Magnesium Aspartate BP n Pure Grade or Magnesium L-Hydrogen Aspartate or L-aspartic acid, magnesium salt Manufacturers, with SDS GHS MSDS Sheet
Supplier, Manufacturer, Exporter of Magnesium Aspartate, Muby Chemicals of Mubychem Group, established in 1976, is the original manufacturers of Specialty Chemicals, Pharmaceutical Excipient, Fragrance Food & Flavor chemicals, Reagent Grade Chemicals, Shale Gas Fracturing Chemicals in India. Mubychem Group has several manufacturing facilities spread across Western India and world wide contacts and toll manufacturers. We are exporting globally to countries like USA, Canada, Europe, UAE, South Africa, Tanzania, Kenya, Egypt, Nigeria, Cameroon, Uganda, Turkey, Mexico, Brazil, Chile, Argentina, Dubai, Korea, Vietnam, Thailand, Malaysia, Indonesia, Australia, China, Germany, France, Italy, Portugal, Bangladesh, etc.
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Magnesium Aspartate or Magnesium L-Hydrogen Aspartate or L-aspartic acid, magnesium salt : CAS Number: 72231-13-1 or 2068-80-6, EINECS EC Number: 218-191-6, Molecular Formula: C8H12MgN2O8,2H2O, Molecular Weight: 324.5 HS Code ---**
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SDS MSDS Sheet of Magnesium Aspartate ManufacturersMagnesium Aspartate
or Magnesium L-Hydrogen Aspartate or L-aspartic acid, magnesium salt Pure BP USP FCC Food Grade Suppliers
Magnesium aspartate or Magnesium L-Hydrogen Aspartate or L-aspartic acid, magnesium salt or magnesium (2S)-2-amino-4-hydroxy-4-oxobutanoate is White or almost white, crystalline powder or colourless crystals, the chelated magnesium salt of aspartic acid, it is a mineral supplement. It is freely soluble in water. It has increased bioavailability of magnesium compared to oxide and citrate.
Magnesium Aspartate BP Grade
Ph Eur
C8H12MgN2O8,2H2O -- 324.5 -- CAS 72231-13-1DEFINITION
Magnesium aspartate dihydrate contains not less than 98.0 per cent and not more than the equivalent of 102.0 per cent of magnesium di[(S)-2-aminohydrogenobutane-1,4-ioate], calculated with reference to the anhydrous substance.CHARACTERS
A white or almost white, crystalline powder or colourless crystals, freely soluble in water.IDENTIFICATION
A. It complies with the test for specific optical rotation (see Tests).
B. Examine the chromatograms obtained in the test for ninhydrin-positive substances. The principal spot in the chromatogram obtained with test solution (b) is similar in position, colour and size to the principal spot in the chromatogram obtained with reference solution (a).
C. Ignite about 15 mg until a white residue is obtained. Dissolve the residue in 1 ml of dilute hydrochloric acid, neutralise to red litmus paper by the addition of dilute sodium hydroxide solution and filter if necessary. The solution gives the reaction of magnesium.TESTS
Solution S: Dissolve 2.5 g in carbon dioxide-free water R prepared from distilled water and dilute to 100 ml with the same solvent.
Appearance of solution: Solution S is clear and colourless.
pH: The pH of solution S is 6.0 to 8.0.
Specific optical rotation: Dissolve 0.50 g in a 515 g/l solution of hydrochloric acid and dilute to 25.0 ml with the same acid. The specific optical rotation is + 20.5 to + 23.0, calculated with reference to the anhydrous substance.
Ninhydrin-positive substances: Examine by thin-layer chromatography, using a TLC silica gel plate.
Test solution (a): Dissolve 0.10 g of the substance to be examined in water and dilute to 10 ml with the same solvent.
Test solution (b): Dilute 1 ml of test solution (a) to 50 ml with water. Reference solution Dissolve 10 mg of magnesium aspartate dihydrate CRS in water and dilute to 50 ml with the same solvent.
Reference solution (b): Dilute 5 ml of test solution (b) to 20 ml with water.
Reference solution (c): Dissolve 10 mg of magnesium aspartate dihydrate CRS and 10 mg of glutamic acid CRS in 2 ml of water and dilute to 25 ml with the same solvent. Apply to the plate 5 μl of each solution. Allow the plate to dry in air. Develop over a path of 15 cm using a mixture of 20 volumes of glacial acetic acid, 20 volumes of water and 60 volumes of butanol. Allow the plate to dry in air and spray with ninhydrin solution. Heat at 100C to 105C for 15 min. Any spot in the chromatogram obtained with test solution (a), apart from the principal spot, is not more intense than the spot in the chromatogram obtained with reference solution (b) (0.5 per cent). The test is not valid unless the chromatogram obtained with reference solution (c) shows two clearly separated principal spots.
Chlorides: Dilute 10 ml of solution S to 15 ml with water R. The solution complies with the limit test for chlorides (200 ppm).
Sulphates: Dilute 12 ml of solution S to 15 ml with distilled water R. The solution complies with the limit test for sulphates (500 ppm). Carry out the evaluation of the test after 30 min.
Ammonium: 50 mg complies with limit test B for ammonium (200 ppm). Prepare the standard using 0.1 ml of ammonium standard solution (100 ppm NH4).
Iron: In a separating funnel, dissolve 0.20 g in 10 ml of dilute hydrochloric acid. Shake with three quantities, each of 10 ml, of methyl isobutyl ketone, shaking for 3 min each time. To the combined organic layers add 10 ml of water and shake for 3 min. The aqueous layer complies with the limit test for iron (50 ppm).
Heavy metals: Dissolve 2.0 g with gentle heating in 20 ml of water. 12 ml of the solution complies with limit test A for heavy metals (10 ppm). Prepare the standard using lead standard solution (1 ppm Pb).
Water: 10.0 per cent to 14.0 per cent, determined on 0.100 g by the semi-micro determination of water. Dissolve the substance in 10 ml of formamide at 50C protected from moisture, add 10 ml of anhydrous methanol and allow to cool. Carry out a blank determination.ASSAY
Dissolve 0.260 g in 10 ml of water and carry out the complexometric titration of magnesium.
1 ml of 0.1 M sodium edetate is equivalent to 28.85 mg of C8H12MgN2O8.IMPURITIES
Aspartic acid.For Original Monographs of IP Indian Pharmacopoeia BP British Pharmacopoeia USP US Pharmacopoeia FCC Food Grade product, please check with the respective web-pages or books.
We also manufacture and supply as under:
L-Asparagine Monohydrate or (S)-(+)-2-Aminosuccinamic acid
Chromium Ascorbate Aspartate Citrate
Manufacturers:
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Magnesium Aspartate SDS GHS, Safety Data Sheet<
MSDS Sheet, Material Safety Data Sheet 26-Oct-20Section 1: Chemical Product and Company Identification
Product Name & Other Names: Magnesium aspartate or Aspartic acid magnesium salt hydrate.
CAS Number: 72231-13-1
EINECS EC Code: 218-191-6 (to be checked)
Molecular Formula: C8H12MgN2O8,2H2O
Molecular Weight: 324.5
Relevant uses and uses advised against (if any) : Industrial Manufacturing.
Suppliers: As per letterhead.Section 2: Hazards Identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Hazard Class and Category Code(s), Regulation (EC) No 1272/2008 (CLP)Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
This substance is not classified as dangerous according to Directive 67/548/EEC.Labeling Regulation as per GHS & EC 1272/2008 (CLP) & GHS
GHS Label Elements
NONESignal Word: None
Hazards not otherwise classified (HNOC):
May causes mild skin irritation.
May causes mild eye irritation.Precautionary statements:
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P262: Do not get in eyes, on skin, or on clothing.
P281: Use personal protective equipment as required.
P302+P352 IF ON SKIN: Wash with plenty of soap and water.
P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+313: If eye irritation persists get medical advice/attention.Section 3: Composition and Information on Ingredients
Product Name & Other Names: Magnesium aspartate or Aspartic acid magnesium salt hydrate.
CAS Number: 72231-13-1
EINECS EC Code: 218-191-6 (to be checked).Section 4: First Aid Measures
Always seek medical advice after the first aid treatment.
Skin: Rinse with water. Soap may be used. Seek Medical Aid.
Eyes: Wash eyes with plenty of water for at least 15 minutes, lifting lids occasionally. Seek Medical Aid.
Inhalation: Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Ingestion: If swallowed, induce vomiting immediately after giving two glasses of water. Never give anything by mouth to an unconscious person.Section 5: Fire and Explosion Data
Flammability of the Product: Non-flammable.
Products of Combustion: Oxides of Carbon.
Fire Fighting Media and Instructions: Use water spray, alcohol-resistant foam, dry chemical, or carbon dioxide. Wear self-contained breathing apparatus for firefighting if necessary.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes. Fire-extinguishing work is done from the windward and the suitable fire-extinguishing method according to the surrounding situation is used. Uninvolved persons should evacuate to a safe place.Section 6: Accidental Release Measures
Personal precautions, protective equipment, and emergency procedures: Ventilate area of leak or spill. Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment Cleanup procedures and Storage:
Small Spill: Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to legal requirements.
Large Spill: Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g. sand, earth, diatomaceous earth, vermiculite). Vacuum or sweep-up and remove to an approved disposal container. Finish cleaning by spreading water on the contaminated surface and allow to evacuate as per law.Section 7: Handling and Storage
Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. In case of insufficient ventilation, wear suitable respiratory equipment. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like strong oxidizing agents and acids.Section 8: Exposure Controls/Personal Protection
Engineering Controls: Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits. If user operations generate dust, fume, or mist, use ventilation to keep exposure to airborne contaminants below the exposure limit.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Dust deposits on floors and other surfaces may pick up moisture and cause the surfaces to become slippery and present safety hazards. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.Section 9: Physical and Chemical Properties
Appearance: Solid white crystals powder or granules.
Odor: Slight.
Odor threshold: Not available.
pH (10% soln/water): about 6.
Relative density: Not available.
Melting point/freezing point: Decomposes at 140C
Initial boiling point and boiling range: Not available.
Flash point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility: Soluble in water.
Viscosity: Not available.
Molecular Formula: C8H12MgN2O8,2H2O
Molecular Weight: 324.5Section 10: Stability and Reactivity Data
Stability: It is stable in room temperature in closed containers under normal storage & handling.
Conditions of instability: Incompatible materials, Moisture
Incompatibility with various substances: Avoid high temperatures, sparks, open flames, and moisture. Avoid contact with strong oxidizing agents.
Polymerization: Will not occur.Section 11: Toxicological Information
No toxicological data available for this product. One report gives the following information:
Oral LD50> 5110 mg/kg (rat). The value refers to L-aspartic acid.
Carcinogenicity: No component of this product present at levels greater than or equal to 0.1% is identified as possible or confirmed human carcinogen by IARC, ACGIH, OSHA and NTP.
Mutagenic Effects: Not available.
Teratogenic Effects: Not available.
Developmental Toxicity: Not available.
Reproductive Effects: No information available.
The toxicological properties of this substance have not been fully investigated.Section 12: Ecological Information
Toxicity to fish: Not available.
Persistence and Degradability: No information available.
Mobility: No information available.
Bioaccumulation/ Accumulation: No information available.
Results of PBT and vPvB assessment: No data available for assessment.Section 13: Disposal Considerations
Waste Disposal: Waste must be disposed of in accordance with federal, state, and local environmental control regulations.
Section 14: Transport Information
DOT USA, TDG Canada & ADR/RID Europe: Not dangerous goods
IMDG/IMO: Not dangerous goods
IATA: Not dangerous goods.Section 15: Other Regulatory Information
USA Regulations:
Section 16 - Additional Information
No data available.DISCLAIMER: The information and recommendations set forth herein are presented in good faith and believed correct as of the date hereof. It is compiled from various sources and it is not necessarily all inclusive nor fully adequate in every circumstance. In addition, these suggestions should not be confused with nor followed in violation of applicable laws, regulations, rules or insurance requirements applicable. This MSDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. Individuals receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose.