Methylsulfonylmethane or Methyl sulfonyl methane MSM or Dimethyl sulfone DMSO2 Pure n USP Grade Manufacturers, with SDS GHS MSDS Sheet

Supplier, Manufacturer, Exporter of Methylsulfonylmethane or Dimethyl sulfone, Muby Chemicals of Mubychem Group, established in 1976, is the original manufacturers of Specialty Chemicals, Pharmaceutical Excipient, Fragrance Food & Flavor chemicals, Reagent Grade Chemicals, Shale Gas Fracturing Chemicals in India. Mubychem Group has several manufacturing facilities spread across Western India and world wide contacts and toll manufacturers. We are exporting globally to countries like USA, Canada, Europe, UAE, South Africa, Tanzania, Kenya, Egypt, Nigeria, Cameroon, Uganda, Turkey, Mexico, Brazil, Chile, Argentina, Dubai, Korea, Vietnam, Thailand, Malaysia, Indonesia, Australia, China, Germany, France, Italy, Portugal etc.

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Methylsulfonylmethane or Methyl sulfonyl methane MSM or Dimethyl sulfone DMSO2: CAS Number: 67-71-0, EINECS EC Number: 200-665-9, Molecular Formula: C2H6O2S or (CH3)2SO2, Molecular Weight: 94.13, HS Code ---**

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SDS MSDS Sheet of Methylsulfonylmethane or Methyl sulfonyl methane MSM or Dimethyl sulfone DMSO2 Manufacturers

Methylsulfonylmethane
Methyl sulfonyl methane MSM or Dimethyl sulfone DMSO2 USP Pure Suppliers
Methylsulfonylmethane Dimethyl sulfone

Methylsulfonylmethane (MSM) is a compound with the formula (CH3)2SO2. It is also known by several other names including methyl sulfone and dimethyl sulfone (DMSO2). It is considered relatively inert chemically. Because of its polarity and thermal stability, Methyl sulfonyl methane or Methylsulfonylmethane or Dimethyl sulfone is used industrially as a high-temperature solvent for both inorganic and organic substances. It is used as a medium in organic synthesis. It is recognized by U.S. FDA as generally recognized as safe (GRAS) substance. Methylsulfonylmethane (MSM) has become a popular dietary supplement used for a variety of purposes, including its most common use as an anti-inflammatory agent. It has been well-investigated in animal models, as well as in human clinical trials and experiments.

General Properties and Specifications of Methyl Sulfonyl Methane or Methylsulfonylmethane:
Appearance: White crystalline solid
Relative density: 1.45
Melting point: 109C literature.
Boiling point: 238C literature.
Turbidity of 10% solution in water: Clear and colorless.
Water Content: NMT 0.1%
Heavy Metals: NMT 3ppm.
Limit of dimethyl sulfoxide as an individual impurity: NMT 0.1%
Any other individual impurity: NMT 0.05%
Total impurities: NMT 0.2%
Total aerobic microbial count: NMT 1000cfu/g.
Yeast & Mold: NMT 100cfu/g.
E. Coli per 10g: Absent.


Specifications of Methylsulfonylmethane USP Dietary Suppliment Grade:
C2H6O2S -- 94.13
Dimethyl sulfone;
Sulfonylbismethane --- CAS 67-71-0.

DEFINITION
Methylsulfonylmethane contains NLT 98.0% and NMT 102.0% of methylsulfonylmethane (C2H6O2S), calculated on the anhydrous basis. The chromatographic purity is NLT 99.8%.

IDENTIFICATION
A. Infrared Absorption.
B.
The retention time of the major peak of the Sample solution corresponds to that of the Standard solution, as obtained in the Assay.
ASSAY
To pass the chromatographic test.
Acceptance criteria:  98.0%–102.0% on the anhydrous basis

TESTS
Chromatographic Purity and Limit of Dimethyl Sulfoxide
: To pass the test
Acceptance criteria:
Individual impurities:  NMT 0.1% of dimethyl sulfoxide; NMT 0.05% of any other individual impurity
Total impurities: NMT 0.2% for all impurities, including dimethyl sulfoxide
Melting Range or Temperature: 108.5C –110.5C
Microbial Enumeration Tests: The total aerobic microbial count is NMT 1000 cfu/g or mL, and the total combined molds and yeasts count is NMT 100 cfu/g or mL.
Absence of Specified Microorganisms: It meets the requirements for absence of Escherichia coli in 10 g.
Water Determination: NMT 0.1%. [Note— 500 mg of methylsulfonylmethane may be required for this analysis.

Packaging and Storage
Preserve in well-closed containers.

For Original Monographs of IP Indian Pharmacopoeia BP British Pharmacopoeia USP US Pharmacopoeia FCC Food Grade product, please check with the respective web-pages or books.

Manufacturers:

MUBY CHEMICALS
Ambernath Mumbai, Ankleshwar Gujarat, India
TEL: (OFFICE) +912223770100, +912223726950
Current Date Time in India GMT+5:30

e-mail: info@mubychem.com

USA, Canada, Mexico and other American
neighbouring buyers may
e-mail: us@mubychem.com
Call toll-free 1-844-682-9243 (1-844-MUBYCHEM)

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Last 27 August, 2022

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Methylsulfonylmethane or Methyl sulfonyl methane MSM or Dimethyl sulfone DMSO2 SDS, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet
 05-Nov-20

Section 1: Chemical Product and Company Identification

Product Name & Other Names: Methylsulfonylmethane or Methyl sulfonyl methane MSM or Dimethyl sulfone DMSO2
CAS Number
: 67-71-0
EINECS EC Number: 200-665-9
Molecular Formula: C2H6O2S or (CH3)2SO2
Molecular Weight: 94.13
Relevant uses and uses advised against (if any): Industrial use only.
Supplier: As per letterhead.

Section 2: Hazards Identification

GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008

Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
This substance is not classified as dangerous according to Directive 67/548/EEC.

Labeling according to GHS & Regulation (EC) No 1272/2008

GHS Label Elements
NONE

Signal Word: None

Hazards not otherwise classified (HNOC):
The toxicological properties of this material have not been fully investigated.
May causes mild skin irritation.
May causes mild eye irritation.
May cause irritation of digestive tract.
May cause irritation of respiratory tract.

Precautionary statements:
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P262: Do not get in eyes, on skin, or on clothing.
P281: Use personal protective equipment as required.
P302+P352 - IF ON SKIN: Wash with plenty of soap and water.
P303+P361+P353 - IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
P304 + P340 - IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+313: If eye irritation persists get medical advice/attention.

Section 3: Composition and Information on Ingredients

Product Name & Other Names: Methylsulfonylmethane or Methyl sulfonyl methane MSM or Dimethyl sulfone DMSO2
CAS Number
: 67-71-0
EINECS EC Number: 200-665-9

Section 4: First Aid Measures

Always seek medical advice after the first aid treatment.

Skin: Wash exposed area with soap and water.
Eyes: Wash eyes with plenty of water for at least 15 minutes, lifting lids occasionally. Seek Medical Aid.
Inhalation: Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Ingestion: If swallowed, induce vomiting immediately after giving two glasses of water. Never give anything by mouth to an unconscious person.

Section 5: Fire and Explosion Data

Flammability of the Product: Non-flammable.
Products of Combustion: Sodium oxide with oxides of sulfur, carbon and fumes.
Extinguisher Media: Use media suitable to extinguish surrounding fire. Use alcohol-resistant foam, dry chemical or carbon dioxide.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes. Fire-extinguishing work is done from the windward and the suitable fire-extinguishing method according to the surrounding situation is used. Uninvolved persons should evacuate to a safe place.

Section 6: Accidental Release Measures

Personal precautions, protective equipment and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil or water sources.
Methods and materials used for containment Cleanup procedures and Storage:
Small Spill: Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to legal requirements.
Large Spill: Contain spilled material. Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and allow to evacuate through the sanitary system.

Section 7: Handling and Storage

Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. Wash thoroughly after handling. Do not drink, eat or smoke while handling. Avoid contact with skin, eyes and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cool, dry and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Do not leave the material container open. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like incompatibles, oxidizing agents, acids. Keep in original containers and avoid contact with moisture.

Section 8: Exposure Controls/Personal Protection

Exposure Guidelines: Not established.
Engineering Controls: Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to airborne contaminants below the exposure limit.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Dust deposits on floors and other surfaces may pick up moisture and cause the surfaces to become slippery and present safety hazards. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.

Section 9: Physical and Chemical Properties

Physical state and appearance: White crystalline solid.
Odor: Not available.
Odor threshold: Not available.
pH: Not available.
Relative density: 1.45
Melting Point: 108.5C –110.5C.
Initial boiling point and boiling range: 238C.
Flash point: 143C.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility: Soluble in water.
Viscosity: Not available.

Section 10: Stability and Reactivity Data

Stability: Sodium Polystyrene Sulfonate is stable.
Conditions of Instability: Incompatible materials
Incompatibility with various substances: Oxidizing agents, Highly alkaline or acidic materials, Heat and Dust formation.
Corrosivity: Non-corrosive in presence of glass.
Hazardous Decomposition Products: Sodium oxide with oxides of sulfur, carbon and fumes.
Polymerization: Will not occur.

Section 11: Toxicological Information

Toxicity to Animals: LD50 Oral - Rat - > 5g/kg LD50 Dermal - Rabbit - > 5g/kg
Carcinogenicity: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC, NTP & ACGIH.
Mutagenic Effects: Not available.
Developmental Toxicity: Not available.
Reproductive Effects: No information available.

Section 12: Ecological Information

Ecotoxicity: The product is not expected to be harmful to marine life.
Persistence and Degradability: Soluble in water. Persistence is unlikely as per information available.
Mobility: Likely to be mobile due to water solubility.
Bioaccumulation/ Accumulation: No information available.
Results of PBT and vPvB assessment: No data available for assessment.
Products of Biodegradation: Possibly hazardous short-term degradation products are not likely. However, long term degradation products may arise.

Section 13: Disposal Considerations

Waste Disposal: Waste must be disposed of in accordance with federal, state and local environmental control regulations.

Section 14: Transport Information

DOT USA, TDG Canada & ADR/RID Europe: Not dangerous goods
IMDG/IMO: Not dangerous goods
IATA: Not dangerous goods.

Section 15: Other Regulatory Information

USA Regulations:
SARA 302: No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302.
SARA 313: This material does not contain any chemical components with known CAS numbers that exceed the threshold (De Minimis) reporting levels established by SARA Title III, Section 313.
California Prop. 65 Components: This product does not contain any chemicals known to State of California to cause cancer, birth defects, or any other reproductive harm.

Section 16 - Additional Information

Disclaimer:
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Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
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