Sodium Polystyrene Sulfonate USP BP Ph Eur Manufacturers, with SDS GHS MSDS Sheet

Supplier, Manufacturer, Exporter of Sodium Polystyrene Sulfonate, Muby Chemicals of Mubychem Group, established in 1976, is the original manufacturers of Specialty Chemicals, Pharmaceutical Excipient, Fragrance Food & Flavor chemicals, Reagent Grade Chemicals, Shale Gas Fracturing Chemicals in India. Mubychem Group has several manufacturing facilities spread across Western India and world wide contacts and toll manufacturers. We are exporting globally to countries like USA, Canada, Europe, UAE, South Africa, Tanzania, Kenya, Egypt, Nigeria, Cameroon, Uganda, Turkey, Mexico, Brazil, Chile, Argentina, Dubai, Korea, Vietnam, Thailand, Malaysia, Indonesia, Australia, China, Germany, France, Italy, Portugal etc.

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Sodium Polystyrene Sulfonate: CAS Number: 25704-18-1 also reported are 9003-59-2 & 9080-79-9, EINECS EC Number: yyyyy, Molecular Formula: [-CH2CH(C6H4SO3Na)-]n, Molecular Weight: yy, HS Code ---**

Specifications, Safety Data Sheet, Manufacturing process details, Wholesale retail buy sell prices, Uses etc available on line in these pages for Sodium Polystyrene Sulfonate.

Polystyrene sulfonates are polymers derived from polystyrene by the addition of sulfonate functional groups. They are widely used as ion-exchange resins to remove ions such as potassium, calcium, and sodium from solutions in technical or medical applications.

Sodium polystyrene sulfonate is a cation-exchange resin. Sodium polystyrene sulfonate is also used to treat hyperkalemia (increased amounts of potassium in the body). Sodium polystyrene sulfonate is in a class of medications called potassium-removing agents. It works by removing excess potassium from the body.

General Specification for Sodium Polystyrene Sulfonate
Potassium Exchange Capacity (Anhydrous Basis): 110 mg/g to 135 mg/g
Sodium Content (Dried Basis): 9.4% to 11.5 %
water Determination: 10.0 %
Ammonium salts: To pass the test.
Identification: To pass the test.
Residual Solvent: To pass the test.

Sodium Polystyrene Sulfonate Suspension is a suspension of Sodium Polystyrene Sulfonate in an aqueous vehicle that may contain suitable suspending or stabilizing agents. It exchanges not less than 110 mg and not more than 135 mg of potassium for each g of the labeled amount of sodium polystyrene sulfonate.

Packaging and storage: Preserve in well-closed containers, protected from freezing and from excessive heat.

Microbial limits: Its total aerobic microbial count does not exceed 100 cfu per mL, its total combined molds and yeasts count does not exceed 100 cfu per mL, and it meets the requirements of the test for absence of Pseudomonas aeruginosa.
Sodium content: Not less than 9.4% and not more than 11.5%.
Potassium exchange capacity: (Anhydrous Basis) 110 mg/g to 135 mg/g.

Sodium Polystyrene Sulphonate BP Grade
Ph Eur
Action and use: Used in the treatment of hyperkalaemia.

DEFINITION
Polystyrene sulphonate resin prepared in the sodium form.
Exchange capacity: 2.8 mmol to 3.4 mmol of potassium per gram (dried substance).
Content: 9.4 per cent to 11.0 per cent of Na (dried substance).

CHARACTERS
Appearance: Almost white or light brown powder.
Solubility: Practically insoluble in water, in alcohol and in methylene chloride.

IDENTIFICATION
A. Infrared absorption spectrophotometry.
B. Suspend 0.1 g in water, add 2 ml of a 150 g/l solution of potassium carbonate, and heat to boiling. Allow to cool and filter. To the filtrate add 4 ml of potassium pyroantimonate solution and heat to boiling. Allow to cool in iced water and if necessary rub the inside of the test-tube with a glass rod. A dense white precipitate is formed.

TESTS
Styrene: To pass the test by liquid chromatography (1 ppm).
Calcium: Maximum 0.10 per cent.
Potassium: Maximum 0.10 per cent.
Heavy metals: Maximum 10 ppm.
Loss on drying: Maximum 7.0 per cent, determined on 1.000 g by drying in an oven at 105C.
Microbial contamination: Not more than 100 enterobacteria and certain other gram-negative bacteria per gram.
Sodium: To pass the test by atomic emission spectrometry
Exchange capacity: To pass the test by atomic emission spectrometry.

For Original Monographs of IP Indian Pharmacopoeia BP British Pharmacopoeia USP US Pharmacopoeia FCC Food Grade product, please check with the respective web-pages or books.

MUBY CHEMICALS
Ambernath Mumbai, Ankleshwar Gujarat, India
TEL: (OFFICE) 91-22-23770100, 23726950
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Sodium Polystyrene Sulfonate or Sodium Polystyrene Sulphonate SDS, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet

Product Name & Other Names: Sodium Polystyrene Sulfonate or Sodium Polystyrene Sulphonate.
CAS #: 25704-18-1 also reported are 9003-59-2 & 9080-79-9
Relevant uses and uses advised against (if any): Industrial use only.
Supplier: As per letterhead.

GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008

Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
This substance is not classified as dangerous according to Directive 67/548/EEC.

Hazards not otherwise classified (HNOC):
The toxicological properties of this material have not been fully investigated.
May causes mild skin irritation.
May causes mild eye irritation.
May cause irritation of digestive tract.
May cause irritation of respiratory tract.

Precautionary statements:
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P262: Do not get in eyes, on skin, or on clothing.
P281: Use personal protective equipment as required.
P302+P352 - IF ON SKIN: Wash with plenty of soap and water.
P304 + P340 - IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+313: If eye irritation persists get medical advice/attention.

Product Name & Other Names: Sodium Polystyrene Sulfonate or Sodium Polystyrene Sulphonate.
CAS #: 25704-18-1 also reported are 9003-59-2 & 9080-79-9.

Skin: Wash exposed area with soap and water.
Eyes: Wash eyes with plenty of water for at least 15 minutes, lifting lids occasionally. Seek Medical Aid.
Inhalation: Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Ingestion: If swallowed, induce vomiting immediately after giving two glasses of water. Never give anything by mouth to an unconscious person.

Flammability of the Product: Non-flammable.
Products of Combustion: Sodium oxide with oxides of sulfur, carbon, and fumes.
Extinguisher Media: Use media suitable to extinguish surrounding fire. Use alcohol-resistant foam, dry chemical, or carbon dioxide.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes. Fire-extinguishing work is done from the windward and the suitable fire-extinguishing method according to the surrounding situation is used. Uninvolved persons should evacuate to a safe place.

Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil or water sources.
Methods and materials used for containment Cleanup procedures and Storage:
Small Spill: Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to legal requirements.
Large Spill: Contain spilled material. Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and allow to evacuate through the sanitary system.

Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Do not leave the material container open. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like incompatibles, oxidizing agents, acids. Keep in original containers and avoid contact with moisture.

Exposure Guidelines: Not established.
Engineering Controls: Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits. If user operations generate dust, fume, or mist, use ventilation to keep exposure to airborne contaminants below the exposure limit.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Dust deposits on floors and other surfaces may pick up moisture and cause the surfaces to become slippery and present safety hazards. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.

Physical state and appearance: Cream to light brown solid.
Odor: Not available.
Odor threshold: Not available.
pH: Not available.
Relative density: 0.8
Melting Point: 450C.
Initial boiling point and boiling range: Not available.
Flash point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility: Soluble in water.
Viscosity: Not available.

Stability: Sodium Polystyrene Sulfonate is stable.
Conditions of Instability: Incompatible materials
Incompatibility with various substances: Oxidizing agents, Heat and Dust formation.
Corrosivity: Non-corrosive in presence of glass.
Hazardous Decomposition Products: Sodium oxide with oxides of sulfur, carbon and fumes.
Polymerization: Will not occur.

Toxicity to Animals: LD50 (Oral) Rat >8000 mg/kg. LC50 (Inhalation) Rat – 4 h – 2,600 mg/m3.
Carcinogenicity: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC, NTP & ACGIH.
Mutagenic Effects: Not available.
Developmental Toxicity: Not available.
Reproductive Effects: No information available.

Ecotoxicity: The product is not expected to be harmful to marine life.
Persistence and Degradability: Soluble in water. Persistence is unlikely as per information available.
Mobility: Likely to be mobile due to water solubility.
Bioaccumulation/ Accumulation: No information available.
Results of PBT and vPvB assessment: No data available for assessment.
Products of Biodegradation: Possibly hazardous short-term degradation products are not likely. However, long term degradation products may arise.

Waste Disposal: Waste must be disposed of in accordance with federal, state, and local environmental control regulations.

DOT USA, TDG Canada & ADR/RID Europe: Not dangerous goods
IMDG/IMO: Not dangerous goods
IATA: Not dangerous goods.

USA Regulations:
SARA 302: No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302.
SARA 313: This material does not contain any chemical components with known CAS numbers that exceed the threshold (De Minimis) reporting levels established by SARA Title III, Section 313.
California Prop. 65 Components: This product does not contain any chemicals known to State of California to cause cancer, birth defects, or any other reproductive harm.

Disclaimer:
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Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
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