4-Chloro-meta-cresol or p-Chlorocresol or PCMC or 4-Chloro-3-methylphenol BP Ph Eur USP NF Grade Manufacturers, with SDS GHS MSDS Sheet |
Supplier, Manufacturer, Exporter of p-Chlorocresol or PCMC or 4-Chloro-3-methylphenol, Muby Chemicals of Mubychem Group, established in 1976, is the original manufacturers of Specialty Chemicals, Pharmaceutical Excipient, Fragrance Food & Flavor chemicals, Reagent Grade Chemicals, Shale Gas Fracturing Chemicals in India. Mubychem Group has several manufacturing facilities spread across Western India and world wide contacts and toll manufacturers. We are exporting globally to countries like USA, Canada, Europe, UAE, South Africa, Tanzania, Kenya, Egypt, Nigeria, Cameroon, Uganda, Turkey, Mexico, Brazil, Chile, Argentina, Dubai, Korea, Vietnam, Thailand, Malaysia, Indonesia, Australia, China, Germany, France, Italy, Portugal etc. The products are offered as per required specifications and in correct shape and size in mm or meshs or microns as specified by the buyer. The participating units have one or more accreditations like FDA - cGMP and GLP approval, ISO-9001 Certified, "REACH" Registered, ISO-14001, ISO/IEC 17025, ISO-22000, FSSC 22000, ISO 45001, Kosher Certified, Halal Certified, HACCP, FSSAI. We offer Commercial Pure & IP BP EP Ph Eur USP NF JP FCC Food Grade Analytical Reagent Grades of Chemicals |
| Bookmark this Web Site -- or -- Email This Page Info to a Colleague or Yourself |
Search our website here:
--------- 
4-Chloro-meta-cresol or p-Chlorocresol or PCMC or 4-Chloro-3-methylphenol: CAS Number: 59-50-7, EINECS EC Number: 200-431-6, Molecular Formula: C7H7ClO or ClC6H3(CH3)OH, Molecular Weight: 142.58, HS Code ---**
How big is your requirement or how small
We serve it all.
Specifications, Safety Data Sheet, Manufacturing process details, Wholesale retail buy sell prices, Uses etc available on line in these pages for p-Chlorocresol or PCMC or 4-Chloro-3-methylphenol.
For SDS MSDS Sheet Click
SDS MSDS Sheet of p-Chlorocresol or PCMC or 4-Chloro-3-methylphenol Manufacturers
p-Chlorocresol
4-Chloro-meta-cresol or PCMC or 4-Chloro-3-methylphenol Pure Suppliers
4-Chloro-meta-cresol or p-Chlorocresol is the organic compound with the formula ClC6H4OH. It is a monochlorinated m-cresol. It is a white or colorless solid that is only slightly soluble in water. As a solution in alcohol and in combination with other phenols, it is used as an antiseptic and preservative. It is also a veterinary medicine.
General Properties and Specifications of p-Chlorocresol or 4-Chloro-3-methylphenol:
Appearance: White/pink solid.
Assay: 99% minimum.
Odor: Phenolic
Relative Density: 1.37 @ 20C
Melting point: 64C-67C literature.
Boiling point: 235C literature.
Solubility in water: 3.8 g/l @20C.
Specifications of Chlorocresol USP NF Grade:
C7H7ClO --- 142.58
Phenol, 4-chloro-3-methyl-;
4-Chloro-m-cresol --- [CAS 59-50-7]
DEFINITION
Chlorocresol contains NLT 99.0% and NMT 101.0% of C7H7ClO (4-chloro-3-methylphenol).
IDENTIFICATION
A.
Sample solution: Dissolve 40 mg of Chlorocresol in 10 mL of water.
Analysis: Add 1 drop of ferric chloride TS to the Sample solution.
Acceptance criteria: A blue color develops.
B.
Sample: 50 mg
Analysis: Transfer the Sample to a crucible, add 500 mg of anhydrous sodium carbonate, and mix. Heat the mixture until fused. Cool, add 5 mL of water, and boil. Acidify with 1 mL of nitric acid, filter, and add 1 mL of silver nitrate TS to the filtrate.
Acceptance criteria: A white precipitate is formed.
ASSAY
To pass the test.
Acceptance criteria: 99.0%–101.0%
Melting Range or Temperature: 63C –66C
Limit of Nonvolatile Residue:
Sample: 1.0 g
Analysis: Heat the Sample in a tared crucible on a steam bath until it has evaporated, and dry the residue at 105° for 1 h.
Acceptance criteria: NMT 0.1%
Completeness of Solution:
Sample: 1 g
Analysis: Transfer the Sample to a test tube, add 0.4 mL of alcohol, and shake.
Acceptance criteria: The solution is complete.
Packaging and Storage: Preserve in tight, light-resistant containers.
Specifications of Chlorocresol BP Ph Eur Grade:
C7H7ClO --- 142.6 --- CAS 59-50-7
Action and use: Antiseptic; antimicrobial preservative.
DEFINITION
4-Chloro-3-methylphenol.
Content: 98.0 per cent to 101.0 per cent.
CHARACTERS
Appearance: White or almost white, crystalline powder or compacted crystalline masses supplied as pellets or colourless or white crystals.
Solubility: Slightly soluble in water, very soluble in ethanol (96 per cent), freely soluble in fatty oils. It dissolves in solutions of alkali hydroxides.
IDENTIFICATION
A. Melting point: 64C to 67C.
B. To 0.1 g add 0.2 mL of benzoyl chloride and 0.5 mL of dilute sodium hydroxide solution. Shake vigorously until a white, crystalline precipitate is formed. Add 5 mL of water and filter. The precipitate, recrystallised from 5 mL of methanol and dried at 70C, melts at 85C to 88C.
C. To 5 mL of solution S (see Tests) add 0.1 mL of ferric chloride solution. A bluish colour is produced.
TESTS
Solution S: To 3.0 g, finely powdered, add 60 mL of carbon dioxide-free water, shake for 2 min and filter.
Appearance of solution: The solution is clear and not more intensely coloured than reference solution.
Dissolve 1.25 g in ethanol (96 per cent) and dilute to 25 mL with the same solvent.
Acidity: To 10 mL of solution S add 0.1 mL of methyl red solution. The solution is orange or red. Not more than 0.2 mL of 0.01 M sodium hydroxide is required to produce a pure yellow colour.
Related substances: To pass the test by gas chromatography.
Limits:
— unspecified impurities: for each impurity, maximum 0.10 per cent;
— total: maximum 1 per cent;
— disregard limit: the area of the principal peak in the chromatogram obtained with the reference solution (0.05 per cent).
Non-volatile matter: Maximum 0.1 per cent.
Evaporate 2.0 g to dryness on a water-bath and dry the residue at 100-105C. The residue weighs not more than 2 mg.
ASSAY
In a ground-glass-stoppered flask, dissolve 70.0 mg in 30 mL of glacial acetic acid. Add 25.0 mL of0.0167 M potassium bromate, 20 mL of a 150 g/L solution of potassium bromide and 10 mL of hydrochloric acid. Allow to stand protected from light for 15 min. Add 1 g of potassium iodide and 100 mL of water. Titrate with 0.1 M sodium thiosulfate, shaking vigorously and using 1 mL of starch solution, added towards the end of the titration, as indicator. Carry out a blank titration.
1 mL of 0.0167 M potassium bromate is equivalent to 3.565 mg of C7H7ClO.
Protected from light.
For Original Monographs of IP Indian Pharmacopoeia BP British Pharmacopoeia USP US Pharmacopoeia FCC Food Grade product, please check with the respective web-pages or books.
We also manufacture and supply as under:
Manufacturers:
MUBY CHEMICALS
Ambernath Mumbai, Ankleshwar Gujarat, India
TEL: (OFFICE) +912223770100, +912223726950
Current Date Time in India GMT+5:30
e-mail: info@mubychem.com
USA, Canada, Mexico and other American
neighbouring buyers may
e-mail: us@mubychem.com
Call toll-free 1-877-682-9243 (1-877-MUBYCHEM)
Copyright and Usual Disclaimer is Applicable.
Last
4 October, 2023
Exporters to USA Canada UAE Europe South Africa Tanzania Kenya Uganda Egypt Nigeria Turkey Mexico Brazil Argentina Chile Dubai etc.
Global or International Suppliers, Exporters, Importers, Manufacturers
I shall pass through this world, but once. If therefore, there is any good that I can do, or if there is any favor that I can show to a fellow human being, let me do it now. Let me not defer or neglect it. For I shall not tread this way again
p-Chlorocresol or PCMC or 4-Chloro-3-methylphenol SDS Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet 11-Nov-20
Section 1. Product Information
Product Name & Other Names: 4-Chloro-meta-cresol or p-Chlorocresol or PCMC or 4-Chloro-3-methylphenol.
CAS No.: 59-50-7
EINECS EC Number: 200-431-6
Chemical Formula: C7H7ClO or ClC6H3(CH3)OH
Molecular Weight: 142.58
Relevant uses and uses advised against (if any): Industrial Manufacturing.
Suppliers: As per letterhead.
Section 2: Hazards Identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008
Acute toxicity, oral Category 4, H302
Acute toxicity, Dermal Category 4, H312
Skin sensitization, Sub-category 1B, H317
Serious eye damage Category 1, H318
Short-term (acute) aquatic hazard Category 1, H400
Labeling according GHS & Regulation (EC) No 1272/2008
| GHS Label Elements  Aquatic Toxicity |
GHS Label Elements |
Signal Words: Danger
Hazard statements:
H302 + H312 Harmful if swallowed or in contact with skin.
H317 May cause an allergic skin reaction.
H318 Causes serious eye damage.
H400 Very toxic to aquatic life.
Precautionary statements:
P202: Do not handle until all safety precautions have been read and understood.
P260: Do not breathe dust/fume/gas/mist/vapors/spray.
P264: Wash … thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P273: Avoid release to the environment.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P284: Wear respiratory protection.
P301+310: IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P304+340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P308+313: IF exposed or concerned: Get medical advice/attention.
P391: Collect spillage.
P405: Store locked up.
P403+233: Store in a well-ventilated place. Keep container tightly closed.
P501: Dispose of contents/container in accordance with local/regional/national/international regulation.
Classification according to EU Directives 67/548/EEC or 1999/45/EC:
Hazard Symbols:
C Corrosive
Xn Harmful
N Dangerous for the environment
Risk Phrases:
R21/22 Harmful in contact with skin and if swallowed.
R41 Risk of serious damage to eyes.
R43 May cause sensitization by skin contact.
R50 Very toxic to aquatic organisms
Section 3: Composition and Information on Ingredients
Product Name & Other Names: p-Chlorocresol or PCMC or 4-Chloro-3-methylphenol.
CAS No.: 59-50-7
EINECS EC Number: 200-431-6
Section 4. First Aid & Procedure
Always get medical attention after the first aid is over.
Ingestion: Never give anything by mouth to an unconscious person. Get medical attention.
Skin: Immediately flush skin with plenty of water for at least 15 minutes. Remove and wash contaminated clothing and shoes before reuse. Get medical attention if irritation develops.
Eyes: Immediately flush eyes with plenty of water for 15 minutes, occasionally lifting upper and lower eyelids. Hold eyelids apart during irrigation. Get medical attention.
Inhalation: Remove person to fresh air. If breathing is difficult, give oxygen. If not breathing administer artificial respiration. Get medical attention.
Section 5. Fire Fighting Measures
Flash Point: N/A
Fire/Explosion: Not considered to be a fire and explosion hazard.
Extinguishing Medium: Water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture: Fumes may evolve along with carbon oxides and hydrogen chloride.
Fire Fighting Instructions: Use suitable protective equipment for surrounding fire.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes. Fire-extinguishing work is done from the windward and the suitable fire-extinguishing method according to the surrounding situation is used. Uninvolved persons should evacuate to a safe place.
Section 6. Spills and Disposals
Personal precautions, protective equipment and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Ensure adequate ventilation. Don't touch or walk through this product. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil or water sources.
Methods and materials used for containment Cleanup procedures and Storage: Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g. sand, earth, diatomaceous earth, vermiculite). Vacuum or sweep-up and remove to an approved disposal container.
Section 7. Handling and Storage
Harmful hazardous material. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Avoid exposure.
Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. Wash thoroughly after handling. Do not drink, eat or smoke while handling. Avoid contact with skin, eyes and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Avoid prolonged or repeated exposure. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cool, dry and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Do not leave the material container open. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like oxidizing agents.
Section 8. Exposure Controls & Personal Protection
Exposure Limits: Contains no components with established occupational exposure limits.
Engineering Controls: Use adequate exhaust ventilation to keep airborne concentrations below the allowable exposure limit.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Dust deposits on floors and other surfaces may pick up moisture and cause the surfaces to become slippery and present safety hazards. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.
Section 9. Physical & Chemical Data
Appearance: White/pink solid.
Odor: Phenolic.
Odor threshold: Not available.
pH: Not available.
Relative density: 1.37 @ 20C.
Melting Point: 64C-67C literature.
Initial boiling point and boiling range: 235C literature.
Flash point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility(ies): 3.8 g/l @20C in water.
Viscosity: Not available.
Chemical Formula: C7H7ClO or ClC6H3(CH3)OH
Molecular Weight: 142.58
Section 10. Stability and Reactivity
Chemical Stability: Stable under normal temperatures and pressures.
Incompatibility (Materials to Avoid): Oxidizing agents, copper and alloys.
Conditions to Avoid: Incompatible materials, excessive heat.
Hazardous Decomposition Products: Fumes may evolve along with carbon oxides and hydrogen chloride.
Hazardous Polymerization: Will not occur.
Section 11. Toxicological Information
Toxicity to Animals:
LC50 Inhalation - Rat - 4 h – >287 mg/l
LD50 Oral - Rat - 1830 mg/kg
LD50 Dermal - Rat - female - 2.000 mg/kg
Carcinogenicity: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC, NTP ACGIH or OSHA.
Mutagenic Effects: No information found.
Reproductive Effects: No information found.
Developmental Toxicity: No information found.
Section 12. Ecological Information
Ecotoxicity: Very toxic to aquatic organisms.
Toxicity to fish: semi-static test LC50 - Oncorhynchus mykiss (rainbow trout) - 0,92 mg/l - 96,0 h.
Toxicity to daphnia and other aquatic invertebrates: static test EC50 - Daphnia magna (Water flea) - 2,29 mg/l - 48 h.
Persistence and Degradability: Degradable.
Mobility: Likely to be mobile.
Bioaccumulation/ Accumulation: No information available.
Results of PBT and vPvB assessment: No data available for assessment.
Section 13. Disposal Suggestions
Dispose of in accordance with all applicable local, state and federal regulations at an approved waste disposal facility.
Section 14. Transport and Label Information
DOT USA, TDG Canada & ADR/RID Europe:
UN-No UN 3077
Proper Shipping Name: Environmentally hazardous substance, solid, n.o.s. (Chlorocresol)
Hazard Class 9, Packing Group III
IMDG/IMO
UN-No UN 3077
Proper Shipping Name: Environmentally hazardous substance, solid, n.o.s. (Chlorocresol)
Hazard Class 9, Packing Group III
IATA:
UN-No UN 3077
Proper Shipping Name: Environmentally hazardous substance, solid, n.o.s. (Chlorocresol)
Hazard Class 9, Packing Group III
Section 15. Regulatory Information
USA:
SARA 302: No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302.
SARA 311/312: Acute Health Hazard; Chronic Health Hazard, as per section 2.
California Prop.65: This product contains no chemical known to the State of California to cause birth defects or other reproductive harm.
Section 16. Other Information
European Labeling in Accordance with EC Directives:
H302 + H312 Harmful if swallowed or in contact with skin.
H317 May cause an allergic skin reaction.
H318 Causes serious eye damage.
H400 Very toxic to aquatic life.
Hazard Symbols:
C Corrosive
Xn Harmful
N Dangerous for the environment
Risk Phrases:
R21/22 Harmful in contact with skin and if swallowed.
R41 Risk of serious damage to eyes.
R43 May cause sensitization by skin contact.
R50 Very toxic to aquatic organisms.
Disclaimer:
**************************
Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
**************************