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Dimeticone BP Dimethicone USP NF Grade Manufacturers, SDS GHS MSDS Sheet
Dimeticone or Dimethicone: CAS Number: 9006-75-9 or 9016-00-6 or 63148-62-9, EINECS EC Number: yyyyy, Molecular Formula: yyyyy, Molecular Weight: yyyyy, HS Code ---**
For SDS MSDS Sheet Click
SDS MSDS Sheet of Dimeticone or Dimethicone Manufacturers
Dimeticone BP Dimethicone USP NF
Dimeticone BP Grade
Ph Eur --- 9006-75-9
Action and use: Antifoaming agent; water repellent. When dimethicone is demanded, Dimeticone shall be supplied.
Poly(dimethylsiloxane) obtained by hydrolysis and polycondensation of dichlorodimethylsilane and chlorotrimethylsilane. Different grades of dimeticone exist which are distinguished by a number indicating the nominal kinematic viscosity placed after the name.
Their degree of polymerisation (n = 20 to 400) is such that their kinematic viscosities are nominally between 20 mm2·s-1 and 1300 mm2·s-1.
Dimeticones with a nominal viscosity of 50 mm2·s-1 or lower are intended for external use only.
Appearance: Clear, colourless liquid of various viscosities.
Solubility: Practically insoluble in water, very slightly soluble or practically insoluble in anhydrous ethanol, miscible with ethyl acetate, with methyl ethyl ketone and with toluene.
A. It is identified by its kinematic viscosity at 25C (see Tests).
B. Infrared absorption spectrophotometry.
C. Heat 0.5 g in a test-tube over a small flame until white fumes begin to appear. Invert the tube over a 2nd tube containing 1 ml of a 1 g/l solution of chromotropic acid sodium salt in sulphuric acid so that the fumes reach the solution. Shake the 2nd tube for about 10 s and heat on a water-bath for 5 min. The solution is violet.
D. In a platinum crucible, prepare the sulphated ash using 50 mg. The residue is a white powder that gives the reaction of silicates.
Acidity: To 2.0 g add 25 ml of a mixture of equal volumes of anhydrous ethanol and ether, previously neutralised to 0.2 ml of bromothymol blue solution and shake. Not more than 0.15 ml of 0.01 M sodium hydroxide is required to change the colour of the solution to blue.
Viscosity: 90 per cent to 110 per cent of the nominal kinematic viscosity stated on the label, determined at 25C.
Mineral oils: Place 2 g in a test-tube and examine in ultraviolet light at 365 nm. The fluorescence is not more intense than that of a solution containing 0.1 ppm of quinine sulphate in 0.005 M sulphuric acid examined in the same conditions.
Phenylated compounds: Dissolve 5.0 g with shaking in 10 ml of cyclohexane. At wavelengths from 250 nm to 270 nm, the absorbance of the solution is not greater than 0.2.
Heavy metals: Maximum 5 ppm.
Volatile matter: Maximum 0.3 per cent, for dimeticones with a nominal viscosity greater than 50 mm2·s-1, determined on 1.00 g by heating in an oven at 150 °C for 2 h. Carry out the test using a dish 60 mm in diameter and 10 mm deep.
Dimethicone USP Grade
-(Trimethylsilyl)- -methylpoly[oxy(dimethylsilylene)] [9006-65-9].
Dimethicone is a mixture of fully methylated linear siloxane polymers containing repeating units of the formula: [–(CH3)2SiO–]n stabilized with trimethylsiloxy end-blocking units of the formula: [(CH3)3SiO–] wherein n has an average value such that the corresponding nominal viscosity is in a discrete range between 20 and 30,000 centistokes. It contains not less than 97.0 percent and not more than 103.0 percent of polydimethylsiloxane ([–(CH3)2SiO–]n). The requirements for viscosity, specific gravity, refractive index, and loss on heating differ for the several types of Dimethicone, as set forth in the accompanying table.
Labeling: Label it to indicate its nominal viscosity value. Dimethicone intended for use in coating containers that come in contact with articles for parenteral use is so labeled.
Identification: Its IR absorption spectrum, obtained as directed in the Assay, exhibits maxima only at the same wavelengths as that of USP Polydimethylsiloxane RS, obtained as directed in the Assay.
Specific gravity: within the limits specified in the accompanying table.
Viscosity: Determine the viscosity of Dimethicone having a nominal viscosity of less than 1000 centistokes at 25 ± 0.1 , using a capillary viscosimeter. Determine the viscosity of Dimethicone having a nominal viscosity of 1000 centistokes or greater at 25 ± 0.1 , using a rotational viscosimeter. The viscosity is within the limits specified in the accompanying table.
Refractive index: within the limits specified in the accompanying table.
Acidity: Dissolve 15.0 g in a mixture of 15 mL of toluene and 15 mL of butyl alcohol, previously neutralized to bromophenol blue and titrate with 0.050 N alcoholic potassium hydroxide to a bromophenol blue endpoint: not more than 0.10 mL is required.
Loss on heating: Preheat an open aluminum vessel (60 mm in diameter and 10 mm high) at 150C for 30 minutes, and allow to cool to room temperature. Tare the vessel, transfer to it about 1 g of Dimethicone, accurately weighed, heat at 150C in a circulating air oven for 2 hours, and allow to come to room temperature in a desiccator before weighing: it loses not more than the maximum percentage of its weight specified in the accompanying table.
Heavy metals: To pass the test (5 microgm per g).
Bacterial endotoxins: To pass the test: equivalent to not more than 10 Endotoxin Units per mL of the Dimethicone taken.
Nominal Viscosity &
Loss on heating
Min. to Max.
Min. to Max.
Min. to Max.
020 ------ Max. 20.0
18 to 22
0.946 to 0.954
050 ------ Max. 2.0
47.5 to 52.5
0.955 to 0.965
100 ------ Max. 0.3
95 to 105
0.962 to 0.970
200 ------ Max. 0.3
190 to 220
0.964 to 0.972
350 ------ Max. 0.3
332.5 to 367.5
0.965 to 0.973
500 ------ Max. 0.3
475 to 525
0.967 to 0.975
1.4013 to 1.4053
1000 ------ Max. 0.3
950 to 1050
0.967 to 0.975
1.4013 to 1.4053
12,500 ------ Max. 2.0
11,875 to 13,125
1.4015 to 1.4055
30,000 ------ Max. 2.0
27,000 to 33,000
0.969 to 0.977
1.4010 to 1.4100
For Original Monographs of IP Indian Pharmacopoeia BP British Pharmacopoeia USP US Pharmacopoeia FCC Food Grade product, please check with the respective web-pages or books.
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Last : 22 March, 2017
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Dimeticone SDS GHS MSDS Sheet, Material Safety Data Sheet
Section 1: Chemical Product and Company Identification
Product Name: Dimeticone.
Synonym: Dimethicone, Poly(dimethylsiloxane)
CAS Number: 9006-75-9 or 9016-00-6 or 63148-62-9
EINECS EC Code: -
Recommended usage: Industrial Manufacturing.
Suppliers: As per letterhead.
Section 2: Hazards Identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Hazard Class and Category Code(s), Regulation (EC) No 1272/2008 (CLP)
Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
This substance is not classified as dangerous according to Directive 67/548/EEC.
Labeling Regulation as per GHS & EC 1272/2008 (CLP) & GHS
GHS Label Elements
Signal Word: None
Hazards not otherwise classified (HNOC):
May causes mild skin irritation.
May causes mild eye irritation.
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P262: Do not get in eyes, on skin, or on clothing.
P281: Use personal protective equipment as required.
P302+P352 - IF ON SKIN: Wash with plenty of soap and water.
P303+P361+P353 - IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
P304 + P340 - IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+313: If eye irritation persists get medical advice/attention.
Section 3: Composition and Information on Ingredients
Product Name: Dimeticone.
Synonym: Dimethicone, Poly(dimethylsiloxane)
CAS Number: 9006-75-9
EINECS EC Code: -
Section 4: First Aid Measures
Always seek medical advice after the first aid treatment.
Skin: Rinse with water. Soap may be used. Seek Medical Aid.
Eyes: Wash eyes with plenty of water for at least 15 minutes, lifting lids occasionally. Seek Medical Aid.
Inhalation: Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Ingestion: If swallowed, induce vomiting immediately after giving two glasses of water. Never give anything by mouth to an unconscious person.
Section 5: Fire and Explosion Data
Flammability of the Product: It is flammable on heating.
Products of Combustion: Oxides of Carbon, Silicone and fumes.
Fire Fighting Media and Instructions: Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. Wear self-contained breathing apparatus for firefighting if necessary.
Section 6: Accidental Release Measures
Small Spill: Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to legal requirements.
Large Spill: Do not inhale vapors, mist, or gas. Avoid dust formation. Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and allow to evacuate through the sanitary system. Be careful that the product is not present at a concentration level above TLV. Check TLV with local authorities.
Section 7: Handling and Storage
Precautions: Do not breathe dust. Keep away from incompatibles such as oxidizing agents, acids.
Storage: Keep container tightly closed. Keep container in a cool, well-ventilated area.
Section 8: Exposure Controls/Personal Protection
Engineering Controls: Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to airborne contaminants below the exposure limit.
Personal Protection: Safety glasses. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent Gloves.
Personal Protection in Case of a Large Spill: Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be used to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling this product.
Section 9: Physical and Chemical Properties
Physical state and appearance: Clear liquid.
Specific Gravity: 0.94 to 0.97
pH (5% soln/water): NA.
Solubility: Soluble in water.
Section 10: Stability and Reactivity Data
Stability: It is stable in room temperature in closed containers under normal storage & handling.
Conditions of instability: Incompatible materials, Heat.
Incompatibility with various substances: Avoid high temperatures, sparks, open flames and moisture. Avoid contact with strong oxidizing agents acids and bases.
Polymerization: Will not occur.
Section 11: Toxicological Information
LD50 Oral - Rat - >1000 mg/kg
Carcinogenic Effects: Not a reported carcinogen by IARC, NTP, ACGIH, OSHA.
Section 12: Ecological Information
Toxicity to fish: LC50 - Oncorhynchus mykiss (rainbow trout) - > 10,000 mg/l - 96 h.
BOD5 and COD: Not available.
Products of Biodegradation: The product itself and its products of degradation are not toxic.
Section 13: Disposal Considerations
Waste Disposal: Waste must be disposed of in accordance with federal, state and local environmental control regulations.
Section 14: Transport Information
DOT (US): Not dangerous goods
IMDG: Not dangerous goods
IATA: Not dangerous goods
ADR/RID: Not dangerous goods
Section 15: Other Regulatory Information
OSHA: None of the chemicals in this product are considered highly hazardous by OSHA.
California Prop 65: California No Significant Risk Level: None of the chemicals in this product are listed.
WHMIS Hazard Class: not controlled.
EINECS EC Code: --Disclaimer:
Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.