Calcium Dobesilate Monohydrate BP Grade Manufacturers, with SDS GHS MSDS Sheet

Supplier, Manufacturer, Exporter of Calcium Dobesilate Monohydrate, Muby Chemicals of Mubychem Group, established in 1976, is the original manufacturers of Specialty Chemicals, Pharmaceutical Excipient, Fragrance Food & Flavor chemicals, Reagent Grade Chemicals, Shale Gas Fracturing Chemicals in India. Mubychem Group has several manufacturing facilities spread across Western India and world wide contacts and toll manufacturers. We are exporting globally to countries like USA, Canada, Europe, UAE, South Africa, Tanzania, Kenya, Egypt, Nigeria, Cameroon, Uganda, Turkey, Mexico, Brazil, Chile, Argentina, Dubai, Korea, Vietnam, Thailand, Malaysia, Indonesia, Australia, China, Germany, France, Italy, Portugal etc.

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Calcium Dobesilate Monohydrate: CAS Number: 20123-80-2, EINECS EC Number: 243-531-5, Molecular Formula: C12H10CaO10S2-H2O, Molecular Weight: 436.4, HS Code ---**

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SDS MSDS Sheet of Calcium Dobesilate Monohydrate BP Grade Manufacturers

Calcium Dobesilate Monohydrate
Pure BP Grade Suppliers
Calcium Dobesilate Monohydrate

Calcium Dobesilate Monohydrate BP
Ph. Eur.
C12H10CaO10S2,H2O --- 436.4 --- 20123-80-2

DEFINITION
Calcium di(2,5-dihydroxybenzenesulfonate) monohydrate.
Content: 99.0 per cent to 101.0 per cent (anhydrous substance).

CHARACTERS
Appearance: White or almost white, hygroscopic powder.
Solubility: Very soluble in water, freely soluble in anhydrous ethanol, very slightly soluble in 2-propanol, practically insoluble in methylene chloride.

IDENTIFICATION
A. Ultraviolet and visible absorption spectrophotometry.
B. Mix 1 mL of ferric chloride solution, 1 mL of a freshly prepared 10 g/L solution of potassium ferricyanide and 0.1 mL of nitric acid R. To this mixture add 5 mL of freshly prepared solution S (see Tests): a blue colour and a precipitate are immediately produced.
C. 2 mL of freshly prepared solution S gives reaction of calcium.

TESTS
Solution S: Dissolve 10.0 g in carbon dioxide-free water and dilute to 100 mL with the same solvent.
Appearance of solution: Solution S, when freshly prepared, is clear and colourless.
pH: 4.5 to 6.0 for solution S.
Related substances: To pass the test of Liquid chromatography
Iron: Maximum 10 ppm, determined on 10 mL of solution S.
Water: 4.0 per cent to 6.0 per cent, determined on 0.500 g.

ASSAY
Dissolve 0.200 g in a mixture of 10 mL of water R and 40 mL of dilute sulfuric acid R. Titrate with0.1 M cerium sulfate, determining the end-point potentiometrically. 1 mL of 0.1 M cerium sulfate is equivalent to 10.45 mg of C12H10CaO10S2.

STORAGE
In an airtight container, protected from light.

IMPURITIES
Specified impurities A: benzene-1,4-diol (hydroquinone).

For Original Monographs of IP Indian Pharmacopoeia BP British Pharmacopoeia USP US Pharmacopoeia FCC Food Grade product, please check with the respective web-pages or books.

Manufacturers:

MUBY CHEMICALS
Ambernath Mumbai, Ankleshwar Gujarat, India
TEL: (OFFICE) +912223770100, +912223726950
Current Date Time in India GMT+5:30

e-mail: info@mubychem.com

USA, Canada, Mexico and other American
neighbouring buyers may
e-mail: us@mubychem.com
Call toll-free 1-877-682-9243 (1-877-MUBYCHEM)

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Last 2 October, 2023

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Calcium Dobesilate Monohydrate SDS, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet
05-Oct-20

1. Product Identification

Product Name & Other Names: Calcium Dobesilate Monohydrate or 2,5-Dihydroxybenzenesulfonic acid calcium salt hydrate.
CAS Number: 20123-80-2
Molecular Weight: 436.4
Chemical Formula: C12H10CaO10S2-H2O
Relevant Uses: Industrial use only.
Relevant uses and uses advised against (if any): Industrial Manufacturing.
Suppliers: As per letterhead.

2. Hazards Identification

GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008

Skin corrosion/irritation Category 2
Serious eye irritation/damage Category 2A
Specific target organ toxicity, single exposure; Respiratory tract irritation Category 3

Labeling according GHS USA & Regulation (EC) No 1272/2008

GHS Label Elements
Irritant
Irritant

Signal Word: Warning

Hazard statements:
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.

Precautionary statements:
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P264: Wash thoroughly after handling.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P362: Take off contaminated clothing and wash before reuse.
P302+P352 - IF ON SKIN: Wash with plenty of soap and water.
P303+P361+P353 - IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
P304 + P340 - IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P332+P313: If skin irritation occurs: Get medical advice/attention.
P337+313: If eye irritation persists get medical advice/attention.

Classification according to EU Directives 67/548/EEC or 1999/45/EC:
Hazard Symbol:
Xi = Irritant
Risk Phrases:
R36/37/38 Irritating to eyes, respiratory system, and skin.

3. Composition/Information on Ingredients

Product Name & Other Names: Calcium Dobesilate Monohydrate or 2,5-Dihydroxybenzenesulfonic acid calcium salt hydrate.
CAS Number: 20123-80-2

4. First Aid Measures

Always seek medical attention after first aid measures are provided.

Inhalation: Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.
Ingestion: Never give anything by mouth to an unconscious person. Get medical attention.
Skin Contact: Wipe off excess material from skin then immediately flush skin with plenty of water for at least 15 minutes. Remove contaminated clothing and shoes. Get medical attention. Wash clothing before reuse. Thoroughly clean shoes before reuse.
Eye Contact: Immediately flush eyes with plenty of water for at least 15 minutes, lifting lower and upper eyelids occasionally. Get medical attention immediately.

5. Fire Fighting Measures

Flammability of the Product: May be combustible at high temperature.
Products of Combustion: Fumes, Calcium Oxide, Carbon dioxide & Carbon Monoxide and Sulfur Oxides.
Fire: Slightly flammable on heating.
Explosion: Slightly explosive on heating.
Fire Extinguishing Media: Use means suitable for extinguishing surrounding fire. Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures or when moistened under fire conditions, it may produce toxic or irritating fumes. Containers may explode on heating.

6. Accidental Release Measures

Personal precautions, protective equipment, and emergency procedures: Ventilate area of leak or spill. Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment Cleanup procedures and Storage:
Small Spill: Avoid dust formation. Avoid breathing dust. Ensure adequate ventilation. Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to local and regional authority requirements.
Large Spill: Avoid touching the spilled material. Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g. sand, earth, diatomaceous earth, vermiculite). Vacuum or sweep-up and remove to an approved disposal container. Finish cleaning by spreading water on the contaminated surface and allow evacuating as per law.

7. Handling and Storage

Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. In case of insufficient ventilation, wear suitable respiratory equipment. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like strong oxidizing agents.

8. Exposure Controls/Personal Protection

Airborne Exposure Limits: Not Specified.
Ventilation System
: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Dust deposits on floors and other surfaces may pick up moisture and cause the surfaces to become slippery and present safety hazards. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.

9. Physical and Chemical Properties

Appearance: Colorless white powder or crystals.
Odor: Faint to None.
Odor threshold: Not available.
pH: Not available.
Relative density: Not available.
Melting point/freezing point: Not available.
Initial boiling point and boiling range: Not available.
Flash point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility: It is soluble in water.
Viscosity: Not available.
Molecular Weight: 436.4
Chemical Formula: C12H10CaO10S2-H2O

10. Stability and Reactivity

Stability: Stable under ordinary conditions of use and storage.
Hazardous Decomposition Products: It emits Fumes, Calcium Oxide, Carbon dioxide & Carbon Monoxide and Sulfur Oxides.
Hazardous Polymerization: Will not occur.
Incompatibilities: Strong oxidizing agents.
Conditions to Avoid: Incompatibles and heat.

11. Toxicological Information

Acute toxicity: Harmful if inhaled. Irritating to skin and eyes.
Toxicity data:
LD50: Oral: Rat: 7061 mg/Kg
LD50: Intravenous: Rat: 750 mg/Kg
LD50: Intraperitoneal: Mouse: 876 mg/Kg
Carcinogenic Effects: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.
Mutagenic Effects: NA
Teratogenic Effects: NA
Developmental Toxicity: NA.

12. Ecological Information

Environmental Toxicity: Not available.
BOD5 and COD: Not available.
Products of Biodegradation: Possibly hazardous short-term degradation products are not likely. However, long term degradation products may arise.
Mutagenic Effects: Not available.
Teratogenic Effects: Not available.
Developmental Toxicity: Not available.
Reproductive Effects: No information available.

13. Disposal Considerations

Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. Processing use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose of container and unused contents in accordance with federal, state, and local requirements.

14. Transport Information

USA DOT & ADR/RID Europe: Not regulated.
Canada TDG Classification: Not regulated.
IATA: Not regulated.

15. Regulatory Information

USA:
California Prop. 65 Components
: This product does not contain any chemicals known to State of California to cause cancer, birth defects, or any other reproductive harm.
SARA 311/312: Immediate health hazard. See section 2.

Section 16 - Additional Information

European Labeling in Accordance with EC Directives:
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.

Classification according to EU Directives 67/548/EEC or 1999/45/EC:
Hazard Symbol:
Xi
Risk Phrases:
R36/37/38 Irritating to eyes, respiratory system, and skin.

Disclaimer:
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Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
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