1,2-Dioleoyloxy-3-trimethylammoniumpropane chloride or Cationics DOTAP Chloride or N-[1-(2,3-Dioleoyloxy)propyl]-N,N,N-trimethylammonium chloride Manufacturers, with SDS GHS MSDS Sheet

Supplier, Manufacturer, Exporter of 1,2-Dioleoyloxy-3-trimethylammoniumpropane chloride, Muby Chemicals of Mubychem Group, established in 1976, is the original manufacturers of Specialty Chemicals, Pharmaceutical Excipient, Fragrance Food & Flavor chemicals, Reagent Grade Chemicals, Shale Gas Fracturing Chemicals in India. Mubychem Group has several manufacturing facilities spread across Western India and world wide contacts and toll manufacturers. We are exporting globally to countries like USA, Canada, Europe, UAE, South Africa, Tanzania, Kenya, Egypt, Nigeria, Cameroon, Uganda, Turkey, Mexico, Brazil, Chile, Argentina, Dubai, Korea, Vietnam, Thailand, Malaysia, Indonesia, Australia, China, Germany, France, Italy, Portugal etc.

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1,2-Dioleoyloxy-3-trimethylammoniumpropane chloride or Cationics DOTAP Chloride or N-[1-(2,3-Dioleoyloxy)propyl]-N,N,N-trimethylammonium chloride: CAS Number: 132172-61-3 alternate 113669-21-9, EINECS EC Number: NA, Molecular Formula: C42H80ClNO4, Molecular Weight: 698.54, HS Code ---**

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SDS MSDS Sheet of 1,2-dioleoyloxy-3-trimethylammoniumpropane chloride or Cationics DOTAP Chloride or N-[1-(2,3-Dioleoyloxy)propyl]-N,N,N-trimethylammonium chloride Manufacturers

1,2-Dioleoyloxy-3-trimethylammoniumpropane chloride or Cationics DOTAP Chloride
N-[1-(2,3-Dioleoyloxy)propyl]-N,N,N-trimethylammonium chloride Pure Suppliers
1,2-dioleoyloxy-3-trimethylammoniumpropane chloride Cationics DOTAP Chloride

Cationics DOTAP Chloride
1,2-dioleoyloxy-3-(trimethylammonium)propane chloride or Cationics DOTAP Chloride or N-[1-(2,3-Dioleoyloxy)propyl]-N,N,N-trimethylammonium chloride.

1,2-dioleoyloxy-3-trimethylammoniumpropane chloride or Cationics DOTAP Chloride or N-[1-(2,3-Dioleoyloxy)propyl]-N,N,N-trimethylammonium chloride has been used for the preparation of cationic liposome and liposome-DNA complex. 1,2-dioleoyloxy-3-(trimethylammonium)propane (DOTAP) chloride is useful in liposome preparation, without the use of helper lipid. 1,2-Dioleoyl-3-trimethylammonium-propane, Chloride is a compound useful in organic synthesis. 1,2-Dioleoyl-3-trimethylammoniumpropane (DOTAP) is a cationic liposome-forming compound used for transfection of DNA, RNA, and other negatively charged molecules into eukaryotic cells. It has been used in the composition of small unilamellar liposomes formulated as a gene delivery vectors for gene therapy.

General Properties and Specifications of 1,2-dioleoyloxy-3-(trimethylammonium)propane chloride or Cationics DOTAP Chloride or N-[1-(2,3-Dioleoyloxy)propyl]-N,N,N-trimethylammonium chloride:
CAS number: 132172-61-3 alternate 113669-21-9
Molecular formula: C42H80ClNO4
Molecular weight: 698.54
Appearance: White to Off-white powder.
Assay: 99% minimum for undiluted material.
Solubility: Chloroform (Slightly), Methanol (Slightly).
Storage: -20C. Short term shipping may be at preferably with dry ice.

For Original Monographs of IP Indian Pharmacopoeia BP British Pharmacopoeia USP US Pharmacopoeia FCC Food Grade product, please check with the respective web-pages or books.

We manufacture ansd supply as under:

1,2-Dioleyloxy-3-dimethylamino-propane or Cationics DODMA

1,2-Dioleoyloxy-3-trimethylammoniumpropane chloride or Cationics DOTAP Chloride

Manufacturers:

MUBY CHEMICALS
Ambernath Mumbai, Ankleshwar Gujarat, India
TEL: (OFFICE) +912223770100, +912223726950
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e-mail: info@mubychem.com

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Last 24 August, 2022

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1,2-Dioleoyloxy-3-trimethylammoniumpropane chloride or Catatonics DOTAP Chloride or N-[1-(2,3-Dioleoyloxy)propyl]-N,N,N-trimethylammonium chloride SDS, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet
25-Nov-20

Section 1: Chemical Product Identification

Product Name & Other Names: 1,2-Dioleoyloxy-3-trimethylammoniumpropane chloride or catatonics DOTAP Chloride or N-[1-(2,3-Dioleoyloxy)propyl]-N,N,N-trimethylammonium chloride.
CAS#: 132172-61-3 alternate 113669-21-9
EINECS EC Number: NA
Molecular Weight: 698.54
Chemical Formula: C42H80ClNO4
Relevant uses and uses advised against (if any): Industrial Manufacturing.
Suppliers: As per letterhead.

Section 2: Hazards Identification

GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008

Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
This substance is not classified as dangerous according to Directive 67/548/EEC.

Labeling according to GHS & Regulation (EC) No 1272/2008

GHS Label Elements
None

Signal Words: None

Hazards not otherwise classified (HNOC):
May causes mild skin irritation.
May causes mild eye irritation.

Precautionary statements:
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P262: Do not get in eyes, on skin, or on clothing.
P281: Use personal protective equipment as required.
P302+P352 - IF ON SKIN: Wash with plenty of soap and water.
P303+P361+P353 - IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
P304 + P340 - IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+313: If eye irritation persists get medical advice/attention.

Section 3: Composition and Information on Ingredients

Product Name & Other Names: 1,2-Dioleoyloxy-3-trimethylammoniumpropane chloride or cationic DOTAP Chloride or N-[1-(2,3-Dioleoyloxy)propyl]-N,N,N-trimethylammonium chloride.
CAS#: 132172-61-3 alternate 113669-21-9
EINECS EC Number: NA.

Section 4: First Aid Measures

Always get medical attention after the first aid is over.

Eye Contact: Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Get medical attention if irritation occurs.
Skin Contact: Wash with soap and water. Cover the irritated skin with an emollient. Get medical attention if irritation develops.
Inhalation: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.
Ingestion: Do Not induce vomiting unless directed to do so by medical personnel. If large quantities of this material are swallowed, call a physician immediately. Loosen tight clothing.
Notes to Physician: Provide general supportive measures and treat symptomatically.

Section 5: Fire and Explosion Data

Flammability of the Product: Not classed as fire hazard but it may be combustible at high temperature.
Auto-Ignition Temperature: Not available.
Products of Combustion: Oxides of carbon, hydrogen chloride, nitrogen oxides and ammonia along with fumes .
Fire Fighting Media and Instructions: Use DRY chemical powder, water spray, carbon dioxide, fog or foam. Do not use water jet. Fire-extinguishing work is done from the windward and the suitable fire-extinguishing method according to the surrounding situation is used. Uninvolved persons should evacuate to a safe place. In case of fire in the surroundings: Remove movable containers if safe to do so.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes. Fire-extinguishing work is done from the windward and the suitable fire-extinguishing method according to the surrounding situation is used. Uninvolved persons should evacuate to a safe place.

Section 6: Accidental Release Measures

Personal precautions, protective equipment and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Ensure adequate ventilation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil or water sources.
Methods and materials used for containment Cleanup procedures and Storage:
Small Spill: Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to legal requirements.
Large Spill: Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and allow to drain or as required by law. Use personal protective equipment. Keep people away from and upwind of spill/leak. Entry to non-involved personnel should be controlled around the leakage area by roping off, etc.

Section 7: Handling and Storage

Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. Wash thoroughly after handling. Do not drink, eat or smoke while handling. Avoid contact with skin, eyes and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cold, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Do not leave the material container open. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like oxidizing agents. Storage: -20C. Short term shipping may be at preferably with dry ice.

Section 8: Exposure Controls/Personal Protection

Engineering Controls: Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits.
Exposure Limits: Not established.
Respiratory protection: Dust mask or appropriate respirator. Utilize local exhaust ventilation.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Dust deposits on floors and other surfaces may pick up moisture and cause the surfaces to become slippery and present safety hazards. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.

Section 9: Physical and Chemical Properties

Physical state and appearance: White to Off-white powder.
Odor: Not available.
Odor threshold: Not available.
pH: Not available.
Relative density: Not available.
Boiling Point: Not available.
Melting Point: Not available.
Flash point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility: Chloroform (Slightly), Methanol (Slightly).
Viscosity: Not available.
Molecular Weight: 698.54
Chemical Formula: C42H80ClNO4

Section 10: Stability and Reactivity Data

Stability: Stable under normal conditions.
Incompatibility with various substances: Oxidizing agents light and heat.
Hazardous Decomposition Products: May form nitrogen oxides, carbon dioxide and carbon monoxide and ammonia, hydrogen chloride and various hydrocarbon fume.
Polymerization: Will not occur.

Section 11: Toxicological Information

Toxicity to Animals: Not available.
Germ cell mutagenicity: No data available.
Reproductive toxicity: No data available.
Carcinogenicity: The substance is not a known carcinogen as per any authorized agency.

Section 12: Ecological Information

Toxicity to fish: Not available
BOD5 and COD: Not available.
Products of Biodegradation:
Possibly hazardous short-term degradation products are not likely. However, long term degradation products may arise.
Toxicity of the Products of Biodegradation: Not available.
Bio accumulative potential: Readily biodegradable.
Mobility in soil: No data available. Expected to be mobile due to water solubility.
Results of PBT and vPvB assessment: Not available.

Section 13: Disposal Considerations

Waste Disposal: To be disposed as per legal requirement.

Section 14: Transport Information

DOT USA, TDG Canada & ADR/RID Europe: Not regulated.
IMDG/IMO: Not regulated.
IATA/ICAO: Not regulated.

Section 15: Other Regulatory Information

USA Federal and State Regulations:
SARA 302: Not subject to the reporting requirements of SARA Title III, Section 302.
SARA 313: Not listed.
SARA 311/312 Hazards: No SARA Hazards.
California Prop. 65 Components: This product does not contain any chemicals known to State of California to cause cancer, birth defects, or any other reproductive harm.

Section 16: Other Information

Disclaimer:
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Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
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