Ethyl acetate or Ethyl ethanoate Manufacturers, with SDS GHS MSDS Sheet

Supplier, Manufacturer, Exporter of Ethyl acetate or Ethyl ethanoate, Muby Chemicals of Mubychem Group, established in 1976, is the original manufacturers of Specialty Chemicals, Pharmaceutical Excipient, Fragrance Food & Flavor chemicals, Reagent Grade Chemicals, Shale Gas Fracturing Chemicals in India. Mubychem Group has several manufacturing facilities spread across Western India and world wide contacts and toll manufacturers. We are exporting globally to countries like USA, Canada, Europe, UAE, South Africa, Tanzania, Kenya, Egypt, Nigeria, Cameroon, Uganda, Turkey, Mexico, Brazil, Chile, Argentina, Dubai, Korea, Vietnam, Thailand, Malaysia, Indonesia, Australia, China, Germany, France, Italy, Portugal, Bangladesh, etc.

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Ethyl acetate or Ethyl ethanoate: CAS Number: 141-78-6, EINECS EC Number: 205-500-4, Molecular Formula: C4H8O2, Molecular Weight: 88.10, HS Code 29153100, FEMA Number 2414

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SDS MSDS Sheet of Ethyl acetate or Ethyl ethanoate Manufacturers

Ethyl acetate
Ethyl ethanoate Pure Suppliers
Ethyl acetate

Ethyl acetate or Ethyl ethanoate is the organic compound with the formula C4H8O2. This colorless liquid has a characteristic sweet fruity smell and is used in glues, nail polish removers, and in the decaffeination process of tea and coffee. Ethyl acetate is used primarily as a solvent and diluent. It is commonly used to clean circuit boards and in some nail varnish removers. It is also used in paints. Ethyl acetate is present in confectionery, perfumes, and fruits. It has E number of E1504.

General Properties and Specifications of Ethyl acetate or Ethyl ethanoate:
Appearance: Colorless liquid.
Assay: 99.5%
Odor: Sweet fruity odor.
Relative density: about 0.9
Melting point: -84C.
Boiling point: 77C.
Flash point: -4C.
Autoignition temperature: 427C.
Solubility: Soluble in water. Miscible with ethanol, acetone, and benzene.

Ethyl Acetate USP NF Grade Specifications:
C4H8O2 --- 88.11
Acetic acid, ethyl ester;
Ethyl acetate CAS 141-78-6
Ethyl Acetate contains NLT 99.0% and NMT 100.5% of ethyl acetate (C4H8O2).
A. Infrared Absorption
To pass the test by titrimetry.
Acceptance criteria: 99.0% to 100.5%
Limit of Nonvolatile Residue:
Sample: Ethyl Acetate
Analysis: Evaporate the Sample in a tared porcelain dish on a steam bath, and dry at 105C for 1 h.
Acceptance criteria: NMT 0.02%
Limit of Methyl Compounds: To pass the test.
Chromatographic Purity: To pass the test.
Acceptance criteria: The area of the ethyl acetate peak is NLT 99.5% of the sum of the areas of all the peaks.
Sample solution: 2.0 mL of Ethyl Acetate in 10 mL of neutralized alcohol
Analysis: Add 2 drops of phenolphthalein to the Sample solution. Neutralize with 0.10 N sodium hydroxide.
Acceptance criteria: NMT 0.10 mL of 0.10 N sodium hydroxide is required.
Readily Carbonizable Substances Test:
Sample: 2 mL of Ethyl Acetate
Analysis: Add the Sample carefully to 10 mL of sulfuric acid to form separate layers.
Acceptance criteria: No dark zone is developed within 15 min.
Specific Gravity: 0.894–0.898
Packaging and Storage: Preserve in tight containers and avoid exposure to excessive heat.

Ethyl Acetate BP Ph Eur Specifications:
C4H8O2 --- 88.1 --- CAS 141-78-6
Action and use: Excipient.
Ethyl ethanoate.
Appearance: Clear, colourless, volatile liquid.
Solubility: Soluble in water, miscible with acetone, with ethanol (96 per cent) and with methylene chloride.
First identification: B
Second identification: A, C, D
A. Boiling point: 76C to 78C.
B. Infrared absorption spectrophotometry.
C. It gives the reaction of acetyl.
D. It gives the reaction of esters.
Appearance of solution: The solution is clear and colourless.
Mix 1 mL of the substance to be examined and 15 mL of water.
Acidity: To 10 mL of ethanol (96 per cent) add 0.1 mL of phenolphthalein solution and 0.01 M sodium hydroxide until the colour changes to pink. Add 5.5 mL of the substance to be examined and 0.25 mL of 0.02 M sodium hydroxide. The solution remains pink for not less than 15 s.
Relative density: 0.898 to 0.902.
Refractive index: 1.370 to 1.373.
Reaction with sulfuric acid: Carefully add 2 mL to 10 mL of sulfuric acid. After 15 min, the interface between the 2 liquids is not coloured.
Related substances: to pass the test by Gas chromatography.
Limit: --total: not more than 0.2 per cent of the area of the principal peak.
Residue on evaporation: Maximum 30 ppm.
Evaporate 100.0 g to dryness on a water-bath and dry in an oven at 100-105C. The residue weighs not more than 3 mg.
Water: Maximum 0.1 per cent, determined on 10.0 mL.
Protected from light, at a temperature not exceeding 30C.
Ethyl Acetate Analytical Reagent Grade Specifications:
CH3COOCH2CH3 --- Formula Weight 88.11
CAS Number 141-78-6
Suitable for use in ultraviolet spectrophotometry or general use. Product labeling shall designate the one or both of these uses for which suitability is represented on the basis of meeting the relevant requirements and tests. The ultraviolet spectrophotometry requirements include all of the requirements for general use.
Assay: 99.5% CH3COOCH2CH3

Color (APHA): 10
Residue after evaporation: 0.003%
Water (H2O): 0.2%
Titrable acid: 0.0009 meq/g
Substances darkened by sulfuric acid: Passes test.

For Original Monographs of IP Indian Pharmacopoeia BP British Pharmacopoeia USP US Pharmacopoeia FCC Food Grade product, please check with the respective web-pages or books.

We also manufacture and supply as under:

Ethyl Acetate

Aluminum Acetate

Butyl Acetate

Ethyl Acetoacetate

Ethyl 4-Chloroacetoacetate

Ethyl Cyanoacetate

Ethyl Laurate or Ethyl Dodecanoate or Lauric Acid Ethyl Ester

Methyl Acetate

Methyl Cyano Acetate.


Ambernath Mumbai, Ankleshwar Gujarat, India
TEL: (OFFICE) +912223770100, +912223726950
Current Date Time in India GMT+5:30


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Call toll-free 1-877-682-9243 (1-877-MUBYCHEM)

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Last 12 June, 2024

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Ethyl acetate or Ethyl ethanoate SDS, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet


Product Name & Other Names: Ethyl acetate or Ethyl ethanoate.
CAS Number: 141-78-6
EINECS EC Number: 205-500-4
Molecular Formula: C4H8O2
Molecular Weight: 88.10
Relevant uses and uses advised against (if any): Industrial Manufacturing.
Suppliers: As per letterhead.


GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008

Flammable liquids Category 2, H225
Serious eye damage/eye irritation Category 2B, H319
Specific target organ toxicity - single exposure (Category 3), Central nervous system, H336

Labeling according to GHS & Regulation (EC) No 1272/2008

GHS Label Elements
Flammable Liquid

GHS Label Elements

Signal Words (GHS-USA): Danger

Hazard statements (GHS-USA):
H225 Highly flammable liquid and vapor.
H319 Causes serious eye irritation.
H336 May cause drowsiness or dizziness.

Precautionary statements (GHS-USA):
P210: Keep away from heat/sparks/open flames/hot surfaces – No smoking.
P261: Avoid breathing vapors.
P264: Wash … thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P273: Avoid release to the environment.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P302+352: IF ON SKIN: Wash with soap and water.
P305+351+338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do – continue rinsing.
P337+313: If eye irritation persists get medical advice/attention.
P403+235: Store in a well-ventilated place. Keep cool.
P501: Dispose of contents/container to authorized agents only.

Classification according to EU Directives 67/548/EEC or 1999/45/EC:
Hazard Symbols:
F = Flammable.
Xi = Irritant.
Risk Phrases:
R11 Highly flammable.
R36 Irritating to eyes.
R67 Vapors may cause drowsiness and dizziness.


Product Name & Other Names: Ethyl acetate or Ethyl ethanoate.
CAS Number: 141-78-6
EINECS EC Number: 205-500-4

Always seek medical advice after the first aid treatment.

Eye contact: Rinse immediately with plenty of water for 10 minutes at least. Contact a physician if symptoms persist.
Skin contact: Wash thoroughly with soap and water; flush with plenty of water. Take off spoilt clothes. Contact physician if symptoms persist.
Ingestion: Wash the mouth with water; seek medical advice immediately.
Inhalation: Remove from exposure site to fresh air and keep at rest. Obtain medical advice.


Flash point: -20C
Extinguishing media recommended: CO2, foam, dry chemicals, Water spray.
Non recommended: Do not use direct water jet on burning material.
Extinguishing procedures: Closed containers may build up pressure at elevated temperatures. If possible, containers should be cooled with a water spray. For large fires, apply water from as far as possible. Keep containers and surroundings cool with water spray. Beware of vapors accumulating to form explosive concentrations. Vapors can accumulate in low areas.
Extinguishing Media Not recommended: Avoid using solid water jet as it may scatter the fire.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes. Fire-extinguishing work is done from the windward and the suitable fire-extinguishing method according to the surrounding situation is used. Uninvolved persons should evacuate to a safe place.


Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment cleanup procedures and Storage: Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g., sand, earth, diatomaceous earth, vermiculite). Vacuum or sweep up and remove to an approved disposal container. Avoid open flames or other sources of ignition.


Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Do not leave the material container open. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like bases, oxidizing agents, reducing agents. Keep away from ignition sources and naked flame. - No smoking. Take measures to prevent the build-up of electrostatic charge. To avoid ignition of vapors by static electricity discharge, all metal parts of the equipment must be grounded.


Exposure limit values:
USA ACGIH TWA (ppm): 400 ppm
USA OSHA 200 ppm TWA 400 mg/m3 TWA
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full-face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Dust deposits on floors and other surfaces may pick up moisture and cause the surfaces to become slippery and present safety hazards. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.


Appearance: Clear liquid.
Odor: Sweet fruity odor.
Odor threshold: Not available.
pH: Not available.
Relative density: about 0.9
Melting point/freezing point: -84C.
Initial boiling point and boiling range: 77C.
Flash point: -4C Closed cup.
Auto-ignition temperature: 427C.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility(ies): Soluble in water. Miscible with ethanol, acetone, and benzene.
Viscosity: Not available.
Molecular Formula: C4H8O2
Molecular Weight: 88.10


Reactivity: It presents no significant reactivity hazards, by itself or in contact with water. Avoid contact with strong acids, alkali, or oxidizing agents.
Decomposition: Carbon monoxide and unidentified organic compounds may be formed during combustion.
Conditions to avoid: Heat, sparks, open flames, and other ignition sources. Contact with incompatible materials. Avoid Bases, Oxidizing agents, Reducing agents, Direct sunlight.


LD 50 ORAL/RAT (mg/Kg): 5620 mg/kg
LD 50 DERMAL/RABBIT (mg/Kg) .18000 mg/kg.
LC50 INHALATION MOUSE: 45000 ppm/2h
Carcinogenic Effects: Not a reported carcinogen by NTP, ACGIH, OSHA.
Mutagenic Effects: Not available.
Developmental Toxicity: Not available.
Reproductive Effects: No information available.
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.


Toxicity to fish LC50: flow-through test LC50 - Pimephales promelas (fathead minnow) - 230 mg/l - 96 h.
Results of PBT and vPvB assessment: This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.


In accordance with local environmental laws. Avoid disposing into drainage systems and into the environment.


DOT USA TDG Canada & ADR/RID Europe
UN-No: UN 1173
Proper Shipping Name: Ethyl acetate
Hazard Class: 3, Packing Group: II.
UN-No: UN 1173
Proper Shipping Name: Ethyl acetate
Hazard Class: 3, Packing Group: II.
UN-No: UN 1173
Proper Shipping Name: Ethyl acetate
Hazard Class: 3, Packing Group: II.


SARA 311/312 Hazards
: Fire Hazard, Immediate Acute Health Hazard. See section 2.
California Prop. 65 Components: This product does not contain any chemicals known to State of California to cause cancer, birth defects, or any other reproductive harm.

Section 16 - Additional Information

European Labeling in Accordance with EC Directives
H225 Highly flammable liquid and vapor.
H319 Causes serious eye irritation.
H336 May cause drowsiness or dizziness.

Classification according to EU Directives 67/548/EEC or 1999/45/EC:
Hazard Symbols:
F = Flammable.
Xi = Irritant.
Risk Phrases:
R11 Highly flammable.
R36 Irritating to eyes.
R67 Vapors may cause drowsiness and dizziness.

Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.