Piperazine Dihydrochloride USP Grade Manufacturers, with SDS GHS MSDS Sheet

Supplier, Manufacturer, Exporter of Piperazine Dihydrochloride, Muby Chemicals of Mubychem Group, established in 1976, is the original manufacturers of Specialty Chemicals, Pharmaceutical Excipient, Fragrance Food & Flavor chemicals, Reagent Grade Chemicals, Shale Gas Fracturing Chemicals in India. Mubychem Group has several manufacturing facilities spread across Western India and world wide contacts and toll manufacturers. We are exporting globally to countries like USA, Canada, Europe, UAE, South Africa, Tanzania, Kenya, Egypt, Nigeria, Cameroon, Uganda, Turkey, Mexico, Brazil, Chile, Argentina, Dubai, Korea, Vietnam, Thailand, Malaysia, Indonesia, Australia, China, Germany, France, Italy, Portugal etc.

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Piperazine Dihydrochloride CAS Number 142-64-3 for anhydrous and 207605-49-0 for hydrate, EINECS EC Number: 205-551-2, Molecular Formula: C4H10N2-2HCl or C4H12Cl2N2, Molecular Weight: 159.06 (anhydrous), HS Code 29335990 or 29334900 or 29335990

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Specifications, Safety Data Sheet, Manufacturing process details, Wholesale retail buy sell prices, Uses etc available on line in these pages for Piperazine Dihydrochloride.

For SDS MSDS Sheet Click
SDS MSDS Sheet of Piperazine Dihydrochloride Manufacturers

Piperazine Dihydrochloride
USP Grade Pure Suppliers
Piperazine Dihydrochloride

Piperazine dihydrochloride appears as white to cream-colored needles or powder. It produces a neuromuscular block leading to flaccid muscle paralysis in susceptible worms, which are then dislodged from the gut and expelled in feces. It is combustible Solid but does not ignite easily.

General Properties and Specifications of Piperazine Dihydrochloride:
Appearance: White to cream-colored needles or powder.
Assay: 99%
Melting point: 318C to 320C literature.
Solubility: Soluble in water.


Piperazine Dihydrochloride USP Grade Specifications:
C4H10N2- 2HCl-x H2O -- 159.06 (anhydrous)
Piperazine dihydrochloride hydrate CAS 142-64-3.
Piperazine Dihydrochloride contains not less than 98.5 percent and not more than 100.5 percent of C4H10N2-2HCl, calculated on the anhydrous basis.

Packaging and storage: Preserve in well-closed containers, and store at room temperature.
Identification:
A: Infrared Absorption
B: In the test for Chromatographic purity, the principal spot in the chromatogram obtained from Test solution 2, observed after spraying with the ninhydrin solutions, corresponds in R F value, color, and size to that in the chromatogram obtained from Standard solution 1.
C: It meets the requirements of the test for Chloride.

pH: between 3.0 and 3.4, in a solution (1 in 20).
Water Determination: not more than 10.0%.
Residue on ignition: not more than 0.1%.
Chromatographic purity: To pass the test.
Assay: Dissolve about 140 mg of Piperazine Dihydrochloride in 4 mL of ethylene glycol using a 150-mL beaker. Add 25 mL of glacial acetic acid containing 1.2 g of mercuric acetate, rinsing the walls of the beaker with a small amount of the glacial acetic acid. Add 0.25 mL of p-naphtholbenzein and titrate with 0.1 N perchloric acid. Perform a blank determination and make any necessary correction. Each mL of 0.1 N perchloric acid is equivalent to 7.953 mg of C4H10N2- 2HCl.

For Original Monographs of IP Indian Pharmacopoeia BP British Pharmacopoeia USP US Pharmacopoeia FCC Food Grade product, please check with the respective web-pages or books.

We also manufacture and supply as under:

N-Aminoethylpiperazine

1-(3-chlorophenyl)-4-(3-chloropropyl)piperazine hydrochloride

1-(3-Chlorophenyl)piperazine

1-[2-(2-Hydroxyethoxy)ethyl]piperazine

1-(3-Hydroxymethylpyridin-2-yl)-4-methyl-2-phenylpiperazine

N-methylpiperazine

Piperazine Anhydrous & Hydrate

Piperazine Adipate

Piperazine Dihydrochloride

Piperazine Phosphate.

Manufacturers:

MUBY CHEMICALS
Ambernath Mumbai, Ankleshwar Gujarat, India
TEL: (OFFICE) +912223770100, +912223726950
Current Date Time in India GMT+5:30

e-mail: info@mubychem.com

USA, Canada, Mexico and other American
neighbouring buyers may
e-mail: us@mubychem.com
Call toll-free 1-844-682-9243 (1-844-MUBYCHEM)

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Last 27 August, 2022

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Piperazine Dihydrochloride SDS, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet
25-Mar-22

1. Product Identification

Product Name & Other Names: Piperazine Dihydrochloride.
CAS No.: 142-64-3 for anhydrous and 207605-49-0 for hydrate
EINECS EC Number: 205-551-2
Molecular Weight: 159.06 (anhydrous)
Chemical Formula: C4H10N2-2HCl or C4H12Cl2N2
Relevant uses and uses advised against (if any): Industrial Manufacturing.
Suppliers: As per letterhead.

2. Hazards Identification

GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008

Skin corrosion/irritation Category 2, H315
Serious eye damage/eye irritation Category 2A, H319
Specific target organ toxicity, single exposure; Respiratory tract irritation Category 3, H335

Labeling according to Regulation (EC) No 1272/2008

GHS Label Elements
Irritant
Irritant

Signal Words: Warning

Hazard statements:
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.

Precautionary statements:
P262: Do not get in eyes, on skin, or on clothing.
P264: Wash skin thoroughly after handling.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P270: Do not eat, drink or smoke when using this product.
P273: Avoid release to the environment.
P330: Rinse mouth.
P362: Take off contaminated clothing and wash before reuse.
P301+312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P332+313: If skin irritation occurs: Get medical advice/attention.
P302+ P352 - IF ON SKIN: Wash with plenty of soap and water.
P305+ P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P332+313: If skin irritation occurs: Get medical advice/attention.
P337+P313 If eye irritation persists: Get medical advice/ attention.
P501: Dispose of contents/container to authorized agents only.

Classification according to EU Directives 67/548/EEC or 1999/45/EC:
Hazard Symbol:
Xi Irritant
Risk Phrase:
R36/37/38: Irritating to eyes, respiratory system & skin.

3. Composition/Information on Ingredients

Product Name & Other Names: Piperazine Dihydrochloride.
CAS No.: 142-64-3 for anhydrous and 207605-49-0 for hydrate
EINECS EC Number: 205-551-2

4. First Aid Measures

Inhalation: Remove to fresh air. Give oxygen if breathing is difficult; give artificial respiration if breathing has stopped. Keep person warm and quiet; get medical attention.
Ingestion: Induce vomiting immediately as directed by medical personnel. Never give anything by mouth to an unconscious person.
Skin Contact: Immediately flush skin with plenty of soap and water for at least 15 minutes. Remove contaminated clothing and shoes. Wash clothing before reuse. Thoroughly clean shoes before reuse. Get medical attention if irritation develops.
Eye Contact: Immediately flush eyes with plenty of water for at least 15 minutes, lifting upper and lower eyelids occasionally. Get medical attention.
Note to physicians: Treat symptomatically.

5. Fire Fighting Measures

Fire: Can be a fire hazard at elevated temperatures.
Fire Extinguishing Media: Use water spray, alcohol-resistant foam, dry chemical, or carbon dioxide.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes. Fire-extinguishing work is done from the windward and the suitable fire-extinguishing method according to the surrounding situation is used. Uninvolved persons should evacuate to a safe place. In case of fire in the surroundings: Remove movable containers if safe to do so.

6. Accidental Release Measures

Personal precautions, protective equipment, and emergency procedures: Ventilate area of leak or spill. Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment cleanup procedures and Storage: Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g., sand, earth, diatomaceous earth, vermiculite). Vacuum or sweep-up and remove to an approved disposal container.

7. Handling and Storage

Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like strong oxidizing agents and strong bases.

8. Exposure Controls/Personal Protection

Airborne Exposure Limits: Exposure limits not established by any known regulatory bodies.
Ventilation System: In general, dilution ventilation is a satisfactory health hazard control. However, if conditions of use create discomfort to the worker, use a local exhaust system.
Personal Respirators (NIOSH Approved): Not expected to require personal respirator usage. For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator (NIOSH type N95 or better filters) may be worn. If oil particles are present, use a NIOSH type R or P filter. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full-face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Dust deposits on floors and other surfaces may pick up moisture and cause the surfaces to become slippery and present safety hazards. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.

9. Physical and Chemical Properties

Appearance: White to cream-colored needles or powder.
Odor: Not available.
Odor threshold: Not available.
pH: Not available.
Relative density: Not available.
Boiling Point: Not available.
Melting Point: 318C to 320C literature.
Flash point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility: Soluble in water.
Viscosity: Not available.
Molecular Weight: 159.06 (anhydrous)
Chemical Formula: C4H10N2-2HCl or C4H12Cl2N2

10. Stability and Reactivity

Stability: Stable under ordinary conditions of use and storage.
Hazardous Decomposition Products: May produce oxides of nitrogen and carbon, hydrogen chloride gas, toxic fumes when heated to decomposition.
Hazardous Polymerization: Will not occur.
Incompatibilities: Strong oxidizing agents and strong bases.
Conditions to Avoid: Sunlight, moisture, heat, flame, ignition source, dusting and incompatibles.

11. Toxicological Information

Carcinogenic Effects: Not a reported carcinogen by IARC, NTP, ACGIH, OSHA.
Mutagenic Effects: No information available
Reproductive Effects: No information available.
No further acute toxicity information is available for this product.

12. Ecological Information

Toxicity to fish: No information available.
Persistence and Degradability
: No information available.
Mobility: No information available.
Results of PBT and vPvB assessment: No data available for assessment.

13. Disposal Considerations

Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. Processing use or contamination of this product may change the waste management options. Dispose of container and unused in accordance with law.

14. Transport Information

DOT USA, TDG Canada & ADR/RID Europe: Not regulated.
IMDG/IMO & IATA/ICAO: Not regulated.

15. Regulatory Information

USA:
SARA 313
: Not applicable
SARA 311/312 Hazardous Categorization: Acute Health Hazard.
California Proposition 65: This product does not contain any Proposition 65 chemicals

16. Other Information

Disclaimer:
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Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
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