Cetyltrimethylammonium bromide or Hexadecyl(trimethyl)ammonium bromide or Cetrimonium bromide or CTAB or Cetyl trimethyl ammonium bromide Manufacturers, with SDS GHS MSDS Sheet

Supplier, Manufacturer, Exporter of Cetyltrimethylammonium bromide or Cetrimonium bromide, Muby Chemicals of Mubychem Group, established in 1976, is the original manufacturers of Specialty Chemicals, Pharmaceutical Excipient, Fragrance Food & Flavor chemicals, Reagent Grade Chemicals, Shale Gas Fracturing Chemicals in India. Mubychem Group has several manufacturing facilities spread across Western India and world wide contacts and toll manufacturers. We are exporting globally to countries like USA, Canada, Europe, UAE, South Africa, Tanzania, Kenya, Egypt, Nigeria, Cameroon, Uganda, Turkey, Mexico, Brazil, Chile, Argentina, Dubai, Korea, Vietnam, Thailand, Malaysia, Indonesia, Australia, China, Germany, France, Italy, Portugal etc.

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Cetyltrimethylammonium bromide  or Hexadecyl(trimethyl)ammonium bromide or Cetrimonium bromide or CTAB or Cetyl trimethyl ammonium bromide: CAS Number: 57-09-0, EINECS EC Number: 200-311-3, Molecular Formula: C19H42BrN, Molecular Weight: 364.45, HS Code ---**

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SDS MSDS Sheet of Cetyltrimethylammonium bromide  or Hexadecyl(trimethyl)ammonium bromide or Cetrimonium bromide or CTAB or Cetyl trimethyl ammonium bromide Manufacturers

Cetyltrimethylammonium bromide
Hexadecyl(trimethyl)ammonium bromide or Cetrimonium bromide or CTAB or Cetyl trimethyl ammonium bromide Pure Suppliers
Cetyltrimethylammonium Bromide

Cetrimonium bromide or Cetyltrimethylammonium bromide or Hexadecyltrimethylammonium bromide or CTAB or Cetyl trimethyl ammonium bromide  is a quaternary ammonium surfactant. It is one of the components of the topical antiseptic cetrimide. The cetrimonium (hexadecyltrimethylammonium) cation is an effective antiseptic agent against bacteria and fungi.

General Properties and Specifications of Cetyltrimethylammonium bromide  or Cetyl trimethyl ammonium bromide  or Hexadecyl(trimethyl)ammonium bromide or Cetrimonium bromide or CTAB:
Appearance: White crystalline solid.
Assay: 99% minimum
Melting point: 243C to 251C literature.
Boiling point: Decomposes literature.
Flash point; 244C literature.
Storage: 15C to 30C. Shipping at Ambient Temperature.


Specifications of Cetrimonium Bromide USP NF Grade:
C19H42BrN --- 364.45
Hexadecyltrimethylammonium bromide --- [CAS 57-09-0].

DEFINITION
Cetrimonium Bromide contains NLT 96.0% and NMT 101.0% of hexadecyltrimethylammonium bromide, calculated as C19H42BrN, on the dried basis.

IDENTIFICATION
A. Ultraviolet Absorption:
Sample solution: 10 mg/mL in alcohol
Analytical wavelength: 260–280 nm
Cell: 1 cm
Acceptance criteria: After correcting for the blank, the absorbance is NMT 0.05.
B.
Sample solution: Dissolve 5 mg of Cetrimonium Bromide in 5 mL of phosphate buffer pH 8.0.
Blank: 5 mL of phosphate buffer pH 8.0
Analysis: Add a strip of methyl green–iodomercurate paper to the Sample solution and Blank.
Acceptance criteria: After 5 min, the Sample solution shows a more intense greenish-blue color than the Blank.
C.
Sample: 2.0 g
Analysis: Transfer the Sample to a 100-mL flask, and dissolve in and dilute with previously boiled and cooled water to volume.
Acceptance criteria: The solution froths copiously when shaken.
D. Thin-Layer Chromatographic Identification Test:
Acceptance criteria: The principal spot of the Sample solution is similar in position, color, and size to that of the Standard solution.
E. Identification Tests—General, Bromide: A solution of it meets the requirements.

ASSAY
To pass the test.
Acceptance criteria: 96.0%–101.0% on the dried basis

Residue on Ignition:
Sample: 1.0 g
Acceptance criteria: NMT 0.5%
Limit of Amines and Amine Salts:
To pass the test.
Acceptance criteria: If the curve shows two inflection points, the volume of titrant added between the two points is NMT 2.0 mL.
Microbial Enumeration Tests and Tests for Specified Microorganisms: The total aerobic microbial count is NMT 1000 cfu/g. The total combined molds and yeasts count is NMT 10 cfu/g.
Appearance of Solution:
Analysis: Transfer 2.0 g of Cetrimonium Bromide to a 100-mL flask, and dissolve in and dilute with previously boiled and cooled water to volume.
Acceptance criteria: The solution is clear and colorless.
Acidity or Alkalinity:
Sample solution: 50 mL of the solution obtained in the Appearance of Solution test
Analysis: To the Sample solution add 0.1 mL of bromocresol purple.
Acceptance criteria: NMT 0.1 mL of 0.1 N sodium hydroxide or 0.1 N hydrochloric acid is required to change the color of the indicator.
Loss on Drying:
Sample: 1.0 g
Analysis: Dry at 105C for 2 h.
Acceptance criteria: NMT 2.0%
Packaging and Storage: Preserve in well-closed containers. No storage requirements specified.

For Original Monographs of IP Indian Pharmacopoeia BP British Pharmacopoeia USP US Pharmacopoeia FCC Food Grade product, please check with the respective web-pages or books.

We also manufacture and supply Cetrimide.

Hexadecyl(trimethyl)ammonium bromide or Cetrimonium bromide or CTAB Manufacturers

Manufacturers:

MUBY CHEMICALS
Ambernath Mumbai, Ankleshwar Gujarat, India
TEL: (OFFICE) +912223770100, +912223726950
Current Date Time in India GMT+5:30

e-mail: info@mubychem.com

USA, Canada, Mexico and other American
neighbouring buyers may
e-mail: us@mubychem.com
Call toll-free 1-844-682-9243 (1-844-MUBYCHEM)

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Last 25 August, 2022

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Cetyltrimethylammonium bromide  or Hexadecyl(trimethyl)ammonium bromide or Cetrimonium bromide or CTAB or Cetyl trimethyl ammonium bromide SDS, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet
08-Oct-20

1. Product Identification

Product Name & Other Names: Cetyltrimethylammonium bromide  or Hexadecyl(trimethyl)ammonium bromide or Cetrimonium bromide or CTAB or Cetyl trimethyl ammonium bromide.
CAS No.: 57-09-0
EINECS EC-No.: 200-311-3
Molecular Weight: 364.45
Chemical Formula: C19H42BrN
Relevant uses and uses advised against (if any): Industrial use only.
Supplier: As per letterhead.

2. Hazards Identification

GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008

Acute toxicity, Oral Category 4 - H302
Skin irritation Category 2 - H315
Skin corrosion/irritation Category 2 - H318
Specific target organ toxicity - single exposure Category 3, Respiratory system - H335
Specific target organ toxicity - repeated exposure, Oral Category 2, Gastrointestinal tract - H373
Short-term (acute) aquatic hazard Category 1, H400

Labeling according Regulation (EC) No 1272/2008

GHS Label Elements
corrosive.png
Corrosive

GHS Label Elements
A close up of a sign  Description automatically generated
Aquatic Toxicity

GHS Label Elements
A picture containing drawing, box  Description automatically generated
Health Hazard

Signal Words: Danger

Hazard statements:
H302: Harmful if swallowed.
H315 Causes skin irritation.
H318: Causes serious eye damage.
H335: May cause respiratory irritation.
H373: May cause damage to organs (Gastrointestinal tract) through prolonged or repeated exposure if swallowed.
H400: Very toxic to aquatic life.

Precautionary statements:
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P262: Do not get in eyes, on skin, or on clothing.
P264 Wash skin thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P273 Avoid release to the environment.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P314: Get Medical advice/attention if you feel unwell.
P330: Rinse mouth.
P301+P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P302+352: IF ON SKIN: Wash with soap and water.
P332+313: If skin irritation occurs: Get medical advice/attention.
P304+340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305+ P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+P313 If eye irritation persists: Get medical advice/ attention.
P360: Rinse immediately contaminated clothing and skin with plenty of water before removing clothes.
P501 Dispose of contents/ container to an approved waste disposal plant.

Classification according to EU Directives 67/548/EEC or 1999/45/EC:
Hazard Symbols:
Xn = Harmful
C = Corrosive.
Xi Irritant
N Dangerous for the environment
Risk Phrases:
R22 Harmful if swallowed.
R37/38 Irritating to respiratory system and skin.
R41 Risk of serious damage to eyes.
R48 Danger of serious damage to health by prolonged exposure.
R50 Very toxic to aquatic organisms.

3. Composition/Information on Ingredients

Product Name & Other Names: Cetyltrimethylammonium bromide  or Hexadecyl(trimethyl)ammonium bromide or Cetrimonium bromide or CTAB or Cetyl trimethyl ammonium bromide.
CAS No.: 57-09-0
EINECS EC-No.: 200-311-3

4. First Aid Measures

Always seek medical attention after first aid measures are provided.
Inhalation: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.
Ingestion: Give large amounts of water to drink. Never give anything by mouth to an unconscious person. Get medical attention.
Skin Contact: Immediately flush skin with plenty of water for at least 15 minutes. Remove contaminated clothing and shoes. Get medical attention. Wash clothing before reuse. Thoroughly clean shoes before reuse.
Eye Contact: Check for and remove any contact lenses. Immediately flush eyes with running water for at least 15 minutes, keeping eyelids open. Cold water may be used. Get medical attention.

5. Fire Fighting Measures

Auto ignition temperature: Combustible.
Specific Hazards Arising from the Chemical: Dust can form an explosive mixture with air. Do not allow run-off from firefighting to enter drains or water courses. Fine dust dispersed in air may ignite.
Fire Extinguishing Media: Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. Avoid solid stream of water. Water spray may be used to keep fire exposed containers cool. Carbon dioxide and carbon monoxide, Nitrogen oxides (NOx), Hydrogen bromide will be formed on combustion.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. Suppress (knock down) gases/vapors/mists with a water spray jet.

6. Accidental Release Measures

Personal precautions, protective equipment and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental  precautions: Do not let the product enter drains, soil or water sources.
Methods and materials used for containment Cleanup procedures and Storage:
Small Spill: Mop up and place in an appropriate waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to local and regional authority requirements.
Large Spill: Keep away from heat. Keep away from sources of ignition. Stop leak if without risk. Pick up and dispose of as hazardous waste. Keep in suitable, closed containers for disposal. Finish cleaning by spreading water on the contaminated surface and dispose as per law.

7. Handling and Storage

Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. Wash thoroughly after handling. Do not drink, eat or smoke while handling. Avoid contact with skin, eyes and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cool, dry and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Do not leave the material container open. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like strong oxidizing agents. Storage: 15C to 30C. Shipping at ambient temperature.

8. Exposure Controls/Personal Protection

Airborne Exposure Limits: This product does not contain any hazardous materials with occupational exposure limits established by the region-specific regulatory bodies. Keep below 5 mg/m3.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Dust deposits on floors and other surfaces may pick up moisture and cause the surfaces to become slippery and present safety hazards. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.

9. Physical and Chemical Properties

Appearance: White crystalline solid.
Odor: Not available.
Odor threshold: Not available.
pH: 5 - 7
Relative density: Not available.
Boiling Point: Decomposes literature.
Melting Point: 243C to 251C literature.
Flash point: 244C literature.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor Density (Air=1): Not available.
Vapor Pressure (mm Hg): Not available.
Evaporation Rate (BuAc=1): Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility: Soluble in water.
Viscosity: Not available.
Molecular Weight: 364.45
Chemical Formula: C19H42BrN

10. Stability and Reactivity

Stability: Stable under ordinary conditions of use and storage.
Hazardous Decomposition Products: Fumes, Carbon dioxide and carbon monoxide, Nitrogen oxides (NOx) and Hydrogen bromide may form when heated to decomposition.
Hazardous Polymerization: Not reported.
Incompatibilities: Strong oxidizing agents.
Conditions to Avoid: Heat, flames, ignition sources and incompatibles. Avoid dust formation, Excess heat. Exposure to atmosphere. Strongly hygroscopic.

11. Toxicological Information

Oral rat LD50: 410 mg/kg.
Dermal rabbit LD50: 2150 mg/kg.
Mutagenic Effects: Not available.
Teratogenic Effects: Not available.
Developmental Toxicity: Not available.
Carcinogenicity: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC, ACGIH, OSHA, NTP.

12. Ecological Information

Toxicity to fish: semi-static test LC50 - Danio rerio (zebra fish) – 0.2 mg/l  - 96 h.
Toxicity to daphnia and other aquatic invertebrates: semi-static test EC50 - Daphnia magna (Water flea) – 0.032 mg/l  - 48 h.
Persistence and Degradability: Persistence is unlikely due to water solubility.
Mobility: Mobility likely due to water solubility.

13. Disposal Considerations

Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. State and local disposal regulations may differ from federal disposal regulations. Dispose of container and unused contents in accordance with law.

14. Transport Information

DOT-USA, Canada TDG & ADR/RID Europe:
UN number: 3077; Transport hazard class(es): 9; Packing group: III
UN proper shipping name: Environmentally hazardous substance, solid, n.o.s. (Cetrimonium bromide)
IMDG & IATA:
UN proper shipping name: Environmentally hazardous substance, solid, n.o.s. (Cetrimonium bromide)

15. Regulatory Information

USA:
SARA 311/312
: Acute: and Chronic as per section 2.
SARA 302 Extremely Hazardous Substance: None present in regulated quantities.
SARA 304 Emergency Release Notification: None present in regulated quantities.
US California Proposition 65: No ingredient regulated by CA Prop 65 present.


16. Other Information

Classification according to EU Directives 67/548/EEC or 1999/45/EC:
Hazard Symbols:
Xn = Harmful
C = Corrosive.
Xi Irritant
N Dangerous for the environment
Risk Phrases:
R22 Harmful if swallowed.
R37/38 Irritating to respiratory system and skin.
R41 Risk of serious damage to eyes.

Disclaimer:
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Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
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