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Polysorbate 60 Manufacturers, SDS GHS MSDS Sheet
Polysorbate 60: CAS Number: 9005-67-8, EINECS EC Number: 500-020-4, Molecular Formula: C64H126O26, Molecular Weight: 1,311.70, FEMA Number 2916, HS Code ---**
For SDS MSDS Sheet Click
SDS MSDS Sheet of Polysorbate 60 Manufacturers
General Specifications of Polysorbate 60:
Appearance: Semi-solid to Solid Pale Yellow.
Water (by Karl Fischer): Not more than 3.0 %
Residue on ignition (Ash): Not more than 0.25 %
Acid Value: Not more than 2.0 ml
Hydroxyl Value: 81.0 - 96.0
Saponification Value: 45.0 - 55.0
Arsenic (As): Not more than 3 ppm
Cadmium (Cd): Not more than 1 ppm
Mercury (Hg): Not more than 1 ppm
Lead (Pb): Not more than 10 ppm.
Polysorbate 60 BP Grade
Polyoxyethylene 20 Sorbitan Monostearate
Action and use: Non-ionic surfactants.
Mixture of partial esters of fatty acids, mainly Stearic acid 50 (1474), with sorbitol and its anhydrides ethoxylated with approximately 20 moles of ethylene oxide for each mole of sorbitol and sorbitol anhydrides.
Appearance: Yellowish-brown gelatinous mass which becomes a clear liquid at temperatures above 25C.
Solubility: Soluble in water, in ethanol, in ethyl acetate and in methanol, practically insoluble in fatty oils and in liquid paraffin.
Relative density: About 1.10.
Viscosity: about 400 mPa·s at 30C.
First identication A, D.
Second identification B, C, D, E.
A. Infrared absorption spectrophotometry.
B. It complies with the test for hydroxyl value.
C. It complies with the test for saponification value.
D. It complies with the test for composition of fatty acids.
E. Dissolve 0.1 g in 5 ml of methylene chloride. Add 0.1 g of potassium thiocyanate and 0.1 g of cobalt nitrate. Stir with a glass rod. The solution becomes blue.
Acid value: Maximum 2.0.
Hydroxyl value: 81 to 96.
Peroxide value: Maximum 10.0.
Saponification value: 45 to 55, determined on 4.0 g.
Composition of fatty acids:
Composition of the fatty acid fraction of the substance:
stearic acid : 40.0 per cent to 60.0 per cent;
sum of the contents of palmitic and stearic acids: minimum 90.0 per cent.
Ethylene oxide and dioxan: Maximum 1 ppm of ethylene oxide and maximum 10 ppm of dioxan.
Heavy metals: Maximum 10 ppm.
Water: Maximum 3.0 per cent, determined on 1.00 g.
Total ash: Maximum 0.25 per cent, determined on 2.0 g.
Polysorbate 60 USP NF Grade
Sorbitan, monooctadecanoate, poly(oxy-1,2-ethanediyl) derivs.
Polyoxyethylene 20 sorbitan monostearate [Compound usually contains also associated fatty acids.]
Polysorbate 60 is a mixture of stearate and palmitate esters of sorbitol and its anhydrides copolymerized with approximately 20 moles of ethylene oxide for each mole of sorbitol and sorbitol anhydrides.
A: It meets the requirements for Identification tests A and C under Polysorbate 80.
B: To 2 mL of a solution (1 in 20) add 0.5 mL of bromine, dropwise: the bromine is not decolorized (distinction from Polysorbate 80).
Hydroxyl value: between 81 and 96.
Saponification value: between 45 and 55.
Organic volatile impurities: meets the requirements. [NOTE—A G16 column has been shown to be an appropriate secondary column.] (Official until July 1, 2007)
Other requirements: It meets the requirements for Water, Residue on ignition, Heavy metals, and Acid value under Polysorbate 80.
Polysorbate 60 FCC Food Grade
Polyoxyethylene (20) Sorbitan Monostearate; Sorbitan
Monooctadecanoate; Poly(oxy-1,2-ethanediyl) Derivative
INS: 435 CAS: [9005-67-8]
Polysorbate 60 occurs as a yellow to orange colored, oily liquid or semigel. It is a mixture of stearate and palmitate partial esters of sorbitol and sorbitol anhydrides condensed with approximately 20 moles of ethylene oxide (C2H4O) for each mole of sorbitol and its mono- and dianhydrides. It is soluble in water, in aniline, in ethyl acetate, and in toluene, but it is insoluble in mineral oil and in vegetable oils.
Function: Emulsifier; stabilizer.
A. Add 5 mL of 1 N sodium hydroxide to 5 mL of a 1:20 aqueous solution, boil for a few minutes, cool, and acidify with 2.7 N hydrochloric acid. The solution is strongly opalescent.
B. A 60:40 (v/v) mixture of Polysorbate 60:water at 25C or cooler yields a gelatinous mass.
Assay for Oxyethylene Content: Not less than 65.0% and not more than 69.5% of oxyethylene groups (—C2H4O—), equivalent to between 97.0% and 103.0% of Polysorbate 60, calculated on the anhydrous basis.
Acid Value: Not more than 2.
1,4-Dioxane: Not more than 10 mg/kg.
Hydroxyl Value: Between 81 and 96.
Lead: Not more than 2 mg/kg.
Residue on Ignition: Not more than 0.25%.
Saponification Value: Between 45 and 55.
Stearic and Palmitic Acids: Between 21.5 and 26.0 g per 100 g of sample.
Water: Not more than 3.0%.
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Last 19 December, 2017
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Polysorbate 60 SDS MSDS Sheet, Material Safety Data Sheet
1. PRODUCT DESCRIPTION
Product Name: Polysorbate 60
CAS Number: 9005-67-8
EINECS EC Number: 500-020-4
Molecular Weight: 1,311.70
Molecular Formula: C64H126O26
Recommended usage: Industrial Manufacturing.
Suppliers: As per letterhead.
2. HAZARD IDENTIFICATION
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008
Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
This substance is not classified as dangerous according to Directive 67/548/EEC.
Labeling according to GHS & Regulation (EC) No 1272/2008
GHS Label Elements
Signal Words: None
Hazards not otherwise classified (HNOC):
May causes mild skin irritation.
May causes mild eye irritation.
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P262: Do not get in eyes, on skin, or on clothing.
P281: Use personal protective equipment as required.
P302+P352 - IF ON SKIN: Wash with plenty of soap and water.
P303+P361+P353 - IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
P304 + P340 - IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+313: If eye irritation persists get medical advice/attention.
3. COMPOSITION/INFORMATION ON INGREDIENTS
Product Name: Polysorbate 60
CAS Number: 9005-67-8
EINECS EC Number: 500-020-4
4. FIRST AID MEASURES
Always get medical attention after the first aid is over.
Emergency and First Aid Procedures:
Eyes - Flush with water for at least 15 minutes, raising and lowering eyelids occasionally. Get medical attention if irritation persists.
Skin - Thoroughly wash exposed area for at least 15 minutes. Remove contaminated clothing. Launder contaminated clothing before reuse. Get medical attention if irritation persists.
Ingestion - If Polysorbate 60 is swallowed, if conscious, give plenty of water. Immediately call a physician. Never give anything by mouth to an unconscious person.
Inhalation - Remove to fresh air. Give oxygen if breathing is difficult; give artificial respiration if breathing has stopped. Get medical attention.
5. FIREFIGHTING PROCEDURES
Extinguisher Media: Water spray. Carbon dioxide (CO 2). Dry chemical. alcohol-resistant foam.
Flammable Limits in Air % by Volume: N/A
Special Fire fighting Procedures: Firefighters should wear full protective equipment and NIOSH approved self-contained breathing apparatus.
6. SPILL OR LEAK PROCEDURES
Ventilate area of leak or spill. Wear appropriate personal protective equipment.
Sweep up and containerize for reclamation or disposal. Vacuuming or wet sweeping may be used to avoid dust dispersal. Do not let product enter drains. Small amounts of residue may be flushed to sewer with plenty of water.
7. SPECIAL PRECAUTIONS
Keep in a well closed container stored under cold to warm conditions in a ventilated area. Protect against physical damage. Containers of this material may be hazardous when empty since they retain product residues (dust, solids); observe all warnings and precautions listed for the product.
8. SPECIAL PROTECTION INFORMATION
Exposure Guidelines: This product does not contain any hazardous materials with occupational exposure limits established by the region specific regulatory bodies. Better keep it under 10 mg/m3
Respiratory Protection (Specify Type): None needed under normal conditions of use with adequate ventilation. NIOSH approved equipment should be worn if PELs are exceeded.
Ventilation Local Exhaust: Yes
Eye Protection: Splash proof chemical safety goggles should be worn at all times.
Other Protective Clothing or Equipment: Lab apron, eye wash, and safety shower.
9. PHYSICAL DATA
Molecular Weight: 1,311.70
Molecular Formula: C64H126O26
Appearance and Odor: Viscous yellow liquid material. Odorless.
Melting Point: NA.
Boiling Point: NA.
Density: 1.044 g/cm3
10. REACTIVITY DATA
Stability: Polysorbate 60 is stable
Conditions to Avoid: Heat and Strong oxidizing agents.
Incompatibility (Materials to Avoid): Strong oxidizing and bases.
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide
Hazardous Polymerization: Will not occur
11. TOXICITY DATA
LD50 Oral - Rat - > 62,640 mg/kg
LD50 Intravenous - Rat - 1,220 mg/kg
Carcinogenicity: No product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC, NTP, ACGIH & OSHA.
12. ECOLOGICAL DATA
Toxicity to fish: LC50 - Oryzias latipes - 240 mg/l - 48 h
Toxicity: Avoid release into the environment.
Persistence and degradability: No data available
Mobility in soil: No data available
13. DISPOSAL INFORMATION
Waste Disposal Methods: Dispose Polysorbate 60 in accordance with all applicable Federal, State and Local regulations.
14. TRANSPORT INFORMATION
DOT & ADR/RID: Not regulated.
IMDG: Not regulated.
IATA: Not regulated.
15. REGULATORY INFORMATION
SARA 302 Components: SARA 302: No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302.
SARA 313 Components: This material does not contain any chemical components with known CAS numbers that exceed the threshold (De Minimis) reporting levels established by SARA Title III, Section 313.
SARA 311/312 Hazards: No SARA Hazards
California Prop. 65 Components: This product does not contain any chemicals known to State of California to cause cancer, birth defects, or any other reproductive harm.
16. ADDITIONAL INFORMATIONDisclaimer:
Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.