Adipic Acid Pure and EP IP BP Ph Eur USP NF FCC Food Grade Manufacturers, SDS GHS MSDS Sheet

Supplier, Manufacturer, Exporter of Adipic Acid EP IP BP Ph Eur USP NF FCC Food Grade, Muby Chemicals of Mubychem Group, established in 1976, is the original manufacturers of Specialty Chemicals, Pharmaceutical Excipient, Fragrance Food & Flavor chemicals, Reagent Grade Chemicals, Shale Gas Fracturing Chemicals in India. Mubychem Group has several manufacturing facilities spread across Western India and world wide contacts and toll manufacturers. We are exporting globally to countries like USA, Canada, Europe, UAE, South Africa, Tanzania, Kenya, Egypt, Nigeria, Cameroon, Uganda, Turkey, Mexico, Brazil, Chile, Argentina, Dubai, Korea, Vietnam, Thailand, Malaysia, Indonesia, Australia, China, Germany, France, Italy, Portugal, Bangladesh, etc.

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Adipic Acid: CAS Number: 124-04-9, EINECS EC Number: 204-673-3, Molecular Formula: C6H10O4, Molecular Weight: 146.14, HS Code ---**

Specifications, Manufacturing process details, Wholesale retail prices, Uses etc available on these pages for Adipic Acid.

Adipic acid or hexanedioic acid is the organic compound with the formula (CH2)4(COOH)2. From an industrial perspective, it is the most important dicarboxylic acid. Adipic acid otherwise rarely occurs in nature, but it is known as manufactured E number food additive E355. Adipic acid has been incorporated into controlled-release formulation matrix tablets to obtain pH-independent release for both weakly basic and weakly acidic drugs. significant amounts of adipic acid are used as a food ingredient as a flavorant and gelling aid.

Specifications of Adipic Acid Commercial Pure:
Appearance: It occurs as a white crystalline powder.
Melting point: Not less than 151.5 C
Moisture: Not more than 0.2%
Ammonia solution color (PT-CO): Not more than 5
Iron (Fe): Not more than 0.4 mg/kg
Nitric acid (HNO3): Not more than 3 mg/kg
Ashes: Not more than 4 mg/kg
Assay: Not less than 99.7%.

Adipic Acid BP Grade
Ph Eur
C6H10O4 --- 146.1 --- CAS 124-04-9
Action and use: Excipient.

DEFINITION
Hexanedioic acid.
Content: 99.0 per cent to 101.0 per cent (dried substance).

CHARACTERS
Appearance: White or almost white, crystalline powder.
Solubility: Sparingly soluble in water, soluble in boiling water, freely soluble in alcohol and in methanol, soluble in acetone.

IDENTIFICATION
A. Melting point (2.2.14): 151C to 154C.
B. Infrared absorption spectrophotometry.

TESTS
Solution S: Dissolve 5.0 g with heating in distilled water and dilute to 50 ml with the same solvent. Allow to cool and to crystallise. Filter through a sintered-glass filter (40). Wash the filter with distilled water. Collect the filtrate and the washings until a volume of 50 ml is obtained.
Appearance of solution: The solution is clear and colourless.
Dissolve 1.0 g in methanol R and dilute to 20 ml with the same solvent.
Related substances: Liquid chromatography To pass the test.
Chlorides: Maximum 200 ppm.
Nitrates: Maximum 30 ppm.
Sulphates: Maximum 500 ppm.
Iron: Maximum 10 ppm.
Heavy metals: Maximum 10 ppm.
Loss on drying: Maximum 0.2 per cent, determined on 1.000 g by drying in an oven at 105C.
Sulphated ash: Maximum 0.1 per cent.

Adipic Acid USP NF Grade
C6H10O4 --- 146.1
Hexanedioic acid.
1,4-Butanedicarboxylic acid CAS 124-04-9

Adipic Acid contains not less than 99.0 percent and not more than 101.0 percent of C6H10O4, calculated on the dried basis.
Packaging and storage: Preserve in a tight container. No storage requirements specified.
Identification: Infrared Absorption 197K .
Melting range: between 151C and 154C.
Loss on drying: Dry it at 105C to constant weight: it loses not more than 0.2% of its weight.
Residue on ignition: not more than 0.1%.
Limit of nitrates: To pass the test
Chloride: A 5-mL portion of the Test solution from the Limit of nitrates test shows no more chloride than a corresponding 0.14-mL portion of 0.020 N hydrochloric acid: the limit is 0.02%.
Sulfate: A 5-mL portion of the Test solution from the Limit of nitrates test shows no more sulfate than a corresponding 0.26-mL portion of 0.020 N sulfuric acid: the limit is 0.05%.
Iron: Use a 10-mL portion of the Test solution from the Limit of nitrates test: the limit is 0.001%.
Heavy metals: 0.001%.

Adipic Acid FCC Food Grade
Hexanedioic Acid; 1,4-Butanedicarboxylic Acid
HOOC(CH2)4COOH
C6H10O4 Formula weight 146.14
INS: 355 CAS 124-04-9

DESCRIPTION
Adipic Acid occurs as white crystals or a crystalline powder. It is not hygroscopic. It is freely soluble in alcohol, soluble in acetone, and slightly soluble in water.
Function: Buffer; neutralizing agent.

For Original Monographs of IP Indian Pharmacopoeia BP British Pharmacopoeia USP US Pharmacopoeia FCC Food Grade product, please check with the respective web-pages or books.

MUBY CHEMICALS
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Product Name & Other Names: Adipic Acid or Hexanedioic acid.
CAS Number: 124-04-9
EINECS EC Number: 204-673-3
Molecular Formula: C6H10O4
Molecular Weight: 146.14
Relevant uses and uses advised against (if any): Industrial Manufacturing.
Supplier: As per the letterhead.

GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008

Hazard statements:
H318: Causes serious eye damage.
Precautionary statements:
P261: Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray.
P262: Do not get in eyes, on skin, or on clothing.
P264 Wash skin thoroughly after handling.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Classification according to European Directive 67/548/EEC as amended:
Hazard symbol:
Xn Harmful
R-phrase:
R41 Risk of serious damage to eyes.

Product Name & Other Names: Adipic Acid or Hexanedioic acid.
CAS Number: 124-04-9
EINECS EC Number: 204-673-3

Eye Contact: Do not allow victim to rub eye (s). Let the eye (s) water naturally for a few minutes. If particle/dust does not dislodge, flush with lukewarm, gently flowing water for 5 minutes or until particle/dust is removed, while holding eyelid (s) open. If irritation persists, obtain medical attention. DO NOT attempt to manually remove anything stuck to the eye.
Skin Contact: Remove contaminated clothing, shoes, and leather goods (e.g. watchbands, belts). Quickly and gently blot or brush away excess chemical. Wash gently and thoroughly with lukewarm gently flowing water and non-abrasive soap for 5 minutes. If irritation persists, repeat flushing. Obtain medical advice. Completely decontaminate clothing, shoes and leather goods before reuse or else discard.
Inhalation: If symptoms are experienced, remove source of contamination or move victim to fresh air. Obtain medical advice.
Ingestion: Never give anything by mouth if victim is rapidly losing consciousness or is unconscious or convulsing. Have victim rinse mouth thoroughly with water. DO NOT INDUCE VOMITING.

Fire and Explosion Hazards: Not considered flammable but may burn at high temperatures. Airborne dusts of this product in an enclosed space and in the presence of an ignition source may constitute an explosion hazard.
Extinguishing Media: Use means of extinction appropriate for the surrounding fire conditions such as water spray, carbon dioxide, dry chemical, or foam.
Fire Fighting: Apart from oxides of carbon, toxic fumes may result from combustion. As with any fire, fire fighters should be fully trained and wear full protective clothing including an approved, self-contained breathing apparatus which supplies a positive air pressure within a full-face piece mask. Use water spray to cool unopened containers.

Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material. Close-fitting safety goggles may be necessary in some circumstances to prevent eye contact.
Environmental precautions: Do not let the product enter drains, soil or water sources.
Methods and materials used for containment Cleanup procedures and Storage: Contain spilled material. Contain spill, isolate hazard area, and deny entry. Sweep up or vacuum. Place contaminated material in suitable, labeled containers for final disposal. Dispose of waste material consistent with the requirements of waste disposal authorities.

Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Do not leave the material container open. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like oxidizing agents, strong reducing agents, and bases. Keep away from sources of ignition. Take measures to prevent the build-up of electrostatic charge. It is good practice to keep container closed when not in use. May form combustible dust concentrations in air. Use care during processing to minimize generation of dust. Good housekeeping is important to prevent accumulations of dust.

Exposure limit(s): Contains no substances with occupational exposure limit values in some countries. Better go by 5 mg/m3 TLV ACGIH.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Dust deposits on floors and other surfaces may pick up moisture and cause the surfaces to become slippery and present safety hazards. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.

Appearance: It is a white, odorless granules crystals or powder
Odor: None
Odor threshold: Not available.
pH: 2.5 to 4
Relative density: 1.36
Freezing/Melting Point/Range: 151C to 154C
Boiling Point: Decomposes at 337C
Flash point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility in Water: Soluble in water.
Viscosity: Not available.
Molecular Formula: C6H10O4
Molecular Weight: 146.14

Stability and Reactivity: Stable and not considered reactive under normal temperatures and pressures. Hazardous polymerization or runaway reactions will not occur.
Incompatibilities: Oxidizing agents. Avoid excessive heat, spark, flame, ignition dust formation and electrical charging. Also avoid strong reducing agents and bases.
Hazardous Decomposition Products: High temperature will generate carbon oxide and fumes.

Acute Toxicity:
LD50 Oral - Rat - male and female - 5,560 mg/kg
LC0 Inhalation - Rat - male and female - 4 h - > 7.7 mg/l
LD0 Dermal - Rabbit - male and female - 7,940 mg/kg
Carcinogenicity: IARC: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity: Not Available.
Teratogenicity: Not Available
Mutagenicity: Not Available.

Toxicological data:
Toxicity to fish: static test LC0 - Brachydanio rerio (zebrafish) - >= 1,000 mg/l - 96 h.
Toxicity to daphnia and other aquatic invertebrates: Immobilization LC50 - Daphnia magna (Water flea) - 46 mg/l - 48 h.
Results of PBT and vPvB assessment: This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.

Do not wash the material down drain. Put uncontaminated material back into the process if possible. Place contaminated material in suitable, labeled containers for disposal. Dispose of waste material consistent with the requirements of waste disposal authorities.

DOT USA & ADR/RID Europe: Not regulated for transport.
IATA & IMDG: Not regulated for transport.

USA Regulations:
SARA 311/312 Hazards: Acute Health Hazard. See section 2.
SARA 313 Components: Not listed.
California Prop. 65 Components: Not listed.

European Labeling in Accordance with EC Directives
H318: Causes serious eye damage.

Disclaimer:
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Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
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