Nonoxynol 9 or Nonoxinol 9 USP BP Ph Eur Grade Manufacturers, with SDS GHS MSDS Sheet |
Supplier, Manufacturer, Exporter of Nonoxynol 9 or Nonoxinol 9 USP BP Ph Eur Grade, Muby Chemicals of Mubychem Group, established in 1976, is the original manufacturers of Specialty Chemicals, Pharmaceutical Excipient, Fragrance Food & Flavor chemicals, Reagent Grade Chemicals, Shale Gas Fracturing Chemicals in India. Mubychem Group has several manufacturing facilities spread across Western India and world wide contacts and toll manufacturers. We are exporting globally to countries like USA, Canada, Europe, UAE, South Africa, Tanzania, Kenya, Egypt, Nigeria, Cameroon, Uganda, Turkey, Mexico, Brazil, Chile, Argentina, Dubai, Korea, Vietnam, Thailand, Malaysia, Indonesia, Australia, China, Germany, France, Italy Portugal, Bangladesh, etc. The products are offered as per required specifications and in correct shape and size in mm or meshs or microns as specified by the buyer. The participating units have one or more accreditations like FDA - cGMP and GLP approval, ISO-9001 Certified, "REACH" Registered, ISO-14001, ISO/IEC 17025, ISO-22000, FSSC 22000, ISO 45001, Kosher Certified, Halal Certified, HACCP, FSSAI. We offer Commercial Pure & IP BP EP Ph Eur USP NF JP FCC Food Grade Analytical Reagent Grades of Chemicals |
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Nonoxynol 9 or Nonoxinol 9 CAS Number 26027-38-3 or 26571-11-9, EINECS EC Number: 247-816-5, Molecular Formula: C33H60O10, Molecular Weight: 616.83, HS Code 29094990
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SDS MSDS Sheet of Nonoxynol 9 or Nonoxinol 9 Manufacturers
Nonoxynol 9
Nonoxinol 9 USP BP Ph Eur Grade Pure Suppliers
Nonoxynol-9 or N-9 or Nonoxinol 9 is a common spermicide used in vaginal contraceptive products like foams, gels, films, and sponges to prevent pregnancy by damaging sperm membrane. While available over the counter for over 60 years, it does not protect against STIs or HIV and can cause vaginal irritation, increasing infection risks if used frequently.
General Properties and specifications of Nonoxynol 9:
Appearance: Clear, colourless or light yellow, viscous liquid.
Assay: It contains NLT 90.0% and NMT 110.0% of nonoxynol 9.
Melting Point: about 6C literature.
Solubility: Soluble in water, ethanol, ehtylene glycol, ethylene dichloride, xylene, corn oil.
Storage: Preserve in tight containers.
Nonoxynol 9 USP Grade Specifications:
α-(p-Nonylphenyl)-ω-hydroxynona(oxyethylene)
CAS 26027-38-3
DEFINITION
Nonoxynol 9 is an anhydrous liquid mixture consisting chiefly of monononylphenyl ethers of polyethylene glycols corresponding to the formula:
C9H19C6H4(OCH2CH2)nOH
in which the average value of n is 9. It contains NLT 90.0% and NMT 110.0% of Nonoxynol 9.
IDENTIFICATION
A. Infrared Absorption.
B. The retention time of the Sample solution corresponds to that of the Standard solution.
Assay: 90% to 100%
Free Ethylene Oxide: To pass the test by chromatography.
Limit of Dioxane: To pass the test.
Polyethylene Glycol: To pass the test.
Cloud Point: To pass the test. Acceptance criteria: 52C to 56C.
Fats and Fixed Oils, Acid Value: NMT 0.2
Water Determination: NMT 0.5%
Packaging and Storage: Preserve in tight containers.
Nonoxinol 9 BP Ph Eur Grade:
Action and use: Spermatocide.
DEFINITION
α-(4-Nonylphenyl)-ω-hydroxynona(oxyethylene).
Mixture consisting mainly of monononylphenyl ethers of macrogols corresponding to the formula: C9H19C6H4-[OCH2-CH2]n-OH where the average value of is 9. It may contain free macrogols.
CHARACTERS
Appearance: Clear, colourless or light yellow, viscous liquid.
Solubility: Miscible with water, with ethanol (96 per cent) and with vegetable oils.
IDENTIFICATION
A. Infrared absorption spectrophotometry.
>B. Cloud point.
TESTS
Acidity or alkalinity: Boil 1.0 g with 20 mL of carbon dioxide-free water for 1 min, with constant stirring. Cool and filter. To 10 mL of the filtrate, add 0.05 mL of bromothymol blue solution. Not more than 0.5 mL of 0.01 M hydrochloric acid or 0.01 M sodium hydroxide is required to change the colour of the indicator.
Hydroxyl value: 84 to 94.
Cloud point: 52C to 58C.
Ethylene oxide and dioxan: Maximum 1 ppm of ethylene oxide and maximum 10 ppm of dioxan.
Water: Maximum 0.5 per cent, determined on 2.00 g.
Total ash: Maximum 0.4 per cent, determined on 1.0 g.
Storage: In an airtight container.
For Original Monographs of IP Indian Pharmacopoeia EP Ph Eur European Pharmacopoeia BP British Pharmacopoeia USP US Pharmacopoeia FCC Food Grade product, please check with the respective web-pages or books.
We also manufacture and supply as under:
Manufacturers:
MUBY CHEMICALS
Ambernath Mumbai, Ankleshwar Gujarat, India
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Last 13 May, 2026
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Nonoxynol 9 or Nonoxinol 9 SDS GHS, Safety Data Sheet
MSDS GHS, Material Safety Data Sheet 13-May-26
1. Product Identification
Product Name & Other Names: Nonoxynol 9 or Nonoxinol 9.
CAS No.: 26027-38-3 or 26571-11-9
EINECS EC No.: 247-816-5
Molecular Formula: C33H60O10
Molecular Weight: 616.83
Relevant uses and uses advised against (if any): Industrial Manufacturing.
Suppliers: As per letterhead.
2. Hazards Identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Hazard Class and Category Code(s), Regulation (EC) No 1272/2008 (CLP):
Acute toxicity, Oral (Category 4) H302
Skin irritation (Category 2), H315
Serious eye damage (Category 1), H318
Long-term (chronic) aquatic hazard (Category 3), H412
Labeling according to Regulation (EC) No 1272/2008
GHS Label Elements Corrosive |
Signal Words: Danger
Hazard statements:
H302: Harmful if swallowed.
H318 Causes serious eye damage.
H373 May cause damage to organs through prolonged or repeated exposure.
H412 Harmful to aquatic life with long lasting effects.
Precautionary statements:
P210: Keep away from heat/sparks/open flames/hot surfaces – No smoking.
P233: Keep container tightly closed.
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P264: Wash … thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P273: Avoid release to the environment.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P391: Collect spillage.
P301+P312+P330: IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth.
P302+352: IF ON SKIN: Wash with soap and water.
P303+361+353: IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
P305+351+338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do – continue rinsing.
P403+233+235: Store in a well-ventilated place. Keep container tightly closed. Keep cool.
P501: Dispose of contents/container to authorized agents only.
Classification according to EU Directives 67/548/EEC or 1999/45/EC:
Hazard symbols:
Xi Irritant.
C Corrosive.
Xn Harmful.
N Dangerous for the environment,
R-phrases:
R22 Harmful if swallowed
R35 Causes severe burns
R41 Risk of serious damage to eyes.
R52/53 Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
3. Composition/Information on Ingredients
Product Name & Other Names: Nonoxynol 9 or Nonoxinol 9.
CAS No.: 26027-38-3 or 26571-11-9
EINECS EC No.: 247-816-5
4. First Aid Measures
Always seek medical attention after first aid measures are provided.
Inhalation: Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.
Ingestion: Never give anything by mouth to an unconscious person. Get medical attention.
Skin Contact: Wipe off excess material from skin then immediately flush skin with plenty of water for at least 15 minutes. Remove contaminated clothing and shoes. Get medical attention. Wash clothing before reusing. Thoroughly clean shoes before reusing them. Get medical attention.
Eye Contact: Immediately flush eyes with plenty of water for at least 15 minutes, lifting lower and upper eyelids occasionally. Get medical attention immediately.
5. Fire Fighting Measures
Fire: May be flammable at high temperature.
Products of Combustion: Carbon oxides and fumes.
Fire Extinguishing Media: Use water spray or fog, alcohol-resistant foam, dry chemical, or carbon dioxide. Cool containing vessels with water jets to prevent pressure build-up, auto-ignition, or explosion. Do not allow run-off from firefighting to enter drains or water courses.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes. Fire-extinguishing work is done from the windward and a suitable fire-extinguishing method according to the surrounding situation is used. Uninvolved people should evacuate to a safe place.
6. Accidental Release Measures
Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Prevent further leakage or spillage if safe to do so. Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment cleanup procedures and Storage: Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g., sand, earth, diatomaceous earth, vermiculite). Vacuum or sweep-up and remove it to an approved disposal container.
Small Spill: Avoid mist formation. Avoid breathing mist. Ensure adequate ventilation. Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to local and regional authority requirements.
Large Spill: Remove all sources of ignition. Provide proper ventilation. Absorb the material on a porous, inert material such as earth, sand, or vermiculite. If solid/powder - carefully sweep up the material without causing dust. Dispose of it in accordance with local regulations.
7. Handling and Storage
Precautions for safe handling: Keep away from sources of ignition - No smoking. Take measures to prevent the build-up of electrostatic charge. Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. In case of insufficient ventilation, wear suitable respiratory equipment. Wash thoroughly after handling it. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original containers. Keep air contact to a minimum. Do not leave the material container open. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like Oxidizing agents and bases. Keep the product in its original container well sealed, in a dry and ventilated area, away from potential sources of ignition and protected from light. Protect against physical damage. Storage: Preserve in tight containers.
8. Exposure Controls/Personal Protection
Airborne Exposure Limits: Not established.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full-face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.
9. Physical and Chemical Properties
Appearance: Clear, colourless or light yellow, viscous liquid.
Odor: Odorless.
Odor threshold: Not applicable.
pH: Not available.
Relative Density: Not available.
Boiling Point: Not available.
Melting Point: about 6C. Literature.
Flash Point: Not available.
Auto-ignition Temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor Pressure (mm Hg): Not available.
Vapor Density (Air=1): Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility: Soluble in water, ethanol, ethylene glycol, ethylene dichloride, xylene, corn oil.
Viscosity: Not available.
Molecular Formula: C33H60O10
Molecular Weight: 616.83
10. Stability and Reactivity
Stability: Stable under recommended conditions of use and storage. Vapor/air-mixtures are explosive at intense warming.
Hazardous Decomposition Products: It emits Carbon oxides and fumes.
Hazardous Polymerization: Will not occur.
Incompatibilities: Oxidizing agents and bases.
Conditions to Avoid: Incompatibles, heat, flames, and sparks & light.
11. Toxicological Information
Toxicity data
LD50 Oral - Rat - 1410 mg/kg.
LD50 Dermal - Rabbit - 2380 mg/kg.
Carcinogenicity: No information found.
Reproductive Effects: No information found.
Mutagenicity: No information found.
Neurotoxicity: No information found.
12. Ecological Information
Environmental Toxicity: Harmful to aquatic life with long lasting effects.
Toxicity to fish: LC50 (Poecilia sp.): 16.4 mg/l, Exposure time: 48.0 h, flow-through test.
Toxicity to daphnia and other aquatic invertebrates: LC50 (Daphnia magna (Water flea)): 18.2 mg/l, Exposure time: 48 h, flow-through test.
Persistence and Degradability: Persistence is unlikely due to its water solubility.
Mobility: Will be mobile in the environment due to its water solubility.
Bioaccumulation/ Accumulation: No information available.
Results of PBT and vPvB assessment: No data available.
13. Disposal Considerations
Whatever cannot be saved for recovery, or recycling should be managed in an appropriate and approved waste disposal facility. Processing use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose of containers and unused contents in accordance with federal, state, and local requirements.
14. Transport Information
DOT USA, TDG Canada & ADR/RID Europe: Not regulated.
IMDG/IMO: Not regulated.
IATA/ICAO: Not regulated.
15. Regulatory Information
USA:
SARA 311/312 Hazards: Immediate Health Hazard: Acute Yes, Chronic Health Hazard.
16. Other Information
European Labeling in Accordance with EC Directives:
H302: Harmful if swallowed.
H318 Causes serious eye damage.
H412 Harmful to aquatic life with long lasting effects.
Classification according to EU Directives 67/548/EEC or 1999/45/EC:
Hazard symbols:
Xi Irritant.
C Corrosive.
Xn Harmful.
N Dangerous for the environment,
R-phrases:
R22 Harmful if swallowed
R35 Causes severe burns
R41 Risk of serious damage to eyes.
R52/53 Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Disclaimer:
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Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
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