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Mubychem Group, established in 1976, is the pioneer manufacturer of Zinc Chloride, Ammonium Chloride, Calcium Chloride, Potassium Chloride, Sodium Acetate, Sodium Thiosulphate or Sodium Thiosulfate Potassium bromide and various Pharmaceutical Chemicals in India.  Mubychem Group has manufacturing facilities spread across Gujarat and Maharashtra (Western India). 


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Potassium Bromide Pure

Is offered as crystals. Only high quality product is offered.

Pota. Bromide MSDS

Potassium bromide (KBr) is a salt, widely used as an anticonvulsant and a sedative in the late 19th and early 20th centuries. KBr's action is due to the bromide ion (sodium bromide is equally effective). It is presently used as a veterinary drug, as an antiepileptic medication for dogs and cats. KBr is a white crystalline powder, soluble in water. In a dilute aqueous solution, it tastes sweet, at higher concentration it tastes bitter and when more concentrated, KBr tastes salty to humans (these effects are due mainly to potassium ion; sodium bromide merely tastes salty at all concentrations). In high concentration KBr strongly irritates the gastric mucous membrane, leading to nausea and sometimes vomiting (again this effect is typical of all soluble potassium salts).

Potassium Bromide BP USP ACS AR

We offer Potassium Bromide BP, USP and EP from our world class FDA approved, ISO-9001-2008 Certified facility, Anmol Chemicals

 

Potassium Bromide Chemical Properties

KBr
Identifiers
CAS number [7758-02-3]
PubChem 253877
RTECS number TS7650000
Properties
Molecular formula KBr
Molar mass 119.002 g/mol
Appearance white solid
Density 2.75 g/cm3
Melting point 734 °C, 1007 K, 1353 °F
Boiling point 1435 °C, 1708 K, 2615 °F
Solubility in water 53.5 g/100 ml (0 °C)
102 g/100 mL (100 °C)
Solubility in glycerol 21.7 g/100 mL
Solubility in ethanol 4.76 g/100 mL (80 °C)
Structure
Crystal structure Sodium chloride
Coordination
geometry
octahedral
Dipole moment 10.41 D (gas)
Hazards
EU Index Not listed
Related compounds
Other anions Potassium fluoride
Potassium chloride
Potassium iodide
Other cations Lithium bromide
Sodium bromide
Rubidium bromide
Caesium bromide

It is a typical ionic salt which is fully dissociated and near pH 7 in aqueous solution. It serves as a source of bromide ions- this reaction is important for the manufacture of silver bromide for photographic film:

KBr(aq) + AgNO3(aq) → AgBr(s) + KNO3(aq)

Aqueous bromide Br- will also form complexes when reacted with some metal halides such as copper(II) bromide:

2 KBr(aq) + CuBr2(aq) → K2[CuBr4](aq)

It is used extensively in photography. It is also sometimes used as a bromide source in organic synthesis, since it is less hygroscopic than sodium bromide. In the laboratory KBr is commonly used in infrared spectroscopy. The sample to be tested is crushed up with a large excess of KBr and then the mixture is crushed to form a tablet which is inserted into the spectrophotometer.

Preparation

A traditional method for the manufacture of KBr is the reaction of potassium carbonate with a bromide of iron, Fe3Br8, made by treating scrap iron under water with excess bromine:

4 K2CO3 + Fe3Br8 → 8 KBr + Fe3O4 + 4 CO2

Medical and Veterinary

The anticonvulsant properties of KBr were first noted by Sir Charles Locock at a meeting of the Royal Medical and Chirurgical Society in 1857. Bromide can be regarded as the first effective medication for epilepsy. At the time, it was commonly thought that epilepsy was caused by masturbation. Locock noted that bromide calmed sexual excitement and thought this was responsible for his success in treating seizures. There would not be a better drug for epilepsy until phenobarbital in 1912. It was often said the British Army laced the soldiers' tea with bromide to quell sexual arousal, however because doing so would also diminish alertness in battle it is likely to be an urban legend and similar stories were also told about a number of substances.

Potassium bromide is used to treat epilepsy in dogs, either as first-line treatment or in addition to phenobarbital when the seizures are not adequately controlled with phenobarbital alone. Use of bromide in cats is limited because it carries a substantial risk of causing lung inflammation (pneumonitis) in this species.

KBr is not approved by the US Food and Drug Administration (FDA) for use in humans to control seizures. In Germany KBr continues to be approved for use as an antiepileptic drug for humans, particularly children and adolescents. These indications include severe forms of generalized tonic-clonic seizures, early-childhood-related Grand-Mal-seizures, and also severe myoclonic seizures during childhood. Adults who have reacted positively to the drug during childhood/adolescence may continue treatment. KBr is sold under the brand name Dibro-Be mono (RX-only). When used for proper indications it shows promising results. The drug has almost complete bioavailability and an extremely long half-life of 6 weeks. One tablet contains 850 mg of potassium bromide. It is not known to interfere with the absorption or excretion of any other anticonvulsant.

The therapeutic index is very small for bromide. As with other antiepileptics, sometimes even therapeutic doses give rise to intoxication. Often indistinguishable from 'expected' side-effects, these include:

  • Loss of appetite, nausea/emesis, lethargy, propensity to sleep during the daytime, depression, loss of concentration and memory, confusion, headache, and

  • Bromism (central reactions reaching from somnolence to coma, cachexia, exicosis, loss of reflexes or pathologic reflexes, clonic seizures, tremor, ataxia, loss of neural sensitivity, paresis, papillar edema of the eyes, abnormal speech, cerebral edema, delirium, aggressiveness, psychoses)

  • Acne-form dermatitis and other forms of skin disease may also be seen, as well as mucous hypersecretion in the lungs. Asthma and rhinitis may worsen. Rarely, tongue disorder, aphten, bad breath, and obstipation occur.

Optics

KBr is transparent from the near ultraviolet to long wave infrared wavelengths (0.25-25 µm). It has no significant optical absorption lines in its high transmission region. It is used for optical windows and prisms. It must be kept in a dry environment due to high solubility and hygroscopic nature. The refractive index is about 1.55 at 1.0 µm.

In infrared spectroscopy, samples are analyzed by grinding with KBr powder, and pressing into a disc. Alternatively, the samples may be analyzed as a liquid film (neat, as a solution, or in a mull with Nujol) between two polished KBr discs.

More from Potassium Bromide manufacturer at:
MUBY CHEMICALS
S-8, SARIFA MANSION, 2ND FLANK ROAD, CHINCHBUNDER, MUMBAI 400009, INDIA.
TEL: (OFFICE) 91-22-23770100, 23726950, 23774610, 23723564. FAX: 91-22-23728264.

 e-mail: info@mubychem.com

Cell Call to Anmol: +91-9821870100 or Ambrish: +91-9821570100
US and Canadian Customers may call (281) 645 6868.

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Last updated: 24 January, 2010.

 

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