Tween - Polysorbate 20 BP USP NF FCC Food Grade Manufacturers, with SDS GHS MSDS Sheet
Supplier, Manufacturer, Exporter of Tween - Polysorbate 20, Muby Chemicals of Mubychem Group, established in 1976, is the original manufacturers of Specialty Chemicals, Pharmaceutical Excipient, Fragrance Food & Flavor chemicals, Reagent Grade Chemicals, Shale Gas Fracturing Chemicals in India. Mubychem Group has several manufacturing facilities spread across Western India and world wide contacts and toll manufacturers. We are exporting globally to countries like USA, Canada, Europe, UAE, South Africa, Tanzania, Kenya, Egypt, Nigeria, Cameroon, Uganda, Turkey, Mexico, Brazil, Chile, Argentina, Dubai, Korea, Vietnam, Thailand, Malaysia, Indonesia, Australia, China, Germany, France, Italy, Portugal etc.
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Tween - Polysorbate 20: CAS Number: 9005-64-5, EINECS EC Number: 500-018-3, Molecular Formula: C58H114O26, Molecular Weight: 1227.54, FEMA Number 2915, HS Code ---**
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SDS MSDS Sheet of Polysorbate 20 Manufacturers
Spanish Polisorbato 80, 60, 40
Tween - BP USP NF FCC Food Grade Suppliers
General Specifications of Polysorbate 20
Appearance: Faint Yellow to Yellow Viscous Liquid
Refractive index at 20C: 1.467 - 1.473
Water (by Karl Fischer): Not more than <_ 3.0 %
Residue on ignition (Ash): Not more than 0.25 %
Acid Value: ): Not more than 2.0 ml
Heavy Metal: ): Not more than 10 ppm
Hydroxyl Value: ): Not more than 96.0 - 108.0
Saponification Value: 40.0 - 50.0
Arsenic (As): 3 ppm
Cadmium (Cd): 1 ppm
Mercury (Hg): 1 ppm
Lead (Pb): 2 ppm.
Polysorbate 20 BP Grade
Polyoxyethylene 20 Sorbitan Monolaurate
Action and use: Non-ionic surfactants.
Mixture of partial esters of fatty acids, mainly lauric (dodecanoic) acid, with sorbitol and its anhydrides ethoxylated with approximately 20 moles of ethylene oxide for each mole of sorbitol and sorbitol anhydrides.
Appearance: Oily, yellow to brownish-yellow, clear or slightly opalescent liquid.
Solubility: Soluble in water, in ethanol, in ethyl acetate and in methanol, practically insoluble in fatty oils and in liquid paraffin.
Relative density: About 1.10.
Viscosity: About 400 mPa·s at 25 °C.
First identicationıA, D.
Second identificationıB, C, D, E.
A. Infrared absorption spectrophotometry.
B. It complies with the test for hydroxyl value.
C. It complies with the test for saponification value.
D. It complies with the test for composition of fatty acids.
E. Dissolve 0.1 g in 5 ml of methylene chloride. Add 0.1 g of potassium thiocyanate and 0.1 g of cobalt nitrate. Stir with a glass rod. The solution becomes blue.
Acid value: Maximum 2.0.
Hydroxyl value: 96 to 108.
Peroxide value: Maximum 10.0.
Saponification value: 40 to 50, determined on 4.0 g.
Composition of fatty acids:
Composition of the fatty acid fraction of the substance:
caproic acid : maximum 1.0 per cent;
caprylic acid : maximum 10.0 per cent;
capric acid: maximum 10.0 per cent;
lauric acid : 40.0 per cent to 60.0 per cent;
myristic acid : 14.0 per cent to 25.0 per cent;
palmitic acid : 7.0 per cent to 15.0 per cent;
stearic acid : maximum 7.0 per cent;
oleic acid : maximum 11.0 per cent;
linoleic acid : maximum 3.0 per cent.
Ethylene oxide and dioxan: Maximum 1 ppm of ethylene oxide and 10 ppm of dioxan.
Heavy metals: Maximum 10 ppm.
Water: Maximum 3.0 per cent, determined on 1.00 g.
Total ash: Maximum 0.25 per cent, determined on 2.0 g.
Polysorbate 20 USP NF Grade
Sorbitan, monododecanoate, poly(oxy-1,2-ethanediyl) derivs.
Polyoxyethylene 20 sorbitan monolaurate [CAS 9005-64-5].
Polysorbate 20 is a laurate ester of sorbitol and its anhydrides copolymerized with approximately 20 moles of ethylene oxide for each mole of sorbitol and sorbitol anhydrides.
A: It meets the requirements of Identification test A under Polysorbate 80.
B: To 2 mL of a solution (1 in 20) add 0.5 mL of bromine dropwise: the bromine is not decolorized (distinction from Polysorbate 80).
Hydroxyl value: between 96 and 108.
Saponification value: between 40 and 50.
Organic volatile impurities: meets the requirements. (Official until July 1, 2007)
Other requirements: It meets the requirements for Water, Residue on ignition, Heavy metals, and Acid value under Polysorbate 80.
Polysorbate 20 FCC Food Grade
Polyoxyethylene (20) Sorbitan Monolaurate; Sorbitan
Monododecanoate; Poly(oxy-1,2-ethanediyl) Derivative
INS: 432 CAS: [CAS 9005-64-5]
Polysorbate 20 occurs as a yellow- to amber-colored liquid. It is a mixture of laurate partial esters of sorbitol and sorbitol anhydrides condensed with approximately 20 moles of ethylene oxide (C2H4O) for each mole of sorbitol and its monoand dianhydrides. It is soluble in water, in alcohol, in ethyl acetate, in methanol, and in dioxane, but it is insoluble in mineral oil and in mineral spirits.
Function: Emulsifier; stabilizer.
Identification: Add 5 mL of 1 N sodium hydroxide to 5 mL of a 1:20 aqueous solution, boil for a few minutes, cool, and acidify with 2.7 N hydrochloric acid. The solution is strongly opalescent.
Assay for Oxyethylene Content: Not less than 70.0% and not more than 74.0% of oxyethylene groups (—C2H4O—), equivalent to between 97.3% and 103.0% of Polysorbate 20 calculated on the anhydrous basis.
Acid Value: Not more than 2.
1,4-Dioxane: Not more than 10 mg/kg.
Hydroxyl Value: Between 96 and 108.
Lauric Acid: Between 15 and 17 g per 100 g of sample.
Lead: Not more than 2 mg/kg.
Residue on Ignition: Not more than 0.25%.
Saponification Value: Between 40 and 50.
Water: Not more than 3.0%.
We manufacture and supply as under:
Poly Sorbate 80
Ambernath Mumbai, Ankleshwar Gujarat, India
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Last 27 August, 2022
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Polysorbate 20 SDS, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet 13-Nov-20
1. PRODUCT DESCRIPTION
Product Name & Other Names: Polysorbate 20.
CAS Number: 9005-64-5
EINECS EC Number: 500-018-3
Molecular Weight: 1227.54
Molecular Formula: C58H114O26
Relevant uses and uses advised against (if any): Industrial Manufacturing.
Suppliers: As per letterhead.
2. HAZARD IDENTIFICATION
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008
Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
This substance is not classified as dangerous according to Directive 67/548/EEC.
Labeling according to GHS & Regulation (EC) No 1272/2008
GHS Label Elements
Signal Words: None
Hazards not otherwise classified (HNOC):
May causes mild skin irritation.
May causes mild eye irritation.
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P262: Do not get in eyes, on skin, or on clothing.
P281: Use personal protective equipment as required.
P302+P352 - IF ON SKIN: Wash with plenty of soap and water.
P304 + P340 - IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+313: If eye irritation persists get medical advice/attention.
3. COMPOSITION/INFORMATION ON INGREDIENTS
Product Name & Other Names: Polysorbate 20.
CAS Number: 9005-64-5
EINECS EC Number: 500-018-3
4. FIRST AID MEASURES
Always get medical attention after the first aid is over.
Emergency and First Aid Procedures:
Eyes - Flush with water for at least 15 minutes, raising and lowering eyelids occasionally. Get medical attention if irritation persists.
Skin - Thoroughly wash exposed area for at least 15 minutes. Remove contaminated clothing. Launder contaminated clothing before reuse. Get medical attention if irritation persists.
Ingestion - If Polysorbate 20 is swallowed, if conscious, give plenty of water. Immediately call a physician. Never give anything by mouth to an unconscious person.
Inhalation - Remove to fresh air. Give oxygen if breathing is difficult; give artificial respiration if breathing has stopped. Get medical attention.
5. FIREFIGHTING PROCEDURES
Extinguisher Media: Water spray. Carbon dioxide (CO 2). Dry chemical. alcohol-resistant foam.
Flammable Limits in Air % by Volume: N/A
Special Fire fighting Procedures: Firefighters should wear full protective equipment and NIOSH approved self-contained breathing apparatus.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes. Fire-extinguishing work is done from the windward and the suitable fire-extinguishing method according to the surrounding situation is used. Uninvolved persons should evacuate to a safe place.
6. SPILL OR LEAK PROCEDURES
Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment Cleanup procedures and Storage: Do not inhale dust, vapors, mist, or gas. Avoid dust formation. Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g. sand, earth, diatomaceous earth, vermiculite). Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and allow to evacuate as per law.
7. SPECIAL PRECAUTIONS
Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. In case of insufficient ventilation, wear suitable respiratory equipment. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like strong oxidizing agents and bases.
8. SPECIAL PROTECTION INFORMATION
Exposure Guidelines: This product does not contain any hazardous materials with occupational exposure limits established by the region-specific regulatory bodies.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Dust deposits on floors and other surfaces may pick up moisture and cause the surfaces to become slippery and present safety hazards. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.
9. PHYSICAL DATA
Appearance and Odor: Yellow liquid material.
Odor threshold: Not available.
pH: about 7
Relative density: 1.105 literature.
Melting point/freezing point: Not available.
Initial boiling point and boiling range: Not available.
Flash point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility(ies): Soluble in water.
Viscosity: Not available.
Molecular Weight: 1227.54
Molecular Formula: C58H114O26
10. REACTIVITY DATA
Stability: Stable under normal storage conditions.
Conditions to Avoid: Heat.
Incompatibility (Materials to Avoid): Strong oxidizing and bases.
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide
Hazardous Polymerization: Will not occur.
11. TOXICITY DATA
LD50 Oral - Rat - 40,554 mg/kg
Carcinogenicity: No product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC, NTP, ACGIH & OSHA.
Mutagenic Effects: Not available.
Developmental Toxicity: Not available.
Reproductive Effects: No information available.
12. ECOLOGICAL DATA
Toxicity: Avoid release into the environment.
Toxicity to fish: LC50 - other fish - 350 mg/l - 24 h
Persistence and Degradability: No information available.
Mobility: No information available.
Bioaccumulation/ Accumulation: No information available.
Results of PBT and vPvB assessment: No data available for assessment.
13. DISPOSAL INFORMATION
Waste Disposal Methods: Dispose Polysorbate 20 in accordance with all applicable Federal, State and Local regulations.
14. TRANSPORT INFORMATION
DOT USA, TDG Canada & ADR/RID Europe: Not regulated.
IMDG/IMO: Not regulated.
IATA: Not regulated.
15. REGULATORY INFORMATION
USA:16. ADDITIONAL INFORMATION
SARA 302 Components: SARA 302: No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302.
SARA 313 Components: This material does not contain any chemical components with known CAS numbers that exceed the threshold (De Minimis) reporting levels established by SARA Title III, Section 313.
SARA 311/312 Hazards: No SARA Hazards
California Prop. 65 Components: This product does not contain any chemicals known to State of California to cause cancer, birth defects, or any other reproductive harm.
Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.