Caffeine Citrate USP BP Ph Eur Grade Manufacturers, with SDS GHS MSDS Sheet |
Supplier, Manufacturer, Exporter of Caffeine Citrate, Muby Chemicals of Mubychem Group, established in 1976, is the original manufacturers of Specialty Chemicals, Pharmaceutical Excipient, Fragrance Food & Flavor chemicals, Reagent Grade Chemicals, Shale Gas Fracturing Chemicals in India. Mubychem Group has several manufacturing facilities spread across Western India and world wide contacts and toll manufacturers. We are exporting globally to countries like USA, Canada, Europe, UAE, South Africa, Tanzania, Kenya, Egypt, Nigeria, Cameroon, Uganda, Turkey, Mexico, Brazil, Chile, Argentina, Dubai, Korea, Vietnam, Thailand, Malaysia, Indonesia, Australia, China, Germany, France, Italy, Bangladesh, Portugal, Bangladesh, etc. The products are offered as per required specifications and in correct shape and size in mm or meshs or microns as specified by the buyer. The participating units have one or more accreditations like FDA - cGMP and GLP approval, ISO-9001 Certified, "REACH" Registered, ISO-14001, ISO/IEC 17025, ISO-22000, FSSC 22000, ISO 45001, Kosher Certified, Halal Certified, HACCP, FSSAI. We offer Commercial Pure & IP BP EP Ph Eur USP NF JP FCC Food Grade Analytical Reagent Grades of Chemicals |
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Caffeine Citrate CAS Number 69-22-7, EINECS EC Number: 614-938-9, Molecular Formula: C8H10N4O2-C6H8O7 or C14H18N4O9, Molecular Weight: 386.32, HS Code 29393000
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SDS MSDS Sheet of Caffeine Citrate Manufacturers
Caffeine Citrate
USP BP Ph Eur Grade Suppliers
General Properties and Specifications of Caffeine Citrate:
Appearance: White crystalline powder.
Solubility: Soluble in water
Identification:
(A) the principal peak in the chromatogram obtained with the test solution corresponds to the principal peak in the chromatogram obtained with reference solution.
(B) Yields the reaction characteristic of citrates,
Heavy metal: Less than 15 ppm.
Radially carburizable Substances: Any colour produced is not more intense than that of a mixture of 1.0 ml of CCS and 9.0mI of FCS.
Sulphated Ash: Not more than 0.1%
LOD at 105C for 3 h.: Not more than 5.0%
Assay:
(A) Anhydrous Caffeine content: 48.0% to 52.0% w/w.
(B) Anhydrous Citric acid: 48.0% to 52.0%w/w.
(C) Sum total of above percentage: 98.5% to 101.0% w/w.
Storage: Room temperature.
Caffeine Citrate Oral Solution USP Grade Specifications:
DEFINITION
Caffeine Citrate Oral Solution is a sterile aqueous solution containing Caffeine and citric acid. It contains NLT 90.0% and NMT 110.0% of the labeled amount of caffeine citrate (C14H18N4O9). It contains no bacteriostat or other preservative.
IDENTIFICATION
A. The retention time of the major peak of the Sample solution corresponds to that of the Standard solution, as obtained.
B. Identification Tests—General, Citrate: Meets the requirements.
C.
Solution A: Transfer 4 g of potassium iodide to a 100-mL volumetric flask and add 10 mL of water. Shake until the potassium iodide is dissolved. Add 2 g of iodine to the volumetric flask and shake until dissolved. Dilute with water to volume.
Sample solution: 5.0 mL of Oral Solution
Analysis: Transfer the Sample solution to a 25-mL centrifuge tube, and add 5 drops of Solution A. Add 0.5 mL of 2.0 M hydrochloric acid.
Acceptance criteria: A brown precipitate that dissolves on neutralization with 0.5 mL of sodium hydroxide TS is produced.
Organic Impurities: To pass the test.
Sterility Test: To pass the test.
pH: 4.2–5.2
Packaging and Storage: Preserve in single-dose, tight containers, and store at a temperature between 15C –30C.
Caffeine Citrate Oral Solution BP Ph Eur Grade:
Action and use: Respiratory and central nervous system stimulant.
DEFINITION
Caffeine Citrate Oral Solution is a solution of caffeine citrate, prepared by the interaction of Caffeine and Citric Acid Monohydrate, in a suitable aqueous vehicle. Sodium citrate may also be present.
The oral solution complies with the requirements stated under Oral Liquids and with the following requirements.
Content of caffeine citrate, C8H10N4O2,C6H8O7: 95.0 to 105.0% of the stated amount.
IDENTIFICATION
A & B. To pass the Chromatographic test.
C. Yields the reaction characteristic of citrates.
For Original Monographs of IP Indian Pharmacopoeia EP Ph Eur European Pharmacopoeia BP British Pharmacopoeia USP US Pharmacopoeia FCC Food Grade product, please check with the respective web-pages or books.
We also manufacture and supply as under:
Manufacturers:
MUBY CHEMICALS
Ambernath Mumbai, Ankleshwar Gujarat, India
TEL: (OFFICE) +912223770100, +912223726950
Current Date Time in India GMT+5:30
e-mail: info@mubychem.com
USA, Canada, Mexico and other American
neighbouring buyers may
e-mail: us@mubychem.com
Call toll-free 1-877-682-9243 (1-877-MUBYCHEM)
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Last
15 April, 2024
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Caffeine Citrate SDS, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet 14-Apr-24
1. Product Identification
Product Name & Other Names: Caffeine Citrate.
CAS No.: 69-22-7
EINECS EC Number: 614-938-9
Molecular Weight: 386.32
Chemical Formula: C8H10N4O2-C6H8O7 or C14H18N4O9
Relevant uses and uses advised against (if any): Industrial Manufacturing.
Suppliers: As per letterhead.
2. Hazards Identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008
Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
This substance is not classified as dangerous according to Directive 67/548/EEC.
Labeling according to GHS & Regulation (EC) No 1272/2008
GHS Label Elements NONE |
Signal Word: None
Hazards not otherwise classified (HNOC):
May causes mild skin irritation.
May causes mild eye irritation.
Precautionary statements:
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P262: Do not get in eyes, on skin, or on clothing.
P281: Use personal protective equipment as required.
P302+P352 - IF ON SKIN: Wash with plenty of soap and water.
P303+P361+P353 - IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
3. Composition/Information on Ingredients
Product Name & Other Names: Caffeine Citrate.
CAS No.: 69-22-7
EINECS EC Number: 614-938-9
4. First Aid Measures
Always seek medical attention after first aid measures are provided.
Inhalation: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.
Ingestion: If swallowed, DO NOT INDUCE VOMITING. Give large quantities of water. Never give anything by mouth to an unconscious person. Get medical attention immediately.
Skin Contact: Wipe off excess material from skin then immediately flush skin with plenty of water for at least 15 minutes. Remove contaminated clothing and shoes. Get medical attention. Wash clothing before reuse. Thoroughly clean shoes before reuse.
Eye Contact: Check for and remove any contact lenses. In case of contact, immediately flush your eyes with plenty of water for at least 15 minutes. Cold water may be used. Get medical attention.
5. Fire Fighting Measures
Flammability of the Product: Non-flammable.
Products of Combustion: Fumes, Carbon oxides (CO CO2) and Nitrogen Oxides (NOx).
Fire Extinguishing Media: Water spray, dry chemical, alcohol foam, or carbon dioxide.
Special Information In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes.
6. Accidental Release Measures
Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment cleanup procedures and Storage: Do not inhale dust, vapors, mist, or gas. Avoid dust formation. Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g., sand, earth, diatomaceous earth, vermiculite). Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and allow to evacuate as per law.
7. Handling and Storage
Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. In case of insufficient ventilation, wear suitable respiratory equipment. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like strong oxidizing agents. Storage: Room temperature.
8. Exposure Controls/Personal Protection
Airborne Exposure Limits: Not established
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures below the Airborne Exposure Limits. Local exhaust ventilation is preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area. Please refer to the ACGIH document, Industrial Ventilation, A Manual of Recommended Practices, most recent edition, for details.
Personal Respirators (NIOSH Approved): If the exposure limit of is exceeded, a half-face dust/mist respirator may be worn for up to ten times the exposure limit or the maximum use concentration specified by the appropriate regulatory agency or respirator supplier, whichever is lowest. A full-face piece dust/mist respirator may be worn up to 50 times the exposure limit, or the maximum use concentration specified by the appropriate regulatory agency, or respirator supplier, whichever is lowest. For emergencies or instances where the exposure levels are not known, use a full-face piece positive-pressure, air-supplied respirator. WARNING: Air-purifying respirators do not protect workers in oxygen-deficient atmospheres.
Skin Protection: Wear impervious protective clothing, including boots, gloves, lab coat, apron or coveralls, as appropriate, to prevent skin contact.
Eye Protection: Use chemical safety goggles and/or full-face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.
9. Physical and Chemical Properties
Appearance: White crystalline powder..
Odor: Not available.
Odor threshold: Not available.
pH: Not available.
Relative density: Not available.
Melting point/freezing point: Not available.
Boiling Point: Not available.
Flash point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility: Not available.
Viscosity: Not available.
Molecular Weight: 386.32
Chemical Formula: C8H10N4O2-C6H8O7 or C14H18N4O9
10. Stability and Reactivity
Stability: Stable under ordinary conditions of use and storage.
Hazardous Decomposition Products: Toxic oxides of nitrogen, carbon oxide and fumes may form at elevated temperatures.
Hazardous Polymerization: Will not occur.
Incompatibilities: Strong oxidizing agents.
Conditions to Avoid: Moisture heat and incompatibles.
11. Toxicological Information
ORL-RAT LD50: Not available.
Carcinogenicity: No component of this product present at levels greater than or equal to 0.1% is identified as possible or confirmed human carcinogen by IARC, ACGIH, OSHA and NTP.
Teratogenic Effects: Not available.
Mutagenic Effects: Not available.
Developmental Toxicity: Not available.
Reproductive Effects: No information available.
12. Ecological Information
Toxicity to daphnia and other aquatic invertebrates: Not available.
Persistence and Degradability: Unlikely to persist.
Mobility: Likely to be mobile.
Bioaccumulation/ Accumulation: No information available.
Results of PBT and vPvB assessment: No data available for assessment.
13. Disposal Considerations
Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. Processing use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose of containers and unused contents in accordance with federal, state, and local requirements.
14. Transport Information
DOT USA: Not regulated.
TDG: Not regulated.
IATA: Not regulated.
IMDG/IMO: Not regulated.
ADR/RID Europe: Not regulated.
15. Regulatory Information
USA
California Proposition 65: Not listed.
SARA 311/312 Hazards: None. See section 2.
Disclaimer:
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Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
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