L-Glutamic Acid USP Dietary Supplement BP Ph Eur FCC Food Grade Manufacturers, with SDS GHS MSDS Sheet |
Supplier, Manufacturer, Exporter of L-Glutamic acid USP Dietary Supplement BP Ph Eur FCC Food Grade, Muby Chemicals of Mubychem Group, established in 1976, is the original manufacturers of Specialty Chemicals, Pharmaceutical Excipient, Fragrance Food & Flavor chemicals, Reagent Grade Chemicals, Shale Gas Fracturing Chemicals in India. Mubychem Group has several manufacturing facilities spread across Western India and world wide contacts and toll manufacturers. We are exporting globally to countries like USA, Canada, Europe, UAE, South Africa, Tanzania, Kenya, Egypt, Nigeria, Cameroon, Uganda, Turkey, Mexico, Brazil, Chile, Argentina, Dubai, Korea, Vietnam, Thailand, Malaysia, Indonesia, Australia, China, Germany, France, Italy, Portugal, Bangladesh, etc. The products are offered as per required specifications and in correct shape and size in mm or meshs or microns as specified by the buyer. The participating units have one or more accreditations like FDA - cGMP and GLP approval, ISO-9001 Certified, "REACH" Registered, ISO-14001, ISO/IEC 17025, ISO-22000, FSSC 22000, ISO 45001, Kosher Certified, Halal Certified, HACCP, FSSAI. We offer Commercial Pure & IP BP EP Ph Eur USP NF JP FCC Food Grade Analytical Reagent Grades of Chemicals |
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L-Glutamic acid: CAS Number: 56-86-0, EINECS EC Number: 200-293-7, Molecular Formula: HO2CCH2CH2CH(NH2)CO2H, Molecular Weight: 147.13, HS Code ---**
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SDS MSDS Sheet of L-Glutamic acid Manufacturers
L-Glutamic acid
USP Dietary Supplement BP Ph Eur FCC Food Grade Suppliers
Specifications of Glutamic Acid USP Dietary Supplement:
C5H9NO4 --- 147.13
l-Glutamic acid;
S-2-Aminopentanedioic acid --- CAS 56-86-0.
UNII: 3KX376GY7L
DEFINITION
Glutamic Acid contains NLT 98.5% and NMT 101.5% of l-glutamic acid (C5H9NO4), calculated on the dried basis.
IDENTIFICATION
Infrared Absorption 〈197K〉.
ASSAY
To pass the test.
Acceptance criteria: 98.5%–101.5% on the dried basis.
Residue on Ignition: NMT 0.1%.
Chloride and Sulfate, Chloride:
To pass the test.
Acceptance criteria: NMT 0.02%
Chloride and Sulfate, Sulfate:
To pass the test.
Acceptance criteria: NMT 0.02%
Iron: NMT 10 µg/g
Related Compounds:
To pass the test.
Acceptance criteria: Any secondary spot of the Sample solution is not larger or more intense than the principal spot of the Standard solution.
Individual impurities: NMT 0.5%
Total impurities: NMT 2.0%
Optical Rotation, Specific Rotation:
To pass the test.
Acceptance criteria: +31.5° to +32.5°
Loss on Drying: Dry a sample at 105C for 3 h: it loses NMT 0.1% of its weight.
Packaging and Storage: Preserve in well-closed containers, and store at controlled room temperature.
Specifications of Glutamic Acid BP Ph Eur Grade:
C5H9NO4 --- 147.1 --- 56-86-0
Action and use: Amino acid.
DEFINITION
Glutamic acid contains not less than 98.5 per cent and not more than the equivalent of 100.5 per cent of (2S)-2-aminopentanedioic acid, calculated with reference to the dried substance.
CHARACTERS
A white or almost white, crystalline powder or colourless crystals, freely soluble in boiling water, slightly soluble in cold water, practically insoluble in acetic acid, in acetone and in alcohol.
IDENTIFICATION
First identification: A, B
Second identification: A, C, D
A. Specific optical rotation.
B. Examine by infrared absorption spectrophotometry, comparing with the spectrum obtained with glutamic acid CRS. Examine the substances prepared as discs. If the spectra obtained show differences, dissolve the substance to be examined and the reference substance separately in the minimum quantity of water, evaporate to dryness at 60C and record new spectra using the residues.
C. Examine the chromatograms obtained in the test for ninhydrin-positive substances. The principal spot in the chromatogram obtained with test solution (b) is similar in position, colour and size to the principal spot in the chromatogram obtained with reference solution (a).
D. To 2.0 mL of solution S (see Tests) add 0.1 mL of phenolphthalein solution and 3.0 mL to 3.5 mL of1 M sodium hydroxide to change the colour of the indicator to red. Add a mixture of 3 mL of formaldehyde solution, 3 mL of carbon dioxide-free water and 0.1 mL of phenolphthalein solution, to which sufficient1 M sodium hydroxide has been added to produce a pink colour. The solution is decolourised. Add1 M sodium hydroxide until a red colour is produced. The total volume of 1 M sodium hydroxide used is 4.0 mL to 4.7 mL.
TESTS
Solution S: Dissolve 5.00 g in 1 M hydrochloric acid with gentle heating and dilute to 50.0 mL with the same acid.
Appearance of solution: Solution S is clear and colourless.
Specific optical rotation: + 30.5 to + 32.5, determined on solution S and calculated with reference to the dried substance.
Ninhydrin-positive substances: To pass the test.
Chlorides: Dissolve 0.25 g in 3 mL of dilute nitric acid and dilute to 15 mL with water. The solution, to which 1 mL of water is added instead of dilute nitric acid, complies with the limit test for chlorides (200 ppm).
Sulfates: Dilute 5 mL of solution S to 15 mL with distilled water. The solution complies with the limit test for sulfates (300 ppm).
Ammonium: 50 mg complies with limit test B for ammonium (200 ppm). Prepare the standard using 0.1 mL of ammonium standard solution (100 ppm NH4).
Iron: In a separating funnel, dissolve 1.0 g in 10 mL of dilute hydrochloric acid. Shake with 3 quantities, each of 10 mL, of methyl isobutyl ketone, shaking for 3 min each time. To the combined organic layers add 10 mL of water and shake for 3 min. The aqueous layer complies with the limit test for iron (10 ppm).
Loss on drying: Not more than 0.5 per cent, determined on 1.000 g by drying in an oven at 105C.
Sulfated ash: Not more than 0.1 per cent, determined on 1.0 g.
ASSAY
Dissolve 0.130 g in 50 mL of carbon dioxide-free water with gentle heating. Cool. Using 0.1 mL of bromothymol blue solution as indicator, titrate with 0.1 M sodium hydroxide until the colour changes from yellow to blue.
1 mL of 0.1 M sodium hydroxide is equivalent to 14.71 mg of C5H9NO4.
STORAGE
Protected from light.
Specifications of L-Glutamic Acid FCC Food Grade:
Glutamic Acid; L-2-Aminopentanedioic Acid
C5H9NO4 Formula weight 147.13
INS: 620 CAS: 56-86-0
DESCRIPTION
L-Glutamic Acid occurs as a white, free-flowing, crystalline powder. It is slightly soluble in water, forming acidic solutions. The pH of a saturated solution is about 3.2.
Function: Salt substitute; nutrient.
Identification: The infrared absorption spectrum of the sample exhibits relative maxima at the same wavelengths as those of a typical spectrum as shown in the section on Infrared Spectra, using the same test conditions as specified therein.
Assay: Not less than 98.5% and not more than 101.5% of C5H9NO4, calculated on the dried basis.
Lead: Not more than 5 mg/kg.
Loss on Drying: Not more than 0.1%.
Optical (Specific) Rotation: Between +31.5° and +32.5°, calculated on the dried basis.
Residue on Ignition: Not more than 0.3%.
For Original Monographs of IP Indian Pharmacopoeia BP British Pharmacopoeia USP US Pharmacopoeia FCC Food Grade product, please check with the respective web-pages or books.
We also manufacture and supply as under:
L-Glutamine or L-Glutamic Acid-5-amide
Theanine or L-theanine or N-γ-Ethyl-L-glutamine or L-γ-Glutamylethylamide.
Manufacturers:
MUBY CHEMICALS
Ambernath Mumbai, Ankleshwar Gujarat, India
TEL: (OFFICE) +912223770100, +912223726950
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e-mail: info@mubychem.com
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25 September, 2024
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L-Glutamic acid SDS Sheet, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet 24-Oct-20
1. Product Identification
Product Name & Other Names: L-Glutamic acid.
CAS No.: 56-86-0
EINECS EC Code: 200-293-7
Molecular Weight: 147.13
Chemical Formula: HO2CCH2CH2CH(NH2)CO2H
Relevant uses and uses advised against (if any): Industrial Manufacturing.
SUPPLIER: As per letterhead.
2. Hazards Identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008
Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
This substance is not classified as dangerous according to Directive 67/548/EEC.
Labeling according to GHS & Regulation (EC) No 1272/2008
GHS Label Elements NONE |
Signal Words: None
Hazards not otherwise classified (HNOC):
May cause mild skin irritation.
May cause mild eye irritation.
May cause mild respiratory irritation.
Precautionary statements:
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P262: Do not get in eyes, on skin, or on clothing.
P281: Use personal protective equipment as required.
P302+P352: IF ON SKIN: Wash with plenty of soap and water.
P303+P361+P353: IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+313: If eye irritation persists get medical advice/attention.
3. Composition/Information on Ingredients
Product Name & Other Names: L-Glutamic acid.
CAS No.: 56-86-0
EINECS EC Code: 200-293-7
4. First Aid Measures
Always seek medical advice after the first aid treatment.
Inhalation: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.
Ingestion: Contact medical center quickly. Never give anything by mouth to an unconscious person. Get medical attention.
Skin Contact: Immediately flush skin with plenty of water for at least 15 minutes. Remove contaminated clothing and shoes. Get medical attention. Wash clothing before reuse. Thoroughly clean shoes before reuse.
Eye Contact: Check for and remove any contact lenses. Immediately flush eyes with running water for at least 15 minutes, keeping eyelids open. Cold water may be used. Get medical attention.
5. Fire Fighting Measures
Combustible at high temperature. High heat or direct flame is necessary to cause ignition. Toxic fumes, carbon monoxide and nitrogen oxides may be formed in fire.
Explosion: at high temperature, explosive vapor-air mixtures may be formed.
Fire Extinguishing Media: Dry chemical, foam, water spray or carbon dioxide. Do not use a solid stream of water, since the stream will scatter and spread the fire. Water spray may be used to keep fire exposed containers cool.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes. Fire-extinguishing work is done from the windward and the suitable fire-extinguishing method according to the surrounding situation is used. Uninvolved persons should evacuate to a safe place.
6. Accidental Release Measures
Personal precautions, protective equipment and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil or water sources.
Methods and materials used for containment Cleanup procedures and Storage:
Small Spill: Mop and pick up the material and place in an appropriate waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to local and regional authority requirements.
Large Spill: Avoid dust formation. Keep away from heat. Keep away from sources of ignition. Provide ventilation. Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g. sand, earth, diatomaceous earth, vermiculite). Vacuum or sweep-up and remove to an approved disposal container.
7. Handling and Storage
Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. Wash thoroughly after handling. Do not drink, eat or smoke while handling. Avoid contact with skin, eyes and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Keep away from heat and source of fire. Store in cold, dry and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Do not breathe dust. Do not leave the material container open. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like oxidizing material and acids. Store in light-resistant containers. Prevent any electrostatic discharge.
8. Exposure Controls/Personal Protection
Airborne Exposure Limits: This product does not contain any hazardous materials with occupational exposure limits established by the region-specific regulatory bodies.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area. Please refer to the ACGIH document, Industrial Ventilation, A Manual of Recommended Practices, most recent edition, for details.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to the substance is apparent and engineering controls are not feasible, consult an industrial hygienist. For emergencies, or instances where the exposure levels are not known, use a full-face piece positive-pressure, air-supplied respirator. WARNING: Air purifying respirators do not protect workers in oxygen-deficient atmospheres.
Skin Protection: Wear impervious protective clothing, including boots, gloves, lab coat, apron or coveralls, as appropriate, to prevent skin contact.
Eye Protection: Use chemical safety goggles and/or a full face shield where splashing is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Dust deposits on floors and other surfaces may pick up moisture and cause the surfaces to become slippery and present safety hazards. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.
9. Physical and Chemical Properties
Appearance: White or almost white, crystalline powder or colorless crystals.
Odor: Not available.
Odor threshold: Not available.
pH: Not available.
Relative density: 1.54
Melting Point: 205C literature.
Initial boiling point and boiling range: Not available.
Flash point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility: Freely soluble in boiling water, slightly soluble in cold water, practically insoluble in acetic acid, in acetone and in alcohol.
Viscosity: Not available.
Molecular Weight: 147.13
Chemical Formula: HO2CCH2CH2CH(NH2)CO2H.
10. Stability and Reactivity
Stability: Stable under ordinary conditions of use and storage.
Hazardous Decomposition Products: Carbon dioxide, carbon monoxide, nitrogen oxides and toxic fumes may form when heated to decomposition.
Hazardous Polymerization: Not reported. However, it can explode under certain conditions.
Incompatibilities: Acids, oxidizing agents, heat and sparks.
Conditions to Avoid: Heat, flames, sunlight, ignition sources and incompatibles.
11. Toxicological Information
Toxicity:
LD50 Oral - Rat - male and female: > 5.110 mg/kg.
LD50 Dermal - Rat - male and female: > 2.000 mg/kg.
Mutagenic Effects: No information available.
Reproductive Effects: No information available.
Carcinogenicity: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC, ACGIH, OSGHA or NTP.
12. Ecological Information
Toxicity to fish: static test LC50 - Cyprinus carpio (Carp) - > 100 mg/l - 96 h.
Toxicity to daphnia and other aquatic invertebrates: static test EC50 - Daphnia magna (Water flea) - > 100 mg/l - 48 h.
Biodegradability: Readily biodegradable
Mobility in soil: Likely to be mobile.
Results of PBT and vPvB assessment: Not available.
13. Disposal Considerations
Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. Processing use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose of container and unused contents in accordance with federal, state and local requirements.
14. Transport Information
DOT USA, TDG Canada & ADR/RID Europe: Not regulated
IMDG/IMO: Not regulated
IATA: Not regulated.
15. Regulatory Information
USA:
SARA 302: Not subject to the reporting requirements of SARA Title III, Section 302.
SARA 313: This material does not contain any chemical components with known CAS numbers that exceed the threshold (De Minimis) reporting levels established by SARA Title III, Section 313.
SARA 311/312 Hazards: No.
California Prop. 65 Components: This product does not contain any chemicals known to State of California to cause cancer, birth defects, or any other reproductive harm.
Disclaimer:
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Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
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