Teriflunomide EP Grade Manufacturers, with SDS GHS MSDS Sheet |
Supplier, Manufacturer, Exporter of Teriflunomide EP Grade, Muby Chemicals of Mubychem Group, established in 1976, is the original manufacturers of Specialty Chemicals, Pharmaceutical Excipient, Fragrance Food & Flavor chemicals, Reagent Grade Chemicals, Shale Gas Fracturing Chemicals in India. Mubychem Group has several manufacturing facilities spread across Western India and world wide contacts and toll manufacturers. We are exporting globally to countries like USA, Canada, Europe, UAE, South Africa, Tanzania, Kenya, Egypt, Nigeria, Cameroon, Uganda, Turkey, Mexico, Brazil, Chile, Argentina, Dubai, Korea, Vietnam, Thailand, Malaysia, Indonesia, Australia, China, Germany, France, Italy Portugal, Bangladesh, etc. The products are offered as per required specifications and in correct shape and size in mm or meshs or microns as specified by the buyer. The participating units have one or more accreditations like FDA - cGMP and GLP approval, ISO-9001 Certified, "REACH" Registered, ISO-14001, ISO/IEC 17025, ISO-22000, FSSC 22000, ISO 45001, Kosher Certified, Halal Certified, HACCP, FSSAI. We offer Commercial Pure & IP BP EP Ph Eur USP NF JP FCC Food Grade Analytical Reagent Grades of Chemicals |
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Teriflunomide CAS Number 163451-81-8 or 108605-62-5, EINECS EC Number: 642-273-4 or 685-149-5, Molecular Formula: C12H9F3N2O2, Molecular Weight: 270.21, HS Code 29269000 or 29420000 or 38229010
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SDS MSDS Sheet of Teriflunomide Manufacturers
Teriflunomide
EP Grade Suppliers
Teriflunomide is sed to treat patients with the relapsing-remitting form of multiple sclerosis.
General Properties and Specifications of Teriflunomide:
Synonyms: (Z)-2-cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]but-2-enamide.
Appearance: White to almost white powder or crystals.
Assay: >98%
Melting Point: 227C to 231C literature.
Solubility: Soluble in DMSO.
Storage: Refrigerator. Preferably freezer.-20C. Heat Sensitive. Short term shipping may be ambient.
We supply Teriflunomide EP Grade as per monograph.
For Original Monographs of IP Indian Pharmacopoeia EP Ph Eur European Pharmacopoeia BP British Pharmacopoeia USP US Pharmacopoeia FCC Food Grade product, please check with the respective web-pages or books.
We also manufacture and supply as under:
Manufacturers:
MUBY CHEMICALS
Ambernath Mumbai, Ankleshwar Gujarat, India
TEL: (OFFICE) +912223770100, +912223726950
Current Date Time in India GMT+5:30
e-mail: info@mubychem.com
USA, Canada, Mexico and other American
neighbouring buyers may
e-mail: us@mubychem.com
Call toll-free 1-877-682-9243 (1-877-MUBYCHEM)
Copyright and Usual Disclaimer is Applicable.
Last
23 September, 2024
Exporters to USA Canada UAE Europe South Africa Tanzania Kenya Uganda Egypt Nigeria Turkey Mexico Brazil Argentina Chile Dubai etc.
Global or International Suppliers, Exporters, Importers, Manufacturers
I shall pass through this world, but once. If therefore, there is any good that I can do, or if there is any favor that I can show to a fellow human being, let me do it now. Let me not defer or neglect it. For I shall not tread this way again
Teriflunomide SDS, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet 23-Sept-24
1. Product Identification
Product Name & Other Names: Teriflunomide.
CAS No.: 163451-81-8 or 108605-62-5
EINECS EC Number: 642-273-4 or 685-149-5
Molecular Weight: 270.21
Chemical Formula: C12H9F3N2O2
Relevant uses and uses advised against (if any): Industrial Manufacturing
Supplier: As per letterhead.
2. Hazards Identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008
Acute toxicity, oral Category 4 (H302)
Labeling according to GHS & Regulation (EC) No 1272/2008
GHS Label Elements  Irritant |
Signal Words: Warning.
Hazard statements:
H302 Harmful if swallowed.
Precautionary statements:
P264: Wash --- thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P273 Avoid release to the environment.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P330: Rinse mouth.
P301+P310: IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P302+P352: IF ON SKIN: Wash with soap and water.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove
contact lenses, if present and easy to do. Continue rinsing.
P362: Take off contaminated clothing and wash before reuse.
P391: Collect spillage.
P405: Store in a closed container.
P501: Dispose of contents/ container to an approved waste disposal plant.
Classification according to EU Directives 67/548/EEC or 1999/45/EC:
Hazard Symbol:
Xn = Harmful
Risk Phrase:
R22 = Harmful if swallowed.
3. Composition/Information on Ingredients
Product Name & Other Names: Teriflunomide.
CAS No.: 163451-81-8 or 108605-62-5
EINECS EC Number: 642-273-4 or 685-149-5
4. First Aid Measures
Always seek medical attention after first aid measures are provided.
Inhalation: Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.
Ingestion: Contact a poison control center or physician for treatment advice. Never give anything by mouth to an unconscious person. Get medical attention.
Skin Contact: Wipe off excess material from skin then immediately flush skin with plenty of water for at least 15 minutes. Remove contaminated clothing and shoes. Get medical attention. Wash clothing before reuse. Thoroughly clean shoes before reuse.
Eye Contact: Immediately flush eyes with plenty of water for at least 15 minutes, lifting lower and upper eyelids occasionally. Get medical attention immediately.
5. Fire Fighting Measures
Flammability of the Product: Non-flammable. However, it can burn at high temperature.
Products of Combustion: During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Hydrogen fluoride, Nitrogen oxides carbon oxides and fumes can be formed.
Fire Extinguishing Media: Use water spray or fog for cooling exposed containers. Fine water spray, normal foam, dry agent (carbon dioxide, dry chemical powder) can be used. Exercise caution when fighting any chemical fire. Avoid solid water jets as they can scatter the fire.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes. Fire-extinguishing work is done from the windward and a suitable fire-extinguishing method according to the surrounding situation is used. Uninvolved persons should evacuate to a safe place.
6. Accidental Release Measures
Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment cleanup procedures and Storage:
Small Spill: Avoid dust formation. Avoid breathing dust. Ensure adequate ventilation. Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to local and regional authority requirements.
Large Spill: Contain spilled material. Avoid touching the spilled material. Do not let the product enter drains. Use a shovel to put the material into a convenient waste disposal container. Do not contaminate the environment.
7. Handling and Storage
Precautions for safe handling: Toxic if swallowed. Do not ingest. Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. Provide appropriate exhaust ventilation at places where dust is formed. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Do not leave the material container open. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatibles like oxidizing agents. Storage: Refrigerator. Preferably freezer.-20C. Heat Sensitive. Short term shipping may be ambient.
8. Exposure Controls/Personal Protection
Airborne Exposure Limits: No data found.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full-face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.
9. Physical and Chemical Properties
Appearance: White to almost white powder or crystals.
Odor: Not available.
Odor threshold: Not available.
pH: Not available.
Relative density: Not available.
Boiling Point: Not available.
Melting Point: 227C to 231C literature.
Flash point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility: Soluble in DMSO.
Viscosity: Not available.
Molecular Weight: 270.21
Chemical Formula: C12H9F3N2O2
10. Stability and Reactivity
Stability: Stable under recommended conditions of use and storage.
Hazardous Decomposition Products: Hydrogen fluoride, Nitrogen oxides carbon oxides and fumes can be formed.
Hazardous Polymerization: Will not occur.
Incompatibilities: Strong oxidizing agents.
Conditions to Avoid: Incompatibles. Avoid Heat & incompatibles.
11. Toxicological Information
Toxicity data
LD50 Oral - Rat – 500.1 mg/kg
Carcinogenic Effects: Not known to be a carcinogen by IARC NTP ACGIH OSHA.
Mutagenic Effects: Not available.
Teratogenic Effects: Not available.
Developmental Toxicity: Not available.
12. Ecological Information
Toxicity to fish: No information available.
Persistence and Degradability: No information available.
Mobility: No information available.
Bioaccumulation/ Accumulation: No information available.
Results of PBT and vPvB assessment: No data available for assessment.
13. Disposal Considerations
This product is a registered pesticide. Pesticide wastes are acutely hazardous. Improper disposal is a violation of Law. Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. Dispose of containers and unused contents in accordance with federal, state, and local requirements.
14. Transport Information
DOT USA, TDG Canada & ADR/RID Europe : Not dangerous goods.
IATA: Not dangerous goods.
IMDG/IMO: Not dangerous goods.
15. Regulatory Information
USA:
SARA 311/312: Acute Health Hazard. See section 2.
SARA 313 Components: Not applicable.
16. Other Information
European Labeling in Accordance with EC Directives:
H302 Harmful if swallowed.
Classification according to EU Directives 67/548/EEC or 1999/45/EC:
Hazard Symbol:
Xn = Harmful
Risk Phrase:
R22 = Harmful if swallowed.
Disclaimer:
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Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
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