Calcium Polystyrene Sulfonate or or Calcium Polystyrene Sulphonate BP JP Grade Manufacturers, with SDS GHS MSDS Sheet

Supplier, Manufacturer, Exporter of Calcium Polystyrene Sulfonate BP JP Grade, Muby Chemicals of Mubychem Group, established in 1976, is the original manufacturers of Specialty Chemicals, Pharmaceutical Excipient, Fragrance Food & Flavor chemicals, Reagent Grade Chemicals, Shale Gas Fracturing Chemicals in India. Mubychem Group has several manufacturing facilities spread across Western India and world wide contacts and toll manufacturers. We are exporting globally to countries like USA, Canada, Europe, UAE, South Africa, Tanzania, Kenya, Egypt, Nigeria, Cameroon, Uganda, Turkey, Mexico, Brazil, Chile, Peru, Argentina, Dubai, Korea, Vietnam, Thailand, Malaysia, Indonesia, Australia, China, Germany, France, Italy, Portugal, Bangladesh, etc.

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Calcium Polystyrene Sulfonate or or Calcium Polystyrene Sulphonate: CAS Number: 37286-92-3., EINECS EC Number: yyyyy, Molecular Formula: C8H7CaO3S+, Molecular Weight: 223.3, HS Code ---**

Specifications, Safety Data Sheet, Manufacturing process details, Wholesale retail prices, Uses etc available on these pages for Calcium Polystyrene Sulfonate.

Typical Specifications of Calcium Polystyrene Sulfonate:
Characteristic: A cream to light brown fine powder, free from foreign particles.
Solubility: Practically insoluble in water and in 96% ethanol.
Identifications:
1) The IR spectrum of the sample should be concordant with reference spectrum of Calcium Polystyrene Sulphonate BP grade.
2) Gives characteristic of Calcium Salt.
Fineness: Not more than 1% is retained on 100 mesh BSS 150 micron sieve.
Potassium: <0.1%
Sodium: <0.1%
Arsenic: <1ppm
Heavy Metals: Not more than 10ppm
Styrene: <1ppm
Potassium Exchange Capacity: Each gram exchange not less than 1.3mEq and not more than 2 mEq calculated on dried basis.
Loss on Drying: <8%

Calcium Polystyrene Sulphonate BP
Action and use: Used in the treatment of hyperkalaemia.

DEFINITION
Calcium Polystyrene Sulphonate is a cation-exchange resin prepared in the calcium form containing not less than 6.5% w/w and not more than 9.5% w/w of calcium, calculated with reference to the dried substance. Each g exchanges not less than 1.3 mEq and not more than 2.0 mEq of potassium, calculated with reference to the dried substance.

CHARACTERISTICS
A cream to light brown, fine powder.
Practically insoluble in water and in ethanol (96%).

IDENTIFICATION
A. The infrared absorption spectrum, Appendix II A, is concordant with the reference spectrum of calcium polystyrene sulphonate.
B. Yields reaction C characteristic of calcium salts.

TESTS
Particle size: Not more than 1% w/w is retained on a 150-μm sieve. Use 20 g and sieve for 5 minutes.
Potassium: Not more than 0.1% of K when determined by atomic emission spectrophotometry.
Sodium: Not more than 0.1% of Na when determined by atomic emission spectrophotometry ,
Heavy metals: Heat 4 g until charred, cool, add 4 ml of lead-free nitric acid and 0.5 ml of sulphuric acid drop wise and heat cautiously until white fumes are no longer evolved. Ignite in a muffle furnace at 500C to 600C until a white residue is obtained. Cool, add 4 ml of hydrochloric acid and dilute to 20 ml. The resulting solution complies with limit test A for heavy metals, Appendix VII. Use 2 ml of lead standard solution (10 ppm Pb) to prepare the standard (10 ppm).
Styrene: Carry out the method for liquid chromatography, Appendix III D, using the following solutions. For solution (1) shake 10 g of the substance being examined with 10 ml of acetone for 30 minutes, centrifuge and use the supernatant liquid. Solution (2) contains 0.0001% w/v of styrene in acetone.
The chromatographic procedure may be carried out using (a) a stainless steel column (30 cm × 4 mm) packed with octadecylsilyl silica gel for chromatography (μBondapak C18 is suitable), (b) a mixture of equal volumes of acetonitrile and water as the mobile phase with a flow rate of 2 ml per minute and (c) a detection wavelength of 254 nm. Inject separately 20 μl of each solution. The area of the peak corresponding to styrene in the chromatogram obtained with solution (1) is not greater than the area of the principal peak in the chromatogram obtained with solution (2) (1 ppm).
Potassium exchange capacity: To 3 g of the substance being examined in a dry 250 ml glass-stoppered flask add 100 ml of a solution containing 0.7455% w/v of potassium chloride and 0.4401% w/v of potassium hydrogen carbonate in water (solution A), stopper and shake for 15 minutes. Filter and dilute 2 ml of the filtrate to 1000 ml with water. Determine the concentration of unbound potassium in this solution by atomic emission spectrophotometry, Appendix II D, measuring at 766.5 nm and using solution A suitably diluted with water, to prepare the standard solutions. Calculate the potassium exchange capacity of the substance being examined in milliequivalents taking the concentration of potassium in solution A as 144 milliequivalents of K per litre.
Loss on drying: When dried at 70C at a pressure not exceeding 0.7 kPa for 16 hours, loses not more than 8.0% of its weight. Use 2 g.
Microbial contamination: Carry out a quantitative evaluation for Enterobacteria and certain other Gram-negative bacteria, Appendix XVI B1. 0.01 g of the substance being examined gives a negative result, Table I (most probable number of bacteria per gram fewer than 100).

ASSAY
For calcium: Carefully heat 1 g in a platinum crucible until a white ash is obtained and dissolve in 10 ml of 2 M hydrochloric acid with the aid of heat. Transfer the resulting solution to a conical flask using 20 ml of water. Add 50 ml of 0.05 M disodium edetate, 20 ml of ammonia buffer pH 10.9 and titrate the excess of disodium edetate with 0.02 M zinc sulphate, using a 0.5% w/v solution of mordant black 11 in ethanol (96%) as indicator to a red purple end point.
Each ml of 0.05 M disodium edetate VS is equivalent to 2.004 mg of Ca.

STORAGE
Calcium Polystyrene Sulphonate should be kept in an airtight container.

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Calcium Polystyrene Sulphonate or Calcium Polystyrene Sulfonate SDS, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet 07-Oct-20

Product Name & Other Names: Calcium Polystyrene Sulfonate or Calcium Polystyrene Sulphonate
CAS #: 37286-92-3
Relevant uses and uses advised against (if any): Industrial use only.
Supplier: As per letterhead.

GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008

Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
This substance is not classified as dangerous according to Directive 67/548/EEC.

Hazards not otherwise classified (HNOC):
The toxicological properties of this material have not been fully investigated.
May causes mild skin irritation.
May causes mild eye irritation.
May cause irritation of digestive tract.
May cause irritation of respiratory tract.

Precautionary statements:
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P262: Do not get in eyes, on skin, or on clothing.
P281: Use personal protective equipment as required.
P302+P352: IF ON SKIN: Wash with plenty of soap and water.
P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+313: If eye irritation persists get medical advice/attention.

Product Name & Other Names: Calcium Polystyrene Sulfonate or Calcium Polystyrene Sulphonate
CAS #: 37286-92-3
% by Weight: 90-100%. Mainly water as other substance.

First aid: Wash exposed area with soap and water.
Eyes: Wash eyes with plenty of water for at least 15 minutes, lifting lids occasionally. Seek Medical Aid.
Inhalation: Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Ingestion: If swallowed, induce vomiting immediately after giving two glasses of water. Never give anything by mouth to an unconscious person.

Flammability of the Product: Non-flammable.
Products of Combustion: Calcium oxide with oxides of sulphur, carbon and fumes.
Extinguisher Media: Use media suitable to extinguish surrounding fire. Use alcohol-resistant foam, dry chemical, or carbon dioxide.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes.

Personal precautions, protective equipment, and emergency procedures: Ventilate area of leak or spill. Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment Cleanup procedures and Storage:
Small Spill: Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to legal requirements.
Large Spill: Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g. sand, earth, diatomaceous earth, vermiculite). Vacuum or sweep-up and remove to an approved disposal container. Finish cleaning by spreading water on the contaminated surface and allow to evacuate as per law.

Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. In case of insufficient ventilation, wear suitable respiratory equipment. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like strong oxidizing agents and acids. Avoid moisture.

Engineering Controls: Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits. If user operations generate dust, fume, or mist, use ventilation to keep exposure to airborne contaminants below the exposure limit.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Dust deposits on floors and other surfaces may pick up moisture and cause the surfaces to become slippery and present safety hazards. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.

Appearance: Cream to light brown solid.
Odor: Not available.
Odor threshold: Not available.
pH: Not available.
Relative density: around 0.7 to 0.8
Melting point/freezing point: Not available.
Initial boiling point and boiling range: Not available.
Flash point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility(ies): Insoluble in cold water and alcohol.
Viscosity: Not available.
Molecular Formula: C8H7CaO3S+
Molecular Weight: 223.3

Stability: Stable under ordinary conditions of use and storage.
Conditions of Instability: Incompatible materials
Incompatibility with various substances: Reactive with oxidizing agents.
Corrosivity: Non-corrosive in presence of glass.
Polymerization: Will not occur.

Toxicity to Animals: LD50 (Oral) Rat >5000 mg/kg
Carcinogenicity: Not available.
Mutagenic Effects: Not available.
Teratogenic Effects: Not available.
Developmental Toxicity: Not available.
Reproductive Effects: No information available.

Ecotoxicity: The product is not expected to be harmful to marine life.
Persistence and Degradability: No information available.
Mobility: No information available.
Bioaccumulation/ Accumulation: No information available.
Results of PBT and vPvB assessment: No data available for assessment.

Waste Disposal: Waste must be disposed of in accordance with federal, state, and local environmental control regulations.

DOT USA & ADR/RID Europe: Not dangerous goods
IMDG: Not dangerous goods
IATA: Not dangerous goods.

USA Regulations:
OSHA Hazards: No known OSHA hazards
SARA 302: No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302.
SARA 313: This material does not contain any chemical components with known CAS numbers that exceed the threshold (De Minimis) reporting levels established by SARA Title III, Section 313.

Disclaimer:
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Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
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