Macrogol Cetostearyl Ether BP Ph Eur Grade Manufacturers, with SDS GHS MSDS Sheet |
Supplier, Manufacturer, Exporter of Macrogol Cetostearyl Ether BP Ph Eur, Muby Chemicals of Mubychem Group, established in 1976, is the original manufacturers of Specialty Chemicals, Pharmaceutical Excipient, Fragrance Food & Flavor chemicals, Reagent Grade Chemicals, Shale Gas Fracturing Chemicals in India. Mubychem Group has several manufacturing facilities spread across Western India and world wide contacts and toll manufacturers. We are exporting globally to countries like USA, Canada, Europe, UAE, South Africa, Tanzania, Kenya, Egypt, Nigeria, Cameroon, Uganda, Turkey, Mexico, Brazil, Chile, Argentina, Dubai, Korea, Vietnam, Thailand, Malaysia, Indonesia, Australia, China, Germany, France, Italy, Portugal, Bangladesh, etc. The products are offered as per required specifications and in correct shape and size in mm or meshs or microns as specified by the buyer. The participating units have one or more accreditations like FDA - cGMP and GLP approval, ISO-9001 Certified, "REACH" Registered, ISO-14001, ISO/IEC 17025, ISO-22000, FSSC 22000, ISO 45001, Kosher Certified, Halal Certified, HACCP, FSSAI. We offer Commercial Pure & IP BP EP Ph Eur USP NF JP FCC Food Grade Analytical Reagent Grades of Chemicals |
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Macrogol Cetostearyl Ether CAS Number 68439-49-6, EINECS EC Number: 500-212-8
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SDS MSDS Sheet of Macrogol Cetostearyl Ether Manufacturers
Macrogol Cetostearyl Ether
BP Ph Eur Grade Suppliers
Macrogol Cetostearyl Ether BP Ph Eur Grade Specifications:
Action and use: Non-ionic surfactant.
DEFINITION
Mixture of ethers of mixed macrogols with linear fatty alcohols, mainly cetostearyl alcohol. It may contain some free macrogols and it contains various amounts of free cetostearyl alcohol. The number of moles of ethylene oxide reacted per mole of cetostearyl alcohol is 2 to 33 (nominal value).
CHARACTERS
Appearance: White or yellowish-white, waxy, unctuous mass, pellets, microbeads or flakes.
Solubility:
- macrogol cetostearyl ether with low numbers of moles of ethylene oxide reacted per mole: practically insoluble in water, soluble in ethanol (96 per cent) and in methylene chloride;
- macrogol cetostearyl ether with higher numbers of moles of ethylene oxide reacted per mole: dispersible or soluble in water, soluble in ethanol (96 per cent) and in methylene chloride.
It solidifies at 32C to 52C.
IDENTIFICATION
A. Hydroxyl value. To pass the test.
B. Iodine value. To pass the test.
C. Saponification value. To pass the test.
D. Thin-layer chromatography. To pass the test.
E. Dissolve or disperse 0.1 g in 5 mL of ethanol (96 per cent) add 2 mL of water, 10 mL of dilute hydrochloric acid, 10 mL of barium chloride solution and 10 mL of a 100 g/L solution of phosphomolybdic acid. A precipitate is formed.
Hydroxyl value: To meet the test.
Iodine value: Maximum 2.0.
Saponification value: Maximum 3.0, determined on 10.0 g.
Ethylene oxide and dioxan: Maximum 1 ppm of ethylene oxide and maximum 10 ppm of dioxan.
Water: Maximum 3.0 per cent, determined on 2.00 g.
Total ash: Maximum 0.2 per cent, determined on 2.0 g.
For Original Monographs of IP Indian Pharmacopoeia EP Ph Eur European Pharmacopoeia BP British Pharmacopoeia USP US Pharmacopoeia FCC Food Grade product, please check with the respective web-pages or books.
We also manufacture and supply as under:
Macrogol 20 Glycerol Monostearate.
Manufacturers:
MUBY CHEMICALS
Ambernath Mumbai, Ankleshwar Gujarat, India
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Macrogol Cetostearyl Ether SDS, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet 09-Mar-24
1. Product Identification
Product Name & Other Names: Macrogol Cetostearyl Ether.
CAS No.: 68439-49-6
EINECS EC-No.: 500-212-8
Relevant uses and uses advised against (if any): Industrial use only.
Supplier: As per letterhead.
2. Hazards Identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008
Acute toxicity, Oral Category 4 - H302
Skin irritation Category 2 - H315
Skin corrosion/irritation Category 2 - H318
Long-term (chronic) aquatic hazard Category 1, H410
Labeling according to Regulation (EC) No 1272/2008
GHS Label Elements  Corrosive |
GHS Label Elements |
Signal Words: Danger
Hazard statements:
H302: Harmful if swallowed.
H315 Causes skin irritation.
H318: Causes serious eye damage.
H410 Very toxic to aquatic life with long lasting effects.
Precautionary statements:
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P262: Do not get in eyes, on skin, or on clothing.
P264 Wash skin thoroughly after handling.
P270 Do not eat, drink, or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P273 Avoid release to the environment.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P314: Get Medical advice/attention if you feel unwell.
P330: Rinse mouth.
P301+P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P302+352: IF ON SKIN: Wash with soap and water.
P332+313: If skin irritation occurs: Get medical advice/attention.
P304+340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+P313: If eye irritation persists: Get medical advice/ attention.
P360: Rinse immediately contaminated clothing and skin with plenty of water before removing clothes.
P501: Dispose of contents/ container to an approved waste disposal plant.
Classification according to EU Directives 67/548/EEC or 1999/45/EC:
Hazard Symbols:
Xn = Harmful
C = Corrosive
N = Dangerous for the environment
Risk Phrases:
R22 Harmful if swallowed.
R38: Irritating to skin.
R41 Risk of serious damage to eyes.
R51/53 Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
3. Composition/Information on Ingredients
Product Name & Other Names: Macrogol Cetostearyl Ether.
CAS No.: 68439-49-6
EINECS EC-No.: 500-212-8
4. First Aid Measures
Always seek medical attention after first aid measures are provided.
Inhalation: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.
Ingestion: Give large amounts of water to drink. Never give anything by mouth to an unconscious person. Get medical attention.
Skin Contact: Immediately flush skin with plenty of water for at least 15 minutes. Remove contaminated clothing and shoes. Get medical attention. Wash clothing before reuse. Thoroughly clean shoes before reuse.
Eye Contact: Check for and remove any contact lenses. Immediately flush eyes, with running water for at least 15 minutes, keeping eyelids open. Cold water may be used. Get medical attention.
5. Fire Fighting Measures
Auto ignition temperature: High heat or direct flame is necessary to cause ignition.
Specific Hazards Arising from the Chemical: Dust can form an explosive mixture with air. Do not allow run-off from firefighting to enter drains or water courses. Fine dust dispersed in air may ignite.
Fire Extinguishing Media: Use water spray, alcohol-resistant foam, dry chemical, or carbon dioxide. Avoid solid stream of water. Water spray may be used to keep fire exposed containers cool. Carbon dioxide and carbon monoxide and fumes will be formed on combustion.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes.
6. Accidental Release Measures
Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment cleanup procedures and Storage:
Small Spill: Mop up and place in an appropriate waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to local and regional authority requirements.
Large Spill: Keep away from heat. Keep away from sources of ignition. Stop leaking, without risk. Pick up and dispose of hazardous waste. Keep in suitable, closed containers for disposal. Finish cleaning by spreading water on the contaminated surface and dispose as per law.
7. Handling and Storage
Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Do not leave the material container open. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like strong oxidizing agents.
8. Exposure Controls/Personal Protection
Airborne Exposure Limits: Not established. Keep below 5 mg/m3.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area. Please refer to the ACGIH document, Industrial Ventilation, A Manual of Recommended Practices, most recent edition, for details.
Personal Respirators (NIOSH Approved): Use only under a chemical fume hood. For conditions of use where exposure to the substance is apparent and engineering controls are not feasible, consult an industrial hygienist. For emergencies, or instances where the exposure levels are not known, use a full-face piece positive-pressure, air-supplied respirator. WARNING: Air purifying respirators do not protect workers in oxygen-deficient atmospheres.
Skin Protection: Wear impervious protective clothing, including boots, gloves, lab coat, apron, or coveralls, as appropriate, to prevent skin contact.
Eye Protection: Use chemical safety goggles and/or a full-face shield where splashing is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.
9. Physical and Chemical Properties
Appearance: White or yellowish-white, waxy, unctuous mass, pellets, microbeads or flakes.
Odor: Not available.
Odor threshold: Not available.
pH: Not available.
Relative density: Not available.
Boiling Point: Not available.
Melting Point: 32C to 52C
Flash point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor Density (Air=1): Not available.
Vapor Pressure (mm Hg): Not available.
Evaporation Rate (BuAc=1): Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility: Soluble in ethanol (96 per cent) and in methylene chloride.
Viscosity: Not available.
10. Stability and Reactivity
Stability: Stable under ordinary conditions of use and storage.
Hazardous Decomposition Products: Fumes, Carbon dioxide and carbon monoxide may form when heated to decomposition.
Hazardous Polymerization: Not reported.
Incompatibilities: Strong oxidizing agents.
Conditions to Avoid: Heat, flames, ignition sources and incompatibles. Avoid dust formation, Excess heat. Exposure to light and Exposure to atmosphere.
11. Toxicological Information
Oral rat LD50: 1260 mg/kg.
Mutagenic Effects: Not available.
Teratogenic Effects: Not available.
Developmental Toxicity: Not available.
Carcinogenicity: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible, or confirmed human carcinogen by IARC, ACGIH, OSHA, NTP.
12. Ecological Information
Very toxic to aquatic life with long lasting effects.
Toxicity to fish: semi-static test LC50 - Danio rerio (zebra fish) - 108 mg/l - 96 h.
Persistence and Degradability: No data available.
Mobility: No data available.
Results of PBT and vPvB assessment: No data available for assessment.
13. Disposal Considerations
Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. Processing use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose of container and unused contents in accordance with law.
14. Transport Information
DOT-USA, Canada TDG & ADR/RID Europe:
UN number: 3077; Transport hazard class(es): 9; Packing group: III
UN proper shipping name: Environmentally hazardous substance, solid, n.o.s. (alcohols, C16-C18, ethoxylated).
IMDG & IATA:
UN number: 3077; Transport hazard class(es): 9; Packing group: III
UN proper shipping name: Environmentally hazardous substance, solid, n.o.s. (alcohols, C16-C18, ethoxylated).
15. Regulatory Information
USA:
SARA 311/312: Acute: and Chronic as per section 2.
US California Proposition 65: No ingredient regulated by CA Prop 65 present.
16. Other Information
European Labeling in Accordance with EC Directives:
H302: Harmful if swallowed.
H315 Causes skin irritation.
H318: Causes serious eye damage.
H410 Very toxic to aquatic life with long lasting effects.
Hazard Symbols:
Xn = Harmful
C = Corrosive
N = Dangerous for the environment
Risk Phrases:
R22 Harmful if swallowed.
R38: Irritating to skin.
R41 Risk of serious damage to eyes.
R51/53 Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Disclaimer:
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Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
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