Piperazine Adipate BP Ph Eur USP Grade Manufacturers, with SDS GHS MSDS Sheet

Supplier, Manufacturer, Exporter of Piperazine Adipate, Muby Chemicals of Mubychem Group, established in 1976, is the original manufacturers of Specialty Chemicals, Pharmaceutical Excipient, Fragrance Food & Flavor chemicals, Reagent Grade Chemicals, Shale Gas Fracturing Chemicals in India. Mubychem Group has several manufacturing facilities spread across Western India and world wide contacts and toll manufacturers. We are exporting globally to countries like USA, Canada, Europe, UAE, South Africa, Tanzania, Kenya, Egypt, Nigeria, Cameroon, Uganda, Turkey, Mexico, Brazil, Chile, Argentina, Dubai, Korea, Vietnam, Thailand, Malaysia, Indonesia, Australia, China, Germany, France, Italy, Portugal, Bangladesh, etc.

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Piperazine Adipate or Adiprazina or Adiprazine CAS Number 142-88-1, EINECS EC Number: 205-569-0, Molecular Formula: C6H10O4-C4H10N2 or C10H20N2O4, Molecular Weight: 232.28, HS Code 29334900

Specifications, Safety Data Sheet, Manufacturing process details, Wholesale retail buy sell prices, Uses etc available on line in these pages for Piperazine Adipate or Adiprazina or Adiprazine.

Piperazine adipate appears as odorless white crystalline powder or solid. It is used in pharmaceutical industries.

General Properties and Specifications of Piperazine Adipate or Adiprazina or Adiprazine:
Appearance: White crystalline powder.
Melting point: 256C to 257C literature.
pH (5% solution): 5 to 6.
Solubility: Soluble in water.

Piperazine Adipate USP Grade Specifications:
C4H10N2- C6H10O4 -- 232.28
Piperazine, compound with 1,4-butanediacarboxylic acid (1:1).
Piperazine, compound with hexanedioic acid (1:1) CAS 142-88-1

Piperazine Adipate contains not less than 98.0 percent and not more than 101.0 percent of C4H10N2-C6H10O4, calculated on the anhydrous basis.

Packaging and storage: Preserve in well-closed containers, and store at room temperature.
Identification:
A: Infrared Absorption
B: In the test for Chromatographic purity, the principal spot in the chromatogram obtained from Test solution 2 observed after spraying with the ninhydrin solutions corresponds in R F value, color, and size to that in the chromatogram obtained from Standard solution 1.
C: To 10 mL of a 1 in 20 solution of it add 5 mL of hydrochloric acid, and extract with three 10-mL portions of ether. Evaporate the combined ether extracts to dryness, wash the residue with water, and dry at 105°: the residue of adipic acid so obtained melts at between 150C and 154C.

Water Determination: Not more than 0.5%.
Residue on ignition: Not more than 0.1%.
Chromatographic purity: To pass the tese.
Assay: Dissolve about 100 mg of Piperazine Adipate, accurately weighed, in 10 mL of glacial acetic acid, heating gently if necessary. Add 60 mL of glacial acetic acid and 0.25 mL of p-naphtholbenzein and titrate with 0.1 N perchloric acid until the brownish-yellow color of the solution turns green. Each mL of 0.1 N perchloric acid is equivalent to 11.61 mg of C4H10N2-C6H10O4.

Piperazine Adipate BP Ph Eur Grade Specifications:
C10H20N2O4 -- 232.3 – CAS 142-88-1
Action and use: Anthelminthic.

DEFINITION
Piperazine adipate contains not less than 98.0 per cent and not more than the equivalent of 101.0 per cent of piperazine hexanedioate, calculated with reference to the anhydrous substance.

CHARACTERS
A white or almost white crystalline powder, soluble in water, practically insoluble in alcohol. It melts at about 250C, with decomposition.

IDENTIFICATION
First identification: A
Second identification: B, C
A. Examine by infrared absorption spectrophotometry, comparing with the spectrum obtained with piperazine adipate CRS. Examine the substances prepared as discs.
B. Examine the chromatograms obtained in the test for related substances after spraying with the ninhydrin solutions. The principal spot in the chromatogram obtained with test solution (b) is similar in position, colour and size to the principal spot in the chromatogram obtained with reference solution (a).
C. To 10 mL of solution S add 5 mL of hydrochloric acid and shake with three quantities, each of 10 mL of ether. Evaporate the combined ether layers to dryness. The residue, washed with 5 mL of water and dried at 100C to 105C, melts at 150C to 154C.

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Piperazine Adipate or Adiprazina or Adiprazine SDS Sheet, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet 25-Mar-22

Product Name & Other Names: Piperazine Adipate or Adiprazina or Adiprazine.
CAS No.: 142-88-1
EINECS EC Code: 205-569-0
Molecular Weight: 232.28
Chemical Formula: C6H10O4-C4H10N2 or C10H20N2O4
Relevant uses and uses advised against (if any): Industrial Manufacturing.
SUPPLIER: As per letterhead.

GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008

Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
This substance is not classified as dangerous according to Directive 67/548/EEC.

Hazards not otherwise classified (HNOC):
May cause mild skin irritation.
May cause mild eye irritation.
May cause mild respiratory irritation.

Precautionary statements:
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P262: Do not get in eyes, on skin, or on clothing.
P281: Use personal protective equipment as required.
P302+P352: IF ON SKIN: Wash with plenty of soap and water.
P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+313: If eye irritation persists get medical advice/attention.

Product Name & Other Names: Piperazine Adipate or Adiprazina or Adiprazine.
CAS No.: 142-88-1
EINECS EC Code: 205-569-0

Inhalation: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.
Ingestion: Contact medical center quickly. Never give anything by mouth to an unconscious person. Get medical attention.
Skin Contact: Immediately flush skin with plenty of water for at least 15 minutes. Remove contaminated clothing and shoes. Get medical attention. Wash clothing before reuse. Thoroughly clean shoes before reuse.
Eye Contact: Check for and remove any contact lenses. Immediately flush eyes with running water for at least 15 minutes, keeping eyelids open. Cold water may be used. Get medical attention.

Combustible at high temperature. High heat or direct flame is necessary to cause ignition. Toxic fumes, carbon monoxide and nitrogen oxides may be formed in fire.
Explosion: At high temperature, explosive vapor-air mixtures may be formed.
Fire Extinguishing Media: Dry chemical, foam, water spray or carbon dioxide. Do not use a solid stream of water since the stream will scatter and spread the fire. Water spray may be used to keep fire exposed containers cool.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes. Fire-extinguishing work is done from the windward and the suitable fire-extinguishing method according to the surrounding situation is used. Uninvolved persons should evacuate to a safe place.

Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment cleanup procedures and Storage:
Small Spill: Mop and pick up the material and place in an appropriate waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to local and regional authority requirements.
Large Spill: Avoid dust formation. Keep away from heat. Keep away from sources of ignition. Provide ventilation. Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g., sand, earth, diatomaceous earth, vermiculite). Vacuum or sweep-up and remove to an approved disposal container.

Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Keep away from heat and source of fire. Store in cold, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Do not breathe dust. Do not leave the material container open. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like oxidizing material.

Airborne Exposure Limits: The product does not contain any relevant quantities of materials with critical values that have to be monitored at the workplace.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area. Please refer to the ACGIH document, Industrial Ventilation, A Manual of Recommended Practices, most recent edition, for details.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to the substance is apparent and engineering controls are not feasible, consult an industrial hygienist. For emergencies, or instances where the exposure levels are not known, use a full-face piece positive-pressure, air-supplied respirator. WARNING: Air purifying respirators do not protect workers in oxygen-deficient atmospheres.
Skin Protection: Wear impervious protective clothing, including boots, gloves, lab coat, apron, or coveralls, as appropriate, to prevent skin contact.
Eye Protection: Use chemical safety goggles and/or a full-face shield where splashing is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Dust deposits on floors and other surfaces may pick up moisture and cause the surfaces to become slippery and present safety hazards. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.

Appearance: White crystalline powder.
Odor: Not available.
Odor threshold: Not available.
pH: 5 to 6 for 5% solution
Melting point: 256C to 257C literature.
Boiling point: Not available.
Relative density: Not available.
Flash point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility: Soluble in water.
Viscosity: Not available.
Molecular Weight: 232.28
Chemical Formula: C6H10O4-C4H10N2 or C10H20N2O4.

Stability: Stable under ordinary conditions of use and storage.
Hazardous Decomposition Products: Carbon dioxide, carbon monoxide, nitrogen oxides and toxic fumes may form when heated to decomposition.
Hazardous Polymerization: Not reported. However, it can explode under certain conditions.
Incompatibilities: Oxidizing agents, heat, and sparks.
Conditions to Avoid: Heat, flames, sunlight, ignition sources and incompatibles.

Oral Mouse LD50: 8g/kg.
Carcinogenicity: No component of this product present at levels greater than or equal to 0.1% is identified as possible or confirmed human carcinogen by IARC, ACGIH, OSHA and NTP.
Teratogenic Effects: Not available.
Mutagenic Effects: Not available.
Developmental Toxicity: Not available.
Reproductive Effects: No information available.

Toxicity to fish: No information available.
Mobility: Likely to be mobile.
Biodegradability: Expected to be biodegradable
Results of PBT and vPvB assessment: No data available for assessment.

Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. Processing use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose of container and unused contents in accordance with federal, state, and local requirements.

DOT USA & ADR/RID Europe: Not regulated
IMDG/IMO: Not regulated
IATA/ICAO: Not regulated.

USA:
SARA 311/312 Hazards: No. See section 2.
California Prop. 65 Components: This product does not contain any chemicals known to State of California to cause cancer, birth defects, or any other reproductive harm.

Disclaimer:
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Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
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