L-Aspartic Acid USP NF BP Ph Eur FCC Food Grade Manufacturers, with SDS GHS MSDS Sheet

Supplier, Manufacturer, Exporter of L-Aspartic Acid, Muby Chemicals of Mubychem Group, established in 1976, is the original manufacturers of Specialty Chemicals, Pharmaceutical Excipient, Fragrance Food & Flavor chemicals, Reagent Grade Chemicals, Shale Gas Fracturing Chemicals in India. Mubychem Group has several manufacturing facilities spread across Western India and world wide contacts and toll manufacturers. We are exporting globally to countries like USA, Canada, Europe, UAE, South Africa, Tanzania, Kenya, Egypt, Nigeria, Cameroon, Uganda, Turkey, Mexico, Brazil, Chile, Argentina, Dubai, Korea, Vietnam, Thailand, Malaysia, Indonesia, Australia, China, Germany, France, Italy, Portugal, Bangladesh, etc.

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L-Aspartic Acid: CAS Number: 56-84-8 for L-isomer and 1783-96-6 for D-isomer, EINECS EC Number: 200-291-6, Molecular Formula: HO2CCH2CH(NH2)CO2H or C4H7NO4, Molecular Weight: 133.10, HS Code 2922 49 85

Specifications, Safety Data Sheet, Manufacturing process details, Wholesale retail buy sell prices, Uses etc available on line in these pages for D-Aspartic Acid and L-Aspartic Acid.

L-Aspartic acid can refer to either enantiomer or a mixture of two forms or enantiomers of aspartic acid D- Aspartic acid and L- Aspartic acid. Of these two forms, only one, "L-aspartic acid", is directly incorporated into proteins. Other names of L-Aspartic acid are L-Aminosuccinic acid, 2-Aminobutanedioic acid.

General Properties and Specifications of L-Aspartic acid or L-Aminosuccinic acid, 2-Aminobutanedioic acid:
Appearance: White crystalline powder.
Assay: 99%
Heavy Metals: 10 ppm maximum.
Iron (Fe): 10 ppm
Loss on Drying: 0.2% ppm maximum.
Residue on Ignition: 0.1 % maximum.
Arsenic (As): 1 ppm maximum.
Relative density: about 1.7
Melting point: 270C literature.
Boiling point: 324C decomposes literature.
Solubility: Slightly soluble in water. Insoluble in ethanol.

Aspartic acid USP Grade Specifications:
C4H7NO4 --- 133.10
l-Aspartic acid --- CAS 56-84-8.

DEFINITION
Aspartic Acid contains NLT 98.5% and NMT 101.5% of aspartic acid (C4H7NO4), calculated on the dried basis.

Residue on Ignition: NMT 0.1%
Chloride and Sulfate, Chloride:
Sample solution: Dissolve 0.7 g of Aspartic Acid in 10 mL of diluted nitric acid, and dilute with water to 15 mL.
Acceptance criteria: The Sample solution shows no more chloride than corresponds to 0.20 mL of 0.020 N hydrochloric acid (NMT 0.02%).
Chloride and Sulfate, Sulfate:
Sample solution: Dissolve 0.8 g of Aspartic Acid in 4 mL of hydrochloric acid, and dilute with water to 15 mL.
Acceptance criteria: The Sample solution shows no more sulfate than corresponds to 0.25 mL of 0.020 N sulfuric acid (NMT 0.03%).
Iron: NMT 10 ppm
Related Compounds: To pass the chromatography test.
Optical Rotation, Specific Rotation:
Sample solution: 80 mg/mL in 6 N hydrochloric acid
Acceptance criteria: +24.0° to +26.0°, at 20°
Loss on Drying:
Analysis: Dry at 105C for 3 h.
Acceptance criteria: NMT 0.5%

Aspartic Acid BP Ph Eur Grade:
C4H7NO4 --- 133.1 --- CAS 56-84-8
Action and use: Amino acid.

DEFINITION
Aspartic acid contains not less than 98.5 per cent and not more than the equivalent of 101.5 per cent of (2S)-2-aminobutanedioic acid, calculated with reference to the dried substance.

CHARACTERS
A white or almost white, crystalline powder or colourless crystals, slightly soluble in water, practically insoluble in alcohol. It dissolves in dilute mineral acids and in dilute solutions of alkali hydroxides.

IDENTIFICATION
First identification: A, C
Second identification: A, B, D
A. Specific optical rotation.
B. A suspension of 1 g in 10 mL of water is strongly acid.
C. Examine by infrared absorption spectrophotometry.
D. Examine the chromatograms obtained in the test for ninhydrin-positive substances. The principal spot in the chromatogram obtained with test solution (b) is similar in position, colour and size to the principal spot in the chromatogram obtained with reference solution (a).

TESTS
Appearance of solution: Dissolve 0.5 g in 1 M hydrochloric acid and dilute to 10 mL with the same acid. The solution is clear and not more intensely coloured than reference solution.
Specific optical rotation: Dissolve 2.000 g in hydrochloric acid and dilute to 25.0 mL with the same acid. The specific optical rotation is + 24.0 to + 26.0, calculated with reference to the dried substance.
Ninhydrin-positive substances: To pass the chromatography test.
Ammonium: 50 mg complies with limit test B (200 ppm).
Iron: In a separating funnel, dissolve 1.0 g in 10 mL of dilute hydrochloric acid. Shake with 3 quantities, each of 10 mL of methyl isobutyl ketone, shaking for 3 min each time. To the combined organic layers add 10 mL of water and shake for 3 min. The aqueous layer complies with the limit test for iron (10 ppm).
Loss on drying: Not more than 0.5 per cent, determined on 1.000 g by drying in an oven at 105C.
Sulfated ash: Not more than 0.1 per cent, determined on 1.0 g.

ASSAY
Dissolve 0.100 g in 50 mL of carbon dioxide-free water, with slight heating if necessary. Cool and add 0.1 mL of bromothymol blue solution. Titrate with 0.1 M sodium hydroxide until the colour changes from yellow to blue.
1 mL of 0.1 M sodium hydroxide is equivalent to 13.31 mg of C4H7NO4.

L-Aspartic Acid FCC Food Grade:
L-Aminosuccinic Acid
C4H7NO4 Formula wt 133.10
CAS: [56-84-8]

DESCRIPTION
L-Aspartic Acid occurs as white crystals or as a crystalline powder. It is slightly soluble in water, but insoluble in alcohol and in ether. It melts at about 270C.
Function: Nutrient.

REQUIREMENTS
Identification: The infrared absorption spectrum.
Assay: Not less than 98.5% and not more than 101.5% of C4H7NO4, calculated on the dried basis.
Lead: Not more than 5 mg/kg.
Loss on Drying: Not more than 0.25%.
Optical (Specific) Rotation [alpha]D20°: Between +24.5° and +26.0°, calculated on the dried basis.
Residue on Ignition: Not more than 0.1%.

DL-Aspartic Acid FCC Food Grade:
DL-Aminosuccinic Acid
C4H7NO4 Formula wt 133.10
CAS: [617-45-8]

DESCRIPTION
DL-Aspartic Acid occurs as colorless or white crystals. It is slightly soluble in water, but insoluble in alcohol and in ether. It is optically inactive and melts with decomposition at about 280C.
Function: Nutrient.

For Original Monographs of IP Indian Pharmacopoeia BP British Pharmacopoeia USP US Pharmacopoeia FCC Food Grade product, please check with the respective web-pages or books.

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L-Aspartic acid or L-Aminosuccinic acid, 2-Aminobutanedioic acid SDS Sheet, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet 16-Jun-24

Product Name & Other Names: L-Aspartic acid or L-Aminosuccinic acid, 2-Aminobutanedioic acid.
CAS No.: 56-84-8 L-isomer and 1783-96-6 (D-isomer)
EINECS EC Code: 200-291-6
FEMA Number: 3656
Molecular Weight: 133.10
Chemical Formula: HO2CCH2CH(NH2)CO2H or C4H7NO4
Relevant uses and uses advised against (if any): Industrial Manufacturing.
SUPPLIER: As per letterhead.

GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008

Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
This substance is not classified as dangerous according to Directive 67/548/EEC.

Hazards not otherwise classified (HNOC):
May cause mild skin irritation.
May cause mild eye irritation.
May cause mild respiratory irritation.

Precautionary statements:
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P262: Do not get in eyes, on skin, or on clothing.
P281: Use personal protective equipment as required.
P302+P352: IF ON SKIN: Wash with plenty of soap and water.
P303+P361+P353 - IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+313: If eye irritation persists get medical advice/attention.

Product Name & Other Names: L-Aspartic acid or L-Aminosuccinic acid, 2-Aminobutanedioic acid.
CAS No.: 56-84-8 L-isomer and 1783-96-6 (D-isomer)
EINECS EC Code: 200-291-6
FEMA Number: 3656

Inhalation: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.
Ingestion: Contact medical center quickly. Never give anything by mouth to an unconscious person. Get medical attention.
Skin Contact: Immediately flush skin with plenty of water for at least 15 minutes. Remove contaminated clothing and shoes. Get medical attention. Wash clothing before reuse. Thoroughly clean shoes before reuse.
Eye Contact: Check for and remove any contact lenses. Immediately flush eyes with running water for at least 15 minutes, keeping eyelids open. Cold water may be used. Get medical attention.

Combustible. High heat or direct flame is necessary to cause ignition. Toxic fumes and carbon monoxide and nitrogen oxides may be formed in fire.
Explosion: Above the flash point, explosive vapor-air mixtures may be formed.
Fire Extinguishing Media: Dry chemical, foam, or carbon dioxide. Do not use a solid stream of water since the stream will scatter and spread the fire. Water spray may be used to keep fire exposed containers cool.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes. Fire-extinguishing work is done from the windward and the suitable fire-extinguishing method according to the surrounding situation is used. Uninvolved persons should evacuate to a safe place.

Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment Cleanup procedures and Storage:
Small Spill: Mop and pick up the material and place in an appropriate waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to local and regional authority requirements.
Large Spill: Avoid dust formation. Keep away from heat. Keep away from sources of ignition. Provide ventilation. Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g., sand, earth, diatomaceous earth, vermiculite). Vacuum or sweep-up and remove to an approved disposal container.

Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Keep away from heat and source of fire. Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Do not breathe dust. Do not leave the material container open. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like oxidizing material. Store in light-resistant containers. Prevent any electrostatic discharge.

Airborne Exposure Limits: Contains no substances with occupational exposure limit values.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area. Please refer to the ACGIH document, Industrial Ventilation, A Manual of Recommended Practices, most recent edition, for details.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to the substance is apparent and engineering controls are not feasible, consult an industrial hygienist. For emergencies, or instances where the exposure levels are not known, use a full-face piece positive-pressure, air-supplied respirator. WARNING: Air purifying respirators do not protect workers in oxygen-deficient atmospheres.
Skin Protection: Wear impervious protective clothing, including boots, gloves, lab coat, apron, or coveralls, as appropriate, to prevent skin contact.
Eye Protection: Use chemical safety goggles and/or a full-face shield where splashing is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.

Appearance: Almost white crystal or powder.
Odor: Not available.
Odor threshold: Not available.
pH: Not available.
Relative density: about 1.7
Melting Point: 270C literature.
Initial boiling point and boiling range: 324C decomposes literature.
Flash point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility: Soluble in water.
Viscosity: Not available.
Molecular Weight: 133.10
Chemical Formula: HO2CCH2CH(NH2)CO2H or C4H7NO4

Stability: Stable under ordinary conditions of use and storage.
Hazardous Decomposition Products: Carbon dioxide, carbon monoxide, nitrogen oxides and toxic fumes may form when heated to decomposition.
Hazardous Polymerization: Not reported. However, it can explode under certain conditions.
Incompatibilities: Acids, oxidizing agents, heat, and sparks.
Conditions to Avoid: Heat, flames, ignition sources and incompatibles.

Oral rat LD50 >2000 mg/kg.
Intraperitoneal mouse LD50 6 g/kg
Mutagenic Effects: NA.
Teratogenicity: No information available.
Reproductive Effects: No information available.
Carcinogenicity: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible, or confirmed human carcinogen by IARC, ACGIH, NTP or OSHA.

Toxicity to daphnia and other aquatic invertebrates: static test EC50 - Daphnia magna (Water flea) - 150 mg/l - 48 h.
Biodegradability: Readily biodegradable
Mobility in soil: Likely to be mobile due to water solubility.
Persistence and degradability: Unlikely to persist due to water solubility.
Results of PBT and vPvB assessment: Not available.

Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. Processing use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose of container and unused contents in accordance with federal, state, and local requirements.

DOT USA, TDG Canada & ADR/RID Europe: Not regulated.
IMDG/IMO: Not regulated.
IATA/ICAO: Not regulated.

Disclaimer:
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Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
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