Meglumine or N-methyl d-glucamine or N-Methylglucamine Manufacturers, with SDS GHS MSDS Sheet |
Supplier, Manufacturer, Exporter of Meglumine or N-methyl d-glucamine or N-Methylglucamine, Muby Chemicals of Mubychem Group, established in 1976, is the original manufacturers of Specialty Chemicals, Pharmaceutical Excipient, Fragrance Food & Flavor chemicals, Reagent Grade Chemicals, Shale Gas Fracturing Chemicals in India. Mubychem Group has several manufacturing facilities spread across Western India and world wide contacts and toll manufacturers. We are exporting globally to countries like USA, Canada, Europe, UAE, South Africa, Tanzania, Kenya, Egypt, Nigeria, Cameroon, Uganda, Turkey, Mexico, Brazil, Chile, Argentina, Dubai, Korea, Vietnam, Thailand, Malaysia, Indonesia, Australia, China, Germany, France, Italy, Portugal, Bangladesh, etc. The products are offered as per required specifications and in correct shape and size in mm or meshs or microns as specified by the buyer. The participating units have one or more accreditations like FDA - cGMP and GLP approval, ISO-9001 Certified, "REACH" Registered, ISO-14001, ISO/IEC 17025, ISO-22000, FSSC 22000, ISO 45001, Kosher Certified, Halal Certified, HACCP, FSSAI. We offer Commercial Pure & IP BP EP Ph Eur USP NF JP FCC Food Grade Analytical Reagent Grades of Chemicals |
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Meglumine or N-methyl d-glucamine or N-Methylglucamine or 1-Deoxy-1-(methylamino)-D-glucitol: CAS Number: 6284-40-8, EINECS EC Number: 228-506-9, Molecular Formula: C7H17NO5, Molecular Weight: 195.21, HS Code 2922 19 00
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SDS MSDS Sheet of Meglumine or N-methyl d-glucamine or N-Methylglucamine Manufacturers
Meglumine
N-methyl d-glucamine or N-Methylglucamine or 1-Deoxy-1-(methylamino)-D-glucitol Pure Suppliers
Meglumine or 1. N-Methyl-D-glucamine or N-Methylglucamine or 1-Deoxy-1-(methylamino)-D-glucitol is an amino sugar derived from glucose. 1. N-Methyl-D-glucamine or Meglumine can be used as a contrast agent and surfactant for medical use. 1-Deoxy-1-(methylamino)-D-glucitol. A derivative of sorbitol.
General Properties and Specifications of N-methyl d-glucamine or Meglumine or N-Methylglucamine or 1-Deoxy-1-(methylamino)-D-glucitol:
Appearance: White crystalline powder.
Purity: 99.0%-100.5%
Loss on drying: 1% maximum.
Residue on ignition: 0.1% maximum.
Heavy metals: 20 ppm maximum.
Melting point: 128C to 132C.
Solubility: Soluble in water.
Meglumine USP Grade Specifications:
C7H17NO5 --- 195.21
d-Glucitol, 1-deoxy-1-(methylamino)-;
1-Deoxy-1-(methylamino)-d-glucitol CAS 6284-40-8.
DEFINITION
Meglumine contains NLT 99.0% and NMT 100.5% of meglumine (C7H17NO5), calculated on the dried basis.
IDENTIFICATION
A.
Sample solution: Transfer 250 mg to a dry, 50-mL centrifuge tube, add 500 mg of sodium metaperiodate, then add 5 mL of water rapidly in one portion. Allow to stand undisturbed.
Analysis: The solution instantly turns yellow, and heat is produced. The color then changes from deep yellow to orange-brown (rust), and after 20 min, the rust-colored solution is cloudy. Then add 2 mL of 2.5 N sodium hydroxide.
Acceptance criteria: The mixture turns bright yellow and becomes clear.
Residue on Ignition: NMT 0.1%
Absence of Reducing Substances
Sample solution: 50 mg/mL
Analysis: To 5 mL of Sample solution add 5 mL of alkaline cupric tartrate TS, and heat to boiling.
Acceptance criteria: The color of the solution does not change.
Completeness and Color of Solution: To pass the test.
Loss on Drying: NMT 1.0% at 105C to constant weight.
Melting Range or Temperature: 128C to 132C.
Optical Rotation, Specific Rotation:
Sample solution: 100 mg/mL, undried, in water.
Acceptance criteria: -15.7° to -17.3°
Packaging and Storage: Preserve in well-closed containers.
Meglumine BP Ph Eur Grade Specifications:
C7H17NO5 --- 195.2 --- CAS 6284-40-8
Action and use: Organic base used in the preparation of organic acids.
DEFINITION
1-Deoxy-1-(methylamino)-D-glucitol.
Content: 99.0 per cent to 101.0 per cent (dried substance).
CHARACTERS
Appearance: White or almost white, crystalline powder.
Solubility: Freely soluble in water, sparingly soluble in ethanol (96 per cent), practically insoluble in methylene chloride.
Mp: About 128C.
IDENTIFICATION
Infrared absorption spectrophotometry: Comparison meglumine CRS.
TESTS
Solution S: Dissolve 20.0 g in distilled water and dilute to 100.0 mL with the same solvent.
Appearance of solution: The solution is clear and its absorbance at 420 nm is not greater than 0.03.
Dissolve the residue obtained in the test for loss on drying in water and dilute to 10 mL with the same solvent.
Specific optical rotation: -16.0 to -17.0 (dried substance).
Reducing substances: Maximum 0.2 per cent, expressed as glucose.
Chlorides: Maximum 100 ppm.
Sulfates: Maximum 150 ppm.
Aluminium: Maximum 5 ppm.
Iron: Maximum 10 ppm.
Nickel: Maximum 5 ppm.
Sulfated ash: Maximum 0.1 per cent, determined on 1.0 g.
Bacterial endotoxins: Less than 1.5 IU/g, if intended for use in the manufacture of parenteral preparations without a further appropriate procedure for the removal of bacterial endotoxins.
For Original Monographs of IP Indian Pharmacopoeia BP British Pharmacopoeia USP US Pharmacopoeia FCC Food Grade product, please check with the respective web-pages or books.
We also manufacture and supply as under:
1,2-Dioleyloxy-3-dimethylamino-propane or Cationics DODMA
N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide
Manufacturers:
MUBY CHEMICALS
Ambernath Mumbai, Ankleshwar Gujarat, India
TEL: (OFFICE) +912223770100, +912223726950
Current Date Time in India GMT+5:30
e-mail: info@mubychem.com
USA, Canada, Mexico and other American
neighbouring buyers may
e-mail: us@mubychem.com
Call toll-free 1-877-682-9243 (1-877-MUBYCHEM)
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7 May, 2024
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Meglumine or N-methyl d-glucamine or N-Methylglucamine or 1-Deoxy-1-(methylamino)-D-glucitol SDS, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet 04-Apr-21
Section 1: Chemical Product and Company Identification
Product Name & Other Names: Meglumine or N-methyl d-glucamine or N-Methylglucamine or 1-Deoxy-1-(methylamino)-D-glucitol.
CAS Number: 6284-40-8
EINECS EC Code: 228-506-9
Molecular Formula: C7H17NO5
Molecular Weight: 195.21
Relevant uses and uses advised against (if any): Industrial Manufacturing.
Suppliers: As per letterhead.
Section 2: Hazards Identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Hazard Class and Category Code(s), Regulation (EC) No 1272/2008 (CLP)
Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
This substance is not classified as dangerous according to Directive 67/548/EEC.
Labeling Regulation EC 1272/2008 (CLP) & GHS
GHS Label Elements NONE |
Signal Word: None
Hazards not otherwise classified (HNOC):
May causes mild skin irritation.
May causes mild eye irritation.
Precautionary statements:
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P262: Do not get in eyes, on skin, or on clothing.
P281: Use personal protective equipment as required.
P302+P352: IF ON SKIN: Wash with plenty of soap and water.
P303+P361+P353: IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+313: If eye irritation persists get medical advice/attention.
Section 3: Composition and Information on Ingredients
Product Name & Other Names: Meglumine or N-methyl d-glucamine or N-Methylglucamine or 1-Deoxy-1-(methylamino)-D-glucitol.
CAS Number: 6284-40-8
EINECS EC Code: 228-506-9
Section 4: First Aid Measures
Always seek medical advice after the first aid treatment.
Skin: Rinse with water. Soap may be used. Seek Medical Aid.
Eyes: Wash eyes with plenty of water for at least 15 minutes, lifting lids occasionally. Seek Medical Aid.
Inhalation: Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Ingestion: If swallowed, induce vomiting immediately after giving two glasses of water. Never give anything by mouth to an unconscious person.
Section 5: Fire and Explosion Data
Flammability of the Product: Flammable in high concentration of dust in air.
Products of Combustion: Carbon oxides, Nitrogen oxides (NOx) and fumes.
Fire Fighting Media and Instructions: Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. Use extinguishing measures that are appropriate to local circumstances and the surrounding environment. Wear self-contained breathing apparatus for firefighting if necessary.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes. Fire-extinguishing work is done from the windward and the suitable fire-extinguishing method according to the surrounding situation is used. Uninvolved persons should evacuate to a safe place.
Section 6: Accidental Release Measures
Personal precautions, protective equipment and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil or water sources.
Methods and materials used for containment Cleanup procedures and Storage:
Small Spill: Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to legal requirements.
Large Spill: Contain spilled material. Do not inhale vapors, mist, or gas. Avoid dust formation. Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose as per law.
Section 7: Handling and Storage
Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. Wash thoroughly after handling. Do not drink, eat or smoke while handling. Avoid contact with skin, eyes and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cold, dry and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Do not leave the material container open. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like oxidizing agents. Hygroscopic. Air sensitive.
Section 8: Exposure Controls/Personal Protection
Exposure Guidelines: This product, as supplied, does not contain any hazardous materials with occupational exposure limits established by the region specific regulatory bodies.
Engineering Controls: Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to airborne contaminants below the exposure limit.
Engineering Controls: Showers, Eyewash stations and Ventilation systems
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Dust deposits on floors and other surfaces may pick up moisture and cause the surfaces to become slippery and present safety hazards. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.
Section 9: Physical and Chemical Properties
Physical state and appearance: White crystalline powder.
Odor: Not available.
Odor threshold: Not available.
pH (5% soln/water): Not available.
Relative density: Not available.
Melting point/freezing point: 128C to 132C.
Initial boiling point and boiling range: Not available.
Flash point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility: Soluble in water. Sparingly soluble in ethanol (96 per cent). Practically insoluble in methylene chloride.
Viscosity: Not available.
Molecular Formula: C7H17NO5
Molecular Weight: 195.21
Section 10: Stability and Reactivity Data
Stability: It is stable in room temperature in closed containers under normal storage & handling.
Conditions of instability: Incompatible materials, Moisture. Hygroscopic. Air sensitive.
Incompatibility with various substances: Avoid high temperatures, sparks, open flames. Avoid contact with strong oxidizing agents.
Polymerization: Will not occur.
Section 11: Toxicological Information
LD50 Oral Rat: >5000 mg/kg.
LD50 Oral Rabbit: >5000 mg/kg.
Carcinogenic Effects: Not a reported carcinogen by IARC, NTP, ACGIH, OSHA.
Mutagenic Effects: Not available.
Developmental Toxicity: Not available.
Reproductive Effects: No information available.
Section 12: Ecological Information
Toxicity to fish: Not available.
BOD5 and COD: Not available.
Persistence and Degradability: It is expected to be degradable.
Mobility: Likely to be mobile.
Results of PBT and vPvB assessment: No data available for assessment.
Section 13: Disposal Considerations
Waste Disposal: Waste must be disposed of in accordance with federal, state and local environmental control regulations.
Section 14: Transport Information
DOT USA, TDG Canada & ADR/RID Europe: Not dangerous goods.
IMDG/IMO: Not dangerous goods.
IATA/ICAO: Not dangerous goods.
Section 15: Other Regulatory Information
USA Regulations:
Section 302: No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302.
Section 313: No chemicals are reportable under Section 313.
California Prop 65: None of the chemicals in this product are listed.
Disclaimer:
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Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
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