Desvenlafaxine or o-Desmethylvenlafaxine USP NF Manufacturers, with SDS GHS MSDS Sheet

Supplier, Manufacturer, Exporter of Desvenlafaxine or o-Desmethylvenlafaxine USP NF, Muby Chemicals of Mubychem Group, established in 1976, is the original manufacturers of Specialty Chemicals, Pharmaceutical Excipient, Fragrance Food & Flavor chemicals, Reagent Grade Chemicals, Shale Gas Fracturing Chemicals in India. Mubychem Group has several manufacturing facilities spread across Western India and world wide contacts and toll manufacturers. We are exporting globally to countries like USA, Canada, Europe, UAE, South Africa, Tanzania, Kenya, Egypt, Nigeria, Cameroon, Uganda, Turkey, Mexico, Brazil, Chile, Argentina, Dubai, Korea, Vietnam, Thailand, Malaysia, Indonesia, Australia, China, Germany, France, Italy Portugal, Bangladesh, etc.

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Desvenlafaxine or o-Desmethylvenlafaxine CAS Number 93413-62-8, EINECS EC Number: yy, Molecular Formula: yy, Molecular Weight: yy, HS Code ---**

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SDS MSDS Sheet of Desvenlafaxine or o-Desmethylvenlafaxine Manufacturers

Desvenlafaxine
o-Desmethylvenlafaxine Suppliers
Desvenlafaxine

Desvenlafaxine USP NF Grade Specifications:
CHNO 263.38 4-[2-(Dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenol;
1-[2-(Dimethylamino)-1-(4-hydroxyphenyl)ethyl]cyclohexanol
CAS 93413-62-8
UNII: NG99554ANW.

DEFINITION
Desvenlafaxine contains NLT 98.0% and NMT 102.0% of desvenlafaxine (CHNO), calculated on the dried basis.

IDENTIFICATION
A
. SPECTROSCOPIC IDENTIFICATION TESTS, Infrared Spectroscopy
B. The retention time of the major peak of the Sample solution corresponds to that of the Standard solution, as obtained in the Assay.

Residue on Ignition: NMT 0.20%
Organic Impurities: To pass the test by chromatography.
Loss on Drying: Dry at 105C for 3 h. Acceptance criteria: NMT 0.50%
Packaging and Storage: Preserve in tight containers.

For Original Monographs of IP Indian Pharmacopoeia EP Ph Eur European Pharmacopoeia BP British Pharmacopoeia USP US Pharmacopoeia FCC Food Grade product, please check with the respective web-pages or books.

We also manufacture and supply as under:

Desvenlafaxine

Desvenlafaxine Succinate Monohydrate Anhydrous

Felodipine

Minoxidil

Pyridoxine Hydrochloride.

Manufacturers:

MUBY CHEMICALS
Ambernath Mumbai, Ankleshwar Gujarat, India
TEL: (OFFICE) +912223770100, +912223726950
Current Date Time in India GMT+5:30

e-mail: info@mubychem.com

USA, Canada, Mexico and other American
neighbouring buyers may
e-mail: us@mubychem.com
Call toll-free 1-877-682-9243 (1-877-MUBYCHEM)

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Last 26 November, 2024

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Desvenlafaxine or o-Desmethylvenlafaxine SDS, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet
03-Aug-24

1. Product Identification

Product Name & Other Names: Desvenlafaxine or o-Desmethylvenlafaxine.
CAS No.: 93413-62-8
EINECS EC Number: 700-516-2
Molecular Weight: 263.38
Chemical Formula: C16H25NO2
Relevant uses and uses advised against (if any): Industrial Manufacturing.
Suppliers: As per letterhead.

2. Hazards Identification

GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008

Serious eye damage/eye irritation Category 2A, H319

Labeling according to Regulation (EC) No 1272/2008

GHS Label Elements
Irritant
Irritant

Signal Words: Warning

Hazard statements:
H319: Causes serious eye irritation.

Precautionary statements:
P262: Do not get in eyes, on skin, or on clothing.
P264: Wash skin thoroughly after handling.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P270: Do not eat, drink or smoke when using this product.
P273: Avoid release to the environment.
P330: Rinse mouth.
P362: Take off contaminated clothing and wash before reuse.
P301+312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P332+313: If skin irritation occurs: Get medical advice/attention.
P302+P352: IF ON SKIN: Wash with plenty of soap and water.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P332+313: If skin irritation occurs: Get medical advice/attention.
P337+P313: If eye irritation persists: Get medical advice/ attention.
P501: Dispose of contents/container to authorized agents only.

Classification according to EU Directives 67/548/EEC or 1999/45/EC:
Hazard Symbols:
Xi Irritant.
Risk Phrases:
R36: Irritating to eyes.

3. Composition/Information on Ingredients

Product Name & Other Names: Desvenlafaxine or o-Desmethylvenlafaxine.
CAS No.: 93413-62-8
EINECS EC Number: 700-516-2

4. First Aid Measures

Inhalation: Remove to fresh air. Give oxygen if breathing is difficult; give artificial respiration if breathing has stopped. Keep person warm and quiet; get medical attention.
Ingestion: Induce vomiting immediately as directed by medical personnel. Never give anything by mouth to an unconscious person.
Skin Contact: Immediately flush skin with plenty of soap and water for at least 15 minutes. Remove contaminated clothing and shoes. Wash clothing before reuse. Thoroughly clean shoes before reuse. Get medical attention if irritation develops.
Eye Contact: Immediately flush eyes with plenty of water for at least 15 minutes, lifting upper and lower eyelids occasionally. Get medical attention.

5. Fire Fighting Measures

Fire: May become a fire hazard at high temperatures.
Fire Extinguishing Media: Use water spray, alcohol-resistant foam, dry chemical, or carbon dioxide. Avoid solid water jet.
Special hazards arising from the substance or mixture: Carbon oxides, Nitrogen oxides (NOx), Sulfur oxides, Hydrogen chloride gas.
Special Information In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes.

6. Accidental Release Measures

Personal precautions, protective equipment, and emergency procedures: Use personal protective equipment. Avoid dust formation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment cleanup procedures and Storage: Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g., sand, earth, diatomaceous earth, vermiculite). Vacuum or sweep-up and remove to an approved disposal container.

7. Handling and Storage

Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Do not leave the material container open. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like strong oxidizing agents. Avoid dust formation and control ignition sources. Containers may be hazardous when empty. Storage: Room Temperature. Preferably refrigerate. Recommended in a cool and dark place, <15C. Short term shipping may be ambient.

8. Exposure Controls/Personal Protection

Airborne Exposure Limits: Contains no substances with occupational exposure limit values.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full-face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.

9. Physical and Chemical Properties

Appearance: White to off-white powder. Air Sensitive.
Odor: Not available.
Odor threshold: Not available.
pH: Not available.
Relative density: Not available.
Boiling Point: Not available.
Melting Point: 220C to 224C literature.
Flash point
: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility: Soluble in water.
Viscosity: Not available.
Molecular Weight: 263.38
Chemical Formula: C16H25NO2

10. Stability and Reactivity

Stability: Stable under recommended conditions of use and storage. Air Sensitive.
Hazardous Decomposition Products: Nitrogen sulfur & carbon oxides along with chlorine compounds.
Hazardous Polymerization: Will not occur.
Incompatibilities: Strong oxidizing agents.
Conditions to Avoid: Heat, flame, ignition sources, dusting, and incompatibles.

11. Toxicological Information

Acute toxicity estimate Oral - 2.501 mg/kg.
Carcinogenic Effects: Not a reported carcinogen by IARC, NTP, ACGIH, OSHA.
Mutagenic Effects: Not available.
Developmental Toxicity: Not available.
Reproductive Effects: No information available.

12. Ecological Information

Persistence and Degradability: No information available.
Persistence and Degradability: Unlikely to persist due to water solubility.
Mobility: Likely to be mobile due to water solubility.
Bioaccumulation/ Accumulation: No information available.
Results of PBT and vPvB assessment: No data available for assessment.

13. Disposal Considerations

Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. Processing use or contamination of this product may change the waste management options. Dispose of container and unused Methylene Blue in accordance with legal requirements.

14. Transport Information

DOT USA, TDG and ADR/RID Europe: Not regulated.
IATA and IMDG/IMO: Not regulated.

15. Regulatory Information

USA:
SARA 311/312 Hazardous Categorization
: Acute Health Hazard as per section 2.
California Proposition 65: This product does not contain any Proposition 65 chemicals.

16. Other Information

European Labeling in Accordance with EC Directives:
H319: Causes serious eye irritation.

Classification according to EU Directives 67/548/EEC or 1999/45/EC:
Hazard Symbols:
Xi Irritant.
Risk Phrases:
R36: Irritating to eyes.

Disclaimer:
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Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
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