L-Glutamine or L-Glutamic Acid-5-amide USP and FCC Food Grade Grade Manufacturers, with SDS GHS MSDS Sheet

Supplier, Manufacturer, Exporter of L-Glutamine or L-Glutamic Acid-5-amide, Muby Chemicals of Mubychem Group, established in 1976, is the original manufacturers of Specialty Chemicals, Pharmaceutical Excipient, Fragrance Food & Flavor chemicals, Reagent Grade Chemicals, Shale Gas Fracturing Chemicals in India. Mubychem Group has several manufacturing facilities spread across Western India and world wide contacts and toll manufacturers. We are exporting globally to countries like USA, Canada, Europe, UAE, South Africa, Tanzania, Kenya, Egypt, Nigeria, Cameroon, Uganda, Turkey, Mexico, Brazil, Chile, Argentina, Dubai, Korea, Vietnam, Thailand, Malaysia, Indonesia, Australia, China, Germany, France, Italy, Portugal, Bangladesh, etc.

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L-Glutamine or L-Glutamic Acid-5-amide CAS Number 56-85-9, EINECS EC Number: 200-292-1, Molecular Formula: C5H10N2O3, Molecular Weight: 146.14, HS Code 29224990 or 29241900

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Specifications, Safety Data Sheet, Manufacturing process details, Wholesale retail buy sell prices, Uses etc available on line in these pages for L-Glutamine or L-Glutamic Acid-5-amide.

For SDS MSDS Sheet Click
SDS MSDS Sheet of L-Glutamine or L-Glutamic Acid-5-amide Manufacturers

USP and FCC Food Grade L-Glutamic Acid-5-amide Suppliers

General Properties and Specifications of L-Glutamine or L-Glutamic Acid-5-amide:
Appearance: White crystalline powder.
Solubility of 10% solution 2N HCl: Clear colorless.
Assay: 99% minimum.
Specific rotation [α]: +31.5° to +32.5° (C=2 , N HCl).
Loss on drying: 0.5% maximum.
Sulfated Ash: max. 0.1% maximum.
Chloride (CI): 0.01% maximum.
Sulphate (SO4): 0.01% maximum.
Iron (Fe): 0.001% maximum.
Heavy Metals (Pb): 0.001% maximum.
Ammonium (NH4): 0.01% maximum.
Homogeneity by TLC: Passes test.
Suitability for Cell Culture: Passes test.
Bacterial Endotoxin Test (BET) (EU/mg = IU/mg) <0.05 EU/mg.
pH: 5.0 - 6 (14.6 g/l in water @ 25C.
Relative Density: 1.47 @ 20C.
Melting Point: 185C-186C.
Boiling Point: 446C Predicted.
Solubility: Soluble in water.
Storage: Room temperature.

Glutamine USP Grade Specifications:
C5H10N2O3 --- 146.14
2-Aminoglutaramic acid 56-85-9
UNII: 0RH81L854J

Glutamine contains NLT 98.5% and NMT 101.5% of l-glutamine (C5H10N2O3), calculated on the dried basis.

A. Infrared Absorption

Residue on Ignition: NMT 0.3%
Chloride and Sulfate, Chloride: NMT 0.05%
Chloride and Sulfate, Sulfate: NMT 0.03%
Iron: NMT 30 ppm.
Related Compounds: To pass the test.
Optical Rotation, Specific Rotation: 40 mg/mL in water. Warm at 40C to dissolve. Acceptance criteria: +6.3° to +7.3°
Loss on Drying: Dry a sample at 105° for 3 h: it loses NMT 0.3% of its weight.

L-Glutamine FCC Food Grade Specifications:
L-2-Aminoglutaramic Acid
C5H10N2O3 Formula weight 146.15
CAS 56-85-9

Glutamine contains NLT 98.5% and NMT 101.5% of l-glutamine (C5H10N2O3), calculated on the dried basis.

Infrared Absorption

L-Glutamine occurs as white crystals or a crystalline powder. It is soluble in water and practically insoluble in alcohol and in ether. Its solutions are acid to litmus. It melts with decomposition at about 185C.
Function: Nutrient.

Identification: The infrared absorption spectrum of the sample exhibits maxima only at the same wavelengths as those of a typical spectrum as shown in the section on Infrared Spectra, using the same conditions as specified therein.
Assay: Not less than 98.5% and not more than 101.5% of C5H10N2O3, calculated on the dried basis.
Lead: Not more than 5 mg/kg.
Loss on Drying: Not more than 0.3%.
Optical (Specific) Rotation [α]D20°: Between +6.3° and +7.3°, calculated on the dried basis.
Residue on Ignition Not more than 0.1%.

For Original Monographs of IP Indian Pharmacopoeia BP British Pharmacopoeia USP US Pharmacopoeia FCC Food Grade product, please check with the respective web-pages or books.

We also manufacture and supply as under:

Calcium Alpha Ketoglutarate

Glutathione Reduced

Glutaric Anhydride

L-Glutamic Acid

Magnesium Alpha Ketoglutarate

Magnesium Glutamate

Monosodium Glutamate

Tetrasodium Glutamate Diacetate


L-Glutamine or L-Glutamic Acid-5-amide

Theanine or L-theanine or N-γ-Ethyl-L-glutamine or L-γ-Glutamylethylamide.


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Last 16 June, 2024

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L-Glutamine or L-Glutamic Acid-5-amide SDS Sheet, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet

1. Product Identification

Product Name & Other Names: L-Glutamine or L-Glutamic Acid-5-amide.
CAS No.: 56-85-9
EINECS EC Code: 200-292-1
Molecular Weight: 146.14
Chemical Formula: C5H10N2O3
Relevant uses and uses advised against (if any): Industrial Manufacturing.
SUPPLIER: As per letterhead.

2. Hazards Identification

GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008

Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
This substance is not classified as dangerous according to Directive 67/548/EEC.

Labeling according to GHS & Regulation (EC) No 1272/2008

GHS Label Elements

Signal Words: None

Hazards not otherwise classified (HNOC):
May cause mild skin irritation.
May cause mild eye irritation.
May cause mild respiratory irritation.

Precautionary statements:
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P262: Do not get in eyes, on skin, or on clothing.
P281: Use personal protective equipment as required.
P302+P352: IF ON SKIN: Wash with plenty of soap and water.
P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+313: If eye irritation persists get medical advice/attention.

3. Composition/Information on Ingredients

Product Name & Other Names: L-Glutamine or L-Glutamic Acid-5-amide.
CAS No.: 56-85-9
EINECS EC Code: 200-292-1

4. First Aid Measures

Always medical advice after the first aid treatment.

Inhalation: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.
Ingestion: Contact medical center quickly. Never give anything by mouth to an unconscious person. Get medical attention.
Skin Contact: Immediately flush skin with plenty of water for at least 15 minutes. Remove contaminated clothing and shoes. Get medical attention. Wash clothing before reuse. Thoroughly clean shoes before reuse.
Eye Contact: Check for and remove any contact lenses. Immediately flush your eyes with running water for at least 15 minutes, keeping eyelids open. Cold water may be used. Get medical attention.

5. Fire Fighting Measures

Combustible. High heat or direct flame is necessary to cause ignition. Toxic fumes and carbon monoxide and nitrogen oxides may be formed in fire.
Explosion: Above the flash point, explosive vapor-air mixtures may be formed.
Fire Extinguishing Media: Water spray, Dry chemical, foam, or carbon dioxide. Do not use a solid stream of water, as the stream will scatter and spread the fire. Water spray may be used to keep fire exposed containers cool. Suppress (knock down) gases/vapors/mists with a water spray jet.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes. Fire-extinguishing work is done from the windward and a suitable fire-extinguishing method according to the surrounding situation is used. Uninvolved persons should evacuate to a safe place.

6. Accidental Release Measures

Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment cleanup procedures and Storage:
Small Spill: Mop and pick up the material and place in an appropriate waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to local and regional authority requirements.
Large Spill: Avoid dust formation. Keep away from heat. Keep away from sources of ignition. Provide ventilation. Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g., sand, earth, diatomaceous earth, vermiculite). Vacuum or sweep-up and remove to an approved disposal container.

7. Handling and Storage

Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Keep away from heat and source of fire. Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Do not breathe dust. Do not leave the material container open. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store along with incompatible materials like oxidizing agents. Storage: Room temperature.

8. Exposure Controls/Personal Protection

Airborne Exposure Limits: Contains no substances with occupational exposure limit values.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area. Please refer to the ACGIH document, Industrial Ventilation, A Manual of Recommended Practices, most recent edition, for details.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to the substance is apparent and engineering controls are not feasible, consult an industrial hygienist. For emergencies, or instances where the exposure levels are not known, use a full-face piece positive-pressure, air-supplied respirator. WARNING: Air purifying respirators do not protect workers in oxygen-deficient atmospheres.
Skin Protection: Wear impervious protective clothing, including boots, gloves, lab coat, apron or coveralls, as appropriate, to prevent skin contact.
Eye Protection: Use chemical safety goggles and/or a full-face shield where splashing is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.

9. Physical and Chemical Properties

Appearance: White crystalline powder.
Odor: Not available.
Odor threshold: Not available.
pH: 5.0 - 6 (14.6 g/l in water @ 25C.
Relative density: about 1.47 @ 20C.
Melting Point: 185C-186C.
Initial boiling point and boiling range: 446C Predicted.
Flash point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility: Soluble in water.
Viscosity: Not available.
Molecular Weight: 146.14
Chemical Formula: C5H10N2O3

10. Stability and Reactivity

Stability: Stable under ordinary conditions of use and storage.
Hazardous Decomposition Products: Carbon dioxide, carbon monoxide, nitrogen oxides and toxic fumes may form when heated to decomposition.
Hazardous Polymerization: Not reported. However, it can explode under certain conditions.
Incompatibilities: oxidizing agents, heat, and sparks.
Conditions to Avoid: Heat, flames, ignition sources and incompatibles.

11. Toxicological Information

Oral - Rat LD50: >15000 mg/kg.
Mutagenic Effects: No information available.
Reproductive Effects: No information available.
Carcinogenicity: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible, or confirmed carcinogen by IARC, ACGIH, NTP or OSHA.

12. Ecological Information

Toxicity to daphnia and other aquatic invertebrates: semi-static test EC50 - Daphnia magna (Water flea) - > 100 mg/l - 48 h.
Biodegradability: No information available.
Mobility in soil: Likely to be mobile due to water solubility.
Persistence and degradability: Unlikely to persist due to water solubility.

13. Disposal Considerations

Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. Processing use or contamination of this product may change the waste management options. Dispose of containers and unused contents in accordance with federal, state, and local requirements.

14. Transport Information

DOT USA, TDG Canada & ADR/RID Europe: Not regulated.
IMDG/IMO & IATA/ICAO: Not regulated.

15. Regulatory Information

SARA 311/312
: See section 2.
USA California Proposition 65: No ingredient regulated by CA Prop 65 present.

16. Other Information

Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.