Tyloxapol USP Grade Manufacturers, with SDS GHS MSDS Sheet |
Supplier, Manufacturer, Exporter of Tyloxapol USP Grade, Muby Chemicals of Mubychem Group, established in 1976, is the original manufacturers of Specialty Chemicals, Pharmaceutical Excipient, Fragrance Food & Flavor chemicals, Reagent Grade Chemicals, Shale Gas Fracturing Chemicals in India. Mubychem Group has several manufacturing facilities spread across Western India and world wide contacts and toll manufacturers. We are exporting globally to countries like USA, Canada, Europe, UAE, South Africa, Tanzania, Kenya, Egypt, Nigeria, Cameroon, Uganda, Turkey, Mexico, Brazil, Chile, Argentina, Dubai, Korea, Vietnam, Thailand, Malaysia, Indonesia, Australia, Russia, Ukraine, China, Germany, France, Italy Portugal, Bangladesh, etc. The products are offered as per required specifications and in correct shape and size in mm or meshs or microns as specified by the buyer. The participating units have one or more accreditations like FDA - cGMP and GLP approval, ISO-9001 Certified, "REACH" Registered, ISO-14001, ISO/IEC 17025, ISO-22000, FSSC 22000, ISO 45001, Kosher Certified, Halal Certified, HACCP, FSSAI. We offer Commercial Pure & IP BP EP Ph Eur USP NF JP FCC Food Grade Analytical Reagent Grades of Chemicals |
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Tyloxapol CAS Number 25301-02-4, EINECS EC Number: 684-193-2 PubChem, Molecular Formula: (C15H21O(C2H4O)m)n, Molecular Weight: yy, HS Code 29420090 or 25301-02-4 or 3909400000 or 3402420090
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Specifications, Safety Data Sheet, Manufacturing process details, Wholesale retail buy sell prices, Uses etc available on line in these pages for Tyloxapol.
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SDS MSDS Sheet of Tyloxapol Manufacturers
Tyloxapol
Phenol, 4-(1,1,3,3-tetramethylbutyl)-, polymer with formaldehyde and oxirane; p-(1,1,3,3-Tetramethylbutyl)phenol polymer with ethylene oxide and formaldehyde Suppliers
Tyloxapol or 4-(1,1,3,3-Tetramethylbutyl)phenol polymer with formaldehyde and oxirane is a non-ionic liquid polymer used mainly as a surfactant, a pharmaceutical excipient, and an experimental research tool. It is injected in laboratory settings to inhibit lipoprotein lipase, creating animal models of hyperlipidemia (high blood fats) and atherosclerosis.
General Properties and Specifications of Tyloxapol or 4-(1,1,3,3-Tetramethylbutyl)phenol Polymer with Formaldehyde and Oxirane:
Appearance: Clear to hazy, yellow-to-amber viscous liquid.
Odor: Slight aromatic odor.
Solubility: Soluble in water-challenging solvents like methanol, chloroform, and DMSO, but USP grades work effectively as aqueous dispersants.
Cloud Point: Between 92C and 97C.
Microbial limits:
To pass the test.
Storage: Tightly closed, preferably <20C. Short term shipping may be ambient.
Tyloxapol USP Grade Specifications:
Phenol, 4-(1,1,3,3-tetramethylbutyl)-, polymer with formaldehyde and oxirane;
p-(1,1,3,3-Tetramethylbutyl)phenol polymer with ethylene oxide and formaldehyde
CAS 25301-02-4
UNII: Y27PUL9H56
DEFINITION
Tyloxapol is a nonionic liquid polymer of the alkyl aryl polyether alcohol type. [Note— Precautions should be exercised to prevent contact of Tyloxapol with metals.]
IDENTIFICATION
A. Infrared Absorption.
Limit of Anionic Detergents: To pass the test.
Limit of Ethylene Oxide: To pass the test. Acceptance criteria: NMT 10 µg/g.
Limit of Formaldehyde: To pass the test.
Free Phenol: To pass the test.
Cloud Point: To pass the test. Acceptance criteria: The cloud point is between 92C and 97C.
pH: Sample solution: 50 mg/mL. Acceptance criteria: 4.0–7.0
Packaging and Storage: Preserve in tight containers.
For Original Monographs of IP Indian Pharmacopoeia EP Ph Eur European Pharmacopoeia BP British Pharmacopoeia USP US Pharmacopoeia FCC Food Grade product, please check with the respective web-pages or books.
We also manufacture and supply as under:
Manufacturers:
MUBY CHEMICALS
Ambernath Mumbai, Ankleshwar Gujarat, India
TEL: (OFFICE) +91-22-65290100, +91-22-65290101
Current Date Time in India GMT+5:30
e-mail: ask@mubychem.com
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Last 30 September, 2026
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Tyloxapol SDS, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet
1. Product Identification
Product Name & Other Names: Tyloxapol or Phenol, 4-(1,1,3,3-tetramethylbutyl)-, polymer with formaldehyde and oxirane or p-(1,1,3,3-Tetramethylbutyl)phenol polymer with ethylene oxide and formaldehyde Suppliers.
CAS No.: 25301-02-4
EINECS EC Number: 684-193-2 PubChem.
Molecular Formula: (C15H21O(C2H4O)m)n
Relevant uses and uses advised against (if any): Industrial Manufacturing.
Suppliers: As per letterhead.
2. Hazards Identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Hazard Class and Category Code(s), Regulation (EC) No 1272/2008 (CLP)
Skin irritation Category 2, H315
Serious eye damage/eye irritation Category 2A, H319
Specific target organ toxicity - single exposure, Target Organs - Respiratory system. Category 3, H335
Labeling Regulation EC 1272/2008 (CLP) & GHS
GHS Label Elements Irritant |
Signal Words: Warning
Hazard statements:
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
Precautionary statements:
P264: Wash … thoroughly after handling.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352: IF ON SKIN: Wash with plenty of soap and water.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P332+P313: If skin irritation occurs: Get medical advice/attention.
P337+P313: If eye irritation persists: Get medical advice/ attention.
P362: Take off contaminated clothing and wash before reuse.
Classification according to EU Directives 67/548/EEC or 1999/45/EC:
Hazard Symbol:
Xi = Irritant
Risk Phrase:
R36/37/38 Irritating to eyes, respiratory system, and skin.
3. Composition/Information on Ingredients
Product Name & Other Names: Tyloxapol or Phenol, 4-(1,1,3,3-tetramethylbutyl)-, polymer with formaldehyde and oxirane or p-(1,1,3,3-Tetramethylbutyl)phenol polymer with ethylene oxide and formaldehyde Suppliers.
CAS No.: 25301-02-4
EINECS EC Number: 684-193-2 PubChem.
4. First Aid Measures
Always seek medical attention after first aid measures are provided.
Inhalation: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen and get medical attention immediately.
Ingestion: Never give anything by mouth to an unconscious person. Get medical attention.
Skin Contact: Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Get medical attention. Wash clothing and shoes before reuse.
Eye Contact: Immediately flush eyes with plenty of water for at least 15 minutes, lifting lower and upper eyelids occasionally. Get medical attention immediately.
5. Fire Fighting Measures
Fire: As with most organic solids, fire is possible at elevated temperatures or by contact with an ignition source.
Explosion: Fine dust dispersed in air in sufficient concentrations, and in the presence of an ignition source is a potential dust explosion hazard.
Fire Extinguishing Media: Water spray, dry chemical, alcohol foam, or carbon dioxide.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes.
6. Accidental Release Measures
Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment cleanup procedures and Storage:
Small Spill: Use appropriate tools to put the spilled solid in a convenient waste disposal container.
Large Spill: Corrosive solid. Contain spilled material. Stop leak if without risk. Do not get water inside container. Do not touch spilled material. Use water spray to reduce vapor. Prevent entry into sewers, basements, or confined areas; dike if needed. Eliminate all ignition sources.
7. Handling and Storage
Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. Wash thoroughly after handling it. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original containers. Keep air contact to a minimum. Do not leave the material container open. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store it with incompatible materials like strong oxidizers. Storage: Tightly closed, preferably <20C. Short term shipping may be ambient.
8. Exposure Controls/Personal Protection
Airborne Exposure Limits: No information found.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator (NIOSH type N95 or better filters) may be worn. If oil particles (e.g., lubricants, cutting fluids, glycerin, etc.) are present, use a NIOSH type R or P filter. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator.
Skin Protection: Wear impervious protective clothing, including boots, gloves, lab coat, apron or coveralls, as appropriate, to prevent skin contact.
Eye Protection: Use chemical safety goggles and/or full-face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.
9. Physical and Chemical Properties
Appearance: Clear to hazy, yellow-to-amber viscous liquid.
Odor: Slight aromatic odor.
Odor threshold: Not available.
pH: 4.0–7.0
Relative density: Not available.
Boiling Point: Not available.
Melting Point: Not available..
Flash point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor Density (Air=1): Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility: Soluble in water-challenging solvents like methanol, chloroform, and DMSO, but USP grades work effectively as aqueous dispersants.
Viscosity: Not available.
Molecular Formula: (C15H21O(C2H4O)m)n
10. Stability and Reactivity
Stability: Stable under recommended conditions of use and storage.
Hazardous Decomposition Products: Fumes, carbon dioxide and carbon monoxide may form when heated to decomposition.
Hazardous Polymerization: Will not occur.
Incompatibilities: Strong oxidizers.
Conditions to Avoid: Heat, dusting, and incompatibles.
11. Toxicological Information
Toxicity to Animals: Not available.
Carcinogenicity: This product is not classifiable as to its carcinogenicity based on its IARC, ACGIH, NTP, or EPA classification.
Mutagenic Effects: Not available.
Developmental Toxicity: Not available.
Reproductive Effects: No information available.
12. Ecological Information
Toxicity to fish: Not available.
Environmental Toxicity: No information found.
Persistence and degradability: Unlikely to persist due to water solubility.
Mobility in soil: Likely to be mobile due to water solubility.
13. Disposal Considerations
Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility.
14. Transport Information
DOT USA, TDG Canada & ADR/RID Europe: Not Regulated.
IMDG & IATA: Not Regulated.
15. Regulatory Information
USA:
SARA 311/312 Hazards: Acute Health Hazard.
California Prop. 65 Components: Not listed.
Section 16 - Additional Information
European Labeling in Accordance with EC Directives:
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
Classification according to EU Directives 67/548/EEC or 1999/45/EC:
Hazard Symbol:
Xi = Irritant
Risk Phrase:
R36/37/38 = Irritating to eyes, respiratory system, and skin.
Disclaimer:
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Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
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