Muby Chemicals of Mubychem Group, established in 1976, is the original manufacturers of Specialty Chemicals, Pharmaceutical Excipient, Fragrance & Flavor chemicals, Shale Gas Fracturing Chemicals in India. Mubychem Group has several manufacturing facilities spread across Western India and world wide contacts and toll manufacturers. We are exporting globally to countries like USA, Canada, Europe, UAE, South Africa, Tanzania, Kenya, Egypt, Nigeria, Cameroon, Uganda, Turkey, Mexico, Brazil, Chile, Argentina, Dubai, Korea, Vietnam, Thailand, Malaysia, Indonesia, Australia, China, Germany, France, Italy, Portugal etc. The products are offered as per required specifications and in correct shape and size in mm or meshs or microns as specified by the buyer.
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Purified Talc and Talc Dusting Powder IP BP USP NF FCC Food Grade Manufacturers, SDS GHS MSDS Sheet

Purified Talc: CAS Number: 14807-96-6, EINECS EC Number: 238-877-9, Molecular Formula: 3MgO·4SiO2·H2O, Molecular Weight: 379.27, HS Code ---**

For SDS MSDS Sheet Click
SDS MSDS Sheet of Purified Talc Manufacturers

Purified Talc and Talc Dusting Powder
Purified talc

Talc USP NF Grade

Talc is a powdered, selected, natural, hydrated magnesium silicate. Pure talc has the formula Mg3Si4O10(OH)2. It may contain variable amounts of associated minerals among which chlorites (hydrated aluminum and magnesium silicates), magnesite (magnesium carbonate), calcite (calcium carbonate), and dolomite (calcium and magnesium carbonate) are predominant.

A: The IR spectrum of a potassium bromide dispersion of it exhibits maxima at 3677 ± 2 cm –1, at 1018 ± 2 cm–1, and at 669 ± 2 cm–1.
B: Mix about 200 mg of anhydrous sodium carbonate with 2 g of anhydrous potassium carbonate, and melt in a platinum crucible. To the melt add 100 mg of the substance under test, and continue heating until fusion is complete. Cool, and transfer the fused mixture to a dish or beaker with the aid of about 50 mL of hot water. Add hydrochloric acid to the liquid until effervescence ceases, then add 10 mL more of the acid, and evaporate the mixture on a steam bath to dryness. Cool, add 20 mL of water, boil, and filter the mixture: [NOTE—Save the insoluble residue for use in Identification test C.] To 5 mL of the filtrate add 1 mL of 6 N ammonium hydroxide and 1 mL of ammonium chloride. Filter, if necessary, and add 1 mL of dibasic sodium phosphate to the filtrate: a white crystalline precipitate of magnesium ammonium phosphate is formed.
C: In a lead or platinum crucible and using a copper wire, mix about 100 mg of the insoluble residue as obtained in Identification test B with about 10 mg of sodium fluoride and a few drops of sulfuric acid to give a thin slurry. Cover the crucible with a thin transparent plate of plastic under which a drop of water is suspended, and warm gently. Within a short time, a white ring is rapidly formed around the drop of water.

Microbial limits: If intended for topical administration, the total aerobic microbial count does not exceed 100 cfu per g, and the total combined molds and yeasts count does not exceed 50 cfu per g. If intended for oral administration, the total aerobic microbial count does not exceed 1000 cfu per g, and the total combined molds and yeasts count does not exceed 100 cfu per g.
Acidity and alkalinity: Boil 2.5 g of Talc with 50 mL of carbon dioxide-free water under reflux. Filter under vacuum. To 10 mL of the filtrate, add 0.1 mL of bromothymol blue. Not more than 0.4 mL of 0.01 N hydrochloric acid is required to change the color of the indicator. To 10 mL of the filtrate, add 0.1 mL of phenolphthalein: not more than 0.3 mL of 0.01 N sodium hydroxide is required to change the color of the indicator to pink.
Loss on ignition: Weigh accurately about 1 g, and ignite at 1075 ± 25C to constant weight: it loses not more than 7.0% of its weight.
Water-soluble substances: To 10.0 g add 50 mL of carbon dioxide-free water, heat to boiling, and boil under a reflux condenser for 30 minutes. Allow to cool, filter, and dilute with carbon dioxide-free water to 50.0 mL: the filtrate is neutral to litmus paper. Evaporate 25.0 mL of the filtrate to dryness, and dry at 105C for 1 hour: the weight of the residue does not exceed 5 mg (0.1%).
Limit of iron: To pass the test.
Limit of lead: To pass the test.
Limit of calcium: To pass the test.
Limit of aluminum: : To pass the test.
Absence of asbestos: To pass the test.
Content of magnesium: To pass the test.

Purified Talc BP Grade
Talc, Ph Eur --- 14807-96-6

Powdered, selected, natural, hydrated magnesium silicate. Pure talc has the formula Mg3Si4O10(OH)2 (M r 379.3). It may contain variable amounts of associated minerals among which chlorites (hydrated aluminium and magnesium silicates), magnesite (magnesium carbonate), calcite (calcium carbonate) and dolomite (calcium and magnesium carbonate) are predominant.

Talc derived from deposits that are known to contain associated asbestos is not suitable for pharmaceutical use. The manufacturer is responsible for demonstrating by the test for amphiboles and serpentines that the product is free from asbestos. The presence of amphiboles and of serpentines is revealed by X-ray diffraction or by infrared spectrophotometry (see A and B). If detected, the specific morphological criteria of asbestos are investigated by a suitable method of optical microscopy to determine whether tremolite asbestos or chrysotile is present, as described below.
A. Infrared absorption spectrophotometry.
B. X-ray diffraction.

Appearance: Light, homogeneous, white or almost white powder, greasy to the touch (non abrasive).
Solubility: Practically insoluble in water, in ethanol (96 per cent) and in dilute solutions of acids and alkali hydroxides.

First identificationı A.
Second identificationı B, C.
A. Infrared absorption spectrophotometry.
Absorption bandsı At 3677 ± 2 cm-1, 1018 ± 2 cm-1 and 669 ± 2 cm-1.
B. In a platinum crucible, melt a mixture of 0.2 g of anhydrous sodium carbonate and 2.0 g of potassium carbonate. To the melted mass add 0.1 g of the substance to be examined and heat until the mixture is completely melted. Allow to cool and transfer the melted mass into an evaporating dish with 50 ml of hot water. Add hydrochloric acid until effervescence ceases. Add 10 ml of hydrochloric acid and evaporate to dryness on a water-bath. Allow to cool. Add 20 ml of water, heat to boiling and filter (the residue is used for identification test C). To 5 ml of the filtrate add 1 ml of ammonia and 1 ml of ammonium chloride solution and filter. To the filtrate add 1 ml of disodium hydrogen phosphate solution. A white, crystalline precipitate is formed.
C. The residue obtained in identification test B gives the reaction of silicates.

Solution S1: Weigh 10.0 g into a conical flask fitted with a reflux condenser, add 50 ml of 0.5 M hydrochloric acid gradually while stirring and heat on a water-bath for 30 min. Allow to cool. Transfer the mixture to a beaker and allow the undissolved material to settle. Filter the supernatant through medium-speed filter paper into a 100 ml volumetric flask, retaining as much as possible of the insoluble material in the beaker. Wash the residue and the beaker with 3 quantities, each of 10 ml, of hot water. Wash the filter with 15 ml of hot water, allow the filtrate to cool and dilute to 100.0 ml with the same solvent.
Solution S2: Perchlorates mixed with heavy metals are known to be explosive. Take proper precautions while performing this procedure. Weigh 0.5 g in a 100 ml polytetrafluoroethylene dish, add 5 ml of hydrochloric acid, 5 ml of lead-free nitric acid and 5 ml of perchloric acid. Stir gently then add 35 ml of hydrofluoric acid and evaporate slowly to dryness on a hot plate. To the residue, add 5 ml of hydrochloric acid, cover with a watch-glass, heat to boiling and allow to cool. Rinse the watch-glass and the dish with water. Transfer into a volumetric flask, rinse the dish with water and dilute to 50.0 ml with the same solvent.
Acidity or alkalinity: Boil 2.5 g with 50 ml of carbon dioxide-free water under reflux. Filter in vacuo. To 10 ml of the filtrate add 0.1 ml of bromothymol blue solution; not more than 0.4 ml of 0.01 M hydrochloric acid is required to change the colour of the indicator to green. To 10 ml of the filtrate add 0.1 ml of phenolphthalein solution; not more than 0.3 ml of 0.01 M sodium hydroxide is required to change the colour of the indicator to pink.
Water-soluble substances: Maximum 0.2 per cent.
Aluminium: Maximum 2.0 per cent.
Calcium: Maximum 0.90 per cent.
Iron: Maximum 0.25 per cent.
Lead: Maximum 10.0 ppm.
Magnesium: 17.0 per cent to 19.5 per cent.
Loss on ignition: Maximum 7.0 per cent, determined on 1.00 g by ignition to constant weight at 1050-1100 °C.
Microbial contamination: If intended for topical administration, the total viable aerobic count is not more than a total of 100 bacteria and fungi per gram. If intended for oral administration, the total viable aerobic count is not more than 1000 bacteria and not more than 100 fungi per gram.

The label states, where applicable, that the substance is suitable for oral or topical administration.

Purified Talc IP Grade
We also offer Purified Talc IP grade

Talc Dusting Powder BP Grade

Talc Dusting Powder is a sterile cutaneous powder of suitable fineness consisting of 10% of starch and 90% of Purified Talc.

The starch is triturated with the Purified Talc and passed through a sieve of suitable mesh size (250 μm may be suitable). Either the Purified Talc is sterilised before use or the final product is subjected to a suitable sterilisation procedure.
The dusting powder complies with the requirements stated under Topical Powders and with the following requirement.
Acid-insoluble matter: 86.0 to 91.0% when determined by the following method. Boil 0.5 g with 10 ml of 2M hydrochloric acid for 5 minutes, cool, filter through a tared sintered-glass crucible (ISO 4793, porosity grade 4, is suitable), wash the residue with water until the washings are free from acid and dry to constant weight at 105C.

Talc FCC Food Grade
INS: 553(iii) CAS: [14807-96-6]

Talc occurs as a white to gray-white, unctuous powder. It is a naturally occurring form of hydrous magnesium silicate containing varying proportions of such associated minerals as alpha-quartz, calcite, chlorite, dolomite, kaolin, magnesite and phlogopite. Talc derived from deposits that are known to contain associated asbestos is not food grade. It is insoluble in water and in solutions of alkali hydroxides, but is slightly soluble in dilute mineral acids.
Function: Anticaking agent; coating agent; lubricating and release agent; surface-finishing agent; texturizing agent.

A. The X-ray diffraction pattern of a random powder sample exhibits intense reflections at the following d values: 9.34A, 4.66 A, and 3.12 A .
B. The infrared absorption spectrum of a potassium bromide dispersion of the sample exhibits major peaks at approximately 1015 cm−1 and 450 cm−1.
Acid-Soluble Substances: (as SO4) Not more than 2.5%.
Arsenic: Not more than 3 mg/kg.
Free Alkali: (as NaOH) Not more than 1%.
Lead: Not more than 5 mg/kg.
Loss on Drying: Not more than 0.5%.
Loss on Ignition: Not more than 6.0%.
Soluble Salts: Not more than 0.2%.

For Original Monographs of IP Indian Pharmacopoeia BP British Pharmacopoeia USP US Pharmacopoeia FCC Food Grade product, please check with the respective web-pages or books.


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Last 14 August, 2017

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Purified Talc Powder SDS MSDS Sheet, Material Safety Data Sheet

Section 1: Chemical Product and Company Identification

Product Name: Purified Talc Powder
CAS Number: 14807-96-6
EC number: 238-877-9
Relevant Uses: Industrial and Laboratory use only.
Supplier: As per letterhead.

Section 2: Hazards Identification

GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008

Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
This substance is not classified as dangerous according to Directive 67/548/EEC.

Labeling according to GHS & Regulation (EC) No 1272/2008

GHS Label Elements

Signal Word: None

Precautionary statements:
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P304 + P340 - IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+313: If eye irritation persists get medical advice/attention.

Section 3: Composition and Information on Ingredients

Product Name: Purified Talc Powder
CAS Number: 14807-96-6
EC number: 238-877-9
% by Weight: >95%

Section 4: First Aid Measures

Eye Contact: Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Get medical attention if irritation occurs.
Skin Contact:
Wash with soap and water. Cover the irritated skin with an emollient. Get medical attention if irritation develops.
Inhalation: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.
Ingestion: Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. If large quantities of this material are swallowed, call a physician immediately. Loosen tight clothing such as a collar, tie, belt or waistband.

Section 5: Fire and Explosion Data

Flammability of the Product: Not flammable.
Products of Combustion: Silicon and Magnesium Oxide.
Risks of explosion of the product in presence of mechanical impact: Not available.
Fire Fighting Media and Instructions: Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
SMALL FIRE: Use DRY chemical powder.
LARGE FIRE: Use water spray, fog or foam. Do not use water jet.

Section 6: Accidental Release Measures

Small Spill: Use appropriate tools to put the spilled material in a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to local and regional authority requirements.
Large Spill: Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and allow to evacuate through the sanitary system.

Section 7: Handling and Storage

Precautions: Keep away from sources of ignition. Empty containers pose a fire risk, evaporate the residue under a fume hood. Do not breathe dust.
Keep container tightly closed. Keep container in a cool, well-ventilated area.

Section 8: Exposure Controls/Personal Protection

Engineering Controls: Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to airborne contaminants below the exposure limit.
Personal Protection: Safety glasses. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Gloves.
Personal Protection in Case of a Large Spill: Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be used to avoid inhalation of the product.
Exposure Limits:
TWA: 2 (mg/m3) from ACGIH (TLV) [United States] Respirable.
TWA: 2 (mg/m3) from OSHA (PEL) [United States] Respirable.
TWA: 2 (mg/m3) from NIOSH [United States] Respirable.

Section 9: Physical and Chemical Properties

Physical state and appearance: Grayish Whit Powdered solid.
Odor: Odorless.
Taste: Not available.
Molecular Formula: 3MgO·4SiO2·H2O
Molecular Weight: 379.27
pH (1% soln/water):
Not available.
Melting Point: Not available.
Specific Gravity: 2.5 to 2.8.
Solubility: Insoluble in cold water, hot water.

Section 10: Stability and Reactivity Data

Stability: It is stable.
Instability Temperature: Not available.
Conditions of Instability: Excess heat, incompatible materials.
Incompatibility with various substances: Strong oxidizing agents.
Corrosivity: Not available.
Special Remarks on Reactivity: Not available.
Polymerization: Will not occur.

Section 11: Toxicological Information

Toxicity to Animals:
LD50 Intraperitoneal - Mouse - Not available.
LC50: Not available.
IARC: In 2006, IARC concluded that inhaled talc not containing asbestos or asbestiform fibers is not classifiable as a human carcinogen (Group 3). IARC ruled that there is limited evidence that the use of talcbased body powder for perineal dusting is a possible risk factor for ovarian cancer (Group 2B). This is not a route of exposure relevant to workers and applies only to one specific use of talc.
OSHA: Not listed
ACGIH: A4 – not classified as a human carcinogen

Section 12: Ecological Information

Ecotoxicity: Not available.
Products of Biodegradation: Possibly hazardous short term degradation products are not likely. However, long term degradation products may arise.

Section 13: Disposal Considerations

Waste Disposal: Waste must be disposed of in accordance with environmental control regulations.

Section 14: Transport Information

DOT (US) & ADR/RID: Not dangerous goods
IMDG: Not dangerous goods
IATA: Not dangerous goods

Section 15: Other Regulatory Information

Not available.

16. Other Information

Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.