Triclosan or 5-Chloro-2-(2,4-dichlorophenoxy)phenol Manufacturers, with SDS GHS MSDS Sheet

Supplier, Manufacturer, Exporter of Triclosan, Muby Chemicals of Mubychem Group, established in 1976, is the original manufacturers of Specialty Chemicals, Pharmaceutical Excipient, Fragrance Food & Flavor chemicals, Reagent Grade Chemicals, Shale Gas Fracturing Chemicals in India. Mubychem Group has several manufacturing facilities spread across Western India and world wide contacts and toll manufacturers. We are exporting globally to countries like USA, Canada, Europe, UAE, South Africa, Tanzania, Kenya, Egypt, Nigeria, Cameroon, Uganda, Turkey, Mexico, Brazil, Chile, Argentina, Dubai, Korea, Vietnam, Thailand, Malaysia, Indonesia, Australia, China, Germany, France, Italy, Portugal, Bangladesh, etc.

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Triclosan or 5-Chloro-2-(2,4-dichlorophenoxy)phenol: CAS Number: 3380-34-5, EINECS EC Number: 222-182-2, Molecular Formula: C12H7Cl3O2, Molecular Weight: 289.54, HS Code ---**

Specifications, Safety Data Sheet, Manufacturing process details, Wholesale retail buy sell prices, Uses etc available on line in these pages for Triclosan or 5-Chloro-2-(2,4-dichlorophenoxy)phenol.

Triclosan (sometimes abbreviated as TCS) is an antibacterial and antifungal agent present in some consumer products, including shampoos, deodorants, toothpastes, mouthwashes, cleaning supplies, pesticides, soaps, detergents, toys, and surgical cleaning treatments. In surgery, triclosan coated sutures reduce the risk of surgical site infection.

General Properties and Specifications of Triclosan or 5-Chloro-2-(2,4-dichlorophenoxy)phenol:
Appearance: White solid.
Assay: 99% minimum.
Relative density: 1.49
Melting point: 55C to 57C
Boiling point: 120C starts decomposing.

Specifications of Triclosan USP Grade:
C12H7Cl3O2 --- 289.54
Phenol, 5-chloro-2-(2,4-dichlorophenoxy)-.
2,4,4′-Trichloro-2′-hydroxydiphenyl ether --- [CAS 3380-34-5].
Triclosan contains not less than 97.0 percent and not more than 103.0 percent of C12H7Cl3O2, calculated on the anhydrous basis.

Packaging and storage: Preserve in tight, light-resistant containers.
Identification:
A: Infrared Absorption.
B: The retention time of the major peak in the chromatogram of the Assay preparation corresponds to that in the chromatogram of the Standard preparation, as obtained in the Assay.

Water Determination: not more than 0.1%.
Completeness of solution: A solution of 1.40 g of Triclosan in 10 mL of acetone is clear.
Related compounds: To pass the test.
Not more than 0.1% of any individual impurity is found; and not more than 0.5% of total impurities is found.
Limit of monochlorophenols and 2,4-dichlorophenol: To pass the test.
Limit of 1,3,7-trichlorodibenzo-p-dioxin, 2,8-dichlorodibenzo-p-dioxin, 2,8-dichlorodibenzofuran, and 2,4,8-trichlorodibenzofuran: To pass the test.
Not more than 0.25 ppm of 2,8-dichlorodibenzofuran is found; not more than 0.5 ppm of 2,4,8-trichlorodibenzofuran is found; not more than 0.25 ppm of 1,3,7-trichlorodibenzo-p-dioxin is found; and not more than 0.5 ppm of 2,8-dichlorodibenzo-p-dioxin is found.
Limit of 2,3,7,8-tetrachlorodibenzo-p-dioxin and 2,3,7,8-tetrachlorodibenzofuran: To pass the test.

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Triclosan or 5-Chloro-2-(2,4-dichlorophenoxy)phenol SDS GHS, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet 22-Nov-20

Product Name & Other Names: Triclosan or 5-Chloro-2-(2,4-dichlorophenoxy)phenol.
CAS No.: 3380-34-5
EINECS: EC Number: 222-182-2
Molecular Weight: 289.54
Chemical Formula: C12H7Cl3O2
Relevant uses and uses advised against (if any): Industrial use only.
Supplier: As per letterhead.

GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008

Skin corrosion/irritation Category 2, H315
Serious eye damage/eye irritation Category 2A, H319
Hazardous to the aquatic environment, long-term hazard Category 1, H410

Hazard statements:
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H410: Very Toxic to aquatic life with long lasting effects.

Precautionary statements:
P260: Do not breathe dust/fume/gas/mist/vapors/spray.
P262: Do not get in eyes, on skin, or on clothing.
P264 Wash thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P273: Avoid release to the environment.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P314: Get medical advice/attention if you feel unwell.
P302+P352: IF ON SKIN: Wash with plenty of soap and water.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P362: Take off contaminated clothing and wash before reuse.
P332+P313: If skin irritation occurs: Get medical advice/attention.
P337+P313: If eye irritation persists: Get medical advice/ attention.
P391: Collect spillage.
P405: Store locked up.
P501: Dispose of contents/container in accordance with local/regional/national/international regulation.

Classification according to EU Directives 67/548/EEC or 1999/45/EC:
Hazard Symbols:
Xi Irritant
N Dangerous for the environment
Risk Phrases:
R36/38: Irritating to eyes and skin
R50/53: Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.

Product Name & Other Names: Triclosan or 5-Chloro-2-(2,4-dichlorophenoxy)phenol.
CAS No.: 3380-34-5
EINECS: EC Number: 222-182-2

Always seek medical attention after first aid measures are provided.
Inhalation: Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.
Ingestion: Never give anything by mouth to an unconscious person. Get medical attention.
Skin Contact: Wipe off excess material from skin then immediately flush skin with plenty of water for at least 15 minutes. Remove contaminated clothing and shoes. Get medical attention. Wash clothing before reuse. Thoroughly clean shoes before reuse.
Eye Contact: Immediately flush eyes with plenty of water for at least 15 minutes, lifting lower and upper eyelids occasionally. Get medical attention immediately.

Flammability of the Product: May be combustible at high temperature.
Products of Combustion: Carbon dioxide, Carbon monoxide, Hydrogen Chlorides, Fumes.
Fire: Flammable in the presence of open flame.
Explosion: Slightly explosive in presence of heat.
Fire Extinguishing Media: Use any means suitable for extinguishing surrounding fire. Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes. Fire-extinguishing work is done from the windward and the suitable fire-extinguishing method according to the surrounding situation is used. Uninvolved persons should evacuate to a safe place. On decomposition it may emit hydrogen chloride. Containers may explode on heating.

Personal precautions, protective equipment and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Ensure adequate ventilation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil or water sources.
Methods and materials used for containment Cleanup procedures and Storage:
Small Spill: Contain spilled material. Avoid dust formation. Avoid breathing dust. Ensure adequate ventilation. Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to local and regional authority requirements.
Large Spill: Avoid touching the spilled material. Do not let the product enter drains. Use a shovel to put the material into a convenient waste disposal container. Do not contaminate the environment.

Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. In case of insufficient ventilation, wear suitable respiratory equipment. Wash thoroughly after handling. Do not drink, eat or smoke while handling. Avoid contact with skin, eyes and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cool, dry and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Do not leave the material container open. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like strong oxidizing agents.

Airborne Exposure Limits: Although up to 10mg/m3 is prescribed in some regulations, better limit it to 2mg/m3.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.

Appearance: White solid.
Odor: Not available.
Odor threshold: Not available.
pH: Not available.
Relative density: 1.49
Boiling Point: 120C starts decomposing.
Melting Point: 55C to 57C.
Flash point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility: It is slightly soluble in water.
Viscosity: Not available.
Molecular Weight: 289.54
Chemical Formula: C12H7Cl3O2

Stability: Stable under ordinary conditions of use and storage.
Hazardous Decomposition Products: It emits Carbon dioxide, Carbon monoxide, Hydrogen Chlorides & Fumes.
Hazardous Polymerization: Will not occur.
Incompatibilities: Strong oxidizing agents.
Conditions to Avoid: Incompatibles and moisture.

Toxicity data
Oral-Rat LD50 3700 mg kg-1
Dermal - Rabbit LD50 - 9.300 mg/kg
Carcinogenic Effects: Not know as carcinogen as per IARC.
Mutagenic Effects: Not available.
Teratogenic Effects: Not available.
Developmental Toxicity: Not available.

Toxicity to fish: LC50 - Oncorhynchus mykiss (rainbow trout) - 0,288 mg/l - 96,0 h.
Toxicity to daphnia and other aquatic invertebrates: EC50 - Daphnia magna (Water flea) - 0,39 mg/l - 48 h.
Environmental Fate: Not available.
Products of Biodegradation: Possibly hazardous short-term degradation products are not likely. However, long term degradation products may arise.
Toxicity of the Products of Biodegradation: The products of degradation are less toxic than the product itself.
Mobility in soil: No data available.
Persistence and degradability: No data available.

Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. Processing use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose of container and unused contents in accordance with federal, state and local requirements.

DOT USA, TDG Canada & ADR/RID Europe:
UN number: 3077
UN proper shipping name Environmentally hazardous substance, solid, n.o.s. (5-Chloro-2-(2,4dichlorophenoxy)phenol)
Transport hazard class(es): 9
Packaging group: III
IMDG/IMDG & IATA/ICAO
UN number: 3077
UN proper shipping name: Environmentally hazardous substance, solid, n.o.s. (5-Chloro-2-(2,4dichlorophenoxy)phenol)
Transport hazard class(es): 9
Packaging group: III.

USA:
SARA 302 Components: Not subject to the reporting requirements of SARA Title III, Sec.: 302.
SARA 313 Components: No chemicals are reportable under Section 313.
SARA 311/312 Hazards: Immediate Health Hazard: Acute
California prop. 65:Contains no chemical subject to California Prop 65.

European Labeling in Accordance with EC Directives:
H315 = Causes skin irritation.
H319 = Causes serious eye irritation.
H410 = Very Toxic to aquatic life with long lasting effects.

Classification according to EU Directives 67/548/EEC or 1999/45/EC:
Hazard Symbols:
Xi Irritant
N Dangerous for the environment
Risk Phrases:
R36/38 - Irritating to eyes and skin
R50/53 - Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.

Disclaimer:
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Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
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