Cycloheximide or 3-[2-(3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl]glutarimide or Actidione or Naramycin A Manufacturers, with SDS GHS MSDS Sheet |
Supplier, Manufacturer, Exporter of Cycloheximide or 3-[2-(3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl]glutarimide or Actidione or Naramycin A, Muby Chemicals of Mubychem Group, established in 1976, is the original manufacturers of Specialty Chemicals, Pharmaceutical Excipient, Fragrance Food & Flavor chemicals, Reagent Grade Chemicals, Shale Gas Fracturing Chemicals in India. Mubychem Group has several manufacturing facilities spread across Western India and world wide contacts and toll manufacturers. We are exporting globally to countries like USA, Canada, Europe, UAE, South Africa, Tanzania, Kenya, Egypt, Nigeria, Cameroon, Uganda, Turkey, Mexico, Brazil, Chile, Argentina, Dubai, Korea, Vietnam, Thailand, Malaysia, Indonesia, Australia, China, Germany, France, Italy, Portugal, Bangladesh, etc. The products are offered as per required specifications and in correct shape and size in mm or meshs or microns as specified by the buyer. The participating units have one or more accreditations like FDA - cGMP and GLP approval, ISO-9001 Certified, "REACH" Registered, ISO-14001, ISO/IEC 17025, ISO-22000, FSSC 22000, ISO 45001, Kosher Certified, Halal Certified, HACCP, FSSAI. We offer Commercial Pure & IP BP EP Ph Eur USP NF JP FCC Food Grade Analytical Reagent Grades of Chemicals |
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Cycloheximide or 3-[2-(3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl]glutarimide or Actidione or Naramycin A CAS Number 66-81-9, EINECS EC Number: 200-636-0, Molecular Formula: C15H23NO4, Molecular Weight: 281.35, HS Code 29242190
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SDS MSDS Sheet of Cycloheximide or 3-[2-(3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl]glutarimide or Actidione or Naramycin A Manufacturers
Cycloheximide
3-[2-(3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl]glutarimide or Actidione or Naramycin A Suppliers
Cycloheximide or 3-[2-(3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl]glutarimide or Actidione or Naramycin A has been used as a fungicide in agricultural applications. Cycloheximide can be used as an experimental tool in molecular biology to determine the half-life of a protein. It is also used as an anticancer drug.
General Properties and Specifications of Cycloheximide or 3-[2-(3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl]glutarimide or Actidione or Naramycin A:Appearance: White to off-white crystalline powder.
Assay: 95% minimum.
Melting point: 110C to 112C literature.
Solubility: Soluble in DMSO, Ethanol, Water.
Storage: Refrigerate. Shipping may be ambient.
We also manufacture and supply as under:
Manufacturers:
MUBY CHEMICALS
Ambernath Mumbai, Ankleshwar Gujarat, India
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e-mail: us@mubychem.com
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21 April, 2024
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Cycloheximide or 3-[2-(3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl]glutarimide or Actidione or Naramycin A SDS Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet 26-July-23
Section 1. Product Information
Product Name & Other Names: Cycloheximide or 3-[2-(3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl]glutarimide or Actidione or Naramycin A
CAS No.: 66-81-9
EINECS EC Number: 200-636-0
Chemical Formula: C15H23NO4
Molecular Weight: 281.35
Relevant uses and uses advised against (if any): Industrial Manufacturing.
Suppliers: As per letterhead.
Section 2: Hazards Identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008
Acute toxicity, Oral (Category 2), H300
Germ cell mutagenicity (Category 2), H341
Reproductive toxicity (Category 1B), H360D
Chronic aquatic toxicity (Category 2), H411
Labeling according to GHS & Regulation (EC) No 1272/2008
GHS Label Elements  Aquatic Toxicity |
GHS Label Elements |
GHS Label Elements |
Signal Words: Danger
Hazard statements:
H300 Fatal if swallowed.
H341 Suspected of causing genetic defects.
H360D May damage the unborn child
H411 Toxic to aquatic life with long lasting effects.
Precautionary statements:
P260: Do not breathe dust/fume/gas/mist/vapors/spray.
P264: Wash … thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P273: Avoid release to the environment.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P301+310: IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P303+361+353: IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
P333+313: If skin irritation or a rash occurs: Get medical advice/attention.
P304+340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P391: Collect spillage.
P405: Store locked up.
P403+233: Store in a well-ventilated place. Keep container tightly closed.
P501: Dispose of contents/container in accordance with local/regional/national/international regulation.
Classification according to EU Directives 67/548/EEC or 1999/45/EC:
Hazard Symbols:
T+ Very Toxic
N Dangerous for the environment.
Risk Phrases:
R25 Toxic if swallowed.
R46 May cause genetic damage.
R61 May cause harm to the unborn child.
R51/53 = Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Section 3: Composition and Information on Ingredients
Product Name & Other Names: Cycloheximide or 3-[2-(3,5-Dimethyl-2-oxocyclohexyl)-2-hydroxyethyl]glutarimide or Actidione or Naramycin A
CAS No.: 66-81-9
EINECS EC Number: 200-636-0
Section 4. First Aid & Procedure
Always get medical attention after the first aid is over.
Ingestion: Never give anything by mouth to an unconscious person. Get medical attention.
Skin: Immediately flush skin with plenty of water for at least 15 minutes. Remove and wash contaminated clothing and shoes before reuse. Get medical attention if irritation develops.
Eyes: Immediately flush eyes with plenty of water for 15 minutes, occasionally lifting upper and lower eyelids. Hold eyelids apart during irrigation. Get medical attention.
Inhalation: Remove person to fresh air. If breathing is difficult, give oxygen. If not breathing administer artificial respiration. Get medical attention.
Section 5. Fire Fighting Measures
Fire/Explosion: Not considered to be a fire and explosion hazard.
Extinguishing Medium: Water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance/ mixture: Nitrogen oxides and fumes including Carbon monoxide (CO) Carbon dioxide (CO2).
Fire Fighting Instructions: Use suitable protective equipment for surrounding fire.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes. Fire-extinguishing work is done from the windward and a suitable fire-extinguishing method according to the surrounding situation is used. Uninvolved persons should evacuate to a safe place.
Section 6. Spills and Disposals
Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment cleanup procedures and Storage: Do not inhale dust, vapors, mist, or gas. Avoid dust formation. Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g., sand, earth, diatomaceous earth, vermiculite). Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and allow to evacuate as per law.
Section 7. Handling and Storage
Precautions for safe handling: Avoid prolonged or repeated exposure. Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. In case of insufficient ventilation, wear suitable respiratory equipment. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like strong oxidizing agents, strong acids & reducing agents. Storage: Refrigerate. Shipping may be ambient.
Section 8. Exposure Controls & Personal Protection
Exposure Limits: This product does not contain any hazardous materials with occupational exposure limits established by the region-specific regulatory bodies.
Engineering Controls: Use adequate exhaust ventilation to keep airborne concentrations below the allowable exposure limit.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full-face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Section 9. Physical & Chemical Data
Physical State: White to off-white crystalline powder.
Odor: Not available.
Odor threshold: Not available.
pH: Not available.
Relative density: Not available.
Melting point/freezing point: 110C to 112C literature.
Initial boiling point and boiling range: Not available.
Flash point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility: Soluble in DMSO, Ethanol, Water.
Viscosity: Not available.
Chemical Formula: C15H23NO4
Molecular Weight: 281.35
Section 10. Stability and Reactivity
Chemical Stability: Stable under normal temperatures and pressures. Sensitive to light.
Incompatibility (Materials to Avoid): Strong acids, Strong bases, Acid chlorides, Acid anhydrides and strong oxidizing agents & reducing agents.
Conditions to Avoid: Incompatible materials, exposure to moist air or water, excessive heat.
Hazardous Decomposition Products: Fumes including Nitrogen oxides, Carbon monoxide (CO) Carbon dioxide (CO2).
Hazardous Polymerization: Will not occur.
Section 11. Toxicological Information
Toxicity to Animals: LD50 Oral - Rat - 2 mg/kg.
Carcinogenicity: Not listed as a suspected/confirmed carcinogen by NTP, OSHA, IARC.
Germ cell mutagenicity: Suspected of causing genetic defects.
Reproductive toxicity: May damage the unborn child.
Developmental Effects: No information available.
Section 12. Ecological Information
Toxicity to fish: no data available.
Ecotoxicity: Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Bioaccumulative potential: no data available.
Persistence and Degradability: Persistence is unlikely.
Mobility in soil: Will be mobile in the environment due to its water solubility.
PBT and vPvB assessment: no data available.
Environmental Precautions: DO NOT DISCHARGE into drains and rivers.
Section 13. Disposal Suggestions
Dispose of in accordance with all applicable local, state, and federal regulations at an approved waste disposal facility.
Section 14. Transport and Label Information
DOT USA, TDG Canada & ADR/RID Europe:
UN-No UN 2811
Proper Shipping Name: Toxic solid, organic, n.o.s. (Cycloheximide)
Hazard Class 6.1; Packing Group II.
IMDG/IMO & IATA
UN-No UN 2811
Proper Shipping Name: Toxic solid, organic, n.o.s. (Cycloheximide)
Hazard Class 6.1; Packing Group II.
Section 15. Regulatory Information
USA:
SARA 311/312 Hazards: Acute Health Hazard, Chronic Health Hazard. See section 2.
Section 16. Other Information
European Labeling in Accordance with EC Directives:
H300 Fatal if swallowed.
H341 Suspected of causing genetic defects.
H360D May damage the unborn child
H411 Toxic to aquatic life with long lasting effects.
Hazard Symbols:
T+ Very Toxic
N Dangerous for the environment.
Risk Phrases:
R25 Toxic if swallowed.
R46 May cause genetic damage.
R61 May cause harm to the unborn child.
R51/53 = Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Disclaimer:
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Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
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