Salicylic Acid or 2-Hydroxybenzoic Acid USP IP BP Ph Eur EP Reagent Manufacturers, with SDS GHS MSDS Sheet

Supplier, Manufacturer, Exporter of Salicylic Acid USP BP Ph Eur IP EP, Muby Chemicals of Mubychem Group, established in 1976, is the original manufacturers of Specialty Chemicals, Pharmaceutical Excipient, Fragrance Food & Flavor chemicals, Reagent Grade Chemicals, Shale Gas Fracturing Chemicals in India. Mubychem Group has several manufacturing facilities spread across Western India and world wide contacts and toll manufacturers. We are exporting globally to countries like USA, Canada, Europe, UAE, South Africa, Tanzania, Kenya, Egypt, Nigeria, Cameroon, Uganda, Turkey, Mexico, Brazil, Chile, Argentina, Dubai, Korea, Vietnam, Thailand, Malaysia, Indonesia, Australia, China, Germany, France, Italy, Portugal, Bangladesh, etc.

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Salicylic Acid or 2-Hydroxybenzoic Acid: CAS Number: 69-72-7, EINECS EC Number: 200-712-3, Molecular Formula: C7H6O3, Molecular Weight: 138.12, HS Code ---**

Specifications, Safety Data Sheet, Manufacturing process details, Wholesale retail buy sell prices, Uses etc available on line in these pages for Salicylic Acid or 2-Hydroxybenzoic Acid.

Salicylic acid is used in the production of other pharmaceuticals. Salicylic acid as a medication is used most commonly to help remove the outer layer of the skin. As such, it is used to treat warts, psoriasis, acne vulgaris, ringworm, dandruff, and ichthyosis. Salicylic acid is also used as a food preservative, bactericide, and an antiseptic.

Salicylic Acid BP Ph Eur Specifications:
C7H6O3 --- 138.1 --- CAS 69-72-7
Action and use: Keratolytic.

DEFINITION
2-Hydroxybenzenecarboxylic acid.
Content: 99.0 per cent to 100.5 per cent (dried substance).

CHARACTERS
Appearance: White or almost white, crystalline powder or white or colourless, acicular crystals.
Solubility: Slightly soluble in water, freely soluble in ethanol (96 per cent), sparingly soluble in methylene chloride.

IDENTIFICATION
First identification: A, B
Second identification: A, C
A. Melting point: 158C to 161C.
B. Infrared absorption spectrophotometry
C. Dissolve about 30 mg in 5 mL of 0.05 M sodium hydroxide, neutralise if necessary and dilute to 20 mL with water. 1 mL of the solution gives reaction (a) of salicylates.

TESTS
Solution S: Dissolve 2.5 g in 50 mL of boiling distilled water, cool and filter.
Appearance of solution: The solution is clear and colourless.
Dissolve 1 g in 10 mL of ethanol (96 per cent).Related substances: To pass the test.
Chlorides: Maximum 100 ppm.
Sulfates: Maximum 200 ppm.
Loss on drying: Maximum 0.5 per cent, determined on 1.000 g by drying in a desiccator.
Sulfated ash: Maximum 0.1 per cent, determined on 2.0 g.

Salicylic Acid USP Grade Specifications:
C7H6O3 --- 138.12
Benzoic acid, 2-hydroxy-
Salicylic acid CAS 69-72-7

DEFINITION
Salicylic Acid contains NLT 98.0% and NMT 102.0% of salicylic acid (C7H6O3 ), calculated on the dried basis.

IDENTIFICATION
A. Infrared Absorption
B. The retention time of the major peak of the Sample solution corresponds to that of the Standard solution, as obtained in the Assay.

Acceptance criteria: 98.0%–102.0% on the dried basis.
Residue on Ignition: NMT 0.05%
Chloride and Sulfate:
Chloride: To pass the test (0.014%).
Sulfate: To pass the test (0.02%).
Organic Impurities: To pass the test.
Loss on Drying:
Analysis: Dry over silica gel for 3 h.
Acceptance criteria: NMT 0.5%

Salicylic Acid Analytical Reagent Grade:
2-Hydroxybenzoic Acid
C7H6O3 --- Formula Weight 138.12
CAS Number 69-72-7

For Original Monographs of IP Indian Pharmacopoeia BP British Pharmacopoeia USP US Pharmacopoeia FCC Food Grade product, please check with the respective web-pages or books.

MUBY CHEMICALS
Ambernath Mumbai, Ankleshwar Gujarat, India
TEL: (OFFICE) +912223770100, +912223726950
Current Date Time in India GMT+5:30

USA, Canada, Mexico and other American
neighbouring buyers may
e-mail: us@mubychem.com
Call toll-free 1-877-682-9243 (1-877-MUBYCHEM)

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Salicylic Acid or 2-Hydroxybenzoic Acid or 2-Hydroxybenzenecarboxylic acid SDS, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet 12-Jun-21

Product Name & Other Names: Salicylic Acid or 2-Hydroxybenzoic Acid or 2-Hydroxybenzenecarboxylic acid.
CAS Number: 69-72-7
EINECS EC Number: 200-712-3
Molecular Formula: C7H6O3
Molecular Weight: 138.12
Relevant uses and uses advised against (if any): Industrial Manufacturing.
Suppliers: As per letterhead.

GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008

Acute toxicity, Oral Category 4 - H302
Serious eye damage Category 1 - H318
Reproductive toxicity Category 2 - H361

Hazard Statements:
H302: Harmful if swallowed.
H318: Causes serious eye damage.
H361: Suspected of damaging fertility or the unborn child.

Precautionary Statements:
P260: Do not breathe dust/fume/gas/mist/vapors/spray.
P262: Do not get in eyes, on skin, or on clothing.
P264: Wash contaminated parts thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P273: Avoid release to the environment.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310: IF SWALLOWED: Immediately call a POSION CENTER or doctor/physician.
P314: Get medical advice/attention if you feel unwell.
P305+351+338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do – continue rinsing.
P360: Rinse immediately contaminated clothing and skin with plenty of water before removing clothes.
P403 P404: Store in well-ventilated place. Keep container tightly closed.
P501: Dispose of contents/container in accordance with local/national regulation.

Classification according to EU Directives 67/548/EEC or 1999/45/EC:
Hazard Symbol:
C Corrosive
Xn Harmful
Risk Phrase:
R22 Harmful if swallowed.
R41 Risk of serious damage to eyes.
R60 May impair fertility.
R61 May cause harm to the unborn child.

Product Name & Other Names: Salicylic Acid or 2-Hydroxybenzoic Acid or 2-Hydroxybenzenecarboxylic acid.
CAS Number: 69-72-7
EINECS EC Number: 200-712-3

Inhalation: Remove affected person to fresh air; if normal breathing has not returned within a few minutes after exposure, get medical attention.
Skin: Remove contaminated clothing; wash affected area with soap and water; launder contaminated clothing before reuse. Seek medical attention.
Eyes: Immediately, flush eyes for 15 minutes in clear running water while holding eyelids open; seek medical attention immediately.
Ingestion: Drink two glasses of water followed by milk, milk of magnesia or other non-alcoholic liquids; Do not induce vomiting; seek medical attention immediately.

General Hazards: Contact with eyes causes immediate severe irritation of the eye and eyelids. Product will burn at high temperature.
Extinguishing Media: Carbon dioxide, dry chemical, chemical foam water fog. Do not use a heavy water stream. Keep containers cool by spraying with water. Use extinguishing media appropriate for surrounding fire.
Fire & Explosion Hazard: May evolve oxides of carbon (COx) and fumes under fire conditions.
Unusual Fire and Explosion Hazards: Closed containers can explode due to buildup of pressure when exposed to extreme heat. Cool containers to prevent pressure buildup and possible explosion when exposed to extreme heat.
Hazardous Combustion Products: Products of combustion include smoke, toxic fumes, oxides of carbon to include carbon monoxide.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes. Fire-extinguishing work is done from the windward and the suitable fire-extinguishing method according to the surrounding situation is used. Uninvolved persons should evacuate to a safe place.

Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach, facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter sewer, soil, or water sources.
Methods and materials used for containment Clean-up procedures and Storage: Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g., sand, earth, diatomaceous earth, vermiculite). Vacuum or sweep up and remove to an approved disposal container. It will support combustion. For large spills, confine spill, cover up with approved absorbent, shovel product into approved container for disposal.

Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Do not leave the material container open. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like strong oxidizing agent. Keep container closed when not in use; protect containers from abuse; protect from extreme temperatures, open flames.

Exposure Guidelines: OSHA PEL TWA 15 mg/m3 Total Dust.
Engineering Controls: The use of local exhaust ventilation is recommended to control emissions near the source. Provide mechanical ventilation of confined spaces. Use corrosion-resistant, explosion-proof ventilation equipment.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full-face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Dust deposits on floors and other surfaces may pick up moisture and cause the surfaces to become slippery and present safety hazards. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.

Appearance: White or almost white, crystalline powder or white or colorless, acicular crystals.
Odor: Odorless.
Odor threshold: Not applicable.
pH: 2.4 @ 20C.
Relative density: around 1.44
Melting point/freezing point: 158-161C literature.
Boiling Point: 211C literature.
Flash point: 157C literature.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor Pressure (MM Hg): Not available.
Vapor Density (Air = 1) : Not available.
Evaporation Rate (water = 1) : Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility in Water: Slightly soluble in water, freely soluble in ethanol (96 per cent), sparingly soluble in methylene chloride.
Viscosity: Not available.
Molecular Formula: C7H6O3
Molecular Weight: 138.12

Stability: Stable at normal temperatures and operating conditions. Sensitivity to light. Sublimable.
Conditions to Avoid: Avoid excessively high temperatures and contact with strong oxidizing agents. Direct sunlight. Air contact.
Incompatibilities: Strong oxidizing agent.
Decomposition: Decomposition yields carbon monoxide & dioxide and fumes.
Polymerization: Polymerization will not occur.

LD50 Oral Rat: 891 mg/kg.
LD50 Dermal Rat: > 2,000 mg/kg
Reproduction: Suspected of damaging fertility. Suspected of damaging the unborn child.
Carcinogenicity: Not listed as a human carcinogen by OSHA, IARC, ACGIH & NTP.
Acute Toxicity: Not available.

Toxicity to fish: flow-through test LC50 - Pimephales promelas (fathead minnow) - 1.370 mg/l - 96 hours.
Toxicity to daphnia and other aquatic invertebrates: static test EC50 - Daphnia magna (Water flea) - 870 mg/l - 48 hours
Persistence and Degradability: Inherently biodegradable.
Mobility: No information available.
Bioaccumulation/ Accumulation: No information available.
Results of PBT and vPvB assessment: No data available for assessment.

Dispose of in accordance with Local, State, and Federal Regulations. Consult local, state, or Federal Environmental Protection Agency before disposing of any chemicals.

DOT USA, TDG Canada & ADR/RID Europe: Not dangerous goods.
IMDG/IMO & IATA/ICAO: Not dangerous goods.

European Labeling in Accordance with EC Directives:
H302: Harmful if swallowed.
H318: Causes serious eye damage.
H361: Suspected of damaging fertility or the unborn child.

Disclaimer:
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Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
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