Tragacanth or Gum Tragacanth Manufacturers, with SDS GHS MSDS Sheet
Supplier, Manufacturer, Exporter of Tragacanth or Gum Tragacanth, Muby Chemicals of Mubychem Group, established in 1976, is the original manufacturers of Specialty Chemicals, Pharmaceutical Excipient, Fragrance Food & Flavor chemicals, Reagent Grade Chemicals, Shale Gas Fracturing Chemicals in India. Mubychem Group has several manufacturing facilities spread across Western India and world wide contacts and toll manufacturers. We are exporting globally to countries like USA, Canada, Europe, UAE, South Africa, Tanzania, Kenya, Egypt, Nigeria, Cameroon, Uganda, Turkey, Mexico, Brazil, Chile, Argentina, Dubai, Korea, Vietnam, Thailand, Malaysia, Indonesia, Australia, China, Germany, France, Italy, Portugal etc.
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Tragacanth or Gum Tragacanth: CAS Number: 9000-65-1, EINECS EC Number: 232-552-5, Molecular Formula: yy, Molecular Weight: yy, HS Code ---**
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SDS MSDS Sheet of Gum Tragacanth Manufacturers
Tragacanth Pure Suppliers
Tragacanth Gum is a natural gum obtained from the dried sap of several species of Middle Eastern legumes of the genus Astragalus. Gum tragacanth is a viscous, odorless, tasteless, water-soluble mixture of polysaccharides obtained from sap that is drained from the root of the plant and dried. The gum seeps from the plant in twisted ribbons or flakes that can be powdered. It absorbs water to become a gel, which can be stirred into a paste. The gum has been used historically as a herbal remedy for such conditions as cough and diarrhea. As a mucilage or paste, it has been used as a topical treatment for burns. It is used in pharmaceuticals and foods as an emulsifier, thickener, stabilizer, and texturant additive (E number E413). It is the traditional binder used in the making of artists' pastels. Gum tragacanth produces high-viscosity solutions (the highest of the exudate gums), but it takes up to 24 h of hydration to achieve maximum viscosity. Solutions of it are shear thinning. Like gum arabic, gum tragacanth is both an emulsifier and an emulsion stabilizer. It is rather acid stable. Gum tragacanth is an effective suspending agent for many pharmaceutical products. It generally acts to suspend the active ingredient by increasing the viscosity of the external phase and thus prevents undissolved material from settling out. Gum tragacanth is used in practice as a suspending agent in aqueous mixtures containing resinous tinctures and heavy insoluble powders. Glycerite of tragacanth is a useful excipient to bind tablet masses.
General Properties and Specifications of Gum Tragacanth:
Appearance: Off-white to light-yellow powder.
Karaya Gum: To pass the test.
Specifications of Tragacanth USP NF Grade:
Tragacanth is the dried gummy exudation from Astragalus gummifer Labill., or other Asiatic species of Astragalus (Fam. Leguminosae).
A. Add 1 g to 50 mL of water: it swells and forms a smooth, nearly uniform, stiff, opalescent mucilage free from cellular fragments.
Lead: NMT 10 ppm
Microbial Enumeration Tests and Tests for Specified Microorganisms: It meets the requirements for absence of Salmonella species and Escherichia coli.
Tragacanth: It is flattened, lamellated, frequently curved fragments or straight or spirally twisted linear pieces from 0.5 to 2.5 mm in thickness. It is white to weak yellow in color, translucent, and horny in texture. Its fracture is short. It is rendered more easily pulverizable by heating to 50C. It is odorless.
Histology: Pieces of Tragacanth softened in water and mounted in water or glycerin show numerous lamellae and a few starch grains.
Powdered tragacanth: It is white to yellowish white. When examined in water mounts, it shows numerous angular fragments of mucilage with circular or irregular lamellae, and occasional starch grains up to 25 µm in diameter, mostly simple, spherical to elliptical, with occasional two- to four-compound grains, a few of the grains being swollen and more or less altered. The powder shows few or no fragments of lignified vegetable tissue (Indian gum).
Sample solution: 1 g in 20 mL of water
Analysis: Boil the Sample solution until a mucilage is formed, add 5 mL of hydrochloric acid, and again boil the mixture for 5 min.
Acceptance criteria: No pink or red color develops.
Packaging and Storage: Preserve in well-closed containers.
Specifications of Tragacanth BP Ph Eur:
When Powdered Tragacanth is prescribed or demanded, material complying with the requirements below except for Identification test A shall be dispensed or supplied.
Air-hardened, gummy exudate, flowing naturally or obtained by incision from the trunk and branches of Astragalus gummifer Labill. and certain other species of Astragalus from western Asia.
A. Tragacanth occurs in thin, flattened, ribbon-like, white or pale yellow, translucent strips, about 30 mm long and 10 mm wide and up to 1 mm thick, more or less curved, horny, with a short fracture; the surface is marked by fine longitudinal striae and concentric transverse ridges. It may also contain pieces similar in shape but somewhat thicker, opaquer and more difficult to fracture.
B. Microscopic examination. The powder is white or almost white and forms a mucilaginous gel with about 10 times its mass of water. Examine under a microscope using a 50 per cent V/V solution of glycerol. The powder shows in the gummy mass numerous stratified cellular membranes that turn slowly violet when treated with iodinated zinc chloride solution. The gummy mass includes starch grains, isolated or in small groups, usually rounded in shape and sometimes deformed, with diameters varying between 4 µm and 10 micro-m, occasionally up to 20 µm, and a central hilum visible between crossed nicol prisms.
C. Examine the chromatograms obtained in the test for acacia.
Results The chromatogram obtained with the test solution shows 3 zones due to galactose, arabinose and xylose. A faint yellowish zone at the solvent front and a greyish-green zone between the zones due to galactose and arabinose may be present.
D. Moisten 0.5 g of the powdered herbal drug with 1 mL of ethanol (96 per cent) and add gradually, while shaking, 50 mL of water until a homogeneous mucilage is obtained. To 5 mL of the mucilage add 5 mL of water and 2 mL of barium hydroxide solution. A slight flocculent precipitate is formed. Heat on a water-bath for 10 min. An intense yellow colour develops.
Acacia: To pass the test by Thin-layer chromatography.
Methylcellulose: Examine the chromatograms obtained in the test for acacia.
Results The chromatogram obtained with the test solution does not show a red zone near the solvent front.
A. Place 0.2 g of the powdered herbal drug in a 10 mL ground-glass-stoppered cylinder graduated in 0.1 mL. Add 10 mL of ethanol (60 per cent V/V) R and shake. Any gel formed occupies not more than 1.5 mL.
B. To 1.0 g of the powdered herbal drug add 100 mL of water and shake. Add 0.1 mL of methyl red solution. Not more than 5.0 mL of 0.01 M sodium hydroxide is required to change the colour of the indicator.
Foreign matter: Maximum 1.0 per cent.
Place 2.0 g of the powdered herbal drug in a 250 mL round-bottomed flask and add 95 mL of methanol. Swirl to moisten the powder and add 60 mL of hydrochloric acid. Add a few glass beads about 4 mm in diameter and heat on a water-bath under a reflux condenser for 3 h, shaking occasionally. Remove the glass beads and filter the hot suspension in vacuo through a sintered-glass filter (160). Rinse the flask with a small quantity of water and pass the rinsings through the filter. Wash the residue on the filter with about 40 mL of methanol and dry to constant mass at 110 °C (about 1 h). Allow to cool in a desiccator and weigh. The residue weighs a maximum of 20 mg.
Flow time: Minimum 10 s, or minimum 50 s if the substance to be examined is to be used for the preparation of emulsions.
Place 1.0 g of the powdered herbal drug (125-250) in a 1000 mL round-bottomed flask with a ground-glass stopper, add 8.0 mL of ethanol (96 per cent) and close the flask. Disperse the suspension over the inner surface of the flask by shaking, taking care not to wet the stopper. Open the flask and add as a single portion 72.0 mL of water. Stopper the flask and shake vigorously for 3 min. Allow to stand for 24 h and shake vigorously again for 3 min. Eliminate air bubbles by applying vacuum above the mucilage for 5 min. Transfer the mucilage to a 50 mL cylinder. Dip in the mucilage a piece of glass tubing 200 mm long and 6.0 mm in internal diameter and graduated at 20 mm and 120 mm from the lower end; the tubing must not be rinsed with surface-active substances. When the mucilage has reached the upper mark, close the tube with a finger. Withdraw the closed tube, remove the finger and measure with a stopwatch the time needed for the meniscus to reach the lower graduation. Carry out this operation 4 times and determine the average value of the last 3 determinations.
Total ash: Maximum 4.0 per cent.
TAMC: acceptance criterion 10000 CFU/g.
TYMC: acceptance criterion 100 CFU/g.
Absence of Escherichia coli.
Absence of Salmonella.
The label states whether or not the contents are suitable for preparing emulsions.
Specifications of Tragacanth FCC Food Grade:
Gum Tragacanth; Tragacanth Gum
INS: 413 CAS: [9000-65-1]
Tragacanth is a dried, gummy exudation obtained from the stems and branches of Astragalus gummifer Labillardiere, or other Asiatic species of Astragalus (Fam. Leguminosae). It consists mainly of high-molecular-weight polysaccharides (arabinogalactans and acidic polysaccharides) that, on hydrolysis, yield galacturonic acid, galactose, arabinose, xylose, and fucose; small amounts of rhammnose and of glucose (derived from traces of starch and/or cellulose) may also be present. Unground Tragacanth occurs as flattened, lamellated, frequently curved fragments or straight or spirally twisted linear pieces from 0.5 to 2.5 mm in thickness. It is white to weak yellow (although some pieces may have a red tinge) and translucent, with a horny texture and a short fracture. It is easier to pulverize if heated to 50C. Powdered Tragacanth is white to yellow-white or pink brown.
Function: Stabilizer; thickener; emulsifier.
A. Microscopic examination of an unground sample in water mounts reveals numerous angular fragments with circular or irregular lamellae, and starch grains up to 25 _m in diameter. There should be very few or no fragments of lignified vegetable tissue.
B. Add iodinated zinc chloride solution to a representative sample. Cellular membranes turn violet.
C. One gram of sample in 50 mL of water swells to form a smooth, stiff, opalescent mucilage free from cellular fragments. The same amount of sample does not swell in 60% (w/v) aqueous ethanol.
Ash (Total): Not more than 3.0%.
Ash (Acid-Insoluble): Not more than 0.5%.
Karaya Gum: Passes test.
Lead: Not more than 2 mg/kg.
Viscosity of a 1% Solution: Not less than 250 centipoises.
For Original Monographs of IP Indian Pharmacopoeia BP British Pharmacopoeia USP US Pharmacopoeia FCC Food Grade product, please check with the respective web-pages or books.
We also manufacture and supply as under:
Carboxymethyl Hydroxypropyl Guar or CMHPG
Gum Acacia or Gum Arabic
Hydroxypropyl Guar Gum
Locust Bean Gum
Ambernath Mumbai, Ankleshwar Gujarat, India
TEL: (OFFICE) +912223770100, +912223726950
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Last 12 November, 2023
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Tragacanth or Gum Tragacanth SDS, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet 22-Oct-20
Section 1: Chemical Product and Company Identification
Product Name & Other Names: Tragacanth or Gum Tragacanth.
CAS Number: 9000-65-1
EINECS EC Code: 232-552-5
Relevant uses and uses advised against (if any): Industrial Manufacturing.
Suppliers: As per letterhead.
Section 2: Hazards Identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Hazard Class and Category Code(s), Regulation (EC) No 1272/2008 (CLP)
Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
This substance is not classified as dangerous according to Directive 67/548/EEC.
Labeling Regulation EC 1272/2008 (CLP) & GHS
GHS Label Elements
Signal Word: None
Hazards not otherwise classified (HNOC):
May causes mild skin irritation.
May causes mild eye irritation.
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P262: Do not get in eyes, on skin, or on clothing.
P281: Use personal protective equipment as required.
P302+P352 - IF ON SKIN: Wash with plenty of soap and water.
P303+P361+P353 - IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
P304 + P340 - IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+313: If eye irritation persists get medical advice/attention.
Section 3: Composition and Information on Ingredients
Product Name & Other Names: Tragacanth or Gum Tragacanth.
CAS Number: 9000-65-1
EINECS EC Code: 232-552-5
Section 4: First Aid Measures
Always seek medical advice after the first aid treatment.
Skin: Rinse with water. Soap may be used. Seek Medical Aid.
Eyes: Wash eyes with plenty of water for at least 15 minutes, lifting lids occasionally. Seek Medical Aid.
Inhalation: Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Ingestion: If swallowed, induce vomiting immediately after giving two glasses of water. Never give anything by mouth to an unconscious person.
Section 5: Fire and Explosion Data
Flammability of the Product: Non-flammable. It can burn at high temperature or as dust air mixture.
Products of Combustion: Fumes and Oxides of Carbon.
Fire Fighting Media and Instructions: Use water spray, alcohol-resistant foam, dry chemical, or carbon dioxide. Wear self-contained breathing apparatus for firefighting if necessary.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes.
Section 6: Accidental Release Measures
Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Ensure adequate ventilation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment Cleanup procedures and Storage:
Small Spill: Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to legal requirements.
Large Spill: Contain spilled material. Do not inhale vapors, mist, or gas. Avoid dust formation. Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and allow as per law.
Section 7: Handling and Storage
Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Do not leave the material container open. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like oxidizing agents.
Section 8: Exposure Controls/Personal Protection
Exposure Guideline: Not established.
Engineering Controls: Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits. If user operations generate dust, fume, or mist, use ventilation to keep exposure to airborne contaminants below the exposure limit.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Dust deposits on floors and other surfaces may pick up moisture and cause the surfaces to become slippery and present safety hazards. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.
Section 9: Physical and Chemical Properties
Physical state and appearance: Off-white to light-yellow powder.
Odor: Not available.
Odor threshold: Not available.
pH (5% soln/water): Not available.
Relative density: Not available.
Melting point/freezing point: Not available.
Initial boiling point and boiling range: Not available.
Flash point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility: Slightly soluble in water. Insoluble in alcohol.
Viscosity: Not available.
Section 10: Stability and Reactivity Data
Stability: It is stable in room temperature in closed containers under normal storage & handling.
Conditions of instability: Incompatible materials, Moisture
Incompatibility with various substances: Avoid high temperatures, sparks, open flame, and moisture. Avoid contact with strong oxidizing agents.
Polymerization: Will not occur.
Section 11: Toxicological Information
LD50 Oral – Rat: 10200 mg/kg
LD50 Oral – Mouse: 10000 mg/kg
LD50 Oral, Rabbit: 7200 mg/kg.
Carcinogenic Effects: Not a reported carcinogen by IARC, NTP, ACGIH, OSHA.
Mutagenic Effects: Not available.
Developmental Toxicity: Not available.
Reproductive Effects: No information available.
Section 12: Ecological Information
Toxicity to fish: No information available.
Persistence and Degradability: Degradable.
Mobility: Likely to be mobile.
Bioaccumulation/ Accumulation: Not likely to accumulate.
Section 13: Disposal Considerations
Waste Disposal: Waste must be disposed of in accordance with federal, state, and local environmental control regulations.
Section 14: Transport Information
DOT USA, TDG Canada & ADR/RID Europe: Not dangerous goods
IMDG: Not dangerous goods
IATA: Not dangerous goods.
Section 15: Other Regulatory Information
USA Regulations:Section 16 - Additional Information
SARA Section 302 Extremely Hazardous Substances: None of the chemicals in this product have a TPQ.
Section 313: No chemicals are reportable under Section 313.
OSHA: None of the chemicals in this product are considered highly hazardous by OSHA.
California Prop 65: California No Significant Risk Level: None of the chemicals in this product are listed.
Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.