur.
Section 11: Toxicological Information
Toxicity to Animals:
LD50/oral/rat = 10g/kg.
Germ cell mutagenicity: No data available.
Reproductive toxicity: No data available.
Carcinogenicity: The substance is not a known carcinogen as per any authorized agency.
Section 12: Ecological Information
Toxicity to fish: Not available.
BOD5 and COD: Not available.
Toxicity of the Products of Biodegradation: Not available.
Bio accumulative potential: Readily biodegradable.
Mobility in soil: No data available. Expected to be mobile due to water solubility.
Results of PBT and vPvB assessment: Not available.
Section 13: Disposal Considerations
Waste Disposal: To be disposed as per legal requirement.
Section 14: Transport Information
DOT USA, TDG Canada & ADR/RID Europe: Not a DOT controlled material (United States).
IMDG/IMO & IATA: Not regulated.
Section 15: Other Regulatory InformationUSA Federal and State Regulations:
SARA 302: No chemicals in this material are subject to the reporting.
SARA 313: This material does not contain any components that exceed the threshold (De Minimis) reporting levels established by SARA Title III, Section 313.
SARA 311/312 Hazards: No SARA Hazards.
California Prop. 65 Components: This product does not contain any chemicals known to State of California to cause cancer, birth defects, or any other reproductive harm.
Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.