Pyridostigmine Bromide USP BP Ph Eur Grade Manufacturers, with SDS GHS MSDS Sheet |
Supplier, Manufacturer, Exporter of Pyridostigmine Bromide USP BP Ph Eur Grade, Muby Chemicals of Mubychem Group, established in 1976, is the original manufacturers of Specialty Chemicals, Pharmaceutical Excipient, Fragrance Food & Flavor chemicals, Reagent Grade Chemicals, Shale Gas Fracturing Chemicals in India. Mubychem Group has several manufacturing facilities spread across Western India and world wide contacts and toll manufacturers. We are exporting globally to countries like USA, Canada, Europe, UAE, South Africa, Tanzania, Kenya, Egypt, Nigeria, Cameroon, Uganda, Turkey, Mexico, Brazil, Chile, Argentina, Dubai, Korea, Vietnam, Thailand, Malaysia, Indonesia, Australia, China, Germany, France, Italy Portugal, Bangladesh, etc. The products are offered as per required specifications and in correct shape and size in mm or meshs or microns as specified by the buyer. The participating units have one or more accreditations like FDA - cGMP and GLP approval, ISO-9001 Certified, "REACH" Registered, ISO-14001, ISO/IEC 17025, ISO-22000, FSSC 22000, ISO 45001, Kosher Certified, Halal Certified, HACCP, FSSAI. We offer Commercial Pure & IP BP EP Ph Eur USP NF JP FCC Food Grade Analytical Reagent Grades of Chemicals |
| Bookmark this Web Site -- or -- Email This Page Info to a Colleague or Yourself |
Search our website here:
--------- 
Pyridostigmine Bromide CAS Number 101-26-8, EINECS EC Number: 202-929-9, Molecular Formula: C9H13BrN2O2, Molecular Weight: 261.12, HS Code 29333990
How big is your requirement or how small
We serve it all.
Specifications, Safety Data Sheet, Manufacturing process details, Wholesale retail buy sell prices, Uses etc available on line in these pages for Pyridostigmine Bromide.
For SDS MSDS Sheet Click
SDS MSDS Sheet of Pyridostigmine Bromide Manufacturers
Pyridostigmine Bromide
USP BP Ph Eur Grade Suppliers
Pyridostigmine bromide is a cholinergic agent, or anticholinesterase inhibitor, used primarily to treat muscle weakness caused by myasthenia gravis, a neuromuscular disease.
General Properties and Specifications of Pyridostigmine Bromide:
Appearance: White or almost white, crystalline, deliquescent powder.
Assay: 98.5% minimum.
Melting Point: 154C to 157C literature.
Solubility: Freely soluble in water, alcohol. Practically insoluble in ether, acetone, benzene.
Storage: In an airtight container, protected from light. If the substance is sterile, store in a sterile, air-tight, tamper-proof container, protected from light.
Pyridostigmine Bromide USP Grade Specifications:
C9H13BrN2O2 --- 261.12
Pyridinium, 3-[[(dimethylamino)carbonyl]oxy]-1-methyl-, bromide.
3-Hydroxy-1-methylpyridinium bromide dimethylcarbamate
CAS 101-26-8
UNII: KVI301NA53
UNII: 19QM69HH21
Pyridostigmine Bromide contains not less than 98.5 percent and not more than 100.5 percent of C9H13BrN2O2, calculated on the dried basis.
Packaging and storage: Preserve in tight containers.
Identification:
A: Infrared Absorption.
B: Ultraviolet Absorption.
C: To about 100 mg in a test tube add 0.6 mL of 1 N sodium hydroxide: an orange color develops. When the mixture is heated, the color changes to yellow, and a strip of moistened red litmus paper held over the top of the test tube turns blue.
D: A solution (1 in 50) responds to tests for Bromide.
Melting range: between 154C and 157C, the test specimen having been previously dried.
Loss on drying: Dry it in a suitable vacuum drying tube, using phosphorus pentoxide as the desiccant, at 100C for 4 hours: it loses not more than 2.0% of its weight.
Residue on ignition: not more than 0.1%.
Ordinary impurities: To pass the test.
Pyridostigmine Bromide BP Ph Eur Grade Specifications:
C9H13BrN2O2 --- 261.1 CAS 101-26-8
Action and use: Cholinesterase inhibitor.
DEFINITION
3-[(Dimethylcarbamoyl)oxy]-1-methylpyridinium bromide.
Content: 98.5 per cent to 101.0 per cent (dried substance).
CHARACTERS
Appearance: White or almost white, crystalline, deliquescent powder.
Solubility: Very soluble in water and in ethanol (96 per cent).
IDENTIFICATION
A. Infrared absorption spectrophotometry.
B. It gives reaction of bromides.
TESTS
Solution S: Dissolve 1.0 g in carbon dioxide-free water and dilute to 100 mL with the same solvent.
Appearance of solution: Solution S is clear and colourless.
Acidity or alkalinity: To 40 mL of solution S add a few drops of methyl red solution. To 20 mL of this solution add 0.2 mL of0.02 M sodium hydroxide. The solution is yellow. To the other 20 mL add 0.2 mL of 0.02 M hydrochloric acid. The solution is red.
Related substances: To pass the test by Liquid chromatography.
Sulfated ash: Maximum 0.1 per cent, determined on 1.0 g.
Storage: In an airtight container, protected from light. If the substance is sterile, store in a sterile, air-tight, tamper-proof container, protected from light.
For Original Monographs of IP Indian Pharmacopoeia EP Ph Eur European Pharmacopoeia BP British Pharmacopoeia USP US Pharmacopoeia FCC Food Grade product, please check with the respective web-pages or books.
We also manufacture and supply as under:
Pyridoxine Hydrochloride or Vitamin B6
Manufacturers:
MUBY CHEMICALS
Ambernath Mumbai, Ankleshwar Gujarat, India
TEL: (OFFICE) +91-22-65290100, +91-22-65290101
Current Date Time in India GMT+5:30
e-mail: info@mubychem.com
USA, Canada, Mexico and other American neighbouring buyers may
e-mail: us@mubychem.com
Call toll-free 1-877-682-9243 (1-877-MUBYCHEM)
Copyright and Usual Disclaimer is Applicable.
Last 14 May, 2026
Exporters to USA Canada UAE Europe South Africa Tanzania Kenya Uganda Egypt Nigeria Turkey Mexico Brazil Argentina Chile Dubai etc.
Global or International Suppliers, Exporters, Importers, Manufacturers
I shall pass through this world, but once. If therefore, there is any good that I can do, or if there is any favor that I can show to a fellow human being, let me do it now. Let me not defer or neglect it. For I shall not tread this way again
Pyridostigmine Bromide SDS GHS, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet 14-May-26
1. Product Identification
Product Name & Other Names: Pyridostigmine Bromide.
CAS No.: 101-26-8
EINECS EC No.: 202-929-9
Molecular Formula: C9H13BrN2O2
Molecular Weight: 261.12
Relevant uses and uses advised against (if any): Industrial Manufacturing.
Suppliers: As per letterhead.
2. Hazards Identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Hazard Class and Category Code(s), Regulation (EC) No 1272/2008 (CLP):
Acute toxicity, Oral (Category 2), H300
Acute toxicity, Inhalation (Category 2), H330
Acute toxicity, Dermal (Category 1), H310
Skin sensitization, (Category 1), H317
Labeling according to Regulation (EC) No 1272/2008
GHS Label Elements Toxic |
GHS Label Elements Health Hazard |
Signal Words: Danger
Hazard statements:
H300: Fatal if swallowed.
H310: Fatal in contact with skin.
H330: Fatal if inhaled.
H317 May cause an allergic skin reaction.
Precautionary statements:
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P262 Do not get in eyes, on skin, or on clothing.
P264: Wash … thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P330: Rinse mouth.
P304+340+310: IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/doctor.
P305+351+338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do – continue rinsing.
P405: Store locked up.
P501: Dispose of contents/container to authorized agents only.
Classification according to EU Directives 67/548/EEC or 1999/45/EC:
Hazard symbol:
T+ Very toxic
R-phrases:
R26/27/28 Very toxic by inhalation, in contact with skin and if swallowed.
R43 May cause sensitization by skin contact.
3. Composition/Information on Ingredients
Product Name & Other Names: Pyridostigmine Bromide.
CAS No.: 101-26-8
EINECS EC No.: 202-929-9
4. First Aid Measures
Always seek medical attention after first aid measures are provided.
Inhalation: Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.
Ingestion: Never give anything by mouth to an unconscious person. Get medical attention.
Skin Contact: Wipe off excess material from skin then immediately flush skin with plenty of water for at least 15 minutes. Remove contaminated clothing and shoes. Get medical attention. Wash clothing before reusing. Thoroughly clean shoes before reusing them. Get medical attention.
Eye Contact: Immediately flush eyes with plenty of water for at least 15 minutes, lifting lower and upper eyelids occasionally. Get medical attention immediately.
5. Fire Fighting Measures
Products of Combustion: Carbon dioxide, Carbon monoxide, Nitrogen oxide, Bromine, and fumes.
Explosion: May be explosive in presence of heat.
Fire Extinguishing Media: Use dry powder or dry sand should be preferred. Do not use solid water stream. Flammable liquid and vapor. For small (incipient) fires, use, media such as "alcohol" foam, dry chemical, or carbon dioxide. For large fires, apply water from as far as possible. Use large quantities (flooding) of water applied as mist or spray. Vapors are heavier than air and may travel to a source of ignition and flashback. Vapors can spread along the ground and collect in low or confined areas. Never direct a water jet in the container to prevent any splashing of the product which could cause spreading of the fire. Cool containing vessels with water jet to prevent pressure build-up, auto-ignition, or explosion.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes. Fire-extinguishing work is done from the windward and a suitable fire-extinguishing method according to the surrounding situation is used. Uninvolved people should evacuate to a safe place.
6. Accidental Release Measures
Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment cleanup procedures and Storage:
Small Spill: Avoid mist formation. Avoid breathing mist/vapors. Ensure adequate ventilation. Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to local and regional authority requirements.
Large Spill: Remove all sources of ignition. Provide proper ventilation. Keep people away from upwind of spill/leak. Entry to non-involved personnel should be controlled around the leakage area by roping off. Absorb the material on a porous, inert material such as earth, sand, or vermiculite. Carefully sweep up the material without causing dust. Dispose it of in accordance with local regulations.
Large spillages should be contained by use of sand or another inert material. The spillage should be transferred to a suitable container and recovered or disposed of in accordance with local regulations. Because of the danger of spontaneous combustion, any combustible material, such as cloth, used for cleaning spillages, should be saturated with water, and disposed of promptly, preferably by incineration.
7. Handling and Storage
Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. Wash thoroughly after handling it. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces. Wear suitable protective clothing. In case of insufficient ventilation, wear suitable respiratory equipment. Keep away from heat/sparks/open flame/hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original containers. Keep air contact to a minimum. Do not leave the material container open. Store protected from light, heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like oxidizing agents, acids, bases, reducing agents. Store locked up. Storage: In an airtight container, protected from light. If the substance is sterile, store in a sterile, air-tight, tamper-proof container, protected from light.
8. Exposure Controls/Personal Protection
Airborne Exposure Limits: Not Established.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposure as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full-face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.
9. Physical and Chemical Properties
Appearance: White or almost white, crystalline, deliquescent powder.
Odor: Not available.
Odor threshold: Not available.
pH: Not available.
Relative density: Not available.
Boiling Point: Not available.
Melting Point: 154C to 157C literature.
Flash Point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Viscosity: Not available.
Solubility: Freely soluble in water, alcohol. Insoluble in ether, acetone, benzene.
Molecular Formula: C9H13BrN2O2
Molecular Weight: 261.12
10. Stability and Reactivity
Stability: Stable under recommended conditions of use and storage. Vapour/air-mixtures are explosive at high temperature.
Hazardous Decomposition Products: It emits Carbon oxides, Nitrogen oxide, Bromine and Fumes.
Hazardous Polymerization: Will not occur.
Incompatibilities: Strong oxidizing agents, Acids, Bases, Reducing agents.
Conditions to Avoid: Incompatibles, oxidizing agents, heat flame & light.
11. Toxicological Information
Fatal if inhaled, swallowed and in skin contact.
LD50 Oral - Rat – 37500 µg/kg.
Carcinogenicity: Not listed by ACGIH, IARC, NTP, or CA Prop 65.
Epidemiology: No information found.
Teratogenicity: No information found
Reproductive Effects: No information found.
Mutagenicity: No information found.
Neurotoxicity: No information found.
May cause sensitization by skin contact.
12. Ecological Information
Environmental Toxicity: Not available.
Environmental Fate: Not available.
Mobility: Will be mobile in the environment due to its water solubility.
Persistence and Degradability: Soluble in water Persistence is unlikely based on information available.
Toxicity of the Products of Biodegradation: Not available.
13. Disposal Considerations
Whatever cannot be saved for recovery, or recycling should be managed in an appropriate and approved waste disposal facility. Processing use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose of containers and unused contents in accordance with federal, state, and local requirements.
14. Transport Information
DOT USA, TDG Canada & ADR/RID Europe:
Shipping Name: Toxic solid, organic. (Pyridostigmine bromide).
Hazard Class: 6.1, Packing Group: II
UN Number: UN2811
IATA & IMDG/IMO:
Shipping Name: Toxic solid, organic. (Pyridostigmine bromide).
Hazard Class: 6.1(3), Packing Group: II
UN Number: UN2811
15. Regulatory Information
USA:
SARA 311/312 Hazards: Chronic Health Hazard. See section 2.
California prop. 65: Contains no chemical subject to California Prop 65.
16. Other Information
European Labeling in Accordance with EC Directives:
H300: Fatal if swallowed.
H310: Fatal in contact with skin.
H330: Fatal if inhaled.
H317 May cause an allergic skin reaction.
Classification according to EU Directives 67/548/EEC or 1999/45/EC:
Hazard symbols:
T+ Very toxic
R-phrases:
R26/27/28 Very toxic by inhalation, in contact with skin and if swallowed.
R43 May cause sensitization by skin contact.
Disclaimer:
**************************
Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
**************************