L-Lysine monohydrochloride or Lysine Hydrochloride or 2,6-Diaminohexanoic acid monohydrochloride or 2,6-Diaminohexanoic Acid Hydrochloride BP Ph Eur USP FCC Food Grade Manufacturers, with SDS GHS MSDS Sheet |
Supplier, Manufacturer, Exporter of L-Lysine monohydrochloride or Lysine Hydrochloride, Muby Chemicals of Mubychem Group, established in 1976, is the original manufacturers of Specialty Chemicals, Pharmaceutical Excipient, Fragrance Food & Flavor chemicals, Reagent Grade Chemicals, Shale Gas Fracturing Chemicals in India. Mubychem Group has several manufacturing facilities spread across Western India and world wide contacts and toll manufacturers. We are exporting globally to countries like USA, Canada, Europe, UAE, South Africa, Tanzania, Kenya, Egypt, Nigeria, Cameroon, Uganda, Turkey, Mexico, Brazil, Chile, Argentina, Dubai, Korea, Vietnam, Thailand, Malaysia, Indonesia, Australia, China, Germany, France, Italy, Portugal, Bangladesh, etc. The products are offered as per required specifications and in correct shape and size in mm or meshs or microns as specified by the buyer. The participating units have one or more accreditations like FDA - cGMP and GLP approval, ISO-9001 Certified, "REACH" Registered, ISO-14001, ISO/IEC 17025, ISO-22000, FSSC 22000, ISO 45001, Kosher Certified, Halal Certified, HACCP, FSSAI. We offer Commercial Pure & IP BP EP Ph Eur USP NF JP FCC Food Grade Analytical Reagent Grades of Chemicals |
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L-Lysine monohydrochloride or Lysine Hydrochloride or 2,6-Diaminohexanoic acid monohydrochloride or 2,6-Diaminohexanoic Acid Hydrochloride: CAS Number: 657-27-2, EINECS EC Number: 211-519-9, Molecular Formula: C6H14N2O2-HCl or H2N(CH2)4CH(NH2)CO2H-HCl, Molecular Weight: 182.65, HS Code ---**
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SDS MSDS Sheet of L-Lysine monohydrochloride or Lysine Hydrochloride Manufacturers
L-Lysine monohydrochloride
Lysine Hydrochloride or 2,6-Diaminohexanoic acid monohydrochloride or 2,6-Diaminohexanoic Acid Hydrochloride Pure Suppliers
Lysine Hydrochloride USP Grade
C6H14N2O2-HCl --- 182.65
Lysine Hydrochloride contains not less than 98.5 percent and not more than 101.5 percent of C6H14N2O2.HCl, as L-lysine hydrochloride, calculated on the dried basis.
Packaging and storage: Preserve in well-closed containers.
Identification: Infrared Absorption.
Specific rotation: between +20.4 and +21.4 .
Loss on drying: Dry it at 105C for 3 hours: it loses not more than 0.4% of its weight.
Residue on ignition: not more than 0.1%.
Sulfate: A solution containing 0.33 g shows no more sulfate than corresponds to 0.10 mL of 0.020 N sulfuric acid (0.03%).
Iron: 0.003%.
Heavy metals: 0.0015%.
Chromatographic purity: To pass the test.
Content of chloride: Transfer about 350 mg, accurately weighed, to a porcelain casserole, and add 140 mL of water and 1 mL of dichlorofluorescein. Mix, and titrate with 0.1 N silver nitrate until the silver chloride flocculates and the mixture acquires a faint pink color. Each mL of 0.1 N silver nitrate is equivalent to 3.545 mg of chloride: between 19.0% and 19.6% is found.
Assay: Transfer about 90 mg of Lysine Hydrochloride, accurately weighed, to a 125-mL flask, and dissolve in a mixture of 3 mL of formic acid and 50 mL of glacial acetic acid. Add 10 mL of mercuric acetate and titrate with 0.1 N perchloric acid, determining the endpoint potentiometrically. Perform a blank determination, and make any necessary correction. Each mL of 0.1 N perchloric acid is equivalent to 9.133 mg of C6H14N2O2.HCl.
Lysine Hydrochloride BP Ph Eur Grade
C6H14N2O2-HCl --- 182.7 --- CAS 657-27-2
Action and use: Amino acid.
DEFINITION
Lysine hydrochloride contains not less than 98.5 per cent and not more than the equivalent of 101.0 per cent of (S)-2,6-diaminohexanoic acid hydrochloride, calculated with reference to the dried substance.
CHARACTERS
A white or almost white, crystalline powder or colourless crystals, freely soluble in water, slightly soluble in alcohol.
IDENTIFICATION
First identification: A, B, E.
Second identification: A, C, D, E.
A. It complies with the test for specific optical rotation.
B. Examine by infrared absorption spectrophotometry, comparing with the spectrum obtained with lysine hydrochloride CRS. Examine the substances prepared as discs. If the spectra obtained show differences, dissolve the substance to be examined and the reference substance separately in the minimum volume of water, evaporate to dryness at 60C, and record new spectra using the residues.
C. Examine the chromatograms obtained in the test for ninhydrin-positive substances. The principal spot in the chromatogram obtained with test solution (b) is similar in position, colour and size to the principal spot in the chromatogram obtained with reference solution (a).
D. To 0.1 ml of solution S (see Tests) add 2 ml of water and 1 ml of a 50 g/l solution of phosphomolybdic acid. A yellowish-white precipitate is formed.
E. To 0.1 ml of solution S add 2 ml of water. The solution gives reaction (a) of chlorides.
TESTS
Solution S: Dissolve 5.0 g in carbon dioxide-free water R prepared from distilled water and dilute to 50 ml with the same solvent.
Appearance of solution: Solution S is clear and not more intensely coloured than reference solution.
Specific optical rotation: Dissolve 2.00 g in hydrochloric acid and dilute to 25.0 ml with the same acid. The specific optical rotation is + 21.0 to + 22.5, calculated with reference to the dried substance.
Ninhydrin-positive substances: To pass the test.
Sulphates: Dilute 5 ml of solution S to 15 ml with distilled water R. The solution complies with the limit test for sulphates (300 ppm).
Ammonium: 50 mg complies with limit test B for ammonium (200 ppm). Prepare the standard using 0.1 ml of ammonium standard solution (100 ppm NH4).
Iron: In a separating funnel, dissolve 0.33 g in 10 ml of dilute hydrochloric acid. Shake with three quantities, each of 10 ml, of methyl isobutyl ketone, shaking for 3 min each time. To the combined organic layers add 10 ml of water and shake for 3 min. The aqueous layer complies with the limit test for iron (30 ppm).
Heavy metals: 12 ml of solution S complies with limit test A for heavy metals (10 ppm).
Loss on drying: Not more than 0.5 per cent, determined on 1.000 g by drying in an oven at 105C.
Sulphated ash: Not more than 0.1 per cent, determined on 1.0 g.
ASSAY
Dissolve 0.150 g in 5 ml of anhydrous formic acid. Add 50 ml of anhydrous acetic acid. Titrate with 0.1 M perchloric acid, determining the end-point potentiometrically. 1 ml of 0.1 M perchloric acid is equivalent to 18.27 mg of C6H15ClN2O2.
STORAGE
Store protected from light.
L-Lysine Monohydrochloride FCC Food Grade
2,6-Diaminohexanoic Acid Hydrochloride
C6H14N2O2-HCl --- Formula wt 182.65 --- CAS: [657-27-2]
DESCRIPTION
L-Lysine Monohydrochloride occurs as a white or nearly white, free-flowing, crystalline powder. It is freely soluble in water, but it is almost insoluble in alcohol and in ether. It melts at about 260° with decomposition.
Function: Nutrient.
Identification: The infrared absorption spectrum of the sample exhibits relative maxima at the same wavelengths as those of a typical spectrum as shown in the section on Infrare-Spectra, using the same test conditions as specified therein.
Assay: Not less than 98.5% and not more than 101.5% of C6H14N2O2·HCl, calculated on the dried basis.
Lead: Not more than 5 mg/kg.
Loss on Drying: Not more than 1.0%.
Optical (Specific) Rotation: D20°: Between +20.3° and +21.5°, calculated on the dried basis; or D25°: Between +20.4° and +21.4°, calculated on the dried basis.
Residue on Ignition: Not more than 0.2%.
For Original Monographs of IP Indian Pharmacopoeia BP British Pharmacopoeia USP US Pharmacopoeia FCC Food Grade product, please check with the respective web-pages or books.
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Manufacturers:
MUBY CHEMICALS
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L-Lysine monohydrochloride SDS, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet 26-Oct-20
Section 1: Chemical Product Identification
Product Name & Other Names: L-Lysine monohydrochloride or Lysine Hydrochloride or 2,6-Diaminohexanoic acid monohydrochloride or 2,6-Diaminohexanoic Acid Hydrochloride.
CAS#: 657-27-2
EINECS EC Number: 211-519-9
Molecular Weight: 182.65
Chemical Formula: C6H14N2O2-HCl or H2N(CH2)4CH(NH2)CO2H-HCl
Relevant uses and uses advised against (if any): Industrial Manufacturing.
Suppliers: As per letterhead.
Section 2: Hazards Identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008
Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
This substance is not classified as dangerous according to Directive 67/548/EEC.
Labeling according to GHS & Regulation (EC) No 1272/2008
GHS Label Elements None |
Signal Words: None
Hazards not otherwise classified (HNOC):
May causes mild skin irritation.
May causes mild eye irritation.
Precautionary statements:
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P262: Do not get in eyes, on skin, or on clothing.
P281: Use personal protective equipment as required.
P302+P352: IF ON SKIN: Wash with plenty of soap and water.
P303+P361+P353: IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+313: If eye irritation persists get medical advice/attention.
Section 3: Composition and Information on Ingredients
Product Name/Synonyms: L-Lysine monohydrochloride or Lysine Hydrochloride or 2,6-Diaminohexanoic acid monohydrochloride or 2,6-Diaminohexanoic Acid Hydrochloride.
CAS#: 657-27-2
EINECS EC Number: 211-519-9
Section 4: First Aid Measures
Always get medical attention after the first aid is over.
Eye Contact: Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Get medical attention if irritation occurs.
Skin Contact: Wash with soap and water. Cover the irritated skin with an emollient. Get medical attention if irritation develops.
Inhalation: If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.
Ingestion: Do Not induce vomiting unless directed to do so by medical personnel. If large quantities of this material are swallowed, call a physician immediately. Loosen tight clothing.
Notes to Physician: Provide general supportive measures and treat symptomatically.
Section 5: Fire and Explosion Data
Flammability of the Product: Not classed as fire hazard but it may be combustible at high temperature.
Auto-Ignition Temperature: Not available.
Products of Combustion: Oxides of carbon, hydrogen chloride, nitrogen and ammonia along with fumes .
Fire Fighting Media and Instructions: Use DRY chemical powder, water spray, carbon dioxide, fog or foam. Do not use water jet. In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes. Fire-extinguishing work is done from the windward and the suitable fire-extinguishing method according to the surrounding situation is used. Uninvolved persons should evacuate to a safe place. In case of fire in the surroundings: Remove movable containers if safe to do so.
Section 6: Accidental Release Measures
Personal precautions, protective equipment and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Ensure adequate ventilation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil or water sources.
Methods and materials used for containment Cleanup procedures and Storage:
Small Spill: Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to legal requirements.
Large Spill: Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and allow to drain or as required by law. Use personal protective equipment. Keep people away from and upwind of spill/leak. Entry to non-involved personnel should be controlled around the leakage area by roping off, etc.
Section 7: Handling and Storage
Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. Wash thoroughly after handling. Do not drink, eat or smoke while handling. Avoid contact with skin, eyes and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cool, dry and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Do not leave the material container open. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like oxidizing agents. Empty containers pose a fire risk, evaporate the residue under a fume hood. Ground all equipment containing material.
Section 8: Exposure Controls/Personal Protection
Engineering Controls: Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits.
Exposure Limits: Not established.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Dust deposits on floors and other surfaces may pick up moisture and cause the surfaces to become slippery and present safety hazards. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.
Section 9: Physical and Chemical Properties
Physical state and appearance: White powder or crystals.
Odor: Not available.
Odor threshold: Not available.
pH: 5,0 - 6 at 91,3 g/l @ 25C
Relative density: 1.28
Boiling Point: Not available.
Melting Point: Melting point/range: 263 °C.
Flash point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility: Soluble in water.
Viscosity: Not available.
Molecular Weight: 182.65
Chemical Formula: C6H14N2O2-HCl or H2N(CH2)4CH(NH2)CO2H-HCl
Section 10: Stability and Reactivity Data
Stability: Stable under normal conditions.
Incompatibility with various substances: Oxidizing agents light and heat.
Hazardous Decomposition Products: May form nitrogen oxides, carbon dioxide and carbon monoxide and ammonia, hydrogen chloride and various hydrocarbon fume.
Polymerization: Will not occur.
Section 11: Toxicological Information
Toxicity to Animals:
LS50/intraperitoneal/rat = Not available.
LD50/oral/rat = 10000 mg/kg.
ipr-rat LD50:4019 mg/kg.
Acute inhalation toxicity: LC50 Rat: > 5.51 mg/l; 4 h ; dust/mist .
Germ cell mutagenicity: No data available.
Reproductive toxicity: No data available.
Carcinogenicity: The substance is not a known carcinogen as per any authorized agency.
Section 12: Ecological Information
Toxicity to fish: semi-static test LC50 Oryzias latipes (Orange-red killifish): > 103 mg/l; 96 h.
Toxicity to daphnia and other aquatic invertebrates: semi-static test EC50 Daphnia magna (Water flea): > 106 mg/l; 48 h
BOD5 and COD: Not available.
Products of Biodegradation: Possibly hazardous short-term degradation products are not likely. However, long term degradation products may arise.
Toxicity of the Products of Biodegradation: Not available.
Bio accumulative potential: Readily biodegradable.
Mobility in soil: No data available. Expected to be mobile due to water solubility.
Results of PBT and vPvB assessment: Not available.
Section 13: Disposal Considerations
Waste Disposal: To be disposed as per legal requirement.
Section 14: Transport Information
DOT USA, TDG Canada & ADR/RID Europe: Not a DOT controlled material (United States).
IMDG/IMO: Not regulated.
IATA: Not regulated.
Section 15: Other Regulatory Information
USA Federal and State Regulations:
SARA 302: Not subject to the reporting requirements of SARA Title III, Section 302.
SARA 313: Not listed.
SARA 311/312 Hazards: No SARA Hazards.
California Prop. 65 Components: This product does not contain any chemicals known to State of California to cause cancer, birth defects, or any other reproductive harm.
Section 16: Other Information
Disclaimer:
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Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
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