Arginine or L-Arginine, low endotoxin, low metal Manufacturers, with SDS GHS MSDS Sheet |
Supplier, Manufacturer, Exporter of Arginine or L-Arginine, low endotoxin, low metal, Muby Chemicals of Mubychem Group, established in 1976, is the original manufacturers of Specialty Chemicals, Pharmaceutical Excipient, Fragrance Food & Flavor chemicals, Reagent Grade Chemicals, Shale Gas Fracturing Chemicals in India. Mubychem Group has several manufacturing facilities spread across Western India and world wide contacts and toll manufacturers. We are exporting globally to countries like USA, Canada, Europe, UAE, South Africa, Tanzania, Kenya, Egypt, Nigeria, Cameroon, Uganda, Turkey, Mexico, Brazil, Chile, Argentina, Dubai, Korea, Vietnam, Thailand, Malaysia, Indonesia, Australia, China, Germany, France, Italy, Portugal, Bangladesh, etc. The products are offered as per required specifications and in correct shape and size in mm or meshs or microns as specified by the buyer. The participating units have one or more accreditations like FDA - cGMP and GLP approval, ISO-9001 Certified, "REACH" Registered, ISO-14001, ISO/IEC 17025, ISO-22000, FSSC 22000, ISO 45001, Kosher Certified, Halal Certified, HACCP, FSSAI. We offer Commercial Pure & IP BP EP Ph Eur USP NF JP FCC Food Grade Analytical Reagent Grades of Chemicals |
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Arginine or L-Arginine, low endotoxin, low metal: CAS Number: 74-79-3, EINECS EC Number: 200-811-1 or 230-571-3, Molecular Formula: H2NC(=NH)NH(CH2)3CH(NH2)CO2H or C6H14N4O2, Molecular Weight: 174.20, HS Code 2922.4990
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SDS MSDS Sheet of Arginine or L-Arginine, low endotoxin Manufacturers
Arginine, low endotoxin, low metal
L-Arginine Pure Suppliers
Arginine, also known as L-Arginine is an α-amino acid that is used in the biosynthesis of proteins. L-arginine is an amino acid that helps the body make proteins. It can be obtained naturally in the diet and is also found in dietary supplement form. Foods rich in L-arginine include plant and animal proteins, such as dairy products, meat, poultry, fish, and nuts.
General Properties and Specifications of L-Arginine, low endotoxin, low metal:
Appearance: White or almost white, crystalline powder or colourless crystals, hygroscopic.
Odor: Odorless
Assay: 99% minimum.
Melting point: 222C literature.
Solubility: It is soluble in water, insoluble in ether, and sparingly soluble in alcohol.
Storage: Store at 4C
Specifications of Arginine USP Grade:
C6H14N4O2 --- 174.20
L-Arginine --- [CAS 74-79-3].
DEFINITION
Arginine contains NLT 98.5% and NMT 101.5% of C6H14N4O2 , as l-arginine, calculated on the dried basis.
IDENTIFICATION
Infrared Absorption
ASSAY
To pass the test.
Acceptance criteria: 98.5%–101.5% on the dried basis
Residue on Ignition: NMT 0.3%
Chloride and Sulfate, Chloride: A 1.0-g portion shows no more chloride than corresponds to 0.70 mL of 0.020 N hydrochloric acid (0.05%).
Chloride and Sulfate, Sulfate: A 1.0-g portion shows no more sulfate than corresponds to 0.30 mL of 0.020 N sulfuric acid (0.03%).
Iron: NMT 30 ppm
Organic Impurities:
To pass the test.
Acceptance criteria
Individual impurities: Any secondary spot from the Sample solution is not larger or more intense than the principal spot from the Standard solution, NMT 0.5%
Total impurities: NMT 2.0%
Optical Rotation, Specific Rotation: +26.3° to +27.7°
Loss on Drying: Dry a sample at 105C for 3 h: it loses NMT 0.5% of its weight.
Packaging and Storage: Preserve in well-closed containers.
Specifications of Arginine BP Ph Eur Grade:
C6H14N4O2 --- 174.2 --- CAS 74-79-3
Action and use: Amino acid; nutrient.
DEFINITION
(2S)-2-Amino-5-guanidinopentanoic acid.
Product of fermentation or of protein hydrolysis.
Content: 98.5 per cent to 101.0 per cent (dried substance).
CHARACTERS
Appearance: White or almost white, crystalline powder or colourless crystals, hygroscopic.
Solubility: Freely soluble in water, very slightly soluble in ethanol (96 per cent).
IDENTIFICATION
First identification: A, C
Second identification: A, B, D, E
A. Specific optical rotation (see Tests).
B. Solution S (see Tests) is strongly alkaline.
C. Infrared absorption spectrophotometry.
Comparison arginine CRS.
If the spectra obtained show differences, dry the substance to be examined and the reference substance in an oven at 105C and record new spectra.
D. Thin-layer chromatography:
To pass the test.
Results The principal spot in the chromatogram obtained with the test solution is similar in position, colour and size to the principal spot in the chromatogram obtained with the reference solution.
E. Dissolve about 25 mg in 2 mL of water. Add 1 mL of α-naphthol solution and 2 mL of a mixture of equal volumes of strong sodium hypochlorite solution and water. A red colour develops.
TESTS
Solution S: Dissolve 2.5 g in distilled water and dilute to 50 mL with the same solvent.
Appearance of solution: Solution S is clear and not more intensely coloured than reference solution.
Specific optical rotation: + 25.5 to + 28.5 (dried substance).
Dissolve 2.00 g in hydrochloric acid and dilute to 25.0 mL with the same acid.
Ninhydrin-positive substances:
To pass the test.
Limits:
-any ninhydrin-positive substance: for each impurity, maximum 0.2 per cent;
-total: maximum 0.5 per cent;
-reporting threshold: 0.05 per cent.
Chlorides: Maximum 200 ppm.
Sulfates: Maximum 300 ppm.
Ammonium: To pass the test.
Iron: Maximum 10 ppm.
Loss on drying: Maximum 0.5 per cent, determined on 1.000 g by drying in an oven at 105C.
Sulfated ash: Maximum 0.1 per cent, determined on 1.0 g.
STORAGE
In an airtight container, protected from light.
IMPURITIES
Other detectable impurities (the following substances would, if present at a sufficient level, be detected by one or other of the tests in the monograph. They are limited by the general acceptance criterion for other/unspecified impurities. It is therefore not necessary to identify these impurities for demonstration of compliance.
: A, B, C.
A. (2S)-2,6-diaminohexanoic acid (lysine),
B. (2S)-2-amino-5-(carbamoylamino)pentanoic acid (citrulline),
C. (2S)-2,5-diaminopentanoic acid (ornithine).
Specifications of L-Arginine FCC Food Grade:
L-2-Amino-5-guanidinovaleric Acid
C6H14N4O2 Formula wt 174.20
CAS: [74-79-3]
DESCRIPTION
L-Arginine occurs as white crystals or as a white crystalline powder. It is soluble in water, insoluble in ether, and sparingly soluble in alcohol. It is strongly alkaline, and its water solutions absorb carbon dioxide from the air.
Function: Nutrient.
Identification: The infrared absorption spectrum of the sample exhibits relative maxima at the same wavelengths as those of a typical spectrum as shown in the section on Infrared Spectra, using the same test conditions as specified therein.
Assay: Not less than 98.5% and not more than 101.5% of C6H14N4O2, calculated on the dried basis.
Lead: Not more than 5 mg/kg.
Loss on Drying: Not more than 1.0%.
Optical (Specific) Rotation: [α]D20°: Between +26.0° and +27.9°, calculated on the dried basis; or [α]D25°: Between +25.8° and +27.7°, calculated on the dried basis.
Residue on Ignition: Not more than 0.2%.
For Original Monographs of IP Indian Pharmacopoeia BP British Pharmacopoeia USP US Pharmacopoeia FCC Food Grade product, please check with the respective web-pages or books.
We also manufacture and supply as under:
L- Arginine ALPHA- Ketoglutarate 2:1
L-Arginine Hydrochloride or L-Arginine HCl
Manufacturers:
MUBY CHEMICALS
Ambernath Mumbai, Ankleshwar Gujarat, India
TEL: (OFFICE) +912223770100, +912223726950
Current Date Time in India GMT+5:30
e-mail: info@mubychem.com
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Last
21 June, 2024
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Arginine or L-Arginine SDS Sheet, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet 24-Oct-20
1. Product Identification
Product Name & Other Names: Arginine or L-Arginine.
CAS No.: 74-79-3
EINECS EC Code: 200-811-1 or 230-571-3
Molecular Weight: 174.20
Chemical Formula: H2NC(=NH)NH(CH2)3CH(NH2)CO2H or C6H14N4O2
Relevant uses and uses advised against (if any): Industrial Manufacturing.
SUPPLIER: As per letterhead.
2. Hazards Identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008
Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
This substance is not classified as dangerous according to Directive 67/548/EEC.
Labeling according to GHS & Regulation (EC) No 1272/2008
GHS Label Elements NONE |
Signal Words: None
Hazards not otherwise classified (HNOC):
May cause mild skin irritation.
May cause mild eye irritation.
May cause mild respiratory irritation.
Precautionary statements:
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P262: Do not get in eyes, on skin, or on clothing.
P281: Use personal protective equipment as required.
P302+P352: IF ON SKIN: Wash with plenty of soap and water.
P303+P361+P353: IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+313: If eye irritation persists get medical advice/attention.
3. Composition/Information on Ingredients
Product Name & Other Names: Arginine or L-Arginine.
CAS No.: 74-79-3
EINECS EC Code: 200-811-1 or 230-571-3
4. First Aid Measures
Always seek medical advice after the first aid treatment.
Inhalation: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.
Ingestion: Contact medical center quickly. Never give anything by mouth to an unconscious person. Get medical attention.
Skin Contact: Immediately flush skin with plenty of water for at least 15 minutes. Remove contaminated clothing and shoes. Get medical attention. Wash clothing before reuse. Thoroughly clean shoes before reuse.
Eye Contact: Check for and remove any contact lenses. Immediately flush eyes with running water for at least 15 minutes, keeping eyelids open. Cold water may be used. Get medical attention.
5. Fire Fighting Measures
Combustible at high temperature. High heat or direct flame is necessary to cause ignition. Toxic fumes, carbon monoxide and nitrogen oxides may be formed in fire.
Explosion: at high temperature, explosive vapor-air mixtures may be formed.
Fire Extinguishing Media: Dry chemical, foam, water spray or carbon dioxide. Do not use a solid stream of water, since the stream will scatter and spread the fire. Water spray may be used to keep fire exposed containers cool.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes. Fire-extinguishing work is done from the windward and the suitable fire-extinguishing method according to the surrounding situation is used. Uninvolved persons should evacuate to a safe place.
6. Accidental Release Measures
Personal precautions, protective equipment and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil or water sources.
Methods and materials used for containment Cleanup procedures and Storage:
Small Spill: Mop and pick up the material and place in an appropriate waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to local and regional authority requirements.
Large Spill: Avoid dust formation. Keep away from heat. Keep away from sources of ignition. Provide ventilation. Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g. sand, earth, diatomaceous earth, vermiculite). Vacuum or sweep-up and remove to an approved disposal container.
7. Handling and Storage
Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. Wash thoroughly after handling. Do not drink, eat or smoke while handling. Avoid contact with skin, eyes and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Keep away from heat and source of fire. Store in cold, dry and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Do not breathe dust. Do not leave the material container open. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like oxidizing material and acids. Store in light-resistant containers. Prevent any electrostatic discharge.
8. Exposure Controls/Personal Protection
Airborne Exposure Limits: This product does not contain any hazardous materials with occupational exposure limits established by the region-specific regulatory bodies.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area. Please refer to the ACGIH document, Industrial Ventilation, A Manual of Recommended Practices, most recent edition, for details.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to the substance is apparent and engineering controls are not feasible, consult an industrial hygienist. For emergencies, or instances where the exposure levels are not known, use a full-face piece positive-pressure, air-supplied respirator. WARNING: Air purifying respirators do not protect workers in oxygen-deficient atmospheres.
Skin Protection: Wear impervious protective clothing, including boots, gloves, lab coat, apron or coveralls, as appropriate, to prevent skin contact.
Eye Protection: Use chemical safety goggles and/or a full face shield where splashing is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Dust deposits on floors and other surfaces may pick up moisture and cause the surfaces to become slippery and present safety hazards. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.
9. Physical and Chemical Properties
Appearance: White or almost white, crystalline powder or colorless crystals, hygroscopic.
Odor: Odorless.
Odor threshold: Not available.
pH: 10.5 to 12 100 g/l at 20C.
Relative density: Not available.
Melting Point: 222C literature.
Initial boiling point and boiling range: Not available.
Flash point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility: It is soluble in water, insoluble in ether, and sparingly soluble in alcohol.
Viscosity: Not available.
Molecular Weight: 174.20
Chemical Formula: H2NC(=NH)NH(CH2)3CH(NH2)CO2H or C6H14N4O2.
10. Stability and Reactivity
Stability: Stable under ordinary conditions of use and storage.
Hazardous Decomposition Products: Carbon dioxide, carbon monoxide, nitrogen oxides and toxic fumes may form when heated to decomposition.
Hazardous Polymerization: Not reported. However, it can explode under certain conditions.
Incompatibilities: Acids, oxidizing agents, heat, and sparks.
Conditions to Avoid: Heat, flames, sunlight, ignition sources, moisture, and incompatibles.
11. Toxicological Information
Toxicity:
LD50 Oral - Rat - male and female: > 5.110 mg/kg.
Mutagenic Effects: No information available.
Reproductive Effects: No information available.
Carcinogenicity: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC, ACGIH, OSGHA or NTP.
12. Ecological Information
Toxicity to fish: semi-static test LC50 - Danio rerio (zebra fish) - 2.800 mg/l - 96 h.
Toxicity to daphnia and other aquatic invertebrates: static test EC50 Daphnia magna (Water flea): 1,800 mg/l; 24 h.
Biodegradability: Readily biodegradable
Mobility in soil: Likely to be mobile.
Results of PBT and vPvB assessment: Not available.
13. Disposal Considerations
Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. Processing use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose of container and unused contents in accordance with federal, state and local requirements.
14. Transport Information
DOT USA, TDG Canada & ADR/RID Europe: Not regulated
IMDG/IMO: Not regulated
IATA: Not regulated.
15. Regulatory Information
USA:
SARA 302: Not subject to the reporting requirements of SARA Title III, Section 302.
SARA 313: This material does not contain any chemical components with known CAS numbers that exceed the threshold (De Minimis) reporting levels established by SARA Title III, Section 313.
SARA 311/312 Hazards: No.
California Prop. 65 Components: This product does not contain any chemicals known to State of California to cause cancer, birth defects, or any other reproductive harm.
Disclaimer:
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Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
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